• Title/Summary/Keyword: gamma radiation

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Antibacterial Effect of PVP/PEG/Carrageenan/Silver Acetate Hydrogels by γ-ray (γ-ray를 이용하여 합성한 PVP/PEG/Carrageenan/Silver acetate 하이드로겔의 항균효과)

  • Lim, Youn-Mook;Youn, Young;Gwon, Hui-Jeong;Park, Jong-Seok;Nho, Young-Chang
    • Journal of Radiation Industry
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    • v.4 no.1
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    • pp.73-77
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    • 2010
  • In recent day, there is much interest in the biocidal activity of silver since silver is known to be safe and effective as disinifectant and biocidal material against coliforms and viruses. In this study, hydrogels containing silver acetate as antibacterial agent have been prepared using gamma rays irradiation. The hydrogels are composed of poly(vinyl pyrrolidone) (PVP), poly(ethylene glycol) (PEG), carrageenan and silver acetate. The concentration of solution was 9 wt%. The ratio of PVP : PEG : carrageenan was 6 : 1 : 2. The concentration of the silver acetate were 0, 0.01, 0.03, 0.05 and 0.07% and Gamma irradiation dose was 25 kGy. The Gamma irradiation dose in hydrogels with 0.01% silver acetate were 20 kGy, 35 kGy, 50 kGy, 65 kGy, and 80 kGy. The results showed that 0.01% silver acetate concentration of hydrogels by 25 kGy irradiation dose showed the highest antibacterial activity against E. coli and Staphylococcus aureus. Moreover, antibacterial activity of various Gamma irradiation dose in hydrogels treated 0.01% silver acetate showed highest 35 kGy irradiation dose against Staphylococcus aureus.

Microbiological and Sensory Characteristics of Gamma-irradiated Frozen Bibimbap (감마선 조사 냉동비빔밥의 미생물 및 관능적 품질특성)

  • Park, Jae-Nam;Song, Beom-Seok;Yoon, Young-Min;Choi, Soo-Jeong;Park, Jong-Heum;Kim, Jae-Kyung;Byun, Eui-Baek;Lee, Ju-Woon;Han, In-Jun;Sohn, Hee-Sook;Kim, Jae-Hun
    • Journal of Radiation Industry
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    • v.7 no.2_3
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    • pp.93-99
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    • 2013
  • This study was conducted to evaluate the effect of gamma irradiation on the microbiological and sensory characteristics of frozen Bibimbap. Frozen Bibimbap vegetables were contaminated by microbial levels of $2.70{\sim}6.67log\;CFU\;g^{-1}$ in total aerobic bacteria. Frozen Bibimbap was contaminated by microbial levels of $4.8log\;CFU\;g^{-1}$ in total aerobic bacteria, but microorganisms in gamma-irradiated samples at above 25 kGy were not found at detection limit less then $1log\;CFUg^{-1}$. Sensory characteristics of the gamma-irradiated Bibimbap were decreased depending upon the irradiation dose, and sensory scores of the samples irradiated with doses higher than 10 kGy were significantly decreased. Therefore, the application of combination of the various food processing technology should be considered for the sterilization of Bibimbap, without any deterioration of quality occurred by high dose irradiation.

Recent Development in Low Dose Nuclear Medicine Gamma Camera Imaging (저선량 핵의학 감마카메라 영상장치의 최근 발전)

  • Hwang, Kyung Hoon;Lee, Byeong-il;Kim, Yongkwon;Lee, Haejun;Sun, Yong Han
    • Journal of Biomedical Engineering Research
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    • v.36 no.4
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    • pp.123-127
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    • 2015
  • Recently, new gamma camera systems enabling low radiation dose imaging have been developed. We reviewed the recent development of these low dose gamma camera systems including high sensitivity detectors, device structures, noise reduction filters, efficient image reconstruction algorithms, low dose protocols, and so on. It is expected that further technological advances reduce both radiation dose and imaging time in gamma camera imaging especially for radiation-sensitive patients such as pediatric patients.

Comparison of Irradiation Effect of Different Radiation Types on Decontamination of Microorganisms in Red Pepper Powder (고춧가루 오염 미생물의 제어에서 방사선종별 조사 효과)

  • Park, Kyung-Sook
    • Journal of Radiation Industry
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    • v.8 no.1
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    • pp.1-5
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    • 2014
  • This study investigated the reduction of microbial population and sensory properties in red pepper powders irradiated by gamma ray, electron beam, and X-ray. Populations of total aerobic bacteria and yeast & molds in red pepper powders were decreased by irradiation treatment in a dose-dependent manner. Gamma ray, electron beam, and X-ray at doses above 8 kGy caused 100% inhibition on growth of aerobic bacteria in red pepper powders. Inhibitory activity of X-ray on sterilization of red pepper powders was significantly equal to or higher compared to gamma ray and electron beam. Color and off flavor in red pepper powders were no significant difference among the control and samples irradiated with gamma ray, electron beam, and X-ray. As a result, the gamma ray, electron beam, and X-ray irradiation can be used to sterilize the microbial growth in red pepper powders without quality loss.

Effect of Low Dose of Gamma Radiation on the Growth of Groundnut (Arachis hypogaea L.) (저선량 감마선이 땅콩 생장에 미치는 효과)

  • 김재성;이은경;백명화;박홍숙;김광호
    • Korean Journal of Environmental Biology
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    • v.17 no.3
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    • pp.257-261
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    • 1999
  • Effect of low dose gamma radiation on the growth of groundnut (Arachis hypognea L.) were investigated with respect to germination rate, seedling development and yield. Seeds of “Palpal” cultivar were irradiated with 0.5~20 Gy of ${\gamma}$ radiation in order to determine the hermetic effect of low dose radiation. The germination rate of ${\gamma}$-ray irradiation group was lower than that of the control but the seedling height of groundnut grown from seeds irradiated with low dose ${\gamma}$-ray was slightly higher than that of the control. The number of pod and kernels, and the seed yield increased by 27%, 17% and 19 %, respectively, in the 12.0 Gy irradiation group compared to that in the control group. The 100 seed weight was 87.2 g in the 4.0 Gy irradiation group, which was 11% heavier than 78.3 g in the control group. Low dose radiation showed an enhancement effects on the growth and yield components of groundnut.

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Three-dimensional dose reconstruction-based pretreatment dosimetric verification in volumetric modulated arc therapy for prostate cancer

  • Jeong, Yuri;Oh, Jeong Geun;Kang, Jeong Ku;Moon, Sun Rock;Lee, Kang Kyoo
    • Radiation Oncology Journal
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    • v.38 no.1
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    • pp.60-67
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    • 2020
  • Purpose: We performed three-dimensional (3D) dose reconstruction-based pretreatment verification to evaluate gamma analysis acceptance criteria in volumetric modulated arc therapy (VMAT) for prostate cancer. Materials and Methods: Pretreatment verification for 28 VMAT plans for prostate cancer was performed using the COMPASS system with a dolphin detector. The 3D reconstructed dose distribution of the treatment planning system calculation (TC) was compared with that of COMPASS independent calculation (CC) and COMPASS reconstruction from the dolphin detector measurement (CR). Gamma results (gamma failure rate and average gamma value [GFR and γAvg]) and dose-volume histogram (DVH) deviations, 98%, 2% and mean dose-volume difference (DD98%, DD2% and DDmean), were evaluated. Gamma analyses were performed with two acceptance criteria, 2%/2 mm and 3%/3 mm. Results: The GFR in 2%/2 mm criteria were less than 8%, and those in 3%/3 mm criteria were less than 1% for all structures in comparisons between TC, CC, and CR. In the comparison between TC and CR, GFR and γAvg in 2%/2 mm criteria were significantly higher than those in 3%/3 mm criteria. The DVH deviations were within 2%, except for DDmean (%) for rectum and bladder. Conclusions: The 3%/3 mm criteria were not strict enough to identify any discrepancies between planned and measured doses, and DVH deviations were less than 2% in most parameters. Therefore, gamma criteria of 2%/2 mm and DVH related parameters could be a useful tool for pretreatment verification for VMAT in prostate cancer.

Effect of Gamma Irradiation on the Structural and Physiological Properties of Silk Fibroin

  • Sung, Nak-Yun;Byun, Eui-Baek;Kwon, Sun-Kyu;Kim, Jae-Hun;Song, Beom-Seok;Choi, Jong-Il;Kim, Jin-Kyu;Yoon, Yo-Han;Byun, Myung-Woo;Kim, Mee-Ree;Yoo, Hong-Sun;Lee, Ju-Woon
    • Food Science and Biotechnology
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    • v.18 no.1
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    • pp.228-233
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    • 2009
  • This study was conducted to examine the changes in the molecular structure and physiological activities of silk fibroin by gamma irradiation. The results of gel permeation chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed that the molecular weight of fibroin was increased depending upon the irradiation dose. Secondary structure of fibroin determined by using circular dichroism revealed that the ratio of $\alpha$-helix was increased up to 10 kGy and then decreased depending upon the irradiation dose. Whereas, the ratio of $\beta$-sheet, $\beta$-turn, and random coil were decreased and then increased with an alteration in the $\alpha$-helix secondary conformation. The 2.2-diphenyl-1-picryl-hydrazil (DPPH) radical scavenging activity of fibroin was increased by gamma irradiation at 5 kGy, but was decreased above 10 kGy depending upon the irradiation dose. Also, the inhibition activities of tyrosinase and melanin synthesis of fibroin were increased by gamma irradiation. These results indicated that gamma irradiation could be used as an efficient method to make fibroin more suitable for the development of functional foods and cosmetics.

DNA Double-Strand Breaks Serve as a Major Factor for the Expression of Arabidopsis Argonaute 2

  • Lee, Sungbeom;Chung, Moon-Soo;Lee, Gun Woong;Chung, Byung Yeoup
    • Journal of Radiation Industry
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    • v.10 no.4
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    • pp.243-248
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    • 2016
  • Argonaute 2 (AtAGO2) is a well characterized effector protein in Arabidopsis for its functionalities associated with DNA double-strand break (DSB)-induced small RNAs (diRNAs) and for its inducible expression upon ${\gamma}$-irradiation. However, its transcriptional regulation depending on the recovery time after the irradiation and on the specific response to DSBs has been poorly understood. We analyzed the 1,313 bp promoter sequence of the AtAGO2 gene ($1.3kb_{pro}$) to characterize the transcriptional regulation of AtAGO2 at various recovery times after ${\gamma}$-irradiation. A stable transformant harboring $1.3kb_{pro}$ fused with GUS gene showed that the AtAGO2 is highly expressed in response to ${\gamma}$-irradiation, after which the expression of the gene is gradually decreased until 5 days of DNA damage recovery. We also confirm that the AtAGO2 expression patterns are similar to that of ${\gamma}$-irradiation after the treatments of radiomimetic genotoxins (bleomycin and zeocin). However, methyl methanesulfonate and mitomycin C, which are associated with the inhibition of DNA replication, do not induce the expression of the AtAGO2, suggesting that the expression of the AtAGO2 is closely related with DNA DSBs rather than DNA replication.

Surface Graft Polymerization of Poly(ethylene glycol) Methacrylate onto Kenaf Pulp using Gamma-ray Irradiation (감마선을 이용한 케나프 펄프 표면의 Poly(ethylene glycol) Methacrylate 그라프트 중합반응)

  • Oh, Doori;Jeun, Joon Pyo;Kang, Phil Hyun
    • Journal of Radiation Industry
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    • v.6 no.3
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    • pp.251-255
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    • 2012
  • Pulp is typically used for paper industry to manufacturing various types of papers. However simply chemical modification makes enable the pulp to a wide range of application in various industrial fields. To bring the polymerization the gamma ray irradiated on the mixture of kenaf and PEGMA in various dose ranges from 20 to 60 kGy. As a results, the graft degree of 20.0% was obtained from 475 g of gamma ray irradiated pulp and PEGMA. After the polymerization, the chemical structure and morphology of the surfaces were examined by Fourier transform infrared spectroscopy, thermogravimetric analysis, and scanning electron microscope. Chemical structure of grafted pulp has significantly growth in carbonyl content with increasing the radiation dose. Also surface morphology was distinctly changed with decreased the degree of roughness and increasing the diameter. These results were explained gamma ray irradiation improve performance of graft polymerization efficiency.

Study on Decomposition of Several Pesticides by Gamma-Irradiation (감마선 조사에 의한 농약 성분의 분해 연구)

  • Lee, Joo-Sang;Jung, Su-Yeon;Oh, Seung-Yeol;Jang, Beom-Su;Park, Sang Hyun
    • Journal of Radiation Industry
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    • v.6 no.3
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    • pp.205-209
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    • 2012
  • The decomposition of 50 pesticides present in an aqueous solution using ${\gamma}-irradiation$ from a $^{60}Co$ gamma-ray source was investigated using laboratory-scale experiment. The rates of decomposition were determined using a gas chromatography-electron capture detector (GC-ECD), high-performance liquid chromatography-photo diode array detector (HPLC-PDA), and HPLC-fluorescence detector (FLD). When the initial concentration of pesticides was 10 ppm, and the radiation dose was 2, 5, 10, 20, and 30 kGy, respectively, 14 pesticide samples showed high removal rates (>50%) at absorbed doses of more than 10 kGy. With the exception of procymidone, they were all completely removed at a 30 kGy irradiation dose. These results provide fundamental data on the reactivity between gamma-irradiation and pesticides in an aqueous solution. Further, an evaluation of the toxicity of radiolytic intermediate products is required.