• 한국융합학회논문지
• /
• 제10권10호
• /
• pp.117-122
• /
• 2019

슬로싱 현상은 현상의 특성인 격렬한 자유표면을 가지는 유동 문제뿐만 아니라, 슬로싱이 발생하는 유체 탱크가 부유체 혹은 어떠한 물체에 탑재되어 전체 시스템에 영향을 줄 수 있다는 것이 가장 큰 논의점이다. 이러한 이유로 일반적인 슬로싱에 대한 해석은 탱크의 움직임에 의한 내부 유동의 발생, 그리고 그로 인해 야기되는 충격하중의 해석이 주를 이룬다. 이러한 슬로싱 현상은 비선형성이 강하며 자유표면에서의 대-변형이 발생한다. 매우 높은 비선형성으로 인해 실험에서는 재현성이 낮고, 수치 시뮬레이션에서는 정확도가 낮다는 것이 지속적으로 문제시 되어 왔다. 본 연구에서는 높은 정확도를 가지는 카메라 비전 기술을 이용한 실험과 입자법을 이용한 시뮬레이션을 비교하였다. 탱크의 주요 제원을 통해 구해진 고유 주기와 그 주변 주기를 가지는 운동에서의 슬로싱 현상을 수치적으로 시뮬레이션 하였으며, 비교를 통해 탱크 내 슬로싱 하중을 분석하였다.

• 한국가스학회지
• /
• 제23권1호
• /
• pp.1-11
• /
• 2019

한국 정부는 액화 천연가스를 대체하는 에너지원으로서 러시아의 파이프라인 천연가스 도입을 1990년대 이후부터 지속적으로 모색해오고 있다. 이러한 동북아 에너지 협력에 대한 논의가 현실 정치뿐만 아니라 학술적인 차원에서도 다양하게 진행되고 있지만, 기존의 선행연구들은 협력의 당위성만을 제시하고 있을 뿐이지 이론적 분석틀이 미약하다는 한계를 지니고 있다. 이에 본 논문에서는 경제통합론이라는 이론적 자원을 바탕으로 에너지협력의 동기 조건 단계를 분석하고자 한다. 연구 결과 동북아 천연가스 협력과 관련해서는 경제적 동기만이 유일하기는 하지만, 실질적인 기대이익뿐만 아니라 경제구조의 보완성과 정책목표의 수렴성이라는 조건들이 갖추어진 것으로 파악되었다. 결론적으로 동북아에서 높은 수준의 에너지 협력은 어렵겠지만 특혜무역협정 수준의 초보적인 천연가스 협력이 가능하다는 전망이 제시될 수 있었다.

• 대한의용생체공학회:의공학회지
• /
• 제42권3호
• /
• pp.125-142
• /
• 2021

The POCT (point-of-care test) sensing that has been a fast-developing field is expected to be a next generation technology in health care. The POCT sensors for the detection of proteins, small molecules and especially nucleic acids have lately attracted considerable attention. According to the World Health Organization (WHO), the POCT methods are required to follow the ASSURED guidelines (Affordable, Sensitive, Specific, User- friendly, Robust and rapid, Equipment-free, Deliverable to all people who need the test). Recently, several CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) based diagnostic techniques using the sensitive gene recognition function of CRISPR have been reported. CRISPR/Cas (Cas, CRISPR associated protein) systems based detection technology is the most innovative gene analysis technology that is following the ASSURED guidelines. It is being re-emerged as a powerful diagnostic tool that can detect nucleic acids due to its characteristics that enable rapid, sensitive and specific analyses of nucleic acid. The first CRISPR-based diagnosis begins with the discovery of the additional function of Cas13a. The enzymatic cleavage occurs when the conjugate of Cas protein and CRISPR RNA (crRNA) detect a specific complementary sequence of the target sequence. Enzymatic cleavage occurs on not only the target sequence, but also all surrounding non-target single-stranded RNAs. This discovery was immediately utilized as a biosensor, and numerous sensor studies using CRISPR have been reported since then. In this review, the concept of CRISPR, the characteristics of the Cas protein required for CRISPR diagnosis, the current research trends of CRISPR diagnostic technology, and some aspects to be improved in the future are covered.

• Journal of Chest Surgery
• /
• 제55권2호
• /
• pp.101-107
• /
• 2022

Background: Spread through air spaces (STAS) has recently emerged as a prognostic factor in lung adenocarcinoma, but little is known about the association of STAS and its grade with recurrence in neuroendocrine tumors (NETs). This study investigated the prognostic effect of STAS grade in NETs after curative resection. Methods: Seventy-seven patients were retrospectively reviewed, including 9 with typical carcinoid (TC), 6 with atypical carcinoid (AC), 26 with large cell neuroendocrine carcinoma (LCNEC), and 36 with small cell carcinoma (SCC). STAS was defined as the presence of floating tumor cells within air spaces in the lung parenchyma beyond the edge of the main tumor. STAS was classified as grade 1 or 2 depending on whether it was found within or beyond one ×10 objective lens field away from the main tumor margin, respectively. Results: Fifty-four patients (70%) had STAS, including 22% with TC, 50% with AC, 69% with LCNEC, and 86% with SCC. Patients with STAS had more nodal metastasis, lymphatic and vascular invasion, tumor necrosis, and tumor subtypes other than TC. Among STAS cases, grade 2 STAS was present in 33% of AC, 78% of LCNEC, and 87% of SCC. The 5-year recurrence-free survival (RFS) rate was 81%, 63%, and 35% in patients with no STAS, grade 1, and grade 2 STAS, respectively. Multivariate analysis found that grade 2 STAS was an independent negative prognostic factor for RFS. Conclusion: Although STAS itself was not associated with a poor prognosis, grade 2 STAS was an independent negative prognostic factor for RFS.

• Wind and Structures
• /
• 제34권2호
• /
• pp.199-213
• /
• 2022

The current study investigates the dynamic effects in the tornado-structure response of an aeroelastic self-supported lattice transmission tower model tested under laboratory simulated tornado-like vortices. The aeroelastic model is designed for a geometric scale of 1:65 and tested under scaled down tornadoes in the Wind Engineering, Energy and Environment (WindEEE) Research Institute. The simulated tornadoes have a similar length scale of 1:65 compared to the full-scale. An extensive experimental parametric study is conducted by offsetting the stationary tornado center with respect to the aeroelastic model. Such aeroelastic testing of a transmission tower under laboratory tornadoes is not reported in the literature. A multiaxial load cell is mounted underneath the base plate to measure the base shear forces and overturning moments applied to the model in three perpendicular directions. A three-axis accelerometer is mounted at the level of the second cross-arm to measure response accelerations to evaluate the natural frequencies through a free-vibration test. Radial, tangential, and axial velocity components of the tornado wind field are measured using cobra probes. Sensitivity analyses are conducted to assess the variation of the structural dynamic response associated with the location of the tornado relative to the lattice transmission tower. Three different layouts representing the change in the orientation of the tower model relative to the components of the tornado-induced loads are considered. The structural responses of the aeroelastic model in terms of base shear forces, overturning moments, and lateral accelerations are measured. The results are utilized to understand the dynamic response of self-supported transmission towers to the tornado-induced loads.

• Steel and Composite Structures
• /
• 제41권5호
• /
• pp.761-773
• /
• 2021

This study presents a 3D non-linear finite element (FE) assessment of dynamic soil-structure interaction (SSI). The numerical investigation has been performed on the time domain through a Finite Element (FE) system, while considering the nonlinear behavior of soil and the multi-directional nature of genuine seismic events. Later, the FE outcomes are analyzed to the recorded in-situ free-field and structural movements, emphasizing the numerical model's great result in duplicating the observed response. In this work, the soil response is simulated using an isotropic hardening elastic-plastic hysteretic model utilizing HSsmall. It is feasible to define the non-linear cycle response from small to large strain amplitudes through this model as well as for the shift in beginning stiffness with depth that happens during cyclic loading. One of the most difficult and unexpected tasks in resolving soil-structure interaction concerns is picking an appropriate ground motion predicted across an earthquake or assessing the geometrical abnormalities in the soil waves. Furthermore, an artificial neural network (ANN) has been utilized to properly forecast the non-linear behavior of soil and its multi-directional character, which demonstrated the accuracy of the ANN based on the RMSE and R² values. The total result of this research demonstrates that complicated dynamic soil-structure interaction processes may be addressed directly by passing the significant simplifications of well-established substructure techniques.

• Journal of Korea Trade
• /
• 제27권3호
• /
• pp.199-216
• /
• 2023

Purpose - This study aims to identify the internal capabilities that export companies need to possess in order to utilize FTAs and to propose ways to expand their export performance through them. To achieve this goal, the study analyzed the internal factors that affect FTA utilization from a resource-based perspective, such as Origin Management Competency, Information Acquisition Competency, contract Management Competency, and Commitment to Export, based on prior research on corporate capabilities in the field of management and FTA-related research. The study ultimately aims to confirm whether a company's FTA utilization contributes to its export performance through the management and response to its internal factors for FTA utilization. Design/methodology - To achieve the research objective, this study conducted a literature review related to FTA utilization and identified the internal factors of companies that affect FTA by classifying them into Origin Management Competency, Information Acquisition Competency, contract Management Competency, and Commitment to Export Based on this, a final research model was developed, hypotheses were set through a preliminary study survey, and conclusions were drawn by analyzing the data of 312 companies. Findings - The empirical analysis results indicate that Origin Management Competency and Contract Management Competency have a positive impact on FTA utilization, while Information Acquisition Competency and Commitment to Export do not have a statistically significant impact on FTA utilization. Based on these findings, this study suggests measures for efficient FTA utilization for companies that want to utilize FTAs. Additionally, FTA utilization has a positive impact on export performance. In other words, the extent to which companies utilize the signed agreements has a positive impact on their performance. Based on these results, this study identifies the characteristics of companies that want to utilize FTAs and proposes measures for future efficient FTA utilization. Originality/value - This study has confirmed that in order for companies to utilize FTAs, they must meet the requirements of the FTA. To this end, the study has concluded that it is important to manage and address internal factors such as Origin Management Competency, Information Acquisition Competency, contract Management Competency, and Commitment to Export to increase FTA utilization. Based on these results, it can be confirmed that it is essential for companies to have an understanding and management of the internal factors that satisfy the requirements of the FTA in order to utilize the FTA.

• 인간식물환경학회지
• /
• 제22권6호
• /
• pp.665-676
• /
• 2019

The Korean society is currently showing a decrease in the child population and a rapid increase in the elderly population due to low birth rates and aging, but the current park system does not reflect the changing population structure. This study aimed to find ways to plan and promote use of senior-friendly parks for the aging society. The results are as follows. First, the elderly mostly gathered in Tapgol Park and Jongmyo Park which were accessible to subways and close to amenities and traditional markets. The elders usually gathered around buffer zones or green spaces set up to protect cultural heritages. Second, many elderly users were observed in Osolgil Silver Park and Sinteuri Park which were renovated with senior-friendly concept. These parks were recognized as places that the elderly people could visit without minding users of other generations because the elderly users were ensured by words such as 'seniors only' or 'senior-friendly'. Third, the importance of the locational conditions for the senior-friendly parks should be mentioned. A senior-friendly park must be located in an urban center to have convenient access to transportation, secure large green spaces, and make elderly users feel at ease with social connectivity when they use the amenities there. Fourth, the survey results showed that elderly people visited parks to exerciseand take a walk (track),by age, older age groups visited the park to socialize with other elders around their age. Fifth, the most desired facilities for constructing senior-friendly parks were fitness equipment, and sports facilities like a trail, track, and gateball field, and in some cases, vegetable gardens and indoor rest area to avoid wind in cold weather.

• Steel and Composite Structures
• /
• 제47권5호
• /
• pp.551-568
• /
• 2023

In this research, a new two-dimensional (2D) and quasi three-dimensional (quasi-3D) higher order shear deformation theory is devised to address the bending problem of functionally graded plates resting on an elastic foundation. The displacement field of the suggested theories takes into account a parabolic transverse shear deformation shape function and satisfies shear stress free boundary conditions on the plate surfaces. It is expressed as a combination of trigonometric and exponential shear shape functions. The Pasternak mathematical model is considered for the elastic foundation. The material properties vary constantly across the FG plate thickness using different distributions as power-law, exponential and Mori-Tanaka model. By using the virtual works principle and Navier's technique, the governing equations of FG plates exposed to sinusoidal and evenly distributed loads are developed. The effects of material composition, geometrical parameters, stretching effect and foundation parameters on deflection, axial displacements and stresses are discussed in detail in this work. The obtained results are compared with those reported in earlier works to show the precision and simplicity of the current formulations. A very good agreement is found between the predicted results and the available solutions of other higher order theories. Future mechanical analyses of three-dimensionally FG plate structures can use the study's findings as benchmarks.

• 한국문헌정보학회지
• /
• 제57권4호
• /
• pp.263-287
• /
• 2023

본 연구는 공공도서관의 효율적인 갤러리 설치·운영 방안을 모색하는데 그 목적이 있다. 연구를 위해 문헌 및 현장 사례 조사, 인터뷰 방법을 사용하였다. 국내 12개 지자체의 15개, 해외 3개국 11개 도시의 11개 공공도서관 갤러리를 조사·분석하였다. 국내 갤러리 운영 관계자 등 22명을 인터뷰하였고, 이 중 21명(95.5%)이 공공도서관의 갤러리 운영이 필요하다고 하였다. 효율적인 갤러리 운영을 위해 다음과 같이 제안한다. 첫째, 도서관의 상황에 따라 큐레이터를 배치한다. 둘째, 최소한 55m² 이상 규모의 갤러리를 설치한다. 셋째, 적절한 규모의 예산을 편성한다. 넷째, 가급적 외부 전문가의 심사에 따라 갤러리 대관 요청을 심사하고 공간을 시민들에게 무료로 대관한다. 다섯째, 운영 매뉴얼 및 규정을 만들어 활용한다. 여섯째, 갤러리는 도서관이 직접 운영한다.