• Title/Summary/Keyword: functional standard

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HPLC Validation of Valerian Ethanol Extract as a Functional Food (건강기능식품 원료로서 길초근 주정 추출물의 지표성분 분석법 검증)

  • Jo, Kyungae;Han, Sung Hee;Bae, Song-Hwan;Shin, Jung Cheul;Suh, Hyung Joo
    • The Korean Journal of Food And Nutrition
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    • v.31 no.1
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    • pp.104-108
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    • 2018
  • The purpose of this study was to establish valerenic acid as a marker compound for the standardization of ethanol extract of Valerinan officinalis (valerian) root as a functional health food. We established valerenic acid as a marker compound using HPLC. HPLC was used to quantify the marker compound in the valerian extract after validation of methods with linearity, accuracy, and precision. The specificity for retention time was met by comparative analysis of the valerian extract and standard compound using HPLC. The method showed high linearity of the calibration curve with a coefficient of correlation ($R^2$) of 0.9999. The limit of quantification (LOQ) was $10{\mu}g/mL$. The accuracy of measurement was 99.88~00.68% and the relative standard deviation (RSD) value was 0.59%. In addition, our analytical method yielded a 29% mean content of valerenic acid in the valerian ethanol extract. These results indicate that the established HPLC method facilitated the determination of marker compounds in the valerian extract for the standardization of health functional foods.

Construction and Functional Tests of Fuel Assembly Mechanical Characterization Test Facility (핵연료집합체 기계적특성 시험시설 구축과 기능시험)

  • Lee, Kang-Hee;Kang, Heung-Seok;Yoon, Kyung-Ho;Yang, Jae-Ho
    • Transactions of the Korean Society of Pressure Vessels and Piping
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    • v.12 no.1
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    • pp.11-16
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    • 2016
  • Fuel assembly's mechanical characterization test facility (FAMeCT) in KAERI was constructed with upgraded functional features such as increased loading capacity, underwater vibration testing and severe earthquake simulation for extended fuel design guideline. This facility is designed and developed to provide out-pile fuel data for accident analysis model and fuel licensing. Functional tests of FAMeCT were performed to confirm functionality, structural integrity, and validity of newly-built fuel assembly mechanical test facility. Test program includes signal check of data acquisition system, load delivering capacity using real-sized fuel assemblies and a standard loading cylindrical rigid specimen. Fuel assembly's lateral bending test was carried out up to 30 mm of pull-out displacement. Limit case axial compression loading test up to 33 kN was performed to check structural integrity of UCPS (Upper Core Plate Simulator) support frame. Test results show that all test equipment and measurement system have acceptable range of alignment, signal to noise ratio, load carrying capacity limit without loss of integrity. This paper introduces newly constructed fuel assembly's mechanical test facility and summarizes results of functional test for the mechanical test equipment and data acquisition system.

Clinical Application of Botulinum Toxin to Functional Dysphonia (기능성 음성장애에서 보툴리늄 독소의 임상적 적용)

  • Kim, Han Su
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.30 no.1
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    • pp.12-14
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    • 2019
  • Functional dysphonia (FD) is a disease entity which includes various voice disorders in the absence of structural or neurologic laryngeal pathology. Muscle tension dysphonia (MTD), psychogenic dysphonia are representative FD with completely different pathogenesis. Therefore there is no standard treatment modality for FD, the first step of treatment of FD is differentiating patient's voice symptoms from other organic voice disorders and other functional voice problems. MTD is a functional voice disorder caused by hyperfunction of intrinsic and extrinsic laryngeal musculature. Symptoms include increased vocal effort, roughness, fatigue and odynophonia. First line for MTD is indirect or direct voice therapy. Unfortunately, many patients with MTD improve with voice therapy alone. For these patients, various modalities tried; lidocaine application, surgical excision of the false vocal folds, and botulinum toxin injection, etc. Botulinum toxin injections are widely used in the field of otolaryngology, especially for spasmodic dysphonia. However, its use in FD or MTD has only been described in few case reports. The aim of this lecture is to evaluate the feasibility of botulinum toxin injection for FD, especially MTD.

Current Achievement and Perspectives of Seed Quality Evaluation in Soybean (콩 품질평가 현황과 전망)

  • 김용호
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.47
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    • pp.95-106
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    • 2002
  • Soybean is one of the most important sources of protein and oil in the world. Recently, emphasis has been laid on the chemical composition of soybean seeds for the processing soybean foods. Improvement of soybean components has been expected to improve food-processing quality for the processed soybean products such as soymilk and various edible ingredients as well as fur the traditional soyfoods. In Korea, soybean breeding research programmes have been focused on the quality of the products derived from soybean with yield stability, and some new modified soybean varieties haying good food-processing quality were developed recently. So the efforts of establishing standard and standardization of products in soybean are important. Three main categories should be considered in view of soybean seed quality; the marketing value such as grain size, shape, and appearance; the eating and processing value such as dehulled ratio, water absorption rate, and benny flavor; the nutritional value such as protein, lipid, and carbohydrate contents. And the new frontiers in research are looking at the functional nutrients in soybeans and how to improve them. In case marketing value, mainly the appearance is evaluated, therefore, each country has an application of standard related to quality. Each determination of standard class, heat-damaged kernels, splits, and soybeans of other colors is made on the basis of the grain when free from foreign materials. But processing value and nutritional value for standardization were not studied in detail till now. In addition, soybean has potential roles in the prevention and treatment of chronic diseases, most notably cancer, osteoporosis, and heart disease. The functional nutrients include a protease inhibitor, phytic acid, saponins, and isoflavones, etc.. It is believed that standardization of soybean quality should perform to overcome the difficulties, relatively high price of domestic soybean products has weakened the competitive power, in the market related to WTO. So, we should focus on further research into the evaluation and establishment of quality-standard in soybean.

A Case Study for the Reorganization of the Standard of Government Function Classification (BRM): Focusing on the 'Cultural Heritage' Policy Area (정부기능분류체계(BRM)의 재정비를 위한 사례연구 - '문화재' 정책영역을 중심으로 -)

  • Nam, Seo-jin;Yim, Jin-hee
    • Journal of Korean Society of Archives and Records Management
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    • v.17 no.2
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    • pp.129-163
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    • 2017
  • This study investigated the administrative history, from the introduction of the "Standard of Government Function Classification" (BRM) to its development and application. Through the results of the survey, the causes of the problems observed in the current government's functional classification system were revealed. The current survey examined the functional classification scheme of the central government and local governments on the "cultural heritage" policy area (9 major functions, 59 middle functions, 297 small functions, and 1,287 unit tasks). It confirmed the problem of the separation of functions between central and local governments as well as other problems. Among the problems, this study proposed an improvement model through four representative cases such as the "designation of cultural heritage." In order to reorganize the "Standard of Government Function Classification," it is necessary to design a business function with the reproduction of tasks, establish a system for management and operation in order to maintain the consistency of the business function, educate users, and suggest continuous improvement.

Evaluation of the Preservation Functions in Standard Records Management System for Public Agencies (표준 기록관리시스템의 전자기록 보존 기능 평가 연구 - 문서보존포맷변환 기능을 중심으로 -)

  • Hyun, Moonsoo
    • Journal of Korean Society of Archives and Records Management
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    • v.13 no.2
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    • pp.115-147
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    • 2013
  • This study evaluated the implementation of preservation functions and the degree of implementation in standard records management systems (SRMS) for public agencies. For evaluation, it identified digital preservation activities by analyzing legislation and standards for public records management, especially functional requirements for records management system. Compared to these, it pre-evaluated the functions that SRMS claims to be implemented. It was found that preservation functions implemented in SRMS mainly focuses on migration to standard format. A checklist was made based on the adjusted scope by reflecting the result of pre-evaluation and was distributed to record managers who work for public agencies. This study found that the preservation functions were relatively compliant with the functional requirement for records management system for public agencies, but the way of implementation hardly support records managers of public agencies. The preservation functions of SRMS must be improved or be reconsidered based on the results and further studies.

Functional Status and Development Direction of Standard Records Management System (표준기록관리시스템(RMS)의 기능 현황 및 발전방향 10년의 운영 경험과 기능 개선 사항을 중심으로)

  • Yu, Young Moon
    • The Korean Journal of Archival Studies
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    • no.57
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    • pp.235-279
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    • 2018
  • Electronic records produced by central administrative agencies are transferred to the National Archives of Korea. In the absence of defects or errors in electronic records, it is a proof that the government's electronic records management system is operating normally. Various problems have been found in this process, and there still remain problems to be solved. At the heart of it is a standard records management system, which has been continuously improved. In this paper, I introduce the functional improvement of the record management functions of the standard records management system. Among them, the important matters describe the background and reason for the improvement. In addition, the direction of development of the standard records management system was examined in terms of recognition conversion of recordkeepers, strengthen collaboration between recordkeepers and developers, improving records management metadata quality, linking related systems, automating records management, and IT environment change.

Development of Simultaneous Analysis of Ferulic Acid, Caffeic Acid, Catechin and Taxifolin from Health Functional Food Pinus Pinaster Bark Extract by UPLC-MS/MS (건강기능식품 프랑스해안송껍질추출물 중 UPLC-MS/MS를 이용한 Ferulic acid, Caffeic acid, Catechin, Taxifolin 동시분석법 개발 연구)

  • Oh, Jae-Myoung;Kim, Ji An;Hu, Soo Jung;Choi, Yoon Hee;Oh, Keum Soon
    • Journal of Food Hygiene and Safety
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    • v.34 no.5
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    • pp.431-437
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    • 2019
  • This study was conducted to develop a simultaneous analysis method for ferulic acid, caffeic acid, catechin and taxifolin from Health Functional Food (HFF) Pinus Pinaster bark extract. The simultaneous analytical method for ferulic acid, caffeic acid, catechin and taxifolin is carried out using UPLC-MS/MS. The method validation was performed to determine selectivity, linearity, accuracy, limit of detection (LOD), limit of quantification (LOQ) and precision for ferulic acid, caffeic acid, catechin and taxifolin. LC-MS/MS method was established using an Acquity UPLC BEH $C_{18}$ Column and was applied for these 4 compounds. Product-ion traces, at m/z $194.2{\rightarrow}133$, $180.2{\rightarrow}135$, $290.3{\rightarrow}245$, $304.3{\rightarrow}248$, were used for quantitative analysis of ferulic acid, caffeic acid, catechin and taxifolin, respectively. Excellent linearity ($r^2=0.999$) was observed for ferulic acid, caffeic acid, catechin and taxifolin in the concentration range (50-2500 mg/L). The observed recoveries of these 4 compounds were found to be between 84.9 and 104.9%, while precision was between 1.20 and 4.43% relative standard deviation (% RSD).

Functional Separation of Myoelectric Signal of Human Arm Movements Using Time Series Analysis (시계열 해석을 이용한 팔운동 근전신호의 기능분리)

  • 홍성우;남문현
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.41 no.9
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    • pp.1051-1059
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    • 1992
  • In this paper, two general methods using time-series analysis in the functional separation of the myoelectric signal of human arm movements are developed. Autocorrelation, covariance method and sequential least squares algorithm were used to determine the model parameters and the order of signal model to describe six arm movement patterns` the forearm flexion and extension, the wrist pronation and supination, rotation-in and rotation-out. The confidence interval to classify the functions of arm movement was defined by the mean and standard deviation of total squared error. With the error signals of autoregressive(AR) model, the result showed that the highest success rate was obtained in the case of 4th order, and success rate was decreased with increase of order. Autocorrelation was the method of choice for better success rate. This technique might be applied to biomedical and rehabilitation engineering.

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The problems and present production state of functional foods utilizing the medicinal herbs -rice, peanut, plums- (약용식물을 이용한 기능성 식품의 생산현황 및 과제 - 쌀, 땅콩, 매실 -)

  • Baek Hum Young
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2002.05a
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    • pp.73-76
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    • 2002
  • The foods such as rice, peanuts and plums etc. are recognized as a direct way to keep health and to cure diseases based on the theory of that the medicine and foods are from the same source, not just to maintain life, therefore due to this reason, the dietary treatment is currently gathering strength with patients who are suffering from chronic diseases. Especially, 1 trust that the practical application of functional foods and taking medicine must be highly effective in curing diseases or relieving symptoms. In order to produce the superior functional foods by medicinal herbs, we should to make a greater effort to research the harvest time of material, drying and keeping method, and additionally try to develop the standard of food material and various drugs manufacturing continually.

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