• Title/Summary/Keyword: genetic structure

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Indigenous Thai Beef Cattle Breeding Scheme Incorporating Indirect Measures of Adaptation: Sensitivity to Changes in Heritabilities of and Genetic Correlations between Adaptation Traits

  • Kahi, A.K.;Graser, H.U.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.8
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    • pp.1039-1046
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    • 2004
  • A model Indigenous Thai beef cattle breeding structure consisting of nucleus, multiplier and commercial units was used to evaluate the effect of changes in heritabilities of and genetic correlations between adaptation traits on genetic gain and profitability. A breeding objective that incorporated adaptation was considered. Two scenarios for improving both the production and the adaptation of animals where also compared in terms of their genetic and economic efficiency. A base scenario was modelled where selection is for production traits and adaptation is assumed to be under the forces of natural selection. The second scenario (+Adaptation) included all the information available for base scenario with the addition of indirect measures of adaptation. These measures included tick count (TICK), faecal egg count (FEC) and rectal temperature (RECT). Therefore, the main difference between these scenarios was seen in the records available for use as selection criteria and hence the level of investments. Additional genetic gain and profitability was generated through incorporating indirect measures of adaptation as criteria measured in the breeding program. Unsurprisingly, the results were sensitive to the changes in heritabilities and genetic correlations between adaptation traits. However, there were more changes in the genetic gain and profitability of the breeding program when the genetic correlations of adaptation and its indirect measures were varied than when the correlations between these measures were. The changes in the magnitudes of the genetic gain and profit per cow stresses the importance of using reliable estimates of these traits in any breeding program.

Genetic Variation and Phylogenetic Relationships of Indian Buffaloes of Uttar Pradesh

  • Joshi, Jyoti;Salar, R.K.;Banerjee, Priyanka;Upasna, S.;Tantia, M.S.;Vijh, R.K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.9
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    • pp.1229-1236
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    • 2013
  • India possesses a total buffalo population of 105 million out of which 26.1% inhabit Uttar Pradesh. The buffalo of Uttar Pradesh are described as nondescript or local buffaloes. Currently, there is no report about the genetic diversity, phylogenetic relationship and matrilineal genetic structure of these buffaloes. To determine the origin and genetic diversity of UP buffaloes, we sequenced and analysed the mitochondrial DNA D-loop sequences in 259 samples from entire Uttar Pradesh. One hundred nine haplotypes were identified in UP buffaloes that were defined by 96 polymorphic sites. We implemented neutrality tests to assess signatures of recent historical demographic events like Tajima's D test and Fu's Fs test. The phylogenetic studies revealed that there was no geographic differentiation and UP buffaloes had a single maternal lineage while buffaloes of Eastern UP were distinctive from rest of the UP buffaloes.

Genetic diversity and population structure in five Inner Mongolia cashmere goat populations using whole-genome genotyping

  • Tao Zhang;Zhiying Wang;Yaming Li;Bohan Zhou;Yifan Liu;Jinquan Li;Ruijun Wang;Qi Lv;Chun Li;Yanjun Zhang;Rui Su
    • Animal Bioscience
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    • v.37 no.7
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    • pp.1168-1176
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    • 2024
  • Objective: As a charismatic species, cashmere goats have rich genetic resources. In the Inner Mongolia Autonomous Region, there are three cashmere goat varieties named and approved by the state. These goats are renowned for their high cashmere production and superior cashmere quality. Therefore, it is vitally important to protect their genetic resources as they will serve as breeding material for developing new varieties in the future. Methods: Three breeds including Inner Mongolia cashmere goats (IMCG), Hanshan White cashmere goats (HS), and Ujimqin white cashmere goats (WZMQ) were studied. IMCG were of three types: Aerbas (AEBS), Erlangshan (ELS), and Alashan (ALS). Nine DNA samples were collected for each population, and they were genomically re-sequenced to obtain high-depth data. The genetic diversity parameters of each population were estimated to determine selection intensity. Principal component analysis, phylogenetic tree construction and genetic differentiation parameter estimation were performed to determine genetic relationships among populations. Results: Samples from the 45 individuals from the five goat populations were sequenced, and 30,601,671 raw single nucleotide polymorphisms (SNPs) obtained. Then, variant calling was conducted using the reference genome, and 17,214,526 SNPs were retained after quality control. Individual sequencing depth of individuals ranged from 21.13× to 46.18×, with an average of 28.5×. In the AEBS, locus polymorphism (79.28) and expected heterozygosity (0.2554) proportions were the lowest, and the homologous consistency ratio (0.1021) and average inbreeding coefficient (0.1348) were the highest, indicating that this population had strong selection intensity. Conversely, ALS and WZMQ selection intensity was relatively low. Genetic distance between HS and the other four populations was relatively high, and genetic exchange existed among the other four populations. Conclusion: The Inner Mongolia cashmere goat (AEBS type) population has a relatively high selection intensity and a low genetic diversity. The IMCG (ALS type) and WZMQ populations had relatively low selection intensity and high genetic diversity. The genetic distance between HS and the other four populations was relatively high, with a moderate degree of differentiation. Overall, these genetic variations provide a solid foundation for resource identification of Inner Mongolia Autonomous Region cashmere goats in the future.

An Optimization of Polynomial Neural Networks using Genetic Algorithm

  • Kim, Dong-Won;Park, Jang-Hyun;Huh, Sung-Hoe;Yoon, Pil-Sang;Park, Gwi-Tae
    • 제어로봇시스템학회:학술대회논문집
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    • 2002.10a
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    • pp.61.3-61
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    • 2002
  • $\textbullet$ Abstract $\textbullet$ Introduction $\textbullet$ Genetic Algorithm $\textbullet$ Evolutionary structure optimization of PNN $\textbullet$ Simulation result $\textbullet$ Conclusion $\textbullet$ References

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Designing Neural Network Using Genetic Algorithm (유전자 알고리즘을 이용한 신경망 설계)

  • Park, Jeong-Sun
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.9
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    • pp.2309-2314
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    • 1997
  • The study introduces a neural network to predict the bankruptcy of insurance companies. As a method to optimize the network, a genetic algorithm suggests optimal structure and network parameters. The neural network designed by genetic algorithm is compared with discriminant analysis, logistic regression, ID3, and CART. The robust neural network model shows the best performance among those models compared.

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Handwritten Digit Recognition with Softcomputing Techniques

  • Cho, Sung-Bae
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 1998.06a
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    • pp.707-712
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    • 1998
  • This paper presents several softcomputing techniques such as neural networks, fuzzy logic and genetic algorithms : Neural networks as brain metaphor provide fundamental structure, fuzzy logic gives a possibility to utilize top-down knowledge from designer, and genetic algorithms as evolution metaphor determine several system parameters with the process of bottom up development. With these techniques, we develop a pattern recognizer which consists of multiple neural networks aggregated by fuzzy integral in which genetic algorithms determine the fuzzy density values. The experimental results with the problem of recognizing totally unconstrained handwritten numeral show that the performance of the proposed method is superior to that of conventional methods.

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Implementation and Diversity Analysis of Tree Structure based Genetic Operators in GP (트리구조 기반 GP 연산자의 구현 및 다양성 분석)

  • Pang, Cheul-Hyuk;Seo, Ki-Sung
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2008.04a
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    • pp.294-298
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    • 2008
  • 이메본 논문은 GP 트리의 노드포화도를 제어함으로써 트리의 구조공간에서 효율적인 개체 분포를 유도하는 GP 진화연산자를 제안한다. 특정 영역으로의 트리 개체의 분포가 성능에 미치는 영향을 검증하고 진화과정에서 나타나는 군집내의 개체 다양성과의 관계를 분석한다. 제안된 진화연산자를 회귀다항식, 멀티플렉서, 짝수 패리티의 3가지 벤치마크 문제에 대해서 실험을 하였고, 표준 GP 연산자와 비교하였다.

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Optimal Design of Dielectric-loaded Surface Plasmon Polariton Waveguide with Genetic Algorithm

  • Jung, Jae-Hoon
    • Journal of the Optical Society of Korea
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    • v.14 no.3
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    • pp.277-281
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    • 2010
  • We propose a design and optimization method for a dielectric-loaded surface plasmon polariton waveguide using a genetic algorithm. This structure consists of a polymer ridge on top of two layers of substrate and gold film. The thickness, width and refractive index of the ridge are designed to optimize the figures of merit including mode confinement and propagation length. The modal analysis combined with the effective index method shows that the designed waveguide exhibits a fundamental propagation mode with high mode confinement while ensuring that the propagation loss remains relatively low.

EXAMINATION OF TYR-264 FOR ATPase ACTIVE SITE IN E.coli RecA PROTEIN BY SITE-DIRECTED MUTAGENESIS

  • Kwon, Yong-Kook;Bae, Jun-Seong;Hahn, Tae-Ryong
    • Journal of Photoscience
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    • v.2 no.1
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    • pp.27-29
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    • 1995
  • Site directed mutagenesis has been introduced to determine active site(s) and molecular structure of E. coli RecA protein. Recombinant DNAs were constructed by point mutation of Tyr-264 to Phe which assumed active site for binding and hydrolysis of ATP. RecA proteins were purified from recombinants containing wild type and mutant genes and analyzed for ATPase activity assay. Result suggests that Tyr-264 is involved in ATP binding rather than ATP hydrolysis.

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A Structural Learning of MLP Classifiers Using PfSGA (PfSGA를 이용한 MLP 분류기의 구조 학습)

  • 愼晟孝;金 商雲
    • Proceedings of the IEEK Conference
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    • 1998.10a
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    • pp.1277-1280
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    • 1998
  • We propose a structural learning method of MLP classifiers for a given application using PfSGA (parameter-free species genetic algorithm), which is a combining of species genetic algorithm(SGA) and parameter-free genetic algorithm(PfGA). experimental results show that PfSGA can reduce the learing time of SGA and has no influence of parameter values on structural learning. And we also convince that PfSGA is more efficient than the other methods in the aspect of misclassification ratio, learning rate, and complexity of MLP structure.

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