• 한국사회복지학
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• 제56권3호
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• pp.89-112
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• 2004

정신장애인의 임파워먼트를 위해서는 개인 내적인 변화와 더불어 사회적 인식의 변화가 필요하다. 자원봉사활동은 바로 자기실현과 자존감 증대와 같은 내적 변화와 더불어 정상화 및 가치 있는 사회적 역할 강화를 통해 참여자에 대한 사회적 인식 변화를 가져올 수 있는 기제로 알려져 있다. 이에 본 연구에서는 정신장애인이 자원봉사 서비스의 제공자로서 지역사회에 참여하는 프로그램을 구조화하고, 이의 실천을 통해 임파워먼트 효과성을 살펴보고자 하였다. 이를 위하여 본 연구에서는 첫째, 정신장애인 뿐 아니라 봉사활동의 장인 지역사회의 봉사 준비과정을 체계화하고, 둘째, 정신장애인들과 봉사활동을 함께 하는 일반인 협력자를 활용하는 것을 특징으로 하는 정신장애인 자원봉사프로그램을 개발하였다. 그리고 이 자원봉사 프로그램에는 시설거주 정신장애인 13명과 이들의 협력자인 사회복지전공 대학생 10명이 참석하였다. 프로그램 시행 결과 자원봉사활동에 참여한 실험집단의 정신장애인은 통제집단에 비해 자아이미지 측면에서 임파워먼트의 효과가 있었던 것으로 나타났으며, 일반시민으로서 프로그램에 같이 참여한 협력자들은 사전에 비해 사후에 정신장애인에 대한 태도 즉, 권위주의, 자비심, 사회생활제한, 그리고 지역정신보건 측면에서 모두 긍정적인 변화가 있었던 것으로 입증되었다. 이러한 결과는 그동안 봉사 대상자로 머물러온 정신장애인도 자신의 능력을 활용하여 봉사 제공자가 될 수 있다는 것을 보여주는 것일 뿐 아니라, 이러한 활동을 통해 자기 자신에 대한 인식과 일반인의 태도에도 긍정적 변화를 가져올 수 있음을 나타내는 것이다. 본 연구를 통해 제시된 정신장애인 자원봉사 프로그램이 실천현장의 상황에 맞게 활용되어 정신장애인의 임파워먼트와 지역사회 통합에 기여할 수 있기를 기대해 본다.

• 한국사회복지학
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• 제59권1호
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• pp.117-143
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• 2007

본 연구의 목적은 활동보조서비스의 성과 및 그 영향요인을 파악하여 한국적 적용가능성에 대한 토대를 마련하고자 하는 것이다. 이 연구를 위해 전국 10개 장애인자립생활센터로부터 활동보조서비스를 이용하고 있는 중증장애인 201명에게 우편조사를 실시하였다. 연구결과는, 활동보조서비스를 이용함으로써 첫째, 장애인들의 주관적 건강상태가 향상되었고, 둘째, 심리적 자기의존도가 증가하고, 서비스 만족도가 높게 나타났으며, 셋째, 지역사회참여 및 취업이 증가하고, 취업/고용유지에 대한 자신감이 향상된 것을 보여 주었다. 또한 활동보조서비스 성과에 영향을 미치는 요인을 살펴보면, 심리적 자기의존의 경우 월평균 가구소득이 높고 1회 평균이용시간이 길수록 타인이 아닌 자기 자신에게 심리적으로 의존하는 정도가 높아지는 것으로 나타났다. 지역사회참여의 경우, 연령이 낮고 월평균 가구소득이 낮을수록, 그리고 서비스 이용기간이 길수록 지역사회에 참여하는 정도가 높아지는 것으로 나타났다. 고용의 경우, 장애지속기간이 길고 서비스 이용기간이 길수록 취업이 늘어나는 것으로 나타났다. 마지막으로 취업/고용유지에 대한 자신감의 경우, 월평균 가구소득이 높고, 장애등급이 낮을수록 취업/고용유지에 대한 자신감이 높아지는 것으로 나타났다. 이러한 연구결과는 현재 우리나라에서 시범사업으로 진행하고 있는 활동보조서비스를 국가적으로 제도화할 수 필요성이 있음을 보여 주고 있다.

• Tuberculosis and Respiratory Diseases
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• 제38권2호
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• pp.143-154
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• 1991

Pneumconiosis is a sort of pulmonary fibrosis consequent to the inhalation of the respirable dusts. Thus, the pathogenesis of silicosis have concentrated largely on the early response of alveolar macrophage and the later fibroblastic stimulation. But the role of the other cells and continuing cell injury in the pathogenesis has not been fully studied. And the chemical factors such as prostaglandin, fibroblast stimulating factor and inhibiting factor and chemotaxin are also participated in the mechanism of pulmonary fibrosis in silicosis. In order to clarify the role of alveolar cells and prostaglandin, we investigated the changes of the cellularities in bronchoalveolar lavage fluid and tissue pathology in the experimental silicosis with the time sequence. The experimental animals were divided into 3 groups; control group received only intratracheal injection of 0.5 ml saline, silica group received the intratracheal instillation of 40 mg silica with the same amount saline, and aspirin group received 450 mg/kg of aspirin after silica instillation. The results were as follows: 1) The total cells of bronchoalveolar lavage fluid in the silica group markedly increased in comparison with the control group, but there was no significant difference between the silica and aspirin groups. 2) The percentages of alveolar macrophages to the total number of cells in the silica group tended to be lower than those in the control group and also lower than those in the aspirin group at the 1st week after silica instillation. 3) The percentages of neutrophils to the total number of cells in the silica group were significantly higher than those in the control group during the entire period and also higher than those in the aspirin group at the 3rd day after silica instillation. 4) In the silica group, the percentages of lymphocytes to the total number of cells were increased 143 progressively with the time course and those were significantly higher than those in the control group from the 3rd week after silica administration. There were marked differences of lymphocyte percentages between the silica and aspirin groups at the 1st week after silica instillation. 5) The inflammatory change was observed in the rat lung at the 1st day after silica instillation. Also the silicotic nodule appeared in the silica group at the 1st week but we could not find out that nodule in the aspirin group at that time. The fibrotic changes in the rat lung tended to be increased progressively with the time course, therefore, the diffuse fibrotic pattern appeared in the whole field at the 20th week after silica instillation. 6) By the electron microscopy, there were gradual increases of phagosomes and vacuoles in the alveolar macrophage in the silica group as compared with the control group. These results suggest that the neutrophils and the lymphocytes have also participated in the pulmonary fibrosis even though the alveolar macrophage has a major role, and prostaglandin mediate the inflammation and pulmanary fibrosis in the experimental silicosis.

• Journal of Ginseng Research
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• 제41권3호
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• pp.247-256
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• 2017

Background: KG-135, a standardized formulation enriched with Rk1, Rg3, and Rg5 ginsenosides, has been shown to inhibit various types of cancer cells; however, the underlying mechanisms are not fully understood. In this study, we explored its effects in A549 human lung cancer cells to investigate the induction of Forkhead Class box O3a (FOXO3a) and autophagy. Methods: Cell viability was determined by sulforhodamine B staining. Apoptosis and cell cycle distribution were analyzed using flow cytometry. The changes of protein levels were determined using Western blot analysis. Autophagy induction was monitored by the formation of acidic vesicular organelles stained with acridine orange. Results: KG-135 effectively arrested the cells in G1 phase with limited apoptosis. Accordingly, a decrease of cyclin-dependent kinase-4, cyclin-dependent kinase-6, cyclin D1, and phospho-retinoblastoma protein, and an increase of p27 and p18 proteins were observed. Intriguingly, KG-135 increased the tumor suppressor FOXO3a and induced the accumulation of autophagy hallmark LC3-II and acidic vesicular organelles without an increase of the upstream marker Beclin-1. Unconventionally, the autophagy adaptor protein p62 (sequestosome 1) was increased rather than decreased. Blockade of autophagy by hydroxychloroquine dramatically potentiated KG-135-induced FOXO3a and its downstream (FasL) ligand accompanied by the cleavage of caspase-8. Meanwhile, the decrease of Bcl-2 and survivin, as well as the cleavage of caspase-9, were also drastically enhanced, resulting in massive apoptosis. Conclusion: Besides arresting the cells in G1 phase, KG-135 increased FOXO3a and induced an unconventional autophagy in A549 cells. Both the KG-135-activated extrinsic FOXO3a/FasL/caspase-8 and intrinsic caspase-9 apoptotic pathways were potentiated by blockade of autophagy. Combination of KG-135 and autophagy inhibitor may be a novel strategy as an integrative treatment for cancers.

• 한국컴퓨터정보학회논문지
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• 제21권6호
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• pp.9-19
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• 2016

In finance literature, stock liquidity showing how stocks can be cashed out in the market has received rich attentions from both academicians and practitioners. The reasons are plenty. First, it is known that stock liquidity affects significantly asset pricing. Second, macroeconomic announcements influence liquidity in the stock market. Therefore, stock liquidity itself affects investors' decision and managers' decision as well. Though there exist a great deal of literature about stock liquidity in finance literature, it is quite clear that there are no studies attempting to investigate the stock liquidity issue as one of decision making problems. In finance literature, most of stock liquidity studies had dealt with limited views such as how much it influences stock price, which variables are associated with describing the stock liquidity significantly, etc. However, this paper posits that stock liquidity issue may become a serious decision-making problem, and then be handled by using data mining techniques to estimate its future extent with statistical validity. In this sense, we collected financial data set from a number of manufacturing companies listed in KRX (Korea Exchange) during the period of 2010 to 2013. The reason why we selected dataset from 2010 was to avoid the after-shocks of financial crisis that occurred in 2008. We used Fn-GuidPro system to gather total 5,700 financial data set. Stock liquidity measure was computed by the procedures proposed by Amihud (2002) which is known to show best metrics for showing relationship with daily return. We applied five data mining techniques (or classifiers) such as Bayesian network, support vector machine (SVM), decision tree, neural network, and ensemble method. Bayesian networks include GBN (General Bayesian Network), NBN (Naive BN), TAN (Tree Augmented NBN). Decision tree uses CART and C4.5. Regression result was used as a benchmarking performance. Ensemble method uses two types-integration of two classifiers, and three classifiers. Ensemble method is based on voting for the sake of integrating classifiers. Among the single classifiers, CART showed best performance with 48.2%, compared with 37.18% by regression. Among the ensemble methods, the result from integrating TAN, CART, and SVM was best with 49.25%. Through the additional analysis in individual industries, those relatively stabilized industries like electronic appliances, wholesale & retailing, woods, leather-bags-shoes showed better performance over 50%.

• 한국식품과학회지
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• 제20권2호
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• pp.188-193
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• 1988

유채박의 활용성을 높이기 위하여 발아에 따른 일반성분, 지방산, 무기물의 함량변화를 측정한 결과는 다음과 같다. 유채의 백립중은 발아 72시간후에 최초 무게의 두배가 되었으며 이때 자엽이 출현하였다. 발아에 따라 수분과 조회분은 큰 변화가 없었으나 조단백질과 가용성무질소물의 함량은 감소하는 경향을 나타내었다. 발아전 시료의 지방산 조성은 oleic, erucic, linoleic, linolenic acid가 각각 24.6, 15.5, 10.6, 9.5%이었으며 stearic, palmitic, arachidic acid가 각각 1.0, 2.4, 5.3%이었다. 발아후 96시간까지는 각 지방산 함량이 모두 조금씩 감소하다가 120시간에는 증가하는 경향을 나타내었으며 지방산간의 차이는 별로 없었다. 발아전 시료의 무기물 함량은 인, 칼슘, 마그네슘, 아연, 망간, 구리, 철이 각각 6367, 3068, 2667, 80.3, 26.5, 15.9, 94.4ppm이었고 나트륨은 극히 미량이 검출되었다. 발아에 따른 무기물 함량은 초기에 서서히 감소하다가 120시간에 약간 증가하는 경향을 나타내었으며, 철의 경우 48시간에 급격히 증가하다가 감소하는 경향을 나타내었다.

• 한국병원경영학회지
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• 제8권2호
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• pp.24-48
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• 2003

It is important how the leader leads the organizational members with leadership appropriate to environment changes as the leader has great influence on the management of hospital organization. These data were collected from the questionnaire surveyed, from February 14 through February 28, 2003, to 218 people among those in the field of doctorship, management administration, nursing, technology, medical engineering, management engineering, and general affairs, working for three hospitals under S medical foundation in Pusan. The principal findings of this research are as below : 1. Type of leadership and job satisfaction had positive correlation in terms of both transformational and transactional leadership, with former having more relation than the latter. 2. Type of leadership and organizational commitment had positive correlation in terms of intellectual stimulus and situational rewards, having little relation statistically. 3. Type of leadership and turnover intentions had negative correlation only in individual consideration, situational rewards, and exceptional management, showing that transactional leadership had more relation than transformational leadership. 4. In terms of leadership and its effect on the organizational performance and turnover intentions, transformational leadership had more correlation than transactional leadership. But transactional leadership also turned out to have effect on organizational performance. When transformational leadership used, turnover intentions were lower than when transactional leadership used. However, both transformational and transactional leadership had negative correlation to turnover intentions. 5. Effect that type of leadership according to job classification, status, age, and academic career has on organizational performance and turnover intentions was differed by those factors; especially, in the occupation of doctor, both transformational and transactional leadership had positive correlation to turnover intentions. 6. Regression analysis on the factors of organizational performance and turnover intentions showed that higher age had positive correlation to the organizational performance in terms of socio-demographical features and that the more leadership was used for charismatic and situational rewards and the less leadership was used for intellectual stimuli, the higher organizational performance was likely. In short, hospital operators and managers should examine each manager's qualification, type, and style of leadership in the hospital organization, and they must develop lasting programs for effective education and training for developing characteristics of leadership are in needed to have managers with appropriate managerial mind to respective post and status. It should be kept in mind that manager's leadership especially has great effect on members' goal-setting, goal-achievement, organizational performance, and turnover intentions as it is a decisive factor of organizational members' attitude and motivation.

• 대한치과기공학회지
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• 제11권1호
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• pp.35-45
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• 1989

This study was carried out from June, 20, to October 22, 1988, for the purpose of researching on the complaint ratio of Respiratory symptoms of the dental laboratory technicians in Seoul. In this study, aiming to find out complaint ratio of respiratory symptoms of the dental laboratory, SNU-81-AL were applied, at random, to 193 dental laboratory technicians at 39 dental laboratories, as the research group, and to 178 clinical laboratory technicians at 10 general hospitals, as the control group, and above two groups were compared with each other. The following results were obtained from this research. 1. The quantity of respirable dust under 5$\mu$m measured at the dental laborartories was, on an average as well, 5$mg/m^3$-minimum 1.56$mg/m^3$), and the density of CO was, on an average as well, 5.0ppm(Mx 7.0-Mn 3.0). 2. The complaint ratio of five main respiratory symptoms(cough, phlegm, wheezing, nasal catarrh & cold, breathlessness) was, on an average, 44.3% at the dental laboratory technicians, phlegm was the major symptom complained by the greatest number of the technicians. 22.4% of the clinical laboratory technicians complained above 5 main respiratory symptoms, nassal catarrh & cold was the mostly complained symptoms among them. There showed a consideraly significant difference at the complaint ratio between the above 2 occupations(P<0.005). 3. There showed no paticular significant difference between male and female, at the complaint ratio of the dental laboratory technicians. However, there showed a considerable significant difference according to their sexuality, in case of the clinical laboratory technicians. 4. Considered from th view point of age, the highest age group was 20-29 with its average 48.5%, in case of dental laboratory technicians. The highest age group among the clinical laboratory technicians was over 40 age with its 28.7%. There showed no particular significant differences between to tow occupations. 5. Considered from the view point of work period, the highest work period group was 0-3 years with average 47.8%, in case of dental laboratory The highest work period group among the clinical laboratory technicians was 16 years with its 25.2%. There showed no particuar significant differences between the two occupations. 6. Considered from the view point of smoking, phlegm was complained by much more smokers than non-smokers, in both occupations. In case of non-smokers, many complained about nassal catarrh & cold. There showed no particular significant differences between the smokers and the non-smokers.

• 대한치과기공학회지
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• 제34권3호
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• pp.263-271
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• 2012

Purpose: The purpose of this research was to examine department satisfaction for improving the competitiveness of department of dental technology and providing basic data for students successful guidance. Methods: The study subject were 560 students from 4 colleges, and they were selected by the convenient sampling method. Data for this survey was obtain by self-administration method. This questionnaire consist of general characteristics, the awareness of before entering department of dental technology, the satisfaction of department of dental technology, an opinion about change of one's course and temporary absence. Results: About the time of selecting their major, 70.1% of students answered the most before highschool. Department of dental technology and the most common source of information in selecting a majors is the person oneself(52.6%). The person who answers because of knowing a little bit for the question asking the priori knowledge of department of dental technology showed up as 66.3%. About the motivation for selection their major, 37.4% of students answered the most it seemed to be a future prospect. As to the extend of department satisfaction, the satisfaction showed up as 63.3%, but the extend of satisfaction was exposed to reduce as the grade increased. The dissatisfaction factor is the difficulty of the theory(29.8%). Many students do not want to change their majors even if they are provided with the chance to do so(68.7%). From the survey related to the experience of thinking over temporary absence and drop out, 56.8% of students responded they had experienced thinking about that. Current feelings after department selection was found to be the most significant factor that affects satisfaction of department of dental technology(Adjusted $R^2$=48.3%). Conclusion: The extend of satisfaction of the women is low. The extend of satisfaction reduces as the grade increases. The school subject extend of satisfaction can know that ratio about of considering the leave of absence and voluntary withdrawal increases. Therefore, the plan of education that women can adapt the women o the school subject well and that it can be satisfied is sought for. It is considered that effort promoting the extend of satisfaction is needed as the grade increases.

• 한국전자통신학회논문지
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• 제8권11호
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• pp.1785-1792
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• 2013

척수손상환자들에게 호흡기계 합병증의 발생률과 이로 인한 사망률은 여전히 높은 비율을 차지하고 있으며, 이 중 폐렴이 가장 주요한 사망의 원인이 되고 있다. 본 연구는 남자 경수손상환자들에게 들숨근 강화를 목적으로 한 호흡운동이 호흡기능 및 삶의 질 향상에 어떤 영향을 미치는지 알아보기 위해 실시되었다. 연구대상은 마비수준 C4-C6의 아급성, 만성 경수손상 환자 중 현재 흡연을 하지 않는 남자 환자 17명이었으며, 주 3회, 총 6주간 들숨근 강화훈련을 실시하였다. 훈련 전후에 호흡곤란척도와 삶의 질을 자가측정 하였다. 연구 결과 호흡기능변화는 만성군에서만 유의한 감소(p<0.01)가 있었다. 삶의 질 변화에서는 아급성군은 VT(활력)에만 유의한 향상(p<0.05)이 있었고, 만성군은 GH(전반적인 건강상태), BP(통증), VT(활력)에서 유의한 향상(p<0.05, p<0.01)이 있었다. 본 연구에서는 들숨근 강화훈련이 호흡곤란을 경감시키고 삶의 질을 향상시켰다.