• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.4143-4147
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• 2016

Purpose: We evaluated all PET/CTs acquired for patients without a primary diagnosis of colorectal cancer, and compared results for those who had subsequent colonoscopy within 6 months, to assess the accuracy of FDG PET/CT for detection of incidental pre-malignant polyps and malignant colon cancers. Materials and Methods: Medical records of 9,545 patients who underwent F-18 FDG PET/CT studies over 3.5 years were retrospectively reviewed. Due to pre-existing diagnosis of colorectal cancer, 818 patients were excluded. Of the remainder, 157 patients had colonoscopy within 6 months (79 males; mean age 61). We divided the colon into 4 regions and compared PET/CT results for each region with colonoscopy and histopathologic findings. True positive lesions included colorectal cancer, villous adenoma, tubulovillous adenoma, tubular adenoma and serrated hyperplastic polyp/hyperplastic polyposis. Results: Of 157 patients, 44 had incidental colonic uptake on PET/CT (28%). Of those, 25 had true positive (TP) uptake, yielding a 48% positive predictive value (PPV); 9% (4/44) were adenocarcinoma. There were 23 false positive (FP) lesions of which 4 were hyperplastic polyp, one was juvenile polyp and 7 were explained by diverticulitis. Fifty eight patients had false negative PET scans but colonoscopy revealed true pre-malignant and malignant pathology, yielding 23% sensitivity. The specificity, negiative predictive value (NPV) and accuracy were 96%, 90% and 87%, respectively. The average SUVmax values of TP, FP and FN lesions were 7.25, 6.11 and 2.76, respectively. There were no significant difference between SUVmax of TP lesions and FP lesions (p>0.95) but significantly higher than in FN lesions (p<0.001). The average size (by histopathology and colonoscopy) of TP lesions was 18.1 mm, statistically different from that of FN lesions which was 5.9 mm (p<0.001). Fifty-one percent of FN lesions were smaller than 5 mm (29/57) and 88% smaller than 10 mm (50/57). Conclusions: The high positive predictive value of incidental focal colonic FDG uptake of 48% for colonic neoplasia suggests that colonoscopy follow-up is warranted with this finding. We observed a low sensitivity of standardly acquired FDG-PET/CT for detecting small polyps, especially those less than 5 mm. Clinician and radiologists should be aware of the high PPV of focal colonic uptake reflecting pre-malignant and malignant lesions, and the need for appropriate follow up.

• Journal of Korean Society of Steel Construction
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• v.26 no.3
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• pp.231-240
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• 2014

The T-stub subjected to an axial tensile force shows various behavior characteristics according to the changes in the diameter and tightening force of the fastener, the geometric shape of the T-stub, and the material properties of the T-stub and fastener. Due to the influence of these changes, the T-stub shows three failure modes: plastic failure after the flexural yielding of the T-stub flange, flexural yielding of the T-stub fillet, and fracture of the fastener. In general, a T-stub with a thin flange and where the gauge distance of the fastener is long has a larger energy dissipation capacity than a T-stub with a thick flange and where the gauge distance of the fastener is short, due to the plastic deformation after flexural yielding. In this study, three-dimensional nonlinear finite element analysis was carried out to determine the effect of the fastener used for fastening the T-stub on the energy dissipation capacity of the T-stub. For the fastener of the T-stub analysis model, F10T-M20 high-tension bolts and ${\varnothing}19.05-mm$ (3/4-inch) SMA bars were modeled, and the geometric shape of the T-stub was selected to represent the flexural yielding of the T-stub fillet and the axial tensile failure of the fastener.

• Journal of the Korea Concrete Institute
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• v.24 no.3
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• pp.259-266
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• 2012

A general earthquake resistant design philosophy of ductile frame buildings allows beams to form plastic hinges adjacent to beam-column connections. In order to carry out this design philosophy, the ultimate bond or shear strength of the beam should be greater than the flexural yielding force and should not degrade before reaching its required ductility. The behavior of RC members dominated by bond or shear action reveals a dramatic reduction of energy dissipation in the hysteretic response due to the severe pinching effects. In this study, a method was proposed to predict the deformability of reinforced concrete members with short-span-to-depth-ratios, which would result in bond failure after flexural yielding. Repeated or cyclic loading produces a progressive deterioration of bond that may lead to failure at lower cyclic bond stress levels. Accumulation of bond damage is caused by the propagation of micro-cracks and progressive crushing of concrete in front of the lugs. The proposed method takes into account bond deterioration due to the degradation of concrete in the post yield range. In order to verify bond deformability of the proposed method, the predicted results were compared with the experimental results of RC members reported in the technical literature. Comparisons between the observed and calculated bond deformability of the tested RC members showed reasonably good agreement.

• Archives of Plastic Surgery
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• v.32 no.2
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• pp.219-226
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• 2005

Muller's muscle-levator aponeurosis advancement procedure was performed to correct mild to moderate congenital blepharoptosis with moderate to good levator function and to correct severe aquired blepharoptosis with poor levator function. Through the blepharoplasty incision, the upper half of the tarsal plate was exposed and the orbital septum was opened to show the levator aponeurosis. The Muller's muscle was dissected from the superior margin of the tarsal plate and from the posteriorly located conjunctiva with sharp scissors. The Muller's muscle and levator aponeurosis were advanced on the anterior surface of the tarsal plate as a composite flap and fixed approximately 3 to 4 mm inferior to the upper edge of the tarsal plate with three horizontal 6-0 nylon mattress sutures. The amount of advancement of the composite flap was controlled by the location of the upper eyelid margin 2 mm below the upper limbus in primary gaze after the first suture in the middle portion of the flap. The excess flap was trimmed off with scissors, but trimming was usually not necessary in cases of mild to moderate ptosis. Nine cases underwent this Muller's muscle-levator aponeurosis advancement procedure from September 2003 to September 2004. Five cases were congenital blepharoptosis with 2-4 mm ptosis and more than 5 mm of levator function, but three of the four acquired ptosis cases had more than 4 mm ptosis with poor levator function. The age of the patients ranged from 7 to 81 years. In operative results, all patients except one traumatic case were within 1 mm of the desired eyelid height in primary gaze. This procedure can provide not only tightening of the Muller's muscle but also advancement and firm fixation of the levator aponeurosis to the tarsal plate, yielding predictable results.

• Structural Monitoring and Maintenance
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• v.5 no.2
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• pp.205-229
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• 2018

Energy induced by minor earthquake and micro vibration cannot be dissipated by traditional buckling-restrained braces (BRBs). To solve this problem, a new type of hybrid passive control device, named as VE-BRB, which is configured by a BRB with high-damping viscoelastic (VE) layers, is developed and studied. Theoretical analysis, performance tests, numerical simulation and case analysis are conducted to study the seismic behavior of VE-BRBs. The results indicate that the combination of hysteretic and damping devices lead to a multi-phased nature and good performance. VE-BRB's working state can be divided into three phases: before yielding of the steel core, VE layers provide sufficient damping ratio to mitigate minor vibrations; after yielding of the steel core, the steel's hysteretic deformations provide supplemental dissipative capacity for structures; after rupture of the steel core, VE layers are still able to work normally and provide multiple security assurance for structures. The simulation results agreed well with the experimental results, validating the finite element analysis method, constitutive models and the identified parameters. The comparison of the time history analysis on a 6-story frame with VE-BRBs and BRBs verified the advantages of VE-BRB for seismic protection of structures compared with traditional BRB. In general, VE-BRB had the potential to provide better control effect on structural displacement and shear in all stages than BRB as expected.

• Structural Engineering and Mechanics
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• v.47 no.6
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• pp.881-898
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• 2013

This paper describes analytical investigation into a new dual function system including a couple of shear links which are connected in series using chevron bracing capable to correlate its performance with magnitude of earthquakes. In this proposed system, called Chevron Knee-Vertical Link Beam braced system (CK-VLB), the inherent hysteretic damping of vertical link beam placed above chevron bracing is exclusively utilized to dissipate the energy of moderate earthquakes through web plastic shear distortion while the rest of the structural elements are in elastic range. Under strong earthquakes, plastic deformation of VLB will be halted via restraining it by Stopper Device (SD) and further imposed displacement subsequently causes yielding of the knee elements located at the bottom of chevron bracing to significantly increase the energy dissipation capacity level. In this paper first by studying the knee yielding mode, a suitable shape and angle for diagonal-knee bracing is proposed. Then finite elements models are developed. Monotonic and cyclic analyses have been conducted to compare dissipation capacities on three individual models of passive systems (CK-VLB, knee braced system and SPS system) by General-purpose finite element program ABAQUS in which a bilinear kinematic hardening model is incorporated to trace the material nonlinearity. Also quasi-static cyclic loading based on the guidelines presented in ATC-24 has been imposed to different models of CK-VLB with changing of vertical link beam section in order to find prime effectiveness on structural frames. Results show that CK-VLB system exhibits stable behavior and is capable of dissipating a significant amount of energy in two separate levels of lateral forces due to different probable earthquakes.

• Journal of Korean Society of Steel Construction
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• v.9 no.4 s.33
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• pp.557-578
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• 1997

The objective of the study in this paper was to develop a beam-column element to model members with purely flexural yielding, as well as members with yielding under combined flexure and axial force during severe earthquake ground motins. The developed element can be considered as an one-component series hinge type model. It has the capability to model plastic axial deformation and changes in axial stiffness, and employs hardening rules to handle monotonic, cyclic or arbitrary loading. In general, when compared to experimental results and fiber model predictions, the element showed significantly better performance than the bilinear hinger model and could properly model the beam-column behavior of bare steel members in moment resisting frames. The developed element can more accurately predict local deformation demands and overall responses of structural systems under earthquake loadings than the bilinear hinge element.

• Journal of Korean Public Health Nursing
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• v.19 no.2
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• pp.249-260
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• 2005

Purpose: The purpose of this study is to analyze the realities related with the in-home falls of the elderly and also the factors that affect on the fails. Method: The data collection was carried out from January 10 to 13, 2005. The subjects of this study were 201 in-home elderly people over age 60 who resided at G city of Jeollabuk-do. Result: The following are the results from the analysis of collected data with using the SPSS program. 1. The number of people who experienced fall injuries was 51.7% within three years. Most cases of falls occurred in winter (52.4%), on roads (52.9%), wearing sports shoes (56.7%), when walking (56.7%), loosing their balance (54.8%), and slipping (54.8%). 2. The factors yielding the difference between the groups of elderly with the experience of fail injury and the group of elderly with no experience of falls showed a statistical significance for gender (p=.000), last academic career (p=.049), and number of people in the family (p=.041). 3. Among the factors related with health, the factors yielding the difference between the group of elderly with the experience of falls and the group of elderly with no experience of fails showed statistical significance for drinking (p=.015), dizziness (p=.000) and level of drug intakes (p=.015). 4. The elderly with the experience of fall injury as compared with the group of aged people with no experience of falls showed a higher degree of depression (p=.009). 5. From the result of logistic regression analysis to explore the factors affecting the experience of fall injury, it was found that there was a significant result for gender (p=.002) and depression (p=.018). Women as compared with men and the elderly with depression showed a higher rate of danger in falls. Conclusion: Based on the above results, it is expected that fall prevention programs are needed with regard to the general characteristics and health related characteristics, that is, the individual danger factors should be focused on such depression and gender as being the most important variables affecting the experience of falls.

• Advances in concrete construction
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• v.8 no.3
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• pp.173-185
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• 2019

This article presents a comparative study of the effect of steel layouts on the seismic behavior of transition steel-concrete composite connections, both experimental and analytical investigations of concrete filled steel tube-reinforced concrete (CFST-RC) and steel reinforecd concrete-reinforced concrete (SRC-RC) structures were conducted. The steel-concrete composite connections were subjected to combined constant axial load and lateral cyclic displacements. Tests were carried out on four full-scale connections extracted from a real project engineering with different levels of axial force. The effect of steel layouts on the mechanical behavior of the transition connections was evaluated by failure modes, hysteretic behavior, backbone curves, displacement ductility, energy dissipation capacity and stiffness degradation. Test results showed that different steel layouts led to significantly different failure modes. For CFST-RC transition specimens, the circular cracks of the concrete at the RC column base was followed by steel yielding at the bottom of the CFST column. While uncoordinated deformation could be observed between SRC and RC columns in SRC-RC transition specimens, the crushing and peeling damage of unconfined concrete at the SRC column base was more serious. The existences of I-shape steel and steel tube avoided the pinching phenomenon on the hysteresis curve, which was different from the hysteresis curve of the general reinforced concrete column. The hysteresis loops were spindle-shaped, indicating excellent seismic performance for these transition composite connections. The average values of equivalent viscous damping coefficients of the four specimens are 0.123, 0.186 and 0.304 corresponding to the yielding point, peak point and ultimate point, respectively. Those values demonstrate that the transition steel-concrete composite connections have great energy dissipating capacity. Based on the experimental research, a high-fidelity ABAQUS model was established to further study the influence of concrete strength, steel grade and longitudinal reinforcement ratio on the mechanical behavior of transition composite connections.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2008.10a
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• pp.304-307
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• 2008

In order to evaluate the effect of permanent softening behavior on springback prediction, 2D-draw bending simulations were compared with experiments for friction stir welded DP590 steel sheets. To account fur the nonlinear hardening behavior, the combined isotropic-kinematic hardening law was utilized with and without considering the permanent softening behavior during reverse loading. Also, the non-quadratic orthotropic yield function, Yld2000-2d, was used to describe the anisotropic initial-yielding behavior of the base sheet while anisotropic properties of the weld zone were ignored for simplicity.