• 제목/요약/키워드: ginkgo

검색결과 389건 처리시간 0.033초

EGb 761 Protects Cardiac Microvascular Endothelial Cells against Hypoxia/Reoxygenation Injury and Exerts Inhibitory Effect on the ATM Pathway

  • Zhang, Chao;Wang, Deng-Feng;Zhang, Zhuang;Han, Dong;Yang, Kan
    • Journal of Microbiology and Biotechnology
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    • 제27권3호
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    • pp.584-590
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    • 2017
  • Ginkgo biloba extract (EGb 761) has been widely used clinically to reduce myocardial ischemia reperfusion injury (MIRI). Microvascular endothelial cells (MVECs) may be a proper cellular model in vitro for the effect and mechanism study against MIRI. However, the protective effect of EGb 761 on MVECs resisting hypoxia/reoxygenation (H/R) injury is little reported. In this study, H/R-injured MVECs were treated with EGb 761, and then the cell viability, apoptosis, ROS production, SOD activity, caspase-3 activity, and protein level of ATM, ${\gamma}$-H2AX, p53, and Bax were measured. ATM siRNA was transfected to study the changes of protein in the ATM pathway. EGb 761 presented protective effect on H/R-injured MVECs, with decreasing cell death, apoptosis, and ROS, and elevated SOD activity. Next, EGb 761 could inhibit H/R-induced ATM, ${\gamma}$-H2AX, p53, and Bax in a dose-dependent manner. Moreover, ATM siRNA also could inhibit H/R-induced ATM, ${\gamma}$-H2AX, p53, and Bax. Overall, these findings verify that EGb 761 protects cardiac MVECs from H/R injury, and for the first time, illustrate the influence on the ATM pathway and apoptosis by EGb 761 via dampening ROS.

식물체로부터 추출한 물질이 상추 종자의 발아 및 생장에 미치는 영향 (Effects of Water and Ethanol Extracts from Various Plants on the Germination and Growth of Lettuce Seeds)

  • 박건남;이민경;황선주;김학윤;이인중;신동현;김길웅
    • Current Research on Agriculture and Life Sciences
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    • 제17권
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    • pp.1-6
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    • 1999
  • 상추를 포함한 4종의 식물의 수용 및 에탄올 추출액이 상추종자의 발아와 생장에 미치는 영향을 조사한 결과는 다음과 같다. l. 은행, 상추, 돼지풀, 달맞이꽃의 수용 추출물은 상추종자의 발아 및 생장율을 현저하게 억제되는 경향을 보여 억제물질을 함유하고 있음을 알 수 있었다. 2. 추출용매별로는 에탄올 추출액이 수용추출액보다 억제효과가 큰 것으로 나타났다. 3. 공시식물의 종류에 관계없이 추출물의 농도 10%가 상추의 발아와 생장을 가장 크게 억제시켰고 희석되어질수록 그 효과는 낮아졌다.

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Survival of Microorganisms on Antimicrobial Filters and the Removal Efficiency of Bioaerosols in an Environmental Chamber

  • Kim, Sung Yeon;Kim, Misoon;Lee, Sunghee;Lee, JungEun;Ko, GwangPyo
    • Journal of Microbiology and Biotechnology
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    • 제22권9호
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    • pp.1288-1295
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    • 2012
  • Exposure to bioaerosols causes various adverse health effects including infectious and respiratory diseases, and hypersensitivity. Controlling exposure to bioaerosols is important for disease control and prevention. In this study, we evaluated the efficacies of various functional filters coated with antimicrobial chemicals in deactivating representative microorganisms on filters or as bioaerosols. Tested functional filters were coated with different chemicals that included (i) Ginkgo and sumac, (ii) Ag-apatite and guanidine phosphate, (iii) $SiO_2$, ZnO, and $Al_2O_3$, and (iv) zeolite. To evaluate the filters, we used a model ventilation system (1) to evaluate the removal efficiency of bacteria (Escherichia coli and Legionella pneumophila), bacterial spores (Bacillus subtilis spore), and viruses (MS2 bacteriophage) on various functional filters, and (2) to characterize the removal efficiency of these bioaerosols. All experiments were performed at a constant temperature of $25^{\circ}C$ and humidity of 50%. Most bacteria (excluding B. subtilis) rapidly decreased on the functional filter. Therefore, we confirmed that functional filters have antimicrobial effects. Additionally, we evaluated the removal efficiency of various bioaerosols by these filters. We used a six-jet collision nebulizer to generate microbial aerosols and introduced it into the environmental chamber. We then measured the removal efficiency of functional filters with and without a medium-efficiency filter. Most bioaerosol concentrations did not significantly decrease by the functional filter only but decreased by a combination of functional and medium-efficiency filter. In conclusion, functional filters could facilitate biological removal of various bioaerosols, but physical removal of these by functional was minimal. Proper use of chemical-coated filter materials could reduce exposure to these agents.

환경오염 방지를 위한 식물 생태학적 연구(IV) -Cadmium 처리토양에 의한 여러식물의 생장반응- (Ecological Studies of Plants for the Control of Environmental Pollution IV -Growth of Various Plant Species as Influenced by Soil Applied Cadmium-)

  • 차종환
    • Journal of Plant Biology
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    • 제17권4호
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    • pp.23-30
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    • 1974
  • The relations of the growth responses of plants, i.e. 4 species of crops, 12 species of roadside trees and 5 species of horticultural plants to cadmium (Cd) to which added soil were studied in pot culture. Growth in dry weight of corn, soybean, barley and wheat plant were decreased with increase of Cd concentration. Damage of corn plant caused by Cd treatment was more or less recovered when it was grown in soil with calcium, but that of other three crops was not recovered when it was with calcium. Although crop plants used here absorbed small amount of Cd through root, Cd content in the shoot was directly proportionate to the concentration of Cd treated to soil. Additions of calcium and sulfur to soil were effectively to change of soil pH, and only of calcium increased exchangeable calcium and cation exchange capacity of its soil. The chlorosis on leaves caused by Cd treatment was observed in 2 species such as Euonymus japonica and Rhododendron yedoense out of 5 species of the horticultural plants, especially at 50ppm of Cd concentration, Euonymus japonica occurred symptoms of chlorosis and difoliation, and at the higher concentration than that the symtoms were sever more and more. At 200 ppm of Cd feeble damage was observed in Pinus koraiensis and Ginkgo biloba but severe chlorosis observed in Robinia pseudoacacia and Sabina chinensis, Buxus koreana, Abies holophylla and Platanus orientalis. Nevertheless those plants had serious damage at 200 ppm of Cd, such symptom was weakened by adding calcium to soil with Cd. There were many Cd tolerant species out of the plants used in thies xperiment, such as Crassula falcata, Chrysanthemum morfolium, Hibiscus syriacus, Ligustrum ovalifolium, Liriodendron tulipeferia, Lespedeza crytobotrys.

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Characteristic of Soil and Cambial Electrical Resistance for Investigation on Defect Cause of Planting Tree in Apartment

  • Cho, Chi-Woung;Yoo, Sun-Ah;Kim, Jeong-Ho
    • 한국환경과학회지
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    • 제21권11호
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    • pp.1307-1320
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    • 2012
  • The purpose of this paper is to provide information on planting construction for healthy plant growth. To achieve this purpose, this study analyzed the planting type, planting density, withering rate, soil characteristics, and cambium electrical resistance (CER) of withered trees in an apartment complex with a high withering rate. The major plant groups examined consisted of native broad-leaved tree species (39.3%), native narrow-leaved tree species (24.2%), and native broad-leaved - exotic narrow-leaved tree species (16.4%). The planting density of the green area, where trees were planted from 0.0 to 0.3 trees per unit area, was measured as 98.4%. Withered trees were found in 19 of the 20 planted species, and the withering rate was 41.8% (610 withered/1,461 planted). Withering rates for tree species were measured as follows: Sophora japonica and Salix babylonica (100.0%), Magmolia denudata (84.3%), Lindera obtusiloba (74.7%), cornus kousa (69.3%), acer triflorum (69.2%), diospyros kaki (66.7%), Prunus yedoensis (62.8%), Acer palmatum (52.6%), Prunus armeniaca (51.1%), Chaenomeles sinensis (43.7%), Ginkgo biloba (40.9%), Zelkova serrata (31.0%), Cornus officinalis (28.6%), Taxus cuspidata (25.6%), Pinus densiflora (21.4%), Pinus parviflora (15.2%), Pinus strobus (14.6%), and Abies holophylla (10.3%). Soil chemical analyses for 18 samples revealed that as the withering rate increased, the following occurred: (a) the ratio of silt and clay in soil increased; (b) the soil pH, organic matter rate, nitrogen, available phosphorus, and cation exchange capacity (CEC) in samples were graded as "inadequate," based on the plant grading evaluation; and (c) the NaCl and cation exchange capacity were evaluated as "somewhat satisfactory." The measurement of CER for withering rate shows electrical resistance for higher withering rate are higher, which could predict that a tree will not grow well.

THE EFFECTS OF X-RAY IRRADIATION ON THE GERMINATION AND GROWTH OF SEEDLING IN GinKgo biloba L.

  • You, Young-Soo;Kim, Yong-Kwan
    • 한국산림과학회지
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    • 제8권1호
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    • pp.140-148
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    • 1968
  • 우리나라 전체(全體)에 분포(分布) 식재(植栽)되고 있는 은행나무 종자(種字)에 X-선(線)을 조사(照射)하여 발아율(發芽率), 발아장해(發芽障害), 지엽(枝葉)의 형태적변이(形態的變異) 및 초기(初期) 생육(生育)을 조사(調査)한데 대해서 몇가지 결과를 요약(要約)하면 다음과 같다. 1. 대조구(對照區)에 비(比)해서 저선량구(低線量區)(100R)에서는 발아(發芽)가 약간 촉진(促進)되는 경향이 있으나 500R구(區)에서 부터는 현저히 저하(低下)되었으며 2. 발아(發芽)의 $LD_{50}$은 765R으로 추정(推定)된다. 3. 묘장(苗長)에 있어서 저선량구(低線量區)(100R)에서는 감소(減少)의 차이(差異)가 가벼웠으나 타처리구(他處理區)의 감소현상(減少現像)에 대해서는 유의성(有意性)이 인정(認定)되었다. 4. 선량증가(線量增加)에 따라 엽면지수(葉面指數) 거의 직선적(直線的)인 관계(關係)로서 증가(增加)하며 5. T/R율(率)은 반비례적(反比例的)으로 작아졌다. 6. 생체중(生體重)과 건물중(乾物重)에 있어서는 대조구(對照區)에 비(比)해서 100R구(區)에서는 약간 증가(增加)되기도 하나, 250R구(區)에서부터는 감소(減少)되어서 유의성(有意性)이 인정(認定)되었다. 7. 선량(線量)에 따라서 식물체(植物體) 각부분(各部分)에서 다양(多樣)한 형태적(形態的)인 변이(變異)를 볼 수 있었다.

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세계문화유산 잠재지로서 순천 낙안읍성 일원 당산숲의 경관 특성 (Landscape Characteristics of Sacred Dangsan Forests in the Neighborhood of Naganeupseong in Suncheon as a Potential World Heritage Site)

  • 최재웅;김동엽;이창환
    • 농촌지도와개발
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    • 제22권3호
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    • pp.345-354
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    • 2015
  • In this study, the landscape characteristics and culture of the sacred Dangsan forests at Dongnae-ri, Seonae-ri, Namnae-ri, Pyeongchon-ri and Gyochon-ri were investigated. And the potential for registration in the World Heritage List has been discussed by linking the Dangsan forests at the five sites. Dangsan forest, a traditional village forests of rural Korea is a representative cultural heritage with a history of more than several hundred years of Dangsan ritual. The Dangsan forests in the neighborhood of Naganeuoseong have retained the landscape of town fortress during Choseon Dynasty and the Dangsan ritual as a living culture. The three villages inside Naganeuoseong have kept their Upper Dang, Middle Dang and Lower Dang. There were 21 old trees in total; Zelkova serrata (2), Celtis sinensis (7), Aphananthe aspera (5) trees, Carpinus tschonoskii (2) and Ginkgo biloba (3). The three Dangsan trees and an old Aphananthe aspera, known as to be planted by the Admiral Yi Sun-sin were recognized. The two villages located outside of village fortress also have kept their Dangsan ritual. It is important whether the sites possesses authenticity in order to be listed in the World Heritage. The Dangsan forests in the neighborhood of Naganeuoseong have been verified for the authenticity, which should be focused. The places need to be clarified for their landscape features formed as a Dangsan forest, and sustainable protection and management plans are to be devised.

벼멸구에 대한 식물추출물의 살충활성과 기피효과 (Insecticidal Activities and Repellent Effects of Plant Extracts against the Brown Planthopper (Nilaparvata lugens Stäl))

  • 김연국;이종진;최만영
    • 한국응용곤충학회지
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    • 제47권1호
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    • pp.65-74
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    • 2008
  • 식물추출물(20과 35종)을 사용하여 미량국소처리방법과 분무방법으로 벼멸구 암컷성충에 대한 살충활성과 기피효과에 대해 실험을 수행하였다. 살충활성과 기피효과의 결과는 식물종과 그 부위에 따라 다양한 차이를 보였다. 인면과수, 구리광, 미국자리공의 줄기 추출물, 그리고 취춘과 석류나무의 잎+줄기 추출물이 벼멸구에 대하여 높은 살충활성을 보였다. 식물추출물들의 기피효과는 남학슬의 전부위 추출물, 캐슈나무의 열매추출물, 석류나무와 등나무의 잎+줄기 추출물이 높은 기피활성을 보였다. 이 실험에 사용한 식물추출물들에서 기피효과가 높은 식물추출물들의 살충활성이 불규칙적으로 나타나 기피효과와 살충률의 관계가 성립되지 않았다. 따라서 처리된 식물추출물의 벼멸구에 대한 살충활성과 기피 효과는 상관관계가 없음을 알 수 있다.

천연염료 염색포의 생활용품 활용에 관한 연구 (Study on the Utilization of Natural Dyeing Materials as Household Supplies)

  • 주영주
    • 복식
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    • 제56권3호
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    • pp.73-80
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    • 2006
  • This study is aimed to produce natural dyeing garments, which contain the sentiments and color sense of Koreans, by using various household supplies, with a view to increase the values added and utilization of natural dyeing. The dyes mainly used for this study are multi-colored ones which are durable after dyeing and can represent various colors. They include Lithodpermum officinale, Caesalpinia sappan, Rubia Cordifolia, Pellodendron Bak, Curcuma Longa L., fallen Ginkgo Biloba, Artemisia Princeps, and Quereus acutissima carr shell. Considering water pollution and other things, aluminum acetate and ferrous chloride were used as mordants. Cheap and practical materials such as cotton cloth and those with traditional patterns and elegance such as silk and ramie fabrics were used to produce baby goods, household supplies, clothes, and accessories. The produced supplies closely contact with our body, so they may have a great effect on human body. The household supplies produced include rug, bedclothes, room bedclothes, curtain, bedding set, cushion, and sunlight blind, in consideration of the functionality or medical actions of the goods which are closely related to the human skin. The infant supplies produced include longcloth for newborn baby, bedding set, gauze handkerchief, and doll. The clothes include night gown, shirt, bath gown, and Korean traditional clothes. The accessories include tablecloth, cup pad, bag, wrapping cloth, mouse and keyboard cushion, and scarf. Nowadays, consumers prefer environment-friendly naturally dyed garments and products. In order to control the naturally dyed garments and products which are traded in the domestic market, it is urgent to introduce such ecological marks as 'Toxproof' and 'Ecoproof.' Currently, many ordinary persons, who are not experts, have interest and participate in natural dyeing, but they simply produce naturally dyed garments, not artistic works or everyday supplies. The present author expects this study will contribute to the production of household goods by such persons. The author also hopes that they will develop and commercialize such designs as suit to modern tastes and senses based on the unique cultural assets of Koreans, so that Korean naturally dyed products may be recognized as reliable commodities equipped with international competitiveness.

와파린과 상호작용하는 한약재에 대한 고찰 (Overview of the Interaction between Warfarin and Korean Herbal Medicine)

  • 이인;박상무;박승찬;김도형;조민경;한창우;권정남;홍진우
    • 대한한방내과학회지
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    • 제33권2호
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    • pp.160-171
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    • 2012
  • Background and Objective : Warfarin is the standard anticoagulation treatment for atrial fibrillation, venous thromboembolism (VTE), and mechanical heart valves. Close monitoring of the International Normalized Ratio (INR) is required due to the drug's very narrow therapeutic window. Many factors can affect INR levels. Drug and food interactions are frequently cited as causes of adverse events with warfarin. We discussed interactions between herbs and warfarin studied in this research. Methods : In this review, PubMed was used to search medical journals. Keywords "warfarin AND interaction" were applied. Results : 55 articles were included. The possibility of correlation between warfarin and single herbal medicines such as Salviae Miltiorrhizae Radix, Angelicae Gigantis Radix, Ginseng Radix Alba, Lycii Fructus, Ginkgo Folium, Menthae Herba, Trigonellae semen was suggested. Furthermore, some herbal compounds interacting with warfarin were reported. The conclusion of studies reporting the effect of herbal medicine on warfarin were controversial due to small size or quality of research. Conculsions : We suggest that we should prescribe therapeutic herbal medicines to patients using warfarin more carefully and do INR follow-up regularly.