• 제목/요약/키워드: general helix

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The Emotional Dimensions of North Korean Politics through the Lens of Historical Institutionalism

  • Kim, Hwajung
    • Journal of Contemporary Eastern Asia
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    • 제21권2호
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    • pp.13-26
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    • 2022
  • This study explores the following research question to address issues linked to emotions, identity, and institutions: how has the cult (institution) of the three Kims affected North Koreans' strong sense of nationalism (emotion), which is based on their Juche ideology (identity)? This paper investigates four fundamental elements of historical institutionalism: time boundedness, path dependency, institutional changes, and the shadow of the past. First, time boundedness illustrates how culture and education have been used to build trust and loyalty in the general public to construct individual and family cults. Second, path dependence reveals how the Songbun system has resulted in strong nationalism throughout Rodongdang's institutionalization. Third, institutional changes highlight the significance of age divides, as different age groups do not always support the three Kims' cult. Finally, the shadow of the past helps us understand the primary processes for generating mass ardent nationalism in the form of powerful impulses for self-sacrifice.

GOVERNMENT-CIVIC GROUP CONFLICTS AND COMMUNICATION STRATEGY: A TEXT ANALYSIS OF TV DEBATES ON KOREA'S IMPORT OF U.S. BEEF

  • Cho, Seong Eun;Choi, Myunggoon;Park, Han Woo
    • Journal of Contemporary Eastern Asia
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    • 제11권1호
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    • pp.1-20
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    • 2012
  • This study analyzes messages from Korean TV debates on the conflict over U.S. beef imports and the process of negotiations over the imports in 2008. The authors have conducted a content analysis and a semantic network analysis by using KrKwic and CONCOR. The data was drawn from nine TV debates aired by three major TV networks in Korea (MBC, KBS, and SBS) from 27 April 27 2008 to 6 July 2008. The results indicate substantial differences in the semantic structure between arguments by the government and those by civic groups. We also investigated the relationship between the terms frequently used by both sides (i.e., the government and civic groups), and the terms used exclusively by one side. There was a gradual increase in the number of terms frequently used by both sides over time, from the formation of the conflict to its escalation to its resolution. The results indicate the possibility of general agreement in conflict situations.

5축 가공용 Post-Processor 개발에 관한 연구 (Study on the Development of Post-Processor for 5-Axis NC Machining)

  • 조은정;황종대;정윤교
    • 한국공작기계학회논문집
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    • 제15권3호
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    • pp.53-58
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    • 2006
  • This study deals with the method of post-processing in the automatic tool path generation for 5-axis NC machining. The 5-axis NC machining cannot only cope with the manufacturing of complicated shapes, but also offers numerous advantages such as reasonable tool employment, great reduction of set-up process and so on. Thus 5-axis NC machining has been used for aircraft parts, mold and die as well as for complicated shapes such as impeller, propeller and rotor. However, most of the present CAM systems for 5-axis NC machining have limited functions in terms of tool collision, machine limits and post-processing. Especially 5-axis machine configurations are various according to the method which the rotational axes are adapted with the table and spindle. For that reason, In many cases the optimal numerical control (NC) data cannot be obtained or considerable time is consumed. To solve this problem, we applied a general post-processor for 5-axis NC machining. The validity of this post-processor should be experimentally confirmed by successfully milling to a helix shaped workpiece.

5축가공용 Post-Processor 개발에 관한 연구 (Study on the Development of Post-Processor for 5-Axis NC machining)

  • 황종대;정윤교;정종윤
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2005년도 추계학술대회 논문집
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    • pp.370-374
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    • 2005
  • This study deals with the method of post-processing in the automatic tool path generation for 5-axis NC machining. The 5-axis NC machining cannot only cope with the manufacturing of complicated shapes, but also offers numerous advantages such as reasonable tool employment, great reduction of set-up process and so on. Thus 5-axis NC machining has been used fur aircraft parts, mold and die as well as for complicated shapes such as impeller, propeller and rotor. However, most of the present CAM systems for 5-axis NC machining have limited functions in terms of tool collision, machine limits and post-processing. Especially 5-axis machine configurations are various according to the method which the rotational axes are adapted with the table and spindle. For that reason, in many cases the optimal numerical control (NC) data cannot be obtained or considerable time is consumed. To solve this problem, we applied a general post-processor fur 5-axis NC machining. The validity of this post-processor should be experimentally confirmed by successfully milling to a helix shaped workpiece.

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The Merits of Social Credit Rating in China? An Exercise in Interpretive Pros Hen Ethical Pluralism

  • Clancy, Rockwell F.
    • Journal of Contemporary Eastern Asia
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    • 제20권1호
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    • pp.102-119
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    • 2021
  • Social credit rating in China (SCRC) has been criticized as "dystopian" and "Orwellian," an attempt by the Communist Party to hold onto power by exerting ever greater control over its citizens. To explain such measures, value differences are often invoked, that Chinese value stability and cooperation over privacy and freedom. However, these explanations are oversimplifications that result in ethical impasses. This article argues social credit rating should be understood in terms of the commonly human problem of large-scale cooperation. To do so, this paper relies on a cultural evolutionary framework and is an exercise in interpretive pros hen ethical pluralism, attempting to understand how apparently irresolvable cultural differences stem from common human concerns. Wholesale condemnation of SCRC fails to acknowledge the serious, intractable nature of problems resulting from a lack of trust in China. They take for granted the existence of institutions ensuring largescale, anonymous cooperation characteristic of - but somewhat unique to - Western Educated Industrialized Rich and Democratic (WEIRD) cultures. Because of its history and rapid development, China lacks the institutions necessary to ensure such cooperation, and because of anti-social punishment, social credit rating might be one of the few ways to ensure cooperation at this scale. The point is not to defend social credit rating in general, but to raise the possibility of its defense in China and show one way this would be done.

Big Data and Knowledge Generation in Tertiary Education in the Philippines

  • Fadul, Jose A.
    • Journal of Contemporary Eastern Asia
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    • 제13권1호
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    • pp.5-18
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    • 2014
  • This exploratory study investigates the use of a computational knowledge engine (WolframAlpha) and social networking sites (Gmail, Yahoo and Facebook) by 200 students at De La Salle-College of Saint Benilde, their "friends" and their "friends of friends" during the 2009 through 2013 school years, and how this appears to have added value in knowledge generation. The primary aim is to identify what enhances productiveness in knowledge generation in Philippine Tertiary Education. The phenomenological approach is used, therefore there are no specific research questions or hypotheses proposed in this paper. Considering that knowledge generation is a complex phenomenon, a stochastic modelling approach is also used for the investigation that was developed specifically to study un-deterministic complex systems. A list of salient features for knowledge generation is presented as a result. In addition to these features, various problem types are identified from literature. These are then integrated to provide a proposed framework of inclusive (friendly) and innovative social networks, for knowledge generation in Philippine tertiary education. Such a framework is necessarily multidisciplinary and useful for problem-solving in a globalized and pluralist reality. The implementation of this framework is illustrated in the three parts of the study: Part 1: Online lessons, discussions, and examinations in General Psychology, Introduction to Sociology, and Life and Works of Jose Rizal, for the author's students in De La Salle-College of Saint Benilde; Part 2: Facebook Report analytics of students and teachers, their friends and their friends of friends via WolframAlpha; and Part 3: Social Network Analysis of the people and groups influencing the courses' scope-and-sequence in the new General Education Curriculum for Tertiary Schools and Institutions in the Philippines.

Structural Origin for the Transcriptional Activity of Human p53

  • Lee, Si-Hyung;Park, Kyu-Hwan;Kim, Do-Hyung;Choung, Dong-Ho;Suk, Jae-Eun;Kim, Do-Hyung;Chang, Jun;Sung, Young-Chul;Choi, Kwan-Yong;Han, Kyou-Hoon
    • BMB Reports
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    • 제34권1호
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    • pp.73-79
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    • 2001
  • Transcriptional activation domains are known to be inherently "unstructured" with no tertiary structure. A recent NMR study, however, has shown that the transactivation domain in human p53 is populated with an amphipathic helix and two nascent turns. This suggests that the presence of such local secondary structures within the overall "unstructured" structural framework is a general feature of acidic transactivation domains. These pre-existing local structures in p53, formed selectively by positional conserved hydrophobic residues that are known to be critical for transcriptional activity, thus appear to constitute the specific structural motifs that regulate recognition of the p53 transactivation domain by target proteins. Here, we report the results of a NMR structural comparison between the native human p53 transactivation domain and an inactive mutant (22L,23W$\rightarrow$22R,23S). Results show that the mutant has an identical overall structural topology as the native protein, to the extent that the amphipathic helix formed by the residues 18T 26L within the native p53 transactivating domain is preserved in the double mutant. Therefore, the lack of transcriptional activity in the double mutant should be ascribed to the disruption of the essential hydrophobic contacts between the p53 transactivation domain and target proteins due to the (22L,23W$\rightarrow$22R,23S) mutation.

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Structural basis of novel TRP14, thioredoxin-related protein that regulates TNE-$\alpha$ signaling pathways

  • Woo, Joo-Rang;Jeong, Woo-Jin;Rhee, Sue-Goo;Ryu, Seong-Eon
    • 한국결정학회:학술대회논문집
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    • 한국결정학회 2003년도 춘계학술연구발표회
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    • pp.18-18
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    • 2003
  • Thioredoxin (Trx) is a small redox protein that is ubiquitously distributed from achaes to human. In diverse organisms, the protein is involved in various physiological roles by acting as electron donor and regulators of transcription and apoptosis as well as antioxidants. Sequences of Trx within various species are 27~69% identical to that of E. coli and all Trx proteins have the same overall fold, which consists of central five β strands surrounded by four α helices. The N-terminal cysteine in WCGPC motif of Trx is redox sensitive and the motif is highly conserved. Compared with general cysteine, the N-terminal cysteine has low pKa value. The result leads to increased reduction activity of protein. Recently, novel thio.edoxin-related protein (TRP14) was found from rat brain. TRP14 acts as disulfide reductase like Trx1, and its redox potential and pKa are similar to those of Trx1. However, TRP14 takes up electrons from cytosolic thioredoxin reductase (TrxR1), not from the mitochondrial thioredoxin reductase (TrxR2). Biological roles of TES14 were reported to be involved in regulating TNF-α induced signaling pathways in different manner with Trx1. In depletion experiments, depletion of TRP14 increased TNF-α induced phosphorylation and degradation of IκBα more than the depletion Trx1 did. It also facilitated activation of JNK and p38 MAP kinase induced by TNF-α. Unlike Trx1, TRP14 shows neither interaction nor interference with ASK1. Here, we determined three-dimensional crystal structure of TRP14 by MAD method at 1.8Å. The structure reveals that the conserved cis-Pro (Pro90) and active site-W-C-X-X-C motif, which may be involved in substrate recognition similar to Trx1 , are located at the beginning position of strand β4 and helix α2, respectively. The TRP14 structure also shows that surface of TRP14 in the vicinity of the active site, which is surrounded by an extended flexible loop and an additional short a helix, is different from that of Trx1. In addition, the structure exhibits that TRP14 interact with a distinct target proteins compared with Trx1 and the binding may depend mainly on hydrophobic and charge interactions. Consequently, the structure supports biological data that the TRP14 is involved in regulating TNF-α induced signaling pathways in different manner with Trx1.

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토양굴취력이 향상된 스크류형 경량 식혈기 개발(I) - 설계 및 제작 - (Development of Screw-Type Handy Earth Auger for an Improved Digging Efficiency(I) - Design and Manufacture -)

  • 김진현;이재현;김기동;고치웅;김동근
    • 농업생명과학연구
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    • 제50권3호
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    • pp.31-41
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    • 2016
  • 본 연구는 산림조성사업에 있어서 가장 큰 비중을 차지하는 인건비와 생산비용을 절감시키고 경사가 험준한 우리나라 산림지형에서 유용하게 이용 가능한 경량 식혈기를 개발하고자 수행하였다. 제작된 1차 시제품은 토양을 굴취하는 스크류(screw) 부분과 동력원인 배터리로 구성되고, 제원은 스크류의 길이 170mm, 상단폭 60mm, 하단폭 47mm, 나선각(Helix angle)은 23°, 그리고 Tip은 송곳형태로 길이 50mm로 설계·제작하였고 무게를 줄이기 위해 1줄 스크류를 채택하였다. 또한, 동력원으로는 회전용 DC Motor(WD-6G2425, WONILL, Korea)로 최대 Torque는 30㎏f-cm, 회전속도는 20~30rpm으로 설정하였다. 감속비는 30:1의 K6G30C 감속기에 무부하 상태로 사용한 결과 48시간 작동하였다. 그리고 배터리는 경량식재기의 개발을 목표로 하기 때문에 무게를 고려하여 리듐배터리를 사용하였으며, 포트묘의 길이가 15cm 내외인 점을 고려하면 스크류의 회전력이 최대 100kgf-cm정도로 설계하였다. 1차 시제품의 성능을 평가하기 위해 조사지에서 굴취시 스크류에 소요되는 회전력을 측정한 결과, 회전력이 가장 큰 곳은 A area(단단한 초지), 그 다음은 F area(경사가 40°인 산지), E area(경사가 30°인 산지)의 순서로 나타났다. 토양의 굴취 회전력은 일반적으로 깊이가 깊어질수록 높아지는 경향을 보이고 있으며, 대체적으로 토양의 깊이 10cm 부근에서 높은 경향을 보였다.

개선된 드릴 디자인을 적용한 간소화된 드릴링 과정에 관한 연구 (A study on simplified procedure of enhanced designed implant drill)

  • 윤지훈;전계록;윤미정;허중보;정창모
    • 대한치과의사협회지
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    • 제53권5호
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    • pp.368-376
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    • 2015
  • Purpose : The objective of this research was to develop a more simplified drilling procedure with an enhanced implant drill. Materials and Methods : The drill enhanced design factors enabled implantation of Dia. 5.0mm fixture with only 2 times drilling which is more simplified drilling procedure. The enhanced drill was designed with 2 flutes, 2-phase or 3-phase formed drill tip and 25 degrees of helix angle. The proposed drilling procedure (2 times) was compared with a general drilling process (4 times) in terms of temperature changes, cutting time and ISQ value. Results : The simplified drilling procedure indicated less heat than a conventional drilling procedure (p<0.05). The enhanced drill showed significantly shorter drilling time than a conventional drill (p<0.05). On the other hand, higher insertion torque and ISQ value were observed on the the suggested drilling procedure than the conventional drilling procedure (p<0.05). Conclusion : A simplified drilling procedure with the newly designed drill could provide higher effectiveness and safety of dental implant operations under properly controlled external conditions, such as irrigation and RPM of drilling.