• Journal of Acupuncture Research
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• 제27권6호
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• pp.115-122
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• 2010

Objectives : The purpose of this study was to propose the utilization plan of Ryodoraku in the U-health care systems. Methods : Computerized literature searches were performed for Ryodoraku related articles using the following databases: KISS, RISS, DBPIA, NDSL from 1990 to Oct 2010. Search terms were '양도락' or 'Ryodoraku' or 'U-health'. Due to Ryodoraku coming from Japan, additional literature review(articles published by 2008) on Japanese journal of Ryodoraku medicine was done for compensation. Results : 1. Introduction of U-health : As rapid progress of population aging and strong interest in health, the demand for the traditional Korean medical service is increasing. Until now healthcare service has provided post treatment by face-to-face manner. But according to related researches, proactive treatment is resulted to be more effective for preventing diseases. Particularly, the existing healthcare services have limitations in preventing and managing chronic geriatric degenrative diseases such as metabolic syndrome, CVA, coronary heart diseases, parkinson's diseases, degenerative joint disease, spondylosis, etc., because the cause of the above is complex and even related to life habit. As the advent of ubiquitous technology, patients with the chronic geriatric degenrative diseases can improve life habit such as poor eating habits and physical inactivity without the constraints of time and space through u-healthcare service. Therefor, lots of researches for u-healthcare service focus on providing the personalized healthcare service for preventing and managing that. To cope with this situations, The concept of u-healthcare service should be adopted in the traditional korean medicine and diagnostic devices suitable for it should be also devised and developed based on traditonal korean medine. 2. Review of existing Ryodoraku related articles for applying to U-health : articles investigating feasibility applying Ryodoraku to meridian diagnosis and raising problems of it, articles providing recent research trends of Ryodoraku, Ryodoraku related articles considering usefulness for U-health, and articles confirming the repeatability and reproducity of Ryodoraku were included. Based on the review of the above Ryodoraku related articles, several application of Ryodoraku in the U-health care system. Conclusions : To make preparations for the increasing need of traditional Korean medicine due to rising morbidity rate of chronic geriatric degenerative diseases, it is necessary to appropriately apply Ryodoraku to the U-health care system. The application of Ryodoraku is as follows. 1. To use Ryodoraku additionally to the established diagnostic device of metabolic syndrome, CVA, coronary heart diseases, parkinson's diseases, degenerative joint disease, spondylosis. 2. To apply Ryodoraku to the symptoms or diseases having a tendency to be diagnosed by correlation between the affected meridian and the lesion such as headache, nuchal pain, shoulder pain, low back pain, sciatica, HNP, etc. 3. To secure the repeatability and reproducity of Ryodoraku. 4. To devise and develop Ryodoraku appliance in order to overcome the known drawbacks and to improve error of measurement.

• 디지털융복합연구
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• 제11권1호
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• pp.431-439
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• 2013

본 연구는 성인병 질환자 및 정상 노인을 대상으로 적정 강도의 유산소 운동 근력운동을 병행한 복합운동 프로그램을 24주간 실시한 후 신체구성, 혈액성분, 체력의 변화가 운동 전 후 어떠한 차이를 나타내는지 비교하고 성인병 질환자들을 위한 가장 효과적인 복합운동 프로그램을 작성하는데 목적이 있다. 이를 위하여 K도시에 거주하는 만 65세 이상의 성인병 질환자 20명과 정상노인 20명을 선정하여 이들에게 24주간의 복합 운동을 규칙적으로 실시하도록 하였다. 연구 결과로 신체구성의 변화는 성인병 집단의 경우 모두 유의하게 증가하였으나 정상인 집단은 복부지방률만 유의하게 나타났다. 혈액성분의 변화는 정상군에서 근소한 차이로 향상되는 결과를 보였으나, 유질환군과 근소한 차이를 보여 프로그램 전 후 상호작용은 유의한 차이가 없다. 프로그램 실시 전 후 근력, 각근력, 민첩성, 근지구력, 평형성에 있어 유의한 차이를 보이며 두 집단 모두 체력의 긍정적 향상 결과를 보였다. 정상인 집단에서는 건강을 유지하고 체력향상에 효과적이었고 성인병 집단에서는 질환의 예방과 악화 방지에 긍정적 요소가 나타났다고 볼 수 있다. 더불어 전 노인 인구의 50% 이상이 한 가지 이상의 성인병 질환을 가지고 있으면서도 운동의 참여도가 현저히 저하되는 현실 속에서 적극적인 운동 프로그램을 개발하여 복합운동 프로그램을 실시한다면 건강증진은 물론 삶의 질적 향상에 도움이 될 것이고 차후 보다 많은 연구가 필요할 것이라 사료 된다.

• 대한치과의사협회지
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• 제49권10호
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• pp.584-598
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• 2011

The age structure has been experiencing substantial change due to the decreased birth rate as well as the increased life expectancy. Gorge Magnus, an English economist, casts warnings of population ageing which has the potential of huge socioeconomic impact human society has never experienced before. The prediction that proportion of elderly people in need of oral health care will increase substantially is a new challenge to dentists in the future. The old paradigm that the aged person is just the person who was born earlier and needs the same conventional oral health care should be shifted to the new one. Elderly people tend to express their political interest related with health care system by actively participating in the national elections. The need to sustain economic status for the extended life span makes them seek eagerly esthetic health care to maintain sound social function. Most of them are under multiple chronic diseases and take related medicines. In addition, many studies report about mental change as well as physical change among the aged people. Since the prevalence of dental diseases among the aged is higher than other chronic devastating diseases, the aged seeking oral health care will increase. The aged who has different physical and psychological status as well as chronic disease and related medicine will show unexpected response to the conventional oral health care. In addition, the impact of tooth loss is substantial physically, mentally and emotionally. Dentist should prepare different approaches for the elderly dental patient.

• Journal of Korean Neurosurgical Society
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• 제51권6호
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• pp.350-358
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• 2012

Objective : Life expectancy for humans has increased dramatically and with this there has been a considerable increase in the number of patients suffering from lumbar spine disease. Symptomatic lumbar spinal disease should be treated, even in the elderly, and surgical procedures such as fusion surgery are needed for moderate to severe lumbar spinal disease. However, various perioperative complications are associated with fusion surgery. The aim of this study was to examine perioperative complications and assess risk factors associated with lumbar spinal fusion, focusing on geriatric patients at least 70 years of age in the Republic of Korea. Methods : We retrospectively investigated 489 patients with various lumbar spinal diseases who underwent lumbar spinal fusion surgery between 2003 and 2007 at our institution. Three fusion procedures and the number of fused segments were analyzed in this study. Chronic diseases were also evaluated. Risk factors for complications and their association with age were analyzed. Results : In this study, 74 patients experienced complications (15%). The rate of perioperative complications was significantly higher in patients 70 years of age or older than in other age groups (univariate analysis, p=0.001; multivariate analysis, p=0.004). However, perioperative complications were not significantly associated with the other factors tested (sex, comorbidities, operation procedures, fusion segments involved). Conclusion : Increasing age was an important risk factor for perioperative complications in patients undergoing lumbar spinal fusion surgery whereas other factors were not significant. We recommend good clinical judgment and careful selection of geriatric patients undergoing lumbar spinal fusion surgery.

• 한국실내디자인학회논문집
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• 제13권5호
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• pp.143-153
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• 2004

This research aimed to assess nursing homes for the elderly with geriatric diseases in Japan, and to prepare the knowledge basis to develop nursing home for the elderly with geriatric diseases in Korea. For this, researcher visited 5 facilities in Tokyo from October 3 to October 9 in 2002, collected data by observations, interviews, and visual materials by taking photographs. Visual materials were analyzed according to the environmental assessment matrix consisted of supportiveness, flexibility, efficiency in perception, accessibility, safety, amenity, and social Interaction that were assorted and were given a name by these researchers in the process of this research. Among the characteristics of environmental design of the analysis cases, 992 items picked out from 722 visual materials were used in the analysis. The data were analyzed using the frequency and percentage with SPSS 11 program. The analysis results were the fellowing. The characteristics of recent nursing home design in Japan tended to focus on supportiveness, amenity, and efficiency in perception but to leave much desired in flexibility and safety. In each space, space to support outdoor activities tended to focus on efficiency in perception, space to support living activities tended to focus on amenities, space to support treatment and living tended to focus on supportiveness, space to support administration and operation tended to focus on supportiveness, and space to support movement tended to focus on amenities.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제5권9호
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• pp.7-16
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• 1999

The purpose of this study was to propose and estimate the architectural planning of general hospital in Korea, for the aged society in the near future. Average life expectancy of Koreans has been lengthened and the percentage of the aged populations is expected to be increased sharply. Therefore, the social problems for the aged occur in various levels, especially in healthcare facilities and medical system due to the weak health conditions of the aged. These problems will become more serious in the near future. However, the architectural planning of general hospital in Korea has not been prepared for the aged society yet. The results of this study were as follows the ward of general hospital should be divided into acute and geriatric wards because of the characteristics of geriatric diseases.

• 대한치과의사협회지
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• 제56권5호
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• pp.287-295
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• 2018

Eating-swallowing disorder (dysphagia) is a very important functional problem for the elderly, and it has a significant impact on the quality of their life. Because the eating and swallowing processes are affected by oral tissues including teeth, tongue, and oral muscles, it is natural that the dentist as a specialist in oro-facial region, intervenes in the diagnosis and treatment of the disorder. Nevertheless, Korean dentists still lack interest and understanding of dysphagia. In aged society, it is necessary that the dentists understand the functional disorders as well as oral diseases. The purpose of this study is to introduce the evaluation and treatment methods of eating and swallowing functional disorders in order to cope with eating-swallowing disordered patients who are frequently encountered in aged society.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2643-2648
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• 2016

Background: High-sensitivity C-reactive protein (hsCRP) levels are lower in Japanese compared with Western subjects. Since it is uncertain whether hsCRP is a potent predictor of mortality at low CRP concentrations, the present study examined associations with all-cause and cause-specific mortality in a large population of Japanese. Materials and Methods: Subjects were 4,737 men and 6,343 women aged 49-76 years participating in the baseline survey of an ongoing cohort study of lifestyle-related diseases between February 2004 and July 2006. Hazard ratios for all-cause and cause-specific mortality associated with hsCRP levels were estimated using Cox proportional hazards regression. Results: A total of 436 all-cause deaths occurred during a median follow-up of 8 years. The main cause of death was cancer. In men, hsCRP levels were positively associated with the risk of all-cause mortality as well as deaths from cancer and cardiovascular disease (CVD). All-cause mortality hazards for the 2nd (0.34-0.84 mg/L) and the 3rd (${\geq}0.85mg/L$) tertiles of hsCRP were 1.27 (95% confidence interval [CI], 0.93-1.73) and 1.75 (1.30-2.37), respectively (p for trend=0.001). In women, increased risk of all-cause and cause-specific mortality associated with elevated hsCRP levels was observed, but the associations were not statistically significant. Conclusions: HsCRP may be an independent predictor of all-cause, cancer and CVD mortality in apparently healthy Japanese men, but not women. The differential effect of hsCRP in predicting mortality risk by sex warrants further investigation.

• 한국응용과학기술학회지
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• 제35권4호
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• pp.1456-1471
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• 2018

이 논문은 노령견이 필요한 영양을 다루며, 노령견이 필요로 하는 영양평가를 검토하고, 노령화와 관련하여 흔히 발생할 수 있는 영양의 문제점들을 등을 제시하고자 한다. 즉, 이연구의 목표는 노령견의 노령화와 관련된 생리적인 변화, 필수영양소 및 그와 관련된 질병을 탐구하는데 있다. 2002년의 조사에 의하면, 미국에서 기르는 반려견의 30%-40%는 나이가 7세이상이라고 한다. 유렵의 경우 1983년과 1995년을 비교했을 때 나이가 7세이상의 반려견의 수는 약 50% 늘었다고 한다. 2012에 미국에서 실시한 이메일 조사에 의하면, 50,347명의 응답자 중에서 33.2%가 6살-10살의 노령견을 기르고 있으며, 11살이상의 노령견을 기르는 응답자는 14.7%라고 한다. 가정에서 기르는 반려견의 평균수명은 건강관리, 노령화 및 영양에 영향을 받는다. 그리고 견종, 유전, 영양, 환경 등의 요소에 따라서 노령화의 정도가 다르다. 10살이 넘은 많은 반려견들이 활력이 넘치고 건강하다고 할지라도, 대부분의 반려견들은 5세-6세가 되면, 노령화와 관련된 징조를 보이기 시작한다. 여러가지 질병을 치유할 수 있는 의학의 발달과 영양의 발달로 인하여, 반려견의 평균수명은 점점 증가하고 있다. '노령견을 위한 영양의 목표'는 노령견이 건강하고 활력 넘치게 하며, 노령과 관련된 건강상의 문제가 늦게 시작되고, 노령화를 지연시키며, 삶의 질을 향상시키며, 기대수명을 늘리는데 있다. 노령화는 생리적인 변화를 가져온다. 우리가 육안으로 명백하게 느낄 수 있는 변화들은 털의 색깔이 하얗게 변하는 것, 몸의 기력이 떨어는 것, 시각이나 청각 등의 감각기관에 문제가 오는 것 등이 있으며, 표면적으로 느끼기 어려운 변화들은 소화관, 면역시스템, 신장 등 장기와 관련된 생리적인 변화들이다. 반려견이 필요로 하는 영양은 나이에 따라서 다르다. 또한 노령화가 진행됨에 따라서 발생할 수 있는 영양과 관련된 많은 질병들이 있으며, 이러한 질병에는 영양이 매우 중요하다.

• Biomolecules & Therapeutics
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• 제17권1호
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• pp.70-78
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• 2009

Coptis japonica (C. japonica) is a perennial medicinal plant that has anti-inflammatory activity. C. japonica contains numerous biologically active alkaloids including berberine, palmatine, epi-berberine, and coptisine. The most well-known anti-inflammatory principal in C. japonica is berberine. For example, berberine has been implicated in the inhibition of iNOS induction by cytokines in microglial cells. However, the efficacies of other alkaloids components on microglial activation were not investigated yet. In this study, we investigated the effects of three alkaloids (palmatine, epi-berberine and coptisine) from C. japonica on lipopolysaccharide (LPS)-induced microglial activation. BV2 microglial cells were immunostimulated with LPS and then the production of several inflammatory mediators such as nitric oxide (NO), reactive oxygen species (ROS) and matrix metalloproteinase-9 (MMP-9) were examined as well as the phosphorylation status of Erk1/2 mitogen activated protein kinase (MAPK). Palmatine and to a lesser extent epi-berberine and coptisine, significantly reduced the release of NO, which was mediated by the inhibition of LPS-stimulated mRNA and protein induction of inducible nitric oxide synthase (iNOS) from BV2 microglia. In addition to NO, palmatine inhibited MMP-9 enzymatic activity and mRNA induction by LPS. Palmatine also inhibited the increase in the LPS-induced MMP-9 promoter activity determined by MMP-9 promoter luciferase reporter assay. LPS stimulation increased Erk1/2 phosphorylation in BV2 cells and these alkaloids inhibited the LPS-induced phosphorylation of Erk1/2. The anti-inflammatory effect of palmatine in LPS-stimulated microglia may suggest the potential use of the alkaloids in the modulation of neuroinflammatory responses, which might be important in the pathophysiological events of several neurological diseases including Alzheimer's disease (AD), multiple sclerosis (MS), Parkinson's disease (PD) and stroke.