• Title/Summary/Keyword: functional factor

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Novel CRF1-receptor Antagonists from Pulsatilla koreana Root

  • Li, Wei;Noh, Hyojin;Lee, Sunghou;Lee, Min Ho;Lee, Eun Young;Kang, Sangjin;Kim, Young Ho
    • Natural Product Sciences
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    • v.20 no.4
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    • pp.281-284
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    • 2014
  • In this study, twenty-one oleanane-type triterpenoid saponins were isolated from a methanol extract of the roots of Pulsatilla koreana. Antagonistic activities were measured in these compounds by the aequorin based cellular functional assay system for the corticotropin releasing factor receptor (CRF1). Of them, compounds 7 - 10 showed the highest degree of CRF1 inhibition further at the concentration of $10{\mu}M$. Moreover, by the analysis based on the structure-activity relationship of isolated saponins, a sugar chain at C-3 and a carboxyl group at C-28, as well as a methyl group at C-23 seems to be key functional elements. To our knowledge, this is the first report on CRF1 inhibition of saponins from P. koreana.

Effects of the Motivation for Rehabilitation on the Functional Performance of Stroke Patients

  • Kil, SoRa;Son, SungMin
    • The Journal of Korean Physical Therapy
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    • v.32 no.1
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    • pp.39-43
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    • 2020
  • Purpose: This study examined whether the motivation for rehabilitation influences the functional performance of stroke patients. Methods: To elucidate the same, correlation analysis between the 'rehabilitation motivation level' and 'functional performance improvement' was performed. Thirty-three stroke patients, who were hospitalized in rehabilitation and nursing hospitals, were enrolled in this study. Functional performance was assessed using the 10MWT, FRT, and the BBS. Statistical analysis was performed to determine the correlation between the reactivation symptoms and rehabilitation therapy at four weeks, eight weeks, and 12 weeks. Results: The results showed a significant correlation between the reactivation symptoms and rehabilitation therapy, as evidenced by the 10MWT, FRT, and BBS (8-12 weeks 10M gait test, Berg balance scale for 4-8 weeks, and 8-12 weeks). The FRT did not reveal any significant correlation between the rehabilitation program and reactivation. Conclusion: The present study confirmed that a higher motivation for rehabilitation in stroke patients resulting in a higher likelihood of it acting as a factor in improving their functional ability. Based on the above-mentioned results, this study suggests that a rehabilitation program could be considered for the motivation of patients to participate in a rehabilitation program.

Combined Effects of Physical Evidence and Functional Service at Bulgogi Restaurants on Customers' Store Image and Purchase Behaviors: Application of Video Scenario Technique

  • Hwang, Daye;Chang, Hyeja
    • Journal of the Korean Society of Food Culture
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    • v.35 no.2
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    • pp.181-192
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    • 2020
  • This study aimed to identify whether or not four service situations varying according to positive and negative combinations of physical evidence and functional service influence store image and purchase behavioral intentions of customers at bulgogi restaurants. The video-scenario technique was used for the study. Data were analyzed with the SPSS (Window 19.0) package using frequency analysis, one-way ANOVA, 2 by 2 factorial ANOVA, exploratory factor analysis, and multiple regression analysis to confirm the hypotheses. The combined effect of functional service and physical evidence influenced store image and purchase intention. In terms of seperate effect of physical evidence and functional service, the effect of employee service on store image was more powerful than that of physical evidence, even though the effect differed depending on the situation. Purchase intention was only influenced by functional service quality from employees under the four different scenarios. Thus, when opening a Korean restaurant, proper management of tangible evidence suitable to service, and the prices expected from local customers should be determined. Additionally, extremely high or low levels of physical evidence management should be avoided.

Effects of Acupuncture at GB30, GB34, and BL40 on Functional Recovery after Sciatic Crushed Nerve Injury in Rats

  • Lee, Moon-Kyu;Song, Yun-Kyung;Lim, Hyung-Ho
    • The Journal of Korean Medicine
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    • v.31 no.3
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    • pp.66-78
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    • 2010
  • Background: Peripheral nerve injuries are a commonly-encountered clinical problem and often result in a chronic pain and severe functional deficits. Objectives: The aim of this study was to evaluate the effects of acupuncture on the descending pain and the recovery of the locomotor function that follows sciatic crushed nerve injury in rats. Method: In order to assess the effects of acupuncture on the descending pain and functional recovery, we investigated the walking track analysis, brain-derived neurotrophic factor (BDNF) and its receptor tyrosine receptor kinase B (TrkB) expression in the sciatic nerve, and on the expressions of c-Fos and nitric oxide synthase in the paraventricular nucleus (PVN) of the hypothalamus and in the ventrolateral periaqueductal gray (vlPAG) region resulting from sciatic crushed nerve injury in rats. Results: Acupuncture treatment at Huantiao (GB30), Yanglingquan (GB34), and Weizhong (BL40) facilitated functional recovery. C-Fos and nitric oxide synthase expressions in the brain and BDNF and TrkB expressions in the sciatic nerve were decreased by acupuncture treatment. The most potent effects of acupuncture were observed at the GB30 acupoint. Conclusion: It is possible that acupuncture can be used for pain control and functional recovery from sciatic nerve injury.

Functional Forecasting of Seasonality (계절변동의 함수적 예측)

  • Lee, Geung-Hee
    • The Korean Journal of Applied Statistics
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    • v.28 no.5
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    • pp.885-893
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    • 2015
  • It is important to improve the forecasting accuracy of one-year-ahead seasonal factors in order to produce seasonally adjusted series of the following year. In this paper, seasonal factors of 8 monthly Korean economic time series are examined and forecast based on the functional principal component regression. One-year-ahead forecasts of seasonal factors from the functional principal component regression are compared with other forecasting methods based on mean absolute error (MAE) and mean absolute percentage error (MAPE). Forecasting seasonal factors via the functional principal component regression performs better than other comparable methods.

The Effect of a Family Restaurant's Brand Symbol on Brand Image, Preference, and Purchasing Intention (패밀리 레스토랑의 브랜드 심벌이 브랜드 이미지, 선호도 및 구매의도에 미치는 영향)

  • Kim, Ki-Yeong;Lee, Yong-Ho;Choi, Dong-Hee
    • Culinary science and hospitality research
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    • v.17 no.3
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    • pp.33-46
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    • 2011
  • This study is concerned with the effect of a brand symbol of a family restaurant on brand image, preference, and purchasing intention. With regard to analysis methods, the study carried out a reliability test and a validity test concerning a precedent research concept, ahead of verifying the hypothesis by using the SPSS Ver. 16.0. Also, the study conducted a frequency analysis, technical analysis, exploratory factor analysis, and regression analysis for verifying the hypothesis. As a result of the research, regarding a brand symbol as a visual symbol, three factors including a functional factor, a value factor, and an aesthetic factor were extracted, and of them, the functional factor and an aesthetic factor were discovered to influence of the brand image and preference which affected purchasing intention. In addition, consumers preferred a logo type that includes a company name or a brand name rather than a picture or a mark type of a symbol regarding a brand symbol, and they answered that outdoor advertising would raise awareness more than TV advertising. Based on these results, using a logo type symbol and the mix of outdoor advertising and TV advertising should be considered for brand launch.

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Structure and Properties of TLCP/Polyester Composite Fibers

  • Kim, Jun-Young;Kim, Seong-Hun
    • Proceedings of the Korean Fiber Society Conference
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    • 2003.10a
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    • pp.102-102
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    • 2003
  • TLCP/polyester composite fibers (TPCFs) based on melt blends of PEN, PET, and TLCP were prepared by melt blending and spinning process to achieve high performance fibers. Reinforcement effect and TLCP fibrillar structure resulted in improvement of mechanical properties for TPCFs. The increase in the apparent crystallite size was attributed to the development of larger crystallites and more ordered crystalline structures in the annealed TPCFs. Molecular orientation was an important factor to determine mechanical property of TPCFs.

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University Students' Awareness and Attitudes on Functional Clothing Materials (대학생의 기능성 의류 소재에 대한 인식과 태도에 관한 탐색적 연구)

  • Yoo, Hwa-Sook;Mun, Ji-Hyun;Choi, La-Yun;Jeon, Eun-Kyung;Han, Eung-Yeong
    • Korean Journal of Human Ecology
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    • v.18 no.1
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    • pp.145-155
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    • 2009
  • The purpose of this study is to examine the university students' awareness and attitudes on functional clothing materials, and to explore the effects of subjects' characteristics on the relationship between their attitudes to and images of the functional clothing materials. A total of 500 questionnaires were distributed to university students and 409 of which were used in data analysis. The data were statistically analyzed by frequency, factor analysis, reliability analysis, correlation analysis, t-test, ANOVA. The results were as follows: students thought that the first and foremost 'function' of functional clothing materials is their light-weight. The functions that consumers practically demanded are water-repellency and high absorbency & quick drying. It showed that students have an image that functional clothing materials have special, good and satisfactory qualities. Goretex and Coolmax were the most selected as brands of functional clothing materials which students knew. Attitudes to functional clothing materials revealed positively in the cognitive, behavioral and affectional attitudes. The attitudes had no significant differences according to sex and their major, but they had significant differences by subjects' amount of allowance, frequency of sports participation and sports ability. In other words, the more amount of allowance they get, the more frequently students do exercise, and the higher sports ability they have, the more positive attitude they have. The study says, in conclusion, that their conception of functional clothing materials has positive relations with their attitudes toward them.