• International Journal of Costume and Fashion
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• 제18권2호
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• pp.45-64
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• 2018

This study assessed scuba divers' wetsuit selection criteria based on the gender, age and scuba diving commitment level along with identifying currently owned and preferred wetsuit types. Lamb and Kallal's Functional, Expressive, and Aesthetic Consumer Needs (FEA) Model was the conceptual framework used for this study. Scuba diving has seen consistent growth, worldwide, it is necessary to investigate with wetsuit needs of this consumer group. A survey of 302 active scuba divers participated in the study. Total participants included 202 male and 100 female scuba divers. Divers stated fit was the most highly rated criteria with don/doff being most problematic. Female and older divers regarded functional performance criterion greatly(p<.05). Highly committed divers regarded the functional quality (p<.01) and aesthetic/expressive features (p<.05) of the wetsuit as important and owned more wetsuits(p<.01). Gender saw differences in required sizes ranges(p<.001) and style preferences(p<.05). Results suggest gender, age, and commitment levels all impact the wetsuit selection criteria of scuba divers.

• 한국식생활문화학회지
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• 제22권2호
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• pp.274-282
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• 2007

This study was performed to make new products rising Pimpinella brachycarpa N., one of the Korean aromatic medicinal plant called chamnamul, which is a perennial plant of the Umbelliferae family. New products were natural chamnamul spice, chamnamul soup, chamnamul tea, and chamnamul mook as functional foods. The masking effect of Pimpinella brachvcarpa N., on fishy and meaty odor were investigated to test the usefulness of chamnamul as a natural spice. It could be concluded that the effect of added amounts of chamnamul on the cream soup increases the taste and appearance, and improves the flavor and color by the sensory evaluation. The chamnamul tea prepared by a filtration method is better than that by a leaching method on the preference test. In the texture properties of chamnamul mooks by a texture analyzer (XT-RA, Texturometer), the cohessiveness of them was higher than that of the white one.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2007년도 춘계학술대회 논문집
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• pp.156-159
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• 2007

Bathroom in apartment has the main functions of bath, washing hand and evacuation. The bathroom equipments for these functions are bathtub, shower booth, washbasin and toilet stool. Generally, these equipment are put together in one space, so it may cause people have trouble in using bathroom by other family members' occupation. Therefore the purpose of this study is to investigate the degree of preference about bathroom space fraction and grope for the connection with other spaces in apartment. The subject of this study were residents who live in brand apartments located in Seoul. The survey were carried out from november to December 2006. The data were analyzed through SPSS/PC+ using frequency, percentage and crossovers. The results of this study are as following, 1. A number of respondents would have trouble in using the bathroom by other family members' occupation once a week or more. The functional fraction of bathroom space is needed. 2. Close adjacency to Powder space, dress room is preferred. Coordination of washbasin and powder space is also needed. 3. Each separated spaces can be connected with other related spaces.

• Asian Pacific Journal of Cancer Prevention
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• 제15권23호
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• pp.10475-10481
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• 2015

Forkhead-box (FOX) transcription factors comprise a large gene family that contains more than 50 members in man. Extensive studies have revealed that they not only have functions in control of growth and development, but also play important roles in different diseases, especially in cancer. However, biological functions for most of the members in the FOX family remain unknown. In the present study, the expression of 39 FOX genes in 48 kinds of cancer was mined from the Gene Expression Atlas database of European Bioinformatics Institute. The analysis results showed that some FOX genes demonstrate overlapping expression in various cancers, which suggests particular biological functions. The pleiotropic features of the FOX genes make them excellent candidates in efforts aimed to give medical treatment for cancers at the genetic level. The results also indicated that different FOX genes may have the synergy or antagonistics effects in the same cancers. The study provides clues for further functional analysis of FOX genes, especially for the pleiotropic biological functions and crosstalk of FOX genes in human cancers.

• 한국도서관정보학회지
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• 제36권3호
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• pp.149-167
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• 2005

본 연구의 목적은 공공도서관 건축, 특히 공간구성에 대한 지역주민들의 다양한 의견을 조사하여 공공도서관을 신축하거나 리모델링할 때 활용할 수 있는 요인을 파악하는데 있다. 연구방법으로는 설문지법을 사용하였으며, 도서관 신축을 진행하고 있는 경기도 용인 지역의 주민을 대상으로 실시되었다. 조사결과 기능별 공간 비율과 공간배치에 관련된 요인들로 도서관 이용목적, 도서관 내 활동, 연령, 동반자 형태 등이 있었다. 도서관내 주요 활동은 독서가 가장 많은 부분을 차지하고 있었으며, 많은 주민들이 가족과 함께 도서관을 이용하는 성향을 보여주고 있어서 가족을 위한 공간이 필요하였다. 또한 연령별로 도서관내 활동의 차이가 있어 연령별로 적합한 공간의 확보가 요구되었다.

• 한국잠사곤충학회지
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• 제54권1_2호
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• pp.1-5
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• 2016

The dpp gene originated from the silkworms is an important gene that is well conserved in the genome of humans, cattle, rodents, poultry and Drosophila. The dpp gene belonging to the TGF-beta (Transforming Growth Factor-beta) superfamily is known to play an important role in several developmental stages. The $TGF-{\beta}$ gene family is a genetically well-conserved and playing an important role gene family in various species such as determining cell proliferation and differentiation, apoptosis and cell fate. In this review, we have confirmed the following studies data. The recent studies on the silkworm dpp gene have confirmed for the first time the biological functions such as promoting osteogenesis activity. In addition, previous data shows that dpp have developmental functions such as morphogenetic materials at the blastophyllum stage, induction of the mesoblast at the late embryonic stage and involved in the proliferation and morphogenesis of imaginal disc in adult development. We found the splice variant of the dpp gene originated from the wildtype silkworm by using comparative genomics. It has provided important data for basic research based on genetics studies of these processes may promote a better understanding of evolution. Silkworm is a medicinal insect and is approved for its safety. It is used as a natural antibiotic for promoting growth as a medical material, a health functional food, and a feed additive. Therefore, it is necessary to present various data to obtain more value of functional insect.

• Genomics & Informatics
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• 제12권4호
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• pp.240-246
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• 2014

Mutation in HNF1B, the hepatocyte nuclear factor-$1{\beta}$ (HNF-$1{\beta}$) gene, results in maturity-onset diabetes of the young (MODY) 5, which is characterized by gradual impairment of insulin secretion. However, the functional role of HNF-$1{\beta}$ in insulin secretion and glucose metabolism is not fully understood. We identified a family with early-onset diabetes that fulfilled the criteria of MODY. Sanger sequencing revealed that a heterozygous P159L (CCT to CTT in codon 159 in the DNA-binding domain) mutation in HNF1B was segregated according to the affected status. To investigate the functional consequences of this HNF1B mutation, we generated a P159L HNF1B construct. The wild-type and mutant HNF1B constructs were transfected into COS-7 cells in the presence of the promoter sequence of human glucose transporter type 2 (GLUT2). The luciferase reporter assay revealed that P159L HNF1B had decreased transcriptional activity compared to wild-type (p < 0.05). Electrophoretic mobility shift assay showed reduced DNA binding activity of P159L HNF1B. In the MIN6 pancreatic ${\beta}$-cell line, overexpression of the P159L mutant was significantly associated with decreased mRNA levels of GLUT2 compared to wild-type (p < 0.05). However, INS expression was not different between the wild-type and mutant HNF1B constructs. These findings suggests that the impaired insulin secretion in this family with the P159L HNF1B mutation may be related to altered GLUT2 expression in ${\beta}$-cells rather than decreased insulin gene expression. In conclusion, we have identified a Korean family with an HNF1B mutation and characterized its effect on the pathogenesis of diabetes.

• 정보관리연구
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• 제42권1호
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• pp.113-135
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• 2011

2010년 6월에는 IFLA에서 FRBR 시리즈의 세 번째 보고서인 '주제전거레코드의 기능상의 요건'(FRSAD)이 발표되었다. 이 개념모형은 최근의 주제전거 동향을 나타낼 뿐 아니라, FRBR 체제에 적합한 주제전거레코드를 위한 밑거름이 될 것이다. 이에 본 연구에서는 FRBR 시리즈의 맥락 안에서 FRSAD 모형을 분석하고, 이 모형을 우리나라의 주제명표와 서지레코드에 시범적으로 적용하였다. 이를 위해 개체와 속성, 관계를 중심으로 FRSAD 모형을 분석하였는데, 그 결과 FRSAD는 개체의 범주를 미리 규정하지 않은 개방성을 가지고 있으며, 테마와 노멘을 구분함으로써 주제명의 형식 측면 뿐아니라 개념 측면까지 강조하고 있음을 알 수 있었다. 그리고 이 개념모형을 FAST의 패싯과 연계하여 NLSH에 속한 일부 주제명의 개념구조와 주제전거와 관련된 서지레코드의 필드로 표현한 사례를 함께 제시하였다. 단, 본 연구에서는 인명과 단체명, 표제를 제외한 추가적인 개체로서의 주제전거 데이터만을 분석대상으로 하였다. 그 결과 FRSAD에서 별도로 정의하지 않은 제3집단 개체의 유형을 선정하는 기준과 그 기준을 주제명표에 일관되게 적용하는 방안이 필요함을 알 수 있었다. 앞으로는 보다 더욱 구체적인 적용 사례와 그 결과를 분석한 후속연구가 필요할 것이다.

• Biomolecules & Therapeutics
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• 제11권2호
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• pp.99-108
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• 2003

Background: There is abundance of studies on the decrease in body fat through limited calorie intake or exercise; however, studies focusing simultaneously on functional foods and exercise are rare. This study was aimed to identify the effects of combination of a functional beverage and exercise on body composition and biochemical metabolic profiles. Method: Eighty-one healthy volunteers (69 females aged 19 to 50 years and 12 males aged 19 to 55 years), who maintained their body weight stable with 23 or higher in BMI (kg/$m^2$) and 25% or higher body fat for the last three months, were recruited in the study through written advertisement. All the subjects gave their informed consent, and the study was conducted in accordance with the Declaration of Helsinki. The study design was a randomized double-blind placebo-controlled parallel group design. All participants were given 12-week programed-exercise, which was performed 3 times a week. One bottle (100 ml) of test (Garcinia cambogia 300 mg, L-carnitine 20 mg, Soy peptide 1,000 mg) or placebo solution was given daily 30 min before each session of programed-exercise. BMI (body mass index), %fat, local fat amount (visceral and mid-thigh), waist circumference, skin fold thickness and some biochemical metabolic parameters like glucose, insulin and free fatty acids, etc in the blood were measured and compared before and after 12-week intervention within groups as well as between groups according to the protocol Results: Twenty six volunteers were dropped out and fifty five volunteers completed the study. At the end of 4, 8, and 12 weeks, approximately 1.98%, 3.00% and 3.50% losses of initial body weight were observed, respectively, in the test group (P<0.01), and 0.29, % ,0.74%, 1.60%, respectively, in the placebo group (P>0.05). BMI changed by 2.40%, 3.41% and 4.46%, respectively, in the test group, and 0.38%, 0.95% and 1.75%, respectively, in the placebo group, at each period of time. The reductions of body weight and BMI were significantly higher in the test group than in the placebo group at each period of time (P<0.05). Conclusions: It is thought that the combination of functional beverage, which contains mostly garcinia cambogia, L-carnitine, and soy peptide, and exercise have synergy effects on reducing body fat.