• Journal of Korea Society of Industrial Information Systems
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• v.12 no.5
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• pp.183-200
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• 2007

This study examines the relationships between typical anticipated benefit factors of introducing online business activities by traditional brick-and-mortar shipping and port logistics companies and their performance in marketing mix and global competitiveness. Three major benefit factors were derived including improved trust, information acquiring and limitation of offline business activities. The three empirically derived critical synergy factors were then used to examine how they improve the firms performance in marketing mix and global competitiveness. The results of structural equation modeling method show that the anticipated benefit factors significantly influence the firms' performance in marketing mix. Subsequently, marketing mix significantly influence the firms' global competitiveness. The results provide useful guidelines for the shipping and port logistics firms to develop appropriate marketing mix strategies to improve their global competitiveness.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.8 no.2
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• pp.161-173
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• 1996

Two-dimensional numerical models with 1$^{\circ}$ and 1/3$^{\circ}$ resolution have been established to investigate the Ma distribution of global ocean tides. Especially, a 1/3$^{\circ}$ numerical model in this study has the most fine resolution among the existing global tidal model and it has been applied to the computation of detailed tidal distributions in the marginal seas and the shelf seas. Tidal characteristics in shallow areas could be hardly interpreted with the existing global chart due to the low resolution. The Ma tidal charts obtaind by 1$^{\circ}$ and 1/3$^{\circ}$ numerical model have been compared with the existing global maps and the altimetry-derived tidal charts. Also, the computed harmonic constants have been compared with the pelagic observations. The results obtained by 1/3$^{\circ}$ numerical model show better agreement with the existing global charts and the observed data than those obtained by 1$^{\circ}$ model. The possibility has been presented that the results obtained by 1/3$^{\circ}$ model can provide the open boundary conditions of the regional tidal numerical model.

• Korean Journal of Pharmacognosy
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• v.42 no.3
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• pp.246-252
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• 2011

Korean mistletoe Lectin (KML-C) is composed of A and B sub-chain. B chain binds to carbohydrates on cell surface and A chain hinders translation and induces an apoptosis as a RIP (ribosome inactivating protein). KML-C has very strong biological activities, it has seriously limits to use as a cancer therapy or adjuvant because of its toxicity to normal cells. This study is therefore conducted to see if B chain of KML-C might have immunological activity, especially adjuvant activities with less toxicity. We isolated B chain from KML-C using the lactose affinity chromatography, and examined their immunoadjuvant activity. The isolated B-chain did not show any cytotoxicity against tumor cell, RAW264.7, and P388D1 while KML-C had a very strong toxicity. This non-toxic effect was observed also by in-vivo study. Both humoral and cellular immunities were observed ; the antibody titer was increased when the mice were immunized with B-chain used as adjuvant like Freund's adjuvant, indicating that B chain of mistletoe lectin alone might be used for adjuvant; it also increased DTH in cellular immunity. These results suggest that B-chain of KML-C might be used for adjuvant used for the production of antibody or vaccine with less toxicity.

• Nutrition Research and Practice
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• v.7 no.4
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• pp.281-286
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• 2013

We examined the effect of parental folate deficiency on the folate content, global DNA methylation, folate receptor-alpha (FR${\alpha}$), insulin-like-growth factor-2 (IGF-2) and -1 receptor (IGF-1R) in the liver and plasma homocysteine in the postnatal rat. Male and female rats were randomly fed a folic acid-deficient (paternal folate-deficient, PD and maternal folate-deficient, MD), or folic acid-supplemented diet (paternal folate-supplemented, PS and maternal-folate-supplemented, MS) for four weeks. They were mated and grouped accordingly: $PS{\times}MS$, $PS{\times}MD$, $PD{\times}MS$, and $PD{\times}MD$. Pups were killed on day 21 of lactation. The hepatic folate content was markedly reduced in the $PD{\times}MD$ and $PS{\times}MD$ and $PD{\times}MS$ as compared with the $PS{\times}MS$ group. The hepatic global DNA methylation was decreased in the $PD{\times}MS$ and $PS{\times}MD$ groups as much as in the $PD{\times}MD$ group, and all the three groups were significantly lower as compared to the $PS{\times}MS$ group. There were no significant differences in the hepatic FR${\alpha}$, IGF-2 and IGF-1R expressions among the groups. Positive correlations were found between the hepatic folate content and global DNA methylation and protein expressions of FR${\alpha}$, IGF-2 and IGF-1R, whereas an inverse correlation was found between hepatic folate content and plasma homocysteine level in the 3-week-old rat pup. The results of this study show that both paternal and maternal folate deficiency at mating can influence the folate content and global DNA methylation in the postnatal rat liver.

• Journal of Aerospace System Engineering
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• v.14 no.3
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• pp.32-41
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• 2020

The International Civil Aviation Organization (ICAO) in 2015 proposed a road-map for the global recognition system of the Approved Maintenance Organization (AMO) fto mitigate the redundant work and regulatory burdens of the aviation industry and authorities on the certification and oversight activities of the State of Registry. Since then, the ICAO standards and guidelines have been revised accordingly with the goal of implementing the system in 2024. Korea should actively prepare for this AMO global recognition system to cope with the ICAO road-map appropriately as well as to develop the Maintenance Repair Overhaul (MRO) industry. Thus, this paper focused on the ratings and limitations system, a key element of the AMO, and proposes the improvement of domestic regulatory/administrative rules necessary for the global recognition system, through the review of newly established ICAO standards/guidelines and the comparative analysis of leading aviation countries' and Korean system/requirements.

• Proceedings of the Korea Information Processing Society Conference
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• 2012.11a
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• pp.1507-1510
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• 2012

본 논문은 EPS(전자식 파워 스티어링)에 사용되는 Torque and Angle sensor 의 절대각 신뢰성 보증 방식에 관한 것으로, Inductive 방식의 센서에서 절대각 신호 신뢰성 보증에 대한 효과적인 방법을 제시한다. 전동식 파워 스티어링 시스템의 ECU(전자제어유닛)는 조타각도를 출력하는 2 개의 소자에서 버니어 알고리즘을 통해 360 도 이상의 멀티 조타각을 인식하게 된다. 토크&조향각 센서는 절대 조향각을 계산하는 1 개의 Hall IC 소자 신호와, 상대 조향각을 계산하는 ASIC 소자 신호를 사용하여 멀티 조타각을 인식한다. 인식된 조타각이 추가적인 검증 절차 없이 제어에 사용된다면, 센서의 이상 발생 시에 운전자의 조타감을 불편해질 수 있고, 나아가서는 차량사고의 위험을 발생시킬 수 있다.따라서 차량 거동 시 절대 조향각의 신뢰성 검증은 제어와 동시에 항상 요구되어야 한다. 특히, 유럽/미국 업계의 ISO 26262 표준 도입에 따라 절대 조향각의 높은 신뢰성이 요구된다. 본 논문에서는 이러한 요구사항을 만족하기 위해 측정된 절대각 신호를 기준으로 상대각 신호 2 개를 측정에 사용하고, Driving 시에도 절대각 기준의 신뢰도 향상을 위해 절대각 신호 1 개를 비교기로 사용한다. 최적화된 에러 기준을 근거로 절대 조향각 신호의 신뢰성을 보장하는 방법을 제안한다. 이러한 방법을 적용한다면, 정확하고 안정적으로 조타각을 결정함으로써 EPS 안전성 확보에 도움을 줄 수 있다.

• Parasites, Hosts and Diseases
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• v.59 no.2
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• pp.121-129
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• 2021

We aimed to explore the population dynamics of snail in 3 sites of the White Nile in Sudan. More specifically, we aimed to investigate the annual patterns of snail populations that act as intermediate hosts of schistosomes and monthly snail infection rates and ecological characteristics presumably related to snail populations. We collected snails for 1 year monthly at 3 different shore sites in the vicinity of El Shajara along the White Nile river in Khartoum State, Sudan. In addition, we measured air and water temperatures, water turbidities, vegetation coverages, and water depths and current speeds. Most of the collected snails were Biomphalaria pfeifferi and Bulinus truncatus. The population densities of snails and their infection rates varied across survey sites. The collected snails liberated S. mansoni and S. haematobium cercariae as well as Amphistome and Echinostome cercariae. Infected snails were found during March-June. The ecological characteristics found to be associated with the absence of snails population were: high turbidity, deep water, low vegetation coverage (near absence of vegetation), high water temperature, and high current speed. To our knowledge, this is the first longitudinal study of the snail population and ecological characteristics in the main basin of the White Nile river.

• Journal of the Korea Society of Computer and Information
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• v.26 no.11
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• pp.217-225
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• 2021

In this paper, we designed and implemented the integrated system to prevent adverse drug reactions of polypharmacy components in medicine by supporting component-component information and disease-component information, through data queuing algorithm and vast amounts of pharmaceutical big data. In addition, by providing information for drugs, drug components, prohibited drugs, as well as suppliers and distributors, it could help ease anxiety about taking drugs not only for health-care professionals but also for general users. The representative information provided were side effects between two drugs, main components and effectiveness of particular drugs, drugs manufactured by the same pharmaceutical company, and drug component information for patients with chronic diseases. The future work is to update the database by collecting information on rare & new diseases and new drugs.

• Journal of Korea Water Resources Association
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• v.52 no.1
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• pp.61-70
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• 2019

The modified Kling-Gupta efficiency fusion method to merge actual evapotranspiration was proposed and compared with the simple Taylor skill's score method using Global Land Data Assimilation System (GLDAS), Global Land Evaporation Amsterdam Model (GLEAM), MODIS Global Evapotranspiration Project (MOD16), and the flux tower on three different land cover types over the Korean peninsula and China. In the results of the weights estimated from two actual evapotranspiration merging techniques (i.e., STS and KGF), the weights of reanalysis data (i.e, GLDAS and GLEAM) in cropland and grassland showed similar performance, while the results of weights are different according to the merging techniques in forest. Both two merging techniques showed better results than original dataset in grassland and forest. However, there were no improvement in cropland compared to the other land cover types. The results of the KGF method slightly improved compared to those of the STS in grassland and forest.

• Asia-Pacific Journal of Atmospheric Sciences
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• v.54 no.4
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• pp.599-610
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• 2018

The goal of this study was to statistically analyse the variability of global irradiance and ultraviolet erythemal (UVER) irradiance and their interrelationships with global and UVER irradiance, global clearness indices and ozone. A prediction of short-term UVER solar irradiance values was also obtained. Extreme values of UVER irradiance were included in the data set, as well as a time series of ultraviolet irradiance variability (UIV). The study period was from 2005 to 2014 and approximately 250,000 readings were taken at 5-min intervals. The effect of the clearness indices on global irradiance variability (GIV) and UIV was also recorded and bi-dimensional distributions were used to gather information on the two measured variables. With regard to daily GIV and UIV, it is also shown that for global clearness index ($k_t$) values lower than 0.6 both global and UVER irradiance had greater variability and that UIVon cloud-free days ($k_t$ higher than 0.65) exceeds GIV. To study the dependence between UIVand GIV the ${\chi}^2$ statistical method was used. It can be concluded that there is a 95% probability of a clear dependency between the variabilities. A connection between high $k_t$ (corresponding to cloudless days) and low variabilities was found in the analysis of bidimensional distributions. Extreme values of UVER irradiance were also analyzed and it was possible to calculate the probable future values of UVER irradiance by extrapolating the values of the adjustment curve obtained from the Gumbel distribution.