• Genomics & Informatics
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• v.7 no.1
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• pp.32-37
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• 2009

The quality assurance (QA) is of utmost importance in biobanks when archived biomaterials are distributed to biomedical researchers. For sample authentication and cross-contamination detection, the two fundamental elements of QA, STR genotyping is usually utilized. However, the incorporated number of STR markers is highly redundant for biobanking purposes, resulting in time and cost inefficiency. An index to measure the cross-contamination detection capability of an STR marker, the mixture probability (MP), was developed. MP as well as other forensic parameters for STR markers was validated using STR genotyping data on 2328 normal Koreans with the commercial AmpFlSTR kit. For Koreans, 7 STR marker (D2S1338, FGA, D18S51, D8S1179, D13S317, D21S11, vWA) set was sufficient to provide discrimination power of ${\sim}10^{-10}$ and cross-contamination detection probability of ${sim}1$. Interestingly, similar marker sets were obtained from African Americans, Caucasian Americans, and Hispanic Americans under the same level of discrimination power. Only a small subset of commonly used STR markers is sufficient for QA purposes in biobanks. A procedure for selecting optimal STR markers is outlined using STR genotyping results from normal Korean population.

• Genomics & Informatics
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• v.11 no.2
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• pp.83-92
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• 2013

Genetic studies on facial morphology targeting healthy populations are fundamental in understanding the specific genetic influences involved; yet, most studies to date, if not all, have been focused on congenital diseases accompanied by facial anomalies. To study the specific genetic cues determining facial morphology, we estimated familial correlations and heritabilities of 14 facial measurements and 3 latent factors inferred from a factor analysis in a subset of the Korean population. The study included a total of 229 individuals from 38 families. We evaluated a total of 14 facial measurements using 2D digital photographs. We performed factor analysis to infer common latent variables. The heritabilities of 13 facial measurements were statistically significant (p < 0.05) and ranged from 0.25 to 0.61. Of these, the heritability of intercanthal width in the orbital region was found to be the highest ($h^2$ = 0.61, SE = 0.14). Three factors (lower face portion, orbital region, and vertical length) were obtained through factor analysis, where the heritability values ranged from 0.45 to 0.55. The heritability values for each factor were higher than the mean heritability value of individual original measurements. We have confirmed the genetic influence on facial anthropometric traits and suggest a potential way to categorize and analyze the facial portions into different groups.

• The Korean Journal of Health Service Management
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• v.5 no.2
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• pp.173-186
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• 2011

The purpose of this study was to know dysfunctions degree, daily living activity, depression and quality of life among stroke elderly person; and to know what kind of factors affecting to quality of life of the stroke elderly person; after that provide a fundamental data to nursing arbitration plan about increase height quality of life of the stroke elderly person. The study subjects were collected 119 people, over than 60 age, who were diagnosed with stoke in D hospital, living in B city. The data was collected by using personal interviews and questionnaire, from Nov 2008 to Jan 2009. The questionnaire were Pre-Stroke MRDS(Modified Rankin Disability Scale), Barthel-ADL(Activities of Daily Living), K-IADL(Korean-Instrumental Activities of Daily Living), GDS-15(Geriatric Depression Scale-15-question form) methods. The pre-stroke MRDS was appeared a functional obstacle. The mean score of activity of daily living was 18.24 which showed the subjects were mildly disabled, the score of instrumental activities of daily living was 7.94 which showed the mildly abled, and score of depressiveness was 7.41 which showed the subjects were mildly depression. There was a significantly correlation among MRDS, ADL, IADL, depressiveness and quality of life. Through these study result, important to check the old subjects' depressiveness, cognitive functions, daily living abilities, dysfunctions degree to main tain their quality of life.

• Journal of The Korean Association of Information Education
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• v.25 no.2
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• pp.265-277
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• 2021

With the development of technology, the concept of digital literacy is expanding from the focus of function and tool utilization to the extent of communication and participation in social and cultural contexts. In particular, learners' digital literacy capabilities are more important and necessary in remote learning environments such as Corona19. In this study, we studied how to improve digital literacy education through analysis and inspection of digital literacy shown in elementary school textbooks. To this end, we analyze it through compliance consisting of 8 fundamental pieces of knowledge, 20 sub technical skills, and 10 keys of competencies that constitute digital literacy. As a result of the study, the contents of digital literacy education in elementary school textbooks were presented centered on functions and tools, and as they were biased in certain areas, they were found to be lacking in systematicity and connectivity. Therefore, it proposed the composition of the curriculum system of digital literacy through the independence of elementary informatics curriculum, the specific composition of curriculum, and the strengthening of pre-service teachers' practical skills.

• Phonetics and Speech Sciences
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• v.14 no.2
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• pp.39-54
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• 2022

This study aims to clarify the prosodic differences in speech types by examining the Korean read speech and spontaneous speech in the Korean part of the L2 Korean Speech Corpus (speech corpus for Korean as a foreign language). To this end, the articulation length, articulation speed, pause length and frequency, and the average fundamental frequency values of sentences were set as variables and analyzed via statistical methodologies (t-test, correlation analysis, and regression analysis). The results found that read speech and spontaneous speech were structurally different in the form of prosodic phrases constituting each sentence and that the prosodic elements differentiating each speech type were articulation length, pause length, and pause frequency. The statistical results show that the correlation between articulation speed and articulation length was highest in read speech, explaining that the longer a given sentence is, the faster the speaker speaks. In spontaneous speech, however, the relationship between the articulation length and the pause frequency in a sentence was high. Overall, spontaneous speech produces more pauses because short intonation phrases are continuously built to make a sentence, and as a result, the sentence gets lengthened.

• Journal of applied mathematics & informatics
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• v.41 no.1
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• pp.51-70
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• 2023

The flow of an incompressible Ellis fluid in an inclined asymmetric channel, driven by peristaltic waves was studied under low Reynolds number and long wavelength assumptions. The wave on each side of the channel are assumed to be an infinite train of sinusoidal waves, both having the same constant wave speed and wavelength however, they vary in wave amplitude, channel half width and phase angle. We derived expressions for the axial and transverse velocities, volume flow rate, pressure rise per unit wavelength and streamlines. The effects of varying the wave amplitudes, the phase angle, the channel width, the angle of inclination of the channel as well as the fluid parameters on the flow were analyzed. Trapping conditions were determined and the presence of reflux highlighted using the streamlines for the necessary channel and fluid conditions. By varying the fluid parameters, changes in the fluid that deviated from the Newtonian case resulted in a reduction in the axial velocity in the neighborhood of the center of the channel and a simultaneous increase in the velocity at the periphery of the channel. A nonlinear relation was observed with the pressure rise and the volume flow rate. This nonlinear relation is more pronounced with an increase in the absolute value of the volume flow rate. For Newtonian fluids a linear relation exists between these two variables. The fluid parameters had little effects on the streamlines. However, variations of the wave amplitudes, volume flow, channel width and phase angle had greater effects on the streamlines and hence the trapped region.

• Journal of Internet Computing and Services
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• v.17 no.5
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• pp.151-160
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• 2016

The purpose of this research is to investigate Korean popular attitudes and social perceptions of 'sharing economy' terminology at the current moment from a creative or socio-economic point of view. In Korea, this study discovers and interprets the objective and tangible annual changes and patterns of sociocultural collective intelligence that have taken place over the last five years by applying text mining in the big data analysis approach. By crawling and Googling, this study collected a significant amount of time series web meta-data with regard to the theme of the sharing economy on the world wide web from 2010 to 2014. Consequently, huge amounts of raw data concerning sharing economy are processed into the value-added meaningful 'word clouding' form of graphs or figures by using the function of word clouding with R programming. Till now, the lack of accumulated data or collective intelligence about sharing economy notwithstanding, it is worth nothing that this study carried out preliminary research on conducting a time-series big data analysis from the perspective of knowledge management and processing. Thus, the results of this study can be utilized as fundamental data to help understand the academic and industrial aspects of future sharing economy-related markets or consumer behavior.