• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3143-3147
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• 2012

Background: Previous studies investigating the association of physical activity with risk of lung cancer reported conflicting results. In order to update and improve available evidence on any link, a meta-analysis was performed. Method: We searched the PubMed database for prospective cohort studies investigating the relation of physical activity with risk of lung cancer. The pooled relative risk (RR) with its 95% confidence intervals (95%CI) was used to assess the association. Results: We included 14 prospective studies with a total of 1,644,305 participants, with 14,074 incident lung cancer cases documented during follow-up. Meta-analysis of all 14 studies suggested both high and medium levels of physical activity to be associated with decreased risk of lung cancer compared to the reference group with low level of physical activity (for high level, RR = 0.77, 95%CI 0.73-0.81, P < 0.001; for medium level, RR = 0.87, 95%CI 0.83-0.90, P < 0.001). Subgroup analyses by gender found obvious associations in both men and women. No publication bias was observed. Conclusion: Our findings suggest that high and medium levels of physical activity have a beneficial effect on lung cancer by reducing the overall risk of tumour development among both men and women.

• 복식
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• 제62권6호
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• pp.182-199
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• 2012

The purpose of this study is to analyze the actual status of costume exhibitions displayed in architectural structures heritage today to examine if they play proper roles as visual materials and suggest the necessity of post-management for comfortable viewing. This is significant in that it makes costume exhibitions function as educational culture contents to let Korean and also foreign viewers know of our costume culture properly. As a research method, the database of the Office of Cultural Properties homepage was used to extract anything related to the lives of figures during the Chosun Dynasty among the architectural structures heritages in Seoul, Incheon, and Gyeonggido. By doing so, the costume exhibitions were able to be examined among them. With field investigation and interviews of related institutions, this study examined the current status of costume exhibitions, planning of exhibitions, and post-management. Also, they found costume exhibitions that were not right for the era, and suggested ways that were more appropriate for them. The results of this study were as follows : First, according to the third selection results, there were only six among 71 places where three districts of the architectural structures heritage were present. This is a very small quantity of places when compared with the total number of architectural structures heritage. Second, as a result of the current condition investigation, the costume exhibition in the Architectural Structures Heritage is not nearly enough for a historical investigation, and almost all polluted costumes were not displayed in suitable environments for an exhibition. Therefore, qualified managers who have expertise in exhibition planning were needed to be trained to do a post-management follow up. Furthermore, it is important to systematically reorganize post-management methods. Third, the two selected places(Haepung-buwongun-yuntaegyeong-jaesi and Sunaedong-gaok) were thought not to be right for the era among the six places with costume exhibitions, and suggestions such as flat-drawing and illustration were made.

• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3419-3423
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• 2015

Background: Liposarcoma of the spermatic cord is rare and frequently misdiagnosed. The standard therapeutic approach has been radical inguinal orchiectomy with wide local resection of surrounding soft tissues. The current trend of organ preservation in the treatment of several cancers has started to evolve. Herein we present our testis-sparing surgery experience in the treatment of spermatic cord liposarcoma and a pooled analysis on this topic. Materials and Methods: Clinical information from patient receiving organ-sparing surgery was described. Clinical studies evaluating this issue were identified by using a predefined search strategy, e.g., Pubmed database with no restriction on date of published papers. The literature search used the following terms: epidemiology, surgery, chemotherapy, radiotherapy, testis sparing surgery, spermatic cord sarcomas/liposarcomas. Results: Patient received a complete excision of the lesion, preserving the spermatic cord and the testis. The final pathological report showed a well differentiated liposarcoma with negative surgical margins and no signs of local invasion. After 2-year of follow-up, there was no evidence of local recurrence. Since the first case reported in 1952, a total of about 200 well-documented spermatic cord liposarcoma cases have been published in English literature. Among these patients, only three instances were reported to have received an organ-sparing surgery in the treatment of spermatic cord liposarcoma. Conclusions: Radical inguinal orchiectomy and resection of the tumor with a negative microscopic margin is the recommended treatment for liposarcoma of the spermatic cord. But for small, especially well-differentiated, lesions, testis-sparing surgery might be a good option if an adequate negative surgical margin is assured.

• Asian Pacific Journal of Cancer Prevention
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• 제15권2호
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• pp.867-870
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• 2014

Purpose: This study used receiver operating characteristic curve to analyze Surveillance, Epidemiology and End Results (SEER) ependymoma data to identify predictive models and potential disparity in outcome. Materials and Methods: This study analyzed socio-economic, staging and treatment factors available in the SEER database for ependymoma. For the risk modeling, each factor was fitted by a Generalized Linear Model to predict the outcome ('brain and other nervous systems' specific death in yes/no). The area under the receiver operating characteristic curve (ROC) was computed. Similar strata were combined to construct the most parsimonious models. A random sampling algorithm was used to estimate the modeling errors. Risk of ependymoma death was computed for the predictors for comparison. Results: A total of 3,500 patients diagnosed from 1973 to 2009 were included in this study. The mean follow up time (S.D.) was 79.8 (82.3) months. Some 46% of the patients were female. The mean (S.D.) age was 34.4 (22.8) years. Age was the most predictive factor of outcome. Unknown grade demonstrated a 15% risk of cause specific death compared to 9% for grades I and II, and 36% for grades III and IV. A 5-tiered grade model (with a ROC area 0.48) was optimized to a 3-tiered model (with ROC area of 0.53). This ROC area tied for the second with that for surgery. African-American patients had 21.5% risk of death compared with 16.6% for the others. Some 72.7% of patient who did not get RT had cerebellar or spinal ependymoma. Patients undergoing surgery had 16.3% risk of death, as compared to 23.7% among those who did not have surgery. Conclusion: Grading ependymoma may dramatically improve modeling of data. RT is under used for cerebellum and spinal cord ependymoma and it may be a potential way to improve outcome.

• Asian Pacific Journal of Cancer Prevention
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• 제14권9호
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• pp.5061-5065
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• 2013

Background: Oral tongue squamous cell carcinoma (OTSCC) is the most common cancer diagnosed within the oral cavity worldwide. Many studies in India report OTSCC ranking among the top two most common subsites within the oral cavity. India is often labeled the oral cancer capital of the world. The incidence of tongue cancers in the population-based cancer registry (PBCR) of Chennai is showing an increasing trend. A majority of the oral cavity cancers (85%) in our cancer center present in advanced stages (III and IV). In contrast, early tongue cancers (stages I and II) constitute nearly 45% of all OTSCCs. Aim: The aim of this study was to analyze the clinical profile and epidemiological trends in our early stage tongue cancer patients with an emphasis on tobacco and alcohol habits. Materials and Methods: This retrospective analysis was based on a prospectively collected database of 458 consecutive early stage OTSCC in-patients at a tertiary care oncology centre in Chennai between 1995 and 2008. Results: Our study suggests that the earlier trends have clearly changed whereby nearly half of our patients are now never-tobacco users. The findings of the study indicate that a majority of the patients were never alcohol users (86.4%) and nearly half of them were never tobacco users (49.3%), and they had the best survival outcomes. This increasing trend of OTSCC among non-tobacco users is in contrast to our earlier experience of tongue cancer more than five decades ago.The median age of patients in our study was 53.3 years; the male to female ratio was approximately 2:1. The median follow up for the 458 patients was 53 months. Conclusions: Our study importantly as well as interestingly shows a conspicuous absence of association with the traditional risk factors, tobacco and alcohol.

• 한국습지학회지
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• 제14권4호
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• pp.581-589
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• 2012

비점오염원은 유역 및 지역의 토지이용 형태별로 강우유출수의 유출특성이 다양하고, 강우시 지표면의 각종 오염물질들이 도시하천으로 유입되어 수질에 심각한 영향을 미치고 있다. 본 연구에서는 도시지역을 주택 및 공단구역으로 구분하여 강우유출수의 유출특성을 파악하고자 오염물질별 EMC를 산정하였다. 분석 결과 강우시 주택 및 공단지역의 비점오염원은 강우초기에 유출수의 농도가 급격히 증가한 후 서서히 감소하는 초기세척현상이 발생하였으며, 초기우수의 제어가 필요하였다. 향후 장기적인 강우사상 및 수질조사 자료의 축척, GIS를 이용한 토지이용형태, 지형 및 지질특성의 자료 축척 등 지속적인 연구가 필요할 것으로 판단된다.

• Journal of Preventive Medicine and Public Health
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• 제40권3호
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• pp.213-217
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• 2007

Objectives : This study aimed to calculate the survival rates of cancer patients in Jeju Island residents from 2000 to 2001, based on their major primary sites of occurrence. Methods : Data were extracted from the database of the Jejudo Cancer Registry (JCR). The eligible population comprised 2,382 cancer cases, whose cancers were diagnosed from 1 January 2000 through 31 December 2001. Of the eligible population, 1,438 patients with 5 major cancers defined by the level of incidence rates were selected as the study participants. The period of survival for each case was calculated from the date of first diagnosis to the date of death, or the end of follow-up, i.e., 31 December 2003. The observed survival rates (OSR) and relative survival rates (RSR) were calculated according to sex, age-group, and primary sites of occurrence. Results : The 3-year OSR and RSR in 5 major cancers were higher in women than in men except 75 year-old over group. The 3-year RSR of stomach, colorectum, liver, and lung in both sexes were 61.0%, 62.6%, 24.7%, and 22.8%, respectively. The respective rates in JCR showed some statistically significant differences from those in the Korea Central Cancer Registry (KCCR). Conclusions : These results would suggest some clues about prognostic factors of major cancers in Korean, and could apply to planning and evaluating of cancer control strategies in Jeju Island.

• 보건행정학회지
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• 제27권3호
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• pp.247-255
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• 2017

Background: South Korea has experienced problems with excessive pharmaceutical expenditures. In 2010, the South Korean government introduced an outpatient prescription incentive program to effectively manage pharmaceutical expenditures. Therefore, we examined the relationship between the outpatient prescription incentive program and pharmaceutical expenditures. Methods: We used data from the Korean National Health Insurance claims database, which included medical claims filed for 22,732 clinics from 2011-2014 to evaluate associated pharmaceutical expenditures. We performed multiple regression analysis and Poisson regression analysis using generalized estimating equation models to examine the associations between outpatient prescription incentives and the outcome variables. Results: The data used in this study consisted of 123,392 cases from 22,372 clinics (average 5.4 periods follow-up). Clinics that had received outpatient prescription incentives in the last period had better cost saving and Outpatient Prescribing Costliness Index (OPCI) (received: proportion of cost saving, ${\beta}=6.8179$; p-value < 0.0001; OPCI, ${\beta}=-0.0227$; p-value < 0.0001; reference = non-received). Moreover, these clinics had higher risk in the provision of outpatient prescription incentive (relative risk, 2.772; 95% confidence interval, 2.720 to 2.824). The associations were higher in clinics that had separate prescribing and dispensing programs, or had professional staff. Conclusion: The introduction of an outpatient prescription incentive program for clinics effectively managed problems with rapid increases of pharmaceutical expenditures in South Korea. However, the pharmaceutical expenditures still increased in spite of the positive impact of the outpatient prescription incentive program. Therefore, healthcare professionals and health policy makers should develop more effective alternatives (i.e., for clinics without separate prescribing and dispensing programs) based on our results.

• 방사성폐기물학회지
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• 제1권1호
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• pp.1-10
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• 2003

1992년 리우 환경개발회의에서 채택된 Agenda 21에서 방사성폐기물의 안전관리를 위한 정책방향이 결정된 후, 국제연합은 방사성폐기물 안전관리를 지속 가능한 발전의 범위에 포함하여 국제원자력기구의 주관 하에 관련 지표의 개발 및 적용을 추진하고 있다. 2002년 국제원자력기구는 방사성폐기물관리에 관한 지속가능 발전지표를 확정하고 현재 운영중인 방사성폐기물 데이터베이스 시스템인 NEWMDB와 연계하여 회원국의 방사성폐기물관리 체계 및 현황을 정량적인 지표로 평가할 예정이다. 본 논문에서는 방사성폐기물에 관한 지속가능 발전지표의 도입근거와 적용상의 한계점을 분석하고, 국제원자력기구가 제시한 지표의 평가방법과 표준화된 절차를 도식화하였다. 도출된 평가절차에 따라 우리나라를 포함한 주요 국가의 방사성폐기물관리 체계 및 현황자료를 이용하여 각 국의 방사성폐기물관리에 관한 지속가능 발전지표를 평가하고 그 결과를 비교 분석하였다. 또한 지표의 향상을 통해 국내 방사성폐기물관리의 지속 가능성을 제고할 수 있는 방안을 도출하였다.

• 한국보건간호학회지
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• 제22권1호
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• pp.62-73
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• 2008

Purpose: To examine the outcomes of a smoking cessation clinic at a public health center, in Hwasung city in 2006 and to examine the perceptions of the users regarding the clinic services. Method: 620 smokers who visited the smoking cessation clinic from January, 2006 to November, 2006 were enrolled. An instrument developed by the researcher was used to collect their perceptions. The instrument comprised 24 questions, on a 5-point Likert scale investigating the clinic services in terms of counseling time, environment, readiness of the counselors, counseling information, campaign method, medication use, and follow-up services. The general characteristics of the participants were collected from the database developed by the Ministry of Health & Welfare. The data were analyzed with frequencies, percentage, mean and standard deviation methods. Results: The outcomes of the smoking cessation clinic in Hwasung city in 2006 showed some limitations in terms of low-income group, female smokers, and young adult smokers. Conclusion: Strategies for solving these limitations were necessary to increase the effectiveness of the smoking cessation clinic. Clinic services focused on cognitive-behavioral therapy needed to be developed in accordance with chemotherapy. More effective publicizing campaigns of the clinic services also needed to be developed for more people to know about the clinic. Strategies to increase the accessibility for the people living far from the clinic were also necessary. Assessment of the smokers who did not visit clinic was also recommended in order to determine their intentions, or barriers to visit the clinic.