• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.27 no.2
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• pp.135-144
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• 1997

The primary intra-osseous carcinoma (PIOC) is a very rare lesion. PIOC is an odontogenic carcinoma defined as a squamous cell carcinoma arisinig within a jaw having no initial connection with the oral mucosa, and presumably developing from residues of the odontogenic epithelium. The authors diagnosed a 51-year-old female as primary intra-osseous carcinoma after undergoing clinical, radiological and histological examinations. The characteristics were as followed : 1. The patient complained of gingival bleeding on the premolar area in the left maxilla 2. The conventional radiograms showed a relatively well-defined unilocular radiolucent lesion from the mesial aspect of the upper left canine to the mesial aspect of the upper left 1st molar. The 2nd premolar was separated from the 1st molar and the floor of the maxillary sinus was elevated by the lesion. There was a external root resorption of the upper left canine, the 1st premolar, and the 2nd premolar. 3. On the computed tomograms, the osteolytic bony lesion expanded the cortical plate of the left maxilla and displaced the margin of the left maxillary sinus upwards. But the bony lesion was separated from the maxillary sinus by a bony septum. 4. Bone scintigram with /sup 99m/Tc demonstrated the increased uptake in the left maxilla. Sonograms in the neck area and chest P-A radiogram didn't show any abnormalities. 5. Histologically, the tumor islands infiltrating into the surrounding bone increased in alveolar pattern, composed of the malignant cells, and there was a necrosis in the center of the tumor islands.

• The korean journal of orthodontics
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• v.42 no.6
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• pp.307-317
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• 2012

Objective: The purpose of this study was to investigate the isolation and characterization of multipotent human periodontal ligament (PDL) stem cells and to assess their ability to differentiate into bone, cartilage, and adipose tissue. Methods: PDL stem cells were isolated from 7 extracted human premolar teeth. Human PDL cells were expanded in culture, stained using anti-CD29, -CD34, -CD44, and -STRO-1 antibodies, and sorted by fluorescent activated cell sorting (FACS). Gingival fibroblasts (GFs) served as a positive control. PDL stem cells and GFs were cultured using standard conditions conducive for osteogenic, chondrogenic, or adipogenic differentiation. Results: An average of $152.8{\pm}27.6$ colony-forming units was present at day 7 in cultures of PDL stem cells. At day 4, PDL stem cells exhibited a significant increase in proliferation (p < 0.05), reaching nearly double the proliferation rate of GFs. About $5.6{\pm}4.5%$ of cells in human PDL tissues were strongly STRO-1-positive. In osteogenic cultures, calcium nodules were observed by day 21 in PDL stem cells, which showed more intense calcium staining than GF cultures. In adipogenic cultures, both cell populations showed positive Oil Red O staining by day 21. Additionally, in chondrogenic cultures, PDL stem cells expressed collagen type II by day 21. Conclusions: The PDL contains multipotent stem cells that have the potential to differentiate into osteoblasts, chondrocytes, and adipocytes. This adult PDL stem cell population can be utilized as potential sources of PDL in tissue engineering applications.

• Journal of Korean society of Dental Hygiene
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• v.12 no.6
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• pp.1250-1259
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• 2012

Objectives : TThe purpose of this study was to examine the relationship between the oral health education experience of workers and their oral health awareness in an attempt to provide some information on corporate oral health education plans. Methods : The, subjects in this study were 230 workers in Busan and South Gyeongsang Province, on whom a self-administered survey was conducted from August, 2010, to June 18, 2011. A frequency analysis was carried out to grasp the general characteristics of the 205 respondents, and x2-test(p). Results : 1. As for the relationship of the oral health education experience of the workers and their awareness of toothbrush involving optimum toothbrush size, 47.4 percent of those without educational experience thought that a toothbrush should be large enough to cover about two teeth(p<.018). 2. Regarding the relationship between the oral health education experience of the workers and their awareness of fluoride, 59.1 percent of the respondents with educational experience perceived that dentifrice contained fluoride(p<.05). 3. Concerning the relationship between the oral health education experience of the workers and their awareness of periodontal diseases including the cause of the diseases, 43.6 percent of the respondents with educational experience(p<.021). 4. As to the relationship between the oral health education experience of the workers and their awareness of scaling, 50.2 percent of the respondents with educational experience and gingival diseases(p<.037). 5. In terms of the relationship between the oral health education experience of the workers and their awareness of toothbrushing involving toothbrushing frequency, 36.8 percent of those without it considered it necessary to do toothbrushing three times a day(p<.045). Conclusions : The above-mentioned findings illustrated that there were differences among the workers in oral health awareness according to their oral health education experience. Therefore the development of systematic oral health education programs is required to promote the oral health of workers.

• Journal of dental hygiene science
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• v.18 no.1
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• pp.60-68
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• 2018

This study investigates the relationship between smoking and periodontal disease through quantitative analysis of intra-buccal oral pathogenic bacteria detected in smokers and aims to yield objective baseline data for applications in anti-smoking and dental health education programs. From April to May 2016, participants in an oral health management program within an intensive dental hygiene training course at Choonhae College of Health Sciences received an explanation of the study purposes and methods, after which male smokers aged 18~30 years agreed to participate voluntarily. Real-time polymerase chain reaction (PCR) analysis of oral pathogenic bacteria was performed after collecting gingival sulcus fluid samples from 67 smokers. The intra-buccal oral pathogenic bacteria distributions were analyzed based on the subjects' general characteristics, smoking behaviors, and oral care behaviors. The distribution results show that pathogens in the anterior teeth are affected (in this order) by age, toothbrush size, and smoking status; older people had fewer pathogens, those who used larger toothbrushes had more pathogens, and smokers had more pathogens, compared to non-smokers ($_{adj}R^2=19.1$). In the posterior teeth, pathogens were influenced (in this order) by smoking status, smoking duration, and the number of tooth brushings per day; smokers had more pathogens than non-smokers, and those who brushed their teeth more often had fewer pathogens ($_{adj}R^2=25.1$). The overall pathogen distribution was affected only by smoking status: smokers generally had more pathogens, compared to non-smokers. Therefore, it is necessary to provide information about the risk of periodontal disease due to smoking during anti-smoking or dental health education sessions; particularly, the use of smaller toothbrushes for anterior teeth and the need for smokers in their early twenties to quit smoking for dental health should be highly emphasized.

• Journal of Korean society of Dental Hygiene
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• v.9 no.4
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• pp.620-632
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• 2009

Objectives : The present study purposed to survey the oral health-related quality of life among elderly in metropolis Methods : We had individual interviews and oral survey using a questionnaire with 336 elderly who were using seniors' centers in Metropolitan City during the period from the $9^{th}$ to $31^{st}$ of July, 2007. Results : Factors of GOHAI showed the significant relation with types of health insurance, a large number of medication, perceived oral health status, perception of dental care needs those with pains in the temporomandibular joint, the number of natural teeth and the explanatory power or the final model was 25.5%. Factors of OHIP-14 showed the significant relation with types of health insurance, a large number of medication, perception of dental care needs those with pains in the temporomandibular joint, gingival bleeding, the number of natural teeth and the explanatory power or the final model was 26.6%. Conclusions : Oral health-related quality of life among elderly as factors by general characteristics of study subjects, by perceived heath status and oral health status, perceived oral symptoms and oral health status that were relevant. Accordingly, for the healthy maintenance of elders' natural teeth, it is considered necessary to develop and execute continuous oral health management systems and oral health education programs that promote preventive activities and enhance the perception of oral health.

• Journal of Periodontal and Implant Science
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• v.26 no.1
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• pp.317-333
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• 1996

The main goal of periodontal regeneration is to be achieved by epithelial exclusion, periodontal ligament cell activation or alveolar bone regeneration. The purpose of this study was to investigate on the physico- chemical and biological characteristics of biodegradable chitosan beads. Chitosan beads were fabricated by ionic gelation with sodium tripolyphosphate and they had the size in 300um diameter. As therapeutic agent, flurbiprofen was incorporated into the beads by 10, 20% loading contents. The release of drugs from the chitosan beads was measured in vitro. Also, biological activity tests of flurbiprofen loaded chitosan beads including cytotoxicity test, ihhibition of $IL-1{\beta}$ production, suppression to $PGE_2$ production, collagenase inhibition test, the ability of total protein synthesis, and tissue response were evaluated. The amount of flurbiprofen released from chitosan was 33-50% during 7 days. Minimal cytotoxicity was observed in chitosan beads. Flurbiprofen released from chitosan beads significantly suppressed the $IL-1{\beta}$ production of monocyte, $PGE_2$ production and markedly inhibited collagenase activity. Meanwhile, flurbiprofen released from this system showed increased ability for protein synthesis. Throughout 4 -week implantation period, no significant inflammatory cell infiltrated around chitosan bead and also fibroblast like cell types at the beads - tissue interface were revealed with gradual degradation of implanted chitosan beads. From these results, it was suggested that flurbiprofen loaded chitosan beads can be effectively useful for biocompatible local delivery system in periodontal regeneration.

• Journal of Korean society of Dental Hygiene
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• v.14 no.2
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• pp.163-171
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• 2014

Objectives : This study aims to improve health and the quality of life of teenagers by identifying an association between the periodontal status and oral health behaviors of Korean teenagers using 2010 Korean National Oral Health Survey data. Methods : Subjects were teenagers aged from 12 to 15 in Korean National Oral Health Survey (KNOHS). The questionnaire consisted of periodontal status, general characteristics, periodontal related factors, and oral health related behaviors. Results : Gingival bleeding was found in 56.9% of teenagers because unhealthy periodontal status and tartars were found. Those who were 15 years old had unhealthier periodontal status than those who aged 12 years old. Those who lived in rural areas tended to have worse periodontal status than those who lived in the big cities. Access to dental floss, mouth rinsing solution and regular dental checkup tended to make the healthier periodontal status. Smokers had the worse periodontal status than the nonsmokers. Conclusions : The oral health care in the teenagers aged from 12 to 15 is very important because the permanent dentition is completed in this stage. It is necessary to lay emphasis on the oral health improvement and dental caries prevention program to the teenagers.

• Korean Journal of Health Education and Promotion
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• v.26 no.2
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• pp.25-33
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• 2009

Objectives: Smoking is related to periodontal disease and periodontal therapy. So the aim of this study was to investigate the effects of professional tooth cleaning and plaque control instruction (PT & PCI) for smoking behavior. Methods: A total of 151 adults were investigated using the O'Leary Plaque Index (PI), $L\ddot{o}e$ & Silness gingival index (GI) and the number of sextants possessing periodontal pocket (SPP). And adults were given a through dental scaling and Watanabe method for dental plaque control. Follow up examination were conducted after 3 months and compared the pre and post- status. The collected data were analyzed with t-test, paired t-test and one-way analysis of variance. Results: Regardless of smoking behavior, improving effects were identified after PT & PCI on PI, GI and SPP in the whole population. However, the effects of GI improvement were significant in the smoking group alone; those of PI improvement were most significant in the non-smoking group; and those of SPP improvement were more significant in non-smoking and pre-smoking groups than in the smoking group. The shorter period of smoking and the smaller amount of smoking, the greater effects of PT & PCI by smoking-related characteristics. Conclusion: Smoking cessation instruction should necessarily be included in oral health education in that smoking is an important factor to consider in prevention of periodontal diseases and periodontal therapies.

• Journal of the Korea Convergence Society
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• v.11 no.3
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• pp.127-133
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• 2020

This study was to survey the relationship between employment stress and self-rated oral health status in university students from Sep. 2 to 27, 2019. Data were analyzed using the SPSS 22.0 program. In case of high employment stress, the comparative risk of self-rated oral health status was 1.7 times in Gingiva swelling, 1.46 times in ulcer and 1.53 times in hypersensitivity. After correcting the general characteristics (gender, age, grade, major), the comparative risk was 1.56 times for Gingiva swelling, 1.42 times for ulcer and 1.44 times for hypersensitivity. Therefore employment stress was found to be related to oral health and it is considered necessary to find ways to prevent and manage oral health by seeking various methods such as counseling support or stress control to reduce employment stress.

• The Journal of Korean Academy of Prosthodontics
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• v.34 no.3
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• pp.457-463
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• 1996

An esthetically pleasing result in denture service is dependent upon several consideration. Esthetic considerations for the edentulous patient include tooth size, shape, arrangement, positioning, gingival contour, age, sex, personality differences, and ethnic type. Especially, the form of anterior artificial teeth is an important factor on the esthetics. The selection of artificaial teeth requires understanding and knowledge on physical and biologic factors and has to meet the indivisul esthetics and functional needs of each patient. However, the selection of artificial teeth is based on the large degree of subjective judgement of the dentist, Therefore, this is one of the most unscientific processes. Many attempts have been made to find a guideline for the selection of artificial teeth. Temperamental theory by White and Hall utillized with the physical characteristics such as body size, body form, color of eyes and hair, and disposition. SPA theory by Frush and Fisher utilized with the basis of sex, personalities, and age of the indivisual. There has not been provided for a guideline and study on the selection of artificial teeth for Koreans yet. This study was aimed to evaluate the William's typal matching theory in Koreans. 1. The facial forms of korean adult were ovoid(46.3%), square(36.7%) and tapered(17.0%) form. 2. The anatomic forms of natural maxillary incisors were ovoid(45.3%), tapered(31.3%), square(23.3%) form. 3. The forms of face and natural maxillary incisors were ovoid(21.9%), squared(11%), tapered(6.3%). 4. The natural maxillary incisors were similar in form to the facial form only in 39%. There was no correlation between the form of the face and the form of natural maxillary central inisors in Koreans. 5. Artificaial teeth which was selected according to the typal matching theory did not represent the form of the natural teeth in 61 per cents of the fatal, but it felt that they harmonized with the form of the patient's face and produced good results.