• 한국의학물리학회지:의학물리
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• 제29권1호
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• pp.23-28
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• 2018

The purpose of this study is to build a database of patient information for efficient radiotherapy management. Microsoft Office Access was used to build the database owing to its convenience and compatibility. The most important aspect when building the patient database is to make the input and management of patient information efficient at every step of radiotherapy process. The information input starts from the patient's first visit to the radiation therapy department and ends upon completion of the radiotherapy. The forms for each step of radiotherapy process include the patient information form, the radiotherapy schedule form, the radiotherapy information form, the simulation order form, and the patient history form. Every form is centrically connected to the radiation oncology department's patient information form. A test revealed that the database was found to be efficient in managing patient information at each step. An important benefit of this database is improved efficiency in radiotherapy management. Information on patients who received radiotherapy is stored in a database. This means that this clinical data can be found easily and used in future, which will be helpful in research studies on the radiation oncology department. Benefits such as these will potentially contribute to improved radiotherapy quality.

• 한국발생생물학회지:발생과생식
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• 제15권3호
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• pp.205-213
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• 2011

Ethanol treatment during the brain growth spurt period has been known to induce the death of Purkinje cells. The underlying molecular mechanisms and the role of reactive oxygen species (ROS) in triggering ethanol-induced Purkinje cell death are, however, largely unresolved. We undertook TUNEL staining, western blotting assay and immunohistochemistry for the cleaved forms of caspase-3 and -9, with calbindin D28K double immunostaining to identify apoptotic Purkinje cells. The possibility of ROS-induced Purkinje cell death was immunohistochemically determined by using anti-8-hydroxy-2'deoxyguanosine (8-OHdG), a specific cellular marker for oxidative damage. The results show that Purkinje cell death of PD 5 rat cerebellum following ethanol administration is mediated by the activation of caspase-3 and -9. However, unexpectedly, TUNEL staining did not reveal any positive Purkinje cells while there were some TUNEL-positive cells in the internal and external granular layer. 8-OHdG was detected in the Purkinje cell layers at 8 h, peaked at 12-24 h, but not at 30 h post-ethanol treatment. No 8-0HdG immunoreactive cells were detected in the internal and external granular layer. The lobule specific 8-OHdG staining patterns following ethanol exposure are consistent with that of ethanol-induced Purkinje cell loss. Thus, we suggest that ethanol-induced Purkinje cell death may not occur by the classical apoptotic pathway and oxidative damage is involved in ethanol-induced Purkinje cell death in the developing cerebellum.

• 한국기술사회:학술대회논문집
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• 한국기술사회 1986년도 한일기술사 합동 심포지움
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• pp.60-65
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• 1986

기술혁신의 물결은 크게 일본의 산업계로 불어닥치고 있으며, 종래와 같은 공학계만의 학과로서는 당할 길이 없을 만큼 기술영역의 기술업무가 주요부분을 점유할 것으로 예측된다. 기술이전을 원활화시키기 위해서는 기술이전의 각 단계에서 각각의 과학기술인재가 유효하게 활용되어야할 필요가 더욱 중요하게 된다. 산업기술의 이전에는 민간기술자의 유효한 활용이 불가결한 것이며, 민간기술용역이 중요시되고 있는 것이다. 선단기술의 개발은 일본에서는 석유파동이래 상품혁신시대로 접어들어 기존의 기술진행에 대한 작은 기술개선이 생산성향상과 직결되고 있는 점을 중요시해야 할 것이다. 필자는 기술사로서 경험한 기술개발의 사례에서 산업고고학의 필요성을 통감한 것이다. 지녹기술의 개발수법을 연구하고 그 사례를 들어 기술사로서의 역할을 말한바 있다. 더욱 일본정부가 실시하고 있는 공업기술이전연구소의 계획실적에 언급하고 나아가서는 한국에 대한 의견을 말하고 고도한 기술도입에 따른 체제와 기술사의 적임에 관해서 조언하고 싶다.

• 디자인학연구
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• 제18권2호
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• pp.133-142
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• 2005

최근 온라인상의 사용자는 정형화된 패턴에서 벗어난 이미지와 감각을 선호하며 즉각적이고 상호 교환적인 형태를 요구한다. 온라인 상에서 시각적으로 자신을 알릴 수 있는 또 하나의 명함인 아바타의 사용이 증가하면서 1차적 형태의 아바타가 아닌 사용에 맞는 다양한 아바타 개발이 요구되는 것이 이러한 이유 일 것이다. 게임포털사이트 중 최근 가장 많은 인기를 끄는 포커, 고스톱 류의 온라인 카드 게임 아바타는 일반 커뮤니티 사이트의 아바타와 별반 다르게 사용되어 있지 않아 감성적이고 다양성을 요구하는 사용자를 만족시켜주고 있지 않다. 본 연구는 온라인 카드게임에 적합한 아바타의 활용형태를 제시하기 위해 먼저 기존 게임포털사이트에 나타난 카드게임 아바타 서비스와 이용자의 특성과 욕구를 분석하였다. 또한 설문조사를 통해 사용자들의 카드 게임 아바타 인지도, 디자인선호도를 읽어냄으로써 이용자욕구에 충실한 서비스 안을 가이드라인 하고자 하였다.

• 대한수학교육학회지:학교수학
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• 제13권2호
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• pp.323-343
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• 2011

2011 교육과정 개정 시안연구에서는 중학교 수준의 함수는 현실 세계의 상황을 이해하는 도구로서 초점을 맞추고, 중학교에서의 함수를 토대로 고등학교 함수에서 여러 영역을 통합하는 아이디어로서의 대응의 관점에서 정의된 형식화된 함수 개념으로 확장하는 것을 제안하고 있다. 교육과정을 개정할 때에 국제적 표준 교육과정과도 발맞추기 위하여 다른 나라의 상황을 고려하지 않을 수 없다. 본고에서는 독일에서의 함수 도입과 교수학습 측면에서의 특징을 살펴보기 위하여 독일의 여러 학교 형태 중 우리나라의 교육제도와 비슷한 학교 형태인 게잠트슐레(Gesamtschule, 종합학교)의 교과서를 선택하여 우리나라의 교과서와 비교 분석하였다. 함수영역을 중심으로 우리나라의 교과서의 구조적인 부분인 체제와 내용을 비교 분석한 결과, 독일 교과서에서는 함수 개념 도입과 내용 전개 방식, 그래프의 지도 방식 등에서 2007년 개정 교육과정과는 차이점을 보였다. 이는 우리나라의 개정 교육 과정 및 교과서의 개발에 참고가 될 만한 자료를 제공할 수 있을 것이라 기대한다.

• 패션비즈니스
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• 제21권4호
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• pp.127-143
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• 2017

In this study, we examine a variety of influences in the field of design and analysis about the value of visual tactile design. In hair design, through study on visual tactility, creative design inspiration in the field of hair design enables development of quality research. Research methods use Internet publications such as local and foreign data, analysis, and related research and book forms, such as network searches. library goes for consideration by a literature search. Contents of this study used review of the case and by visual tactility design, for this study, expressive characteristics by color, texture and form of hair design, from 2014-2017 trend shown in the last three years the expressions of visual tactility being used through the analysis of design by date of the case. Result of this study is, visual tactile design appearing in the areas of hair design, that are not of the rules that are active, abstract form, texture, described as a visual feel the promotion of effective, and light and high brightness is sweet tactile impression, high saturation was cold, dark color was hard and heavy, red system is warm and the blue system is cold sense. In general, design trend in hair for three years from 2014-2017, visual tactility in 2014 is a high saturation and unstructured also soft and bright colors. 2015 is on the overall shape, color, texture, hybrid design configuration is more. As of 2016, 2017 is curved and straight texture, appearance of the hybrid mix to maximize the visual tactility.

• Structural Engineering and Mechanics
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• 제28권2호
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• pp.129-152
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• 2008

This paper considers the solution of the stochastic differential equations (SDEs) with random operator and/or random excitation using the spectral SFEM. The random system parameters (involved in the operator) and the random excitations are modeled as second order stochastic processes defined only by their means and covariance functions. All random fields dealt with in this paper are continuous and do not have known explicit forms dependent on the spatial dimension. This fact makes the usage of the finite element (FE) analysis be difficult. Relying on the spectral properties of the covariance function, the Karhunen-Loeve expansion is used to represent these processes to overcome this difficulty. Then, a spectral approximation for the stochastic response (solution) of the SDE is obtained based on the implementation of the concept of generalized inverse defined by the Neumann expansion. This leads to an explicit expression for the solution process as a multivariate polynomial functional of a set of uncorrelated random variables that enables us to compute the statistical moments of the solution vector. To check the validity of this method, two applications are introduced which are, randomly loaded simply supported reinforced concrete beam and reinforced concrete cantilever beam with random bending rigidity. Finally, a more general application, randomly loaded simply supported reinforced concrete beam with random bending rigidity, is presented to illustrate the method.

• Environmental Analysis Health and Toxicology
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• 제30권
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• pp.7.1-7.7
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• 2015

Objectives The widely promising applications of graphene nanomaterials raise considerable concerns regarding their environmental and human health risk assessment. The aim of the current study was to evaluate the toxicity profiling of graphene family nanano-materials (GFNs) in alternative in vitro and in vivo toxicity testing models. Methods The GFNs used in this study are graphene nanoplatelets ([GNPs]-pristine, carboxylate [COOH] and amide [$NH_2$]) and graphene oxides (single layer [SLGO] and few layers [FLGO]). The human bronchial epithelial cells (Beas2B cells) as in vitro system and the nematode Caenorhabditis elegans as in vivo system were used to profile the toxicity response of GFNs. Cytotoxicity assays, colony formation assay for cellular toxicity and reproduction potentiality in C. elegans were used as end points to evaluate the GFNs' toxicity. Results In general, GNPs exhibited higher toxicity than GOs in Beas2B cells, and among the GNPs the order of toxicity was pristine > $NH_2$ > COOH. Although the order of toxicity of the GNPs was maintained in C. elegans reproductive toxicity, but GOs were found to be more toxic in the worms than GNPs. In both systems, SLGO exhibited profoundly greater dose dependency than FLGO. The possible reason of their differential toxicity lay in their distinctive physicochemical characteristics and agglomeration behavior in the exposure media. Conclusions The present study revealed that the toxicity of GFNs is dependent on the graphene nanomaterial's physical forms, surface functionalizations, number of layers, dose, time of exposure and obviously, on the alternative model systems used for toxicity assessment.

• 한국농공학회지
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• 제44권3호
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• pp.92-100
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• 2002

The advent or high-strength steel has enabled the arch structures to be relatively light, durable and long-spanned by reducing the cross sectional area. On the other hand, the possibility of collapse may be increased due to the slender members which may cause the stability problems. The limit analysis to estimate the ultimate load is based on the concept of collapse mechanism that forms the plastic zone through the full transverse sections. So, it is not appropriate to apply it directly to the instability analysis of arch structures that are composed with compressive members. The objective of this study is to evaluate the ultimate load carrying capacity of the parabolic arch by using the elasto-plastic finite element model. As the rise to span ratio (h/L) varies from 0.0 to 0.5 with the increment of 0.05, the ultimate load has been calculated fur arch structures subjected to uniformly distributed vertical loads. Also, the disco-elasto-plastic analysis has been carried out to find the duration time until the behavior of arch begins to show the stable state when the estimated ultimate load is applied. It may be noted that the maximum ultimate lead of the parabolic arch occurs at h/L=0.2, and the appropriate ratio can be recommended between 0.2 and 0.3. Moreover, it is shown that the circular arch may be more suitable when the h/L ratio is less than 0.2, however, the parabolic arch can be suggested when the h/L ratio is greater than 0.3. The ultimate load carrying capacity of parabolic arch can be estimated by the well-known formula of kEI/L$^3$where the values of k have been reported in this study. In addition, there is no general tendency to obtain the duration time of arch structures subjected to the ultimate load in order to reach the steady state. Merely, it is observed that the duration time is the shortest when the h/L ratio is 0.1, and the longest when the h/L ratio is 0.2.

• 한국콘텐츠학회논문지
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• 제15권8호
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• pp.77-84
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• 2015

디지털 사이니지는 우리가 다니는 길, 지하철, 실내공간 등 곳곳에서 다양한 형태로 설치되어 홍보, 정보제공, 아트, 게임의 역할을 담당하고 있다. 관련 연구 역시 디지털 사이니지 구현 기술과 산업적 현황 및 전망에 대부분 초점이 맞춰져 있다. 그에 반해, 디지털 사이니지의 공간성에 관한 연구는 미미한 편이고, 또한 디지털 사이니지가 공간에 들어서기 전과 후는 그곳에 있는 사람들의 공간에 대한 인식이 다르다는 점에서 연구의 필요성이 있다고 판단하여 본 연구를 진행하였다. 연구는 먼저 디지털 사이니지를 이해하기 위하여 개념, 유형, 종류에 관하여 살펴보고, 이어서 공간성에 관한 일반적인 이론을 고찰한 다음 디지털사이니지의 공간성을 혼종성, 생동성, 이동성, 유연성, 우연성의 5가지로 파악하여 그 특성을 제시하였다. 결론에서는 디지털 사이니지가 트랜스액티브한 공간이므로, 미디어에 따른 공간인식의 변화와 지속적 연구가 필요함을 밝혔다.