• Title/Summary/Keyword: functional compound

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A Feature-based Approach to Compound Surface Design (특징형상을 이용한 복합곡면의 설계)

  • Jeong, Jaehun;Kim, Kwangsoo
    • Journal of the Korean Society for Precision Engineering
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    • v.12 no.2
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    • pp.112-122
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    • 1995
  • While many surfaces such as automobile outer panels, ship hulls and airfoils are characterized by their smooth, free-form shapes, a far larger class of functional surfaces are characterized by highly irregular, multi-featured shapes consisting of pockets, channels, ribs, etc. In constaract to the design of aesthetic, free-form surfaces, functional surface design can perhaps best be viewed as a process of assembling a collection of known component surfaces to form a single compound surface. In this paper, we presents a feature-based functional surface modeling method. A single feature involves a secondary surface, which we must join to a primary surface with a smooth transition between two boundary courves. Through recursive blending of a secondary surface with the primary surface, the mullti-featured surface is represented. After constructing a compound surface, we generate the Z-map for NC machining of the surface. Offsetting the Z-map using the inverse offsetting technique, we get CL tool paths with out gouging.

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Functional Properties of Cholesterol-removed Compound Whipping Cream by Palm Oil

  • Shim, S.Y.;Ahn, J.;Kwak, H.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.6
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    • pp.857-862
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    • 2004
  • The present study was carried out to examine the changes in functional properties of cholesterol-removed compound whipping cream made by $\beta$-CD treated cream and palm oil. Six different ratios of cream to palm oil (10:0 as control, 9:1, 8:2, 7:3, 6:4, and 5:5, v/v) were tested. The overrun percentage increased with an increased amount of palm oil. When the ratio of cream to palm oil was 10:0 (control), the overrun was 130%, which was significantly lower than other ratios reached to 150%. Foam instability was measured as 3.1 ml defoamed cream in control, however, the value of foam instability decreased with an increase of palm oil addition. The TBA value of cholesterol-removed compound whipping cream increased from 0.08 to 0.13 with no addition of palm oil during 4 wk storage. When the ratio of cream to palm oil was 5:5, TBA value increased dramatically at 3 wk and thereafter. Among sensory characteristics, texture value increased with higher amount of palm oil, however, flavor and overall preferences were opposite. Above results indicated that partial substitution of palm oil in manufacture of cholesterol-removed compound whipping cream resulted in a stable foam development with little adverse effect on flavor and lipid oxidation during storage. The present study showed a possible application in manufacture of cholesterol-removed compound whipping cream, which may be effective in other foods.

Study on Inhibition of Platelet Aggregation of Bioactive Constituents from Paeonia lactiflora (작약의 혈소판 응집억제작용에 관한 연구)

  • 박관혁;서범석;손동주;박영현;장성근
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.4 no.4
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    • pp.357-360
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    • 2003
  • Methanol extracts from Paeonia lactiflora showed a strong inhibition against platelet aggregation on platelet activation test. Therefore, the bioactive constituents from Paeonia lactiflora were prepared using chromatography methods and were analyzed by NMR and reference data. Compound 1b was confirmed a same structure with henzoyloxypaeoniflorin, compound 2e was a same structure with paeoniflorin; main product of Paeonia lactiflora. Analytical data of compound 3a were not consistent with any known paeoniflorin soucture, but showed the souctural similarity with it. And also the aggregation inhibition activity of compound 3a showed a strong inhibition($\geq$ 90%) induced by collagen. Therefore it suggested that the structure of compound 3a may be the similar structure of benzoyloxypaeoflorin with a functional group in place of benzoyl group and/or a different functional group in stead of Rl. We suggested that benzoyl group of benzoyloxypaeoniflorin substitued instead of 5-carbon OH group on glycoside moiety paeoniflorin played role of the metabolite in case of a platelet aggregation inhibition activity. Paeoniflorin showed more strong inhibition by thrombin than collagen. Therefore, it may be destructed a calcium metabolite as a forming $Ca^2+$ chelate. Compound 3a may be that other functional group instead of OH group of 5-carbon on glycoside moiety of paeoniflorin and/or OH group of benzoyl moiety of paeoniflorin played role of the metabolite in a platelet aggregation inhibition.

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3-Phenethyl-2-phenylquinazolin-4(3H)-one isolated from marine-derived Acremonium sp. CNQ-049 as a dual- functional inhibitor of monoamine oxidases-B and butyrylcholinesterase

  • Jong Min Oh;Prima F. Hillman;Sang-Jip Nam;Hoon Kim
    • Journal of Applied Biological Chemistry
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    • v.66
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    • pp.165-170
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    • 2023
  • Isolation of the culture broth of a marine-derived Acremonium sp. CNQ-049 guided by HPLC-UV yielded compound 1 (3-phenethyl-2-phenylquinazolin-4(3H)-one), and its inhibitory activities against monoamine oxidases (MAOs), cholinesterases (ChEs), and β-secretase 1 (BACE1) were evaluated. Compound 1 was an effective selective MAO-B inhibitor with an IC50 value of 9.39 µM and a selectivity index (SI) value of 4.26 versus MAO-A. In addition, compound 1 showed a potent selective butyrylcholinesterase (BChE) inhibition with an IC50 value of 7.99 µM and an SI value of 5.01 versus acetylcholinesterase (AChE). However, compound 1 showed weak inhibitions against MAO-A, AChE, and BACE1. The Ki value of compound 1 for MAO-B was 5.22±1.73 µM with competitive inhibition, and the Ki value of compound 1 for BChE was 3.00±1.81 µM with mixed-type inhibition. Inhibitions of MAO-B and BChE by compound 1 were recovered by dialysis experiments. These results suggest that compound 1 is a dual-functional reversible inhibitor of MAO-B and BChE, that can be used as a treatment agent for neurological disorders.

A Comparison Study on Reinforcement Behaviors of Functional Fillers in Nitrile Rubber Composites

  • Seong, Yoonjae;Lee, Harim;Kim, Seonhong;Yun, Chang Hyun;Park, Changsin;Nah, Changwoon;Lee, Gi-Bbeum
    • Elastomers and Composites
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    • v.55 no.4
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    • pp.306-313
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    • 2020
  • To investigate the reinforcing effects of functional fillers in nitrile rubber (NBR) materials, high-structure carbon black (HS45), coated calcium carbonate (C-CaCO3), silica (200MP), and multi-walled carbon nanotubes (MWCNTs) were used as functional filler, and carbon black (SRF) as a common filler were used for oil-resistant rubber. The curing and mechanical properties of HS45-, 200MP-, and MWCNT-filled NBR compounds were improved compared to those of the SRF-filled NBR compound. The reinforcing effect also increased with a decrease in the particle size of the fillers. The C-CaCO3-filled NBR compound exhibited no reinforcing effect with increasing filler concentration because of their large primary particle size (2 ㎛). The reinforcing behavior based on 100% modulus of the functional filler based NBR compounds was compared by using several predictive equation models. The reinforcing behavior of the C-CaCO3-filled NBR compound was in accordance with the Smallwood-Einstein equation whereas the 200MP- and MWCNT-filled NBR compounds fitted well with the modified Guth-Gold (m-Guth-Gold) equation. The SRF- and HS45-filled NBR compounds exhibited reinforcing behavior in accordance with the Guth-Gold and m-Guth-Gold equations, respectively, at a low filler content. However, the values of reinforcement parameter (100Mf/100Mu) of the SRF- and HS45-filled NBR compounds were higher than those determined by the predictive equation model at a high filler content. Because the chains of SRF composed of spherical filler particles are similarly changed to rod-like filler particles embedded in a rubber matrix and the reinforcement parameter rapidly increased with a high content of HS45, the higher-structured filler. The reinforcing effectiveness of the functional fillers was numerically evaluated on the basis of the effectiveness index (��SRF/��f) determined by the ratio of the volume fraction of the functional filler (��f) to that of the SRF filler (��SRF) at three unit of reinforcing parameter (100Mf/100Mu). On the basis of their effectiveness index, MWCNT-, 200MP-, and HS45-filled compounds showed higher reinforcing effectiveness of 420%, 70%, and 20% than that of SRF-filled compound, respectively whereas C-CaCO3-filled compound exhibited lower reinforcing effectiveness of -50% than that of SRF-filled compound.

Optimization of Conditions for High Concentration of Eleutheroside E and Chlorgenic Acid Components of Acanthopanax koreanum Stem Extract

  • Kim, Sung Gi;Yang, Byung Wook;Lee, Jae Bum;Kim, Sa Hyun;Ko, Sung Kwon
    • Biomedical Science Letters
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    • v.26 no.4
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    • pp.319-326
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    • 2020
  • This study was conducted to develop a new functional material by optimizing the conditions for high concentrations of chlorogenic acid and eleutheroside E in Acanthopanax koreanum stem. The total phenolic compound content was the highest in the 20 hours sonication Acanthopanax koreanum stem extract (UAK-20). In addition, eleutheroside E, a typical functional ingredient of Cortex Acanthopanacis, in the 20 hours treated Acanthopanax koreanum stem extract showed the highest content at 1.646%. However, another functional ingredient, chlorogenic acid, showed the highest content of 2.625% in 1 hour treated Acanthopanax koreanum stem extract. Therefore, it is considered that the optimal conditions for high concentrations of total phenolic compound and eleutheroside E are 20 hours sonication Acanthopanax koreanum stem extract.

Effect of Reduction of Phytate and Phenol Compound on the Functional Properties of Sesame Protein Concetrate (참깨박에 함유된 Phytate와 Phenol 화합물의 제거가 단백질의 기능성에 미치는 영향)

  • Kim, Jin;Park, Jyung-Rewng
    • Journal of the East Asian Society of Dietary Life
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    • v.3 no.2
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    • pp.129-137
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    • 1993
  • This study was attempted to determine the effect of reduction of phytate and phenol compound on the functional properties of sesame protein concentrate. The concentrates were prepared by using dist-water, HCI and butanol. The content of phytate and phenol compound in defatted sesame meal were 4.55% and 3.42% respectively. Considerable amount of phytate was reduced by using HCI, and butanol was effective in removing phenol compounds, Higher bulk density and fat absorption were found in sesame protein concentrate prepared by butanol but higher water absorption was found in the concentrate prepared by dist-water. Also, emulsifying and foaming properties were improved by butanol treatment.

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A Conformational Comparison of 1,2-Bis(phenylthio)-o-carborane, $C_{14}H_{20}B_{10}S_2$, by X-Ray Diffraction Method and Molecular Orbital Calculation

  • Song, Kyu-Ho;Ko, Jae-Jung;Kang, Sang-Ook;Han, Won-Sik;Kwon, Soon-Nam;Suh, Il-Hwan
    • Korean Journal of Crystallography
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    • v.19 no.1
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    • pp.1-6
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    • 2008
  • The reaction of dilithio-o-carborane with dipenyl disulfide produces a phenyl thiolated o-carborane and it has been confirmed that there is conformational similarity between the structure of the compound elucidated by X-ray crystallography and that calculated by ab initio and density functional theory.

Development of Susceptible Functional Fibers Using Microencapsulation of Susceptible Materials(III) ―Fragrant Functional Fibers― (감성물질의 마이크로캡슐화에 의한 감성기능 섬유의 개발(III) -방향 기능 섬유-)

  • Kim, Moon Sik;Park, Soo Min
    • Textile Coloration and Finishing
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    • v.8 no.4
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    • pp.11-18
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    • 1996
  • Natural functional compound in the textile finishing for health and amenity using fragrant material have been applied by microencapsulation method. The microcapsules containing fragrant materials as functional compound were produced by in situ polymerization using urea-formaldehyde prepolymer. The average diameter of microcapsules is 2.75$\mu$ and particle size ranges over 0.5~10$\mu$. Fragment material is extracted approximatly proportioned from microcapsule at room temperature. The adsorption of microcapsule was improved by pretreatment of cationic agent. Fragrant materials in microcapsule was revealed to have long release time.

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