• Journal of Digital Convergence
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• v.20 no.1
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• pp.191-202
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• 2022

The purpose of this study is to examine the effect of a 10-week body stability exercise program, which was conducted on 24 male football players. The result of the Visual Response Speed Test using BlazePod, showed a significant increase of the upper arms, left foot and right foot for 15 second in number of reactions and reaction time (p<0.001). As a result of evaluating whether or not 7 functional movements were improved in order to evaluate the functional movement screen, Hurdle Step (p=0.001) and Active Straight Leg Rise (p=0.022) movements were significantly improved. significantly improved. As a result of measuring the y-balance Test in order to evaluate the balance ability, composite score(p<0.001) of both sides was significantly improved. The result of evaluating vital capacity, which was conducted to evaluate mobility and muscle endurance, showed a significant improvement in Forced vital capacity(p<0.001) and Forced expiratory volume in 1.0(p=0.003). In conclusion, a 10-week BSE program intervention in high school period, which can most improve the technical fitness necessary for the game in power, agility, leg strength, leg stability, mobility, and muscle endurance, will improve overall technical fitness, prevent football players from being injured and enhance their performance.

• PNF and Movement
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• v.6 no.2
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• pp.51-57
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• 2008

Purpose : Mechanical stress activates signaling cascades and leading to a specific response of a network of signaling pathways. The purpose of this study is to review the effect of mechanical stress-induced adaptation in skeletal muscle involves a biological mechanisms. Methods : This is literature study with Pubmed, Medline and books. Results : Skeletal muscle tissue demonstrates a malleability and may adjust its metabilic response, vascularization and neuromuscular characteristic makeup in response to alteration in functional demands. The adaptation in skeletal muscle involoves a multitude of signalling mechanisms related with insuline-like growth factor, vascular endothelial growth factor, neurotrophins. Conclusions : The identification of the basic relationships underlying the malleability of skeletal muscle tissue is likely to be of relevance for our understanding with PNF technique.

• Transactions of Materials Processing
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• v.10 no.6
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• pp.493-499
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• 2001

An optimal robust design methodology has been developed to minimize warpage in injection-molded pats. The response surface methodology was applied to obtain a functional relationship between design variables and warpage value, and the modified complex method was used as an optimization tool to search for an optimal design solution over prescribed design region. To attain robustness against process variations, Taguchi's SN ratio was introduced as the design metric. The proposed optimal design procedure was applied to an actual part, the Guide-ASF model of a fax machine, and the usefulness of the methodology was shown through the CAE simulation using a commercial injection molding software package.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2009.04a
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• pp.616-620
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• 2009

Modern wind turbines have been mainly erected in region where earthquake are rare or normally weak, especially Korea was thought as safety zone from earthquake. But recently, the earthquake occurs more and more frequently. So, the wind turbine design is required the structural and functional stability under the earthquake. The earthquake can influence normal operation, even if a weak earthquake. There are two ways to review the design under earthquake using Computer Applied Engineering (CAE). One is the Response Spectrum Analysis (RSA) the other is Time History Analysis (THA). In this research, dynamic response on time is obtained under the earthquake by taking into account ground accelerogram consistent with the relevant standards applied to the turbine foundation.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.12
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• pp.5947-5954
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• 2012

The cancer stem cell (CSC) model states that cancers are organized in cellular hierarchies, which explains the functional heterogeneity often seen in tumors. Like normal tissue stem cells, CSCs are capable of self-renewal, either by symmetric or asymmetric cell division, and have the exclusive ability to reproduce malignant tumors indefinitely. Current systemic cancer therapies frequently fail to eliminate advanced tumors, which may be due to their inability to effectively target CSC populations. It has been shown that embryonic pathways such as Wnt, Hedgehog, and Notch control self-renewal and cell fate decisions of stem cells and progenitor cells. These are evolutionary conserved pathways, involved in CSC maintenance. Targeting these pathways may be effective in eradicating CSCs and preventing chemotherapy or radiotherapy resistance.

• Journal of Korean Society for Quality Management
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• v.23 no.3
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• pp.84-92
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• 1995

A method is proposed for the simultaneous optimization of several response functions that depend on the same set of controllable variables and are adequately represented by a response surface model (polynomial regression model) with the same degree and with constraint that the individual responses have the target values. First, the multiple responses data are checked for linear dependencies among the responses by eigenvalue analysis. Thus a set of responses with no linear functional relationships is used in developing a function that measures the distance estimated responses from the target values. We choose the optimal condition that minimizes this measure. Also, under the different degree of importance two step procedures are proposed.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.18 no.4
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• pp.317-335
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• 2014

In this work, we investigate the global stability analysis of a viral infection model with antibody immune response. The incidence rate is given by a general function of the populations of the uninfected target cells, infected cells and free viruses. The model has been incorporated with two types of intracellular distributed time delays to describe the time required for viral contacting an uninfected cell and releasing new infectious viruses. We have established a set of conditions on the general incidence rate function and determined two threshold parameters $R_0$ (the basic infection reproduction number) and $R_1$ (the antibody immune response activation number) which are sufficient to determine the global dynamics of the model. The global asymptotic stability of the equilibria of the model has been proven by using Lyapunov theory and applying LaSalle's invariance principle.

• Molecules and Cells
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• v.25 no.4
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• pp.553-558
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• 2008

Essential aspects of the innate immune response to microbial infection appear to be conserved between insects and mammals. In order to identify new Drosophila melanogaster genes involved in the immune response, we performed gene expression profiling of Drosophila SL2 cells stimulated with bacterial (LPS/PGN) or fungal (curdlan) components using a cDNA microarray that contained 5,405 Drosophila cDNAs. We found that some genes were similarly regulated by LPS/PGN and curdlan. However, a large number, belonging to the functional classes of cell organization, development, signal transduction, morphogenesis, cell cycle, and DNA replication, displayed significant differences in their transcription profiles between the two treatments, demonstrating that bacterial and fungal components induce different immune response even in an in vitro cell system.

• Smart Structures and Systems
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• v.15 no.5
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• pp.1177-1202
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• 2015

The present paper is concerned with the optimal control and/or design of symmetric and antisymmetric composite laminate with two piezoelectric layers bonded to the opposite surfaces of the laminate, and placed symmetrically with respect to the middle plane. For the optimal control problem, Liapunov-Bellman theory is used to minimize the dynamic response of the laminate. The dynamic response of the laminate comprises a weight sum of the control objective (the total vibrational energy) and a penalty functional including the control force. Simultaneously with the active control, thicknesses and the orientation angles of layers are taken as design variables to achieve optimum design. The formulation is based on various plate theories for various boundary conditions. Explicit solutions for the control function and controlled deflections are obtained in forms of double series. Numerical results are given to demonstrate the effectiveness of the proposed control and design mechanism, and to investigate the effects of various laminate parameters on the control and design process.

• Mycobiology
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• v.39 no.4
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• pp.249-256
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• 2011

Microorganisms are significantly affected when the ambient pH of their environment changes. They must therefore be able to sense and respond to these changes in order to survive. Previous investigators have studied various fungal species to define conserved pH-responsive signaling pathways. One of these pathways, known as the Pal/Rim pathway, is activated in response to alkaline pH signals, ultimately targeting the PacC/Rim101 transcription factor. Although the central signaling components are conserved among divergent filamentous and yeast-like fungi, there is some degree of signaling specificity between fungal species. This specificity exists primarily in the downstream transcriptional targets of this pathway, likely allowing differential adaptation to species-specific environmental niches. In this review, the role of the Pal/Rim pathway in fungal pH response is discussed. Also highlighted are functional differences present in this pathway among human fungal pathogens, differences that allow these specialized microorganisms to survive in the various micro-environments of the infected human host.