• KSCE Journal of Civil and Environmental Engineering Research
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• v.10 no.2
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• pp.67-78
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• 1990

An inverse self-iterative procedure is developed to determine layer moduli which are significant for the structural evaluation of pavements in developing rational and analytical rehabilitation technique. Falling weight deflectometer(FWD) is adopted as a non-destructive testing(NDT)device. The layer elastic theory is used to interpret NDT data. The theoretical deflection basins of pavement structures obtained by full factorial design are used for a parametric study on the characteristics of deflection basins and regression analyses. Regression equations to estimate layer moduli of flexible pavements are proposed through the regression analyses of theoretical deflection basins. The relationships between the rate of change of moduli and deflections are developed for the efficient iteration. An inverse self-iterative procedure to ensure the accuracy of the layer moduli is proposed. Validity and applicability of the developed procedure are verified through various numerical model tests.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.7
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• pp.1032-1038
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• 2003

The two-level full factorial and mixture design were used to screen ingredient type and to investigate the effects of ingredients on properties of surimi gel from jack mackerel using measurements of breaking forces, deformation values and color. The addition of starch decreased breaking force significantly (p<0.05), but did not affect deformation. The bovine plasma protein (BPP) among non-muscle proteins increased a breaking force and deformation value. However, the dried egg white increased slightly a breaking force, and decreased greatly a deformation value. The breaking force of gel was increased, but deformation value did not change significantly (p<0.05) with adding BPP. The whiteness of gel was slightly improved with the addition of corn starch and BPP. At 78% moisture, the optimum ratios of ingredients were 89.5∼90.0% for alkali surimi, 4.6∼6.0% for corn starch and 4.3∼5.4% for BPP to obtain above 110g for a breaking force, 4.2 mm for a deformation, and 22.5 for a whiteness.

• Journal of Microbiology and Biotechnology
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• v.22 no.2
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• pp.199-206
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• 2012

Naturally immobilized tannase (tannin acyl hydrolase, E.C. 3.1.1.20) has many advantages, as it avoids the expensive and laborious operation of isolation, purification, and immobilization, plus it is highly stable in adverse pH and temperature. However, in the case of cell-associated enzymes, since the enzyme is associated with the biomass, separation of the pure biomass is necessary. However, tannic acid, a known inducer of tannase, forms insoluble complexes with media proteins, making it difficult to separate pure biomass. Therefore, this study optimizes the production of cell-associated tannase using a "protein-tannin complex" free media. An exploratory study was first conducted in shake-flasks to select the inducer, carbon source, and nitrogen sources. As a result it was found that gallic acid induces tannase synthesis, a tryptose broth gives higher biomass, and lactose supplementation is beneficial. The medium was then optimized using response surface methodology based on the full factorial central composite design in a 3 l bioreactor. A $2^3$ factorial design augmented by 7 axial points (${\alpha}$ = 1.682) and 2 replicates at the center point was implemented in 17 experiments. A mathematical model was also developed to show the effect of each medium component and their interactions on the production of cell-associated tannase. The validity of the proposed model was verified, and the optimized medium was shown to produce maximum cell-associated tannase activity of 9.65 U/l, which is 93.8% higher than the activity in the basal medium, after 12 h at pH 5.0, $30^{\circ}C$. The optimum medium consists of 38 g/l lactose, 50 g/l tryptose, and 2.8 g/l gallic acid.

• Journal of Life Science
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• v.7 no.4
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• pp.342-346
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• 1997

This experiment was carried out to clarify the effects of gibberellin(GA) aplication and bagging on repeening and quality in 'Delaware' grape berries. Treatments are 4 plots(2X2 factorial experiment); GA, GA+bagging, bagging and control. The clusters were dipped twice in 100 ppm GA with GA treatment : 10 days before and after the full bloom. The results obtained as follows: 1. GA treatment made the seedless grape berry reduced in the fresh weight but it hastened the ripening period about 2 weeks. 2. Total soluble solid(TSS), viscosity and pH value of berry juice increased with maturation. The concentration of TSS and viscosity were higher in GA treatment plot than GA non-treatment. 3. Berry-hardness, titratable acidity and alcohol inslouble solid(AIS) decreased with maturation. Expically berry-hardness and AIS decreased more greatly in GA non-treatment than GA treatment. 4. The concentration of anthocyanin increased with ripening but pectic substance didn't fluctuate nearly. These of anthocyanin and pectin were higher in GA non-treatment plot than GA treatment. 5. By analysis of factorial experiment GA treatment was highly significant with the $^{o}$Brix/Acidity ratio, juice viscosity and AIS, but high negatively, significant with berry-hardness and berry fresh weight. And it was significant with T S S and negatively, titratable acidity. Bagging was significant with $^{o}$Brix/Acidity ratio and AIS content, but negatively, titratable acidity. 6. Qualitative characters were high correlated with the $^{o}$Brix/Acidity ratio in simple correlation but direct effect by the path-coefficient analysis didn't coincide with simple correlation. The direct effect of pH was large and juice viscosity, the next. And that of berry-hardness was negligible but, AIS, small negatively.

• Horticultural Science & Technology
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• v.31 no.1
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• pp.38-49
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• 2013

Prohexadione-calcium (Pro-Ca), ethephon and transient water stress were evaluated in a factorial design, as potential inhibitors of early-season shoot growth of high density orchard management of apple (Malus domestica Borkh.) trees. In the experiment, water stress was imposed to one-half of the 7-year-old 'Golden Delicious'/M.9 apple trees in each of 5 blocks, by stopping irrigation for 3 weeks between 35 and 56 days after full bloom (AFB). Within each whole unit, the following Pro-Ca and ethephon treatments were randomly allocated at $2{\times}2$ factorial: a) 0 or 250 $mg{\cdot}L^{-1}$ a.i. Pro-Ca applied at 28 days AFB and b) 0 or 300 $mg{\cdot}L^{-1}$ a.i. ethephon applied twice (35 and 71 days AFB). All trees were hand thinned to king flowers prior to treatments. Vegetative shoot growth was markedly reduced by Pro-Ca, with its effect being obvious within 14 days after application, while ethephon and water stress treatments were less effective. Pro-Ca had no effect on fruit set and yield but slightly increased fruit size. Ethephon substantially reduced the fruit size and yield but had no effect on fruit set. Water stress reduced fruit set, fruit size and yield. With regard to fruit quality, Pro-Ca did not influence fruit shape, flesh firmness and soluble solids contents (SSC) but slightly reduced titratable acidity. Ethephon had no effect on fruit shape but increased firmness, SSC and acidity, while water stress did not influence these fruit quality attributes. Dry weight of dormant spur buds was reduced by both Pro-Ca and water stress, while increased by ethephon. The larger dormant buds led to the larger spur flowers at the tight cluster stage the following spring. Return flowering was promoted only by ethephon, especially on previous season's shoots. There were no significant interactions between Pro-Ca and ethephon or water stress on most variables observed in this study.

• Journal of the Korean Applied Science and Technology
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• v.37 no.6
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• pp.1738-1751
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• 2020

The skin is divided into three parts: the epidermis, the dermis, and the subcutaneous fat, and the stratum corneum, which is located at the top of the epidermis, acts as a barrier that prevents drug delivery. Nanoemulsions are known to be effective in transdermal delivery of drugs through intercellular lipids because of their unique small particle size. In this study, phase inversion temperature (PIT) nanoemulsion containing α-bisabolol was optimized using response surface methodology (RSM) for effective skin absorption of α-bisabolol. As a preliminary experiment, the 25-2 fractional factorial design method and the 23 full factorial design method were performed. Box-Behnken design was performed based on the results of the factorial design method. The content of surfactant (6.3~12.6%), co-surfactant (5.2~7.8%) and α-bisabolol (0.5~5.0%) were used as factors, and the dependent variable was the particle size of the nanoemulsion. PIT nanoemulsion optimization was performed according to the RSM results, and as a result, the optimal nanoemulsion formulation conditions were predicted to be 10.4% surfactant content, 6.3% co-surfactant content, and 5.0% α-bisabolol content. As a result of the skin absorption test, the final skin absorption rate of the PIT nanoemulsion was 35.11±1.01%, and the final skin absorption rate of the general emulsion as a control was 28.25±1.69%, confirming that the skin absorption rate of the PIT nanoemulsion was better.

• Applied Chemistry for Engineering
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• v.20 no.2
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• pp.234-240
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• 2009

$Mg(OH)_2$ particles were prepared by precipitation and a hydrothermal treatment to examine the effect of $MgCl_2$ concentration, alkali type and concentration, temperature, hydrothermal treatment on the formation of $Mg(OH)_2$ particles using full factorial design, as one of DOE (Design of experiment) methods. The primary particle size is similar to the secondary particle size for the samples after the hydrothermal treatment, where the average particle size of $Mg(OH)_2$ increased with increasing the concentration of $MgCl_2$ and hydrothermal temperature and decreasing alkali/Mg molar ratio. On the other hand, for the samples prepared from precipitation, the secondary particle size is larger than the primary particles due to aggregation. The difference in alkaline source is that the particles prepared from $NH_4OH$ exhibit the larger size with better dispersion than those from NaOH. Low density polyethylene and ethylene-co-vinyl acetate (LDPE-EVA) resin composed of the smaller secondary particle size of $Mg(OH)_2$ shows a higher limited oxygen index (LOI) at 50 and 55% loading, but the smaller primary particle size may result in a better grade in UL-94 tests. At the high loading of 60%, all samples with any preparation methods exhibit V-0 grade but the LOI value depends on not only primary particle size but also dispersion state.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1845-1848
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• 2005

The automatic $CO_2$ welding is a manufacturing process to produce high quality joints for metal and it could provide a capability of full automation to enhance productivity. Despite the widespread use in the various manufacturing industries, the full automation of the robotic $CO_2$ welding has not yet been achieved partly because the mathematical model for the process parameters of a given welding task is not fully understood and quantified. Several mathematical models to control welding quality, productivity, microstructure and weld properties in arc welding processes have been studied. However, it is not an easy task to apply them to the various practical situations because the relationship between the process parameters and the bead geometry is non-linear and also they are usually dependent on the specific experimental results. Practically, it is difficult, but important to know how to establish a mathematical model that can predict the result of the actual welding process and how to select the optimum welding condition under a certain constraint. In this research, an attempt has been made to develop an intelligent algorithm to predict the weld geometry (top-bead width, top-bead height, back-bead width and back-bead height) as a function of key process parameters in the robotic $CO_2$welding. A sensitivity analysis has been conducted and compared the relative impact of three process parameters on bead geometry in order to verify the measurement errors on the values of the uncertainty in estimated parameters.

• Korean Journal of Weed Science
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• v.32 no.1
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• pp.17-24
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• 2012

The study was conducted to investigate the effect of weed interference and starter fertilizer on subsequent soybean seed quality at the Agricultural Research Farm and Laboratory of Razi University, Kermanshah, Iran. Two factorial experiment was laid-outon a randomized complete block design with four replications. First factor was starter fertilizer levels (0 and 25 kg $ha^{-1}$) applied in the forms of monoammonium phosphate, the second factor was different weed interference periods consisted of five initial weed-free periods (in which, plots were kept free of weeds for 0, 15, 30, 45 and 60 days after crop emergence (DAE) and then weeds were allowed to grow until harvest) and five initial weed-infested periods (in which, weeds were allowed to grow for 0, 15, 30, 45 and 60DAE, after which the plots were kept free of weeds until harvest). Full season weedy condition reduced 100-seed weight, seed germination percentage and seedling dry weight by 25.9, 13.3 and 22.5%, respectively and increased mean germination time and seed electrical conductivity by 55.8 and 24.3%, respectively as compared with full season weed-free control. However, the traits under study were not significantly influenced when field was kept free of weeds for at least 45 DAE (R1) or weedy condition was continued for less than 30 DAE (V8). There was a significant and negative correlation between weed biomass and seed weight (r = -0.93), so that when weed free condition was less than 45 DAE or weed infested period was continued for at least 30 DAE, soybean plants produced wrinkled and underdeveloped seeds with lower weights and qualities. Moreover, soybean seed quality reduction due to weed interference was more evident when starter fertilizer was applied and weeds interfered with soybean from the beginning of the growing season. Information from the present study is beneficial in soybean seed production systems and where farmers use the harvested seeds for the following planting.

• Computers and Concrete
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• v.17 no.3
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• pp.323-336
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• 2016

Although the self-compacting concrete (SCC) offers several practical and economic benefits and quality improvement in concrete constructions, in comparison with conventionally vibrated concretes confronts with autogenously chemical and drying shrinkage which causes the formation of different cracks and creates different problems in concrete structures. Using different fibers in the mix design and implementation of fibrous concrete, the problem can be solved by connecting cracks and micro cracks together and postponing the propagation of them. In this study an experimental investigation using response surface methodology (RSM) based on full factorial design has been undertaken in order to model and evaluate the polypropylene fiber effect on the fibrous self-compacting concrete and curing time, fiber percentage and fiber amount have been considered as input variables. Compressive strength has been measured and calculated as the output response to achieve a mathematical relationship between input variables. To evaluate the proposed model analysis of variance at a confidence level of 95% has been applied and finally optimum compressive strength predicted. After analyzing the data, it was found that the presented mathematical model is in very good agreement with experimental results. The overall results of the experiments confirm the validity of the proposed model and this model can be used to predict the compressive strength of fibrous self-compacting concrete.