• Journal of Physiology & Pathology in Korean Medicine
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• v.30 no.4
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• pp.229-235
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• 2016

Sasa borealis has long been used in folk remedies and traditional Korean medicine for analgesic, sedative and anticarcinogenic purposes. To excavate novel natural compounds for treating obesity, we separated leaf and stem and fractionated. We screened phenolic contents, anti-oxidative and anti-inflammatory properties with the fractions. Dichloromethane (DCM) and ethyl acetate (EA) fraction from both leaf and stem exhibited high anti-oxidative properties demonstrated by DPPH, ABTS assay in accordance with their phenolic contents. In addition, DCM and EA fraction from leaf inhibited nitric oxide (NO) production as well as inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in Raw 264.7 cell. Finally, DCM and EA fraction from both leaf and stem significantly inhibited 3T3-L1 preadipocyte differentiation and decreased intracellular lipid level. These results suggest that DCM and EA fraction from Sasa borealis may contain therapeutic agent for obesity by attenuating inflammation and oxidative stress.

• Korean Journal of Pharmacognosy
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• v.32 no.4 s.127
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• pp.311-315
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• 2001

The root of Astragalus membranaceus Bunge (Leguminosae), which has been used for the treatment of hypertension, chronic hepatitis, duodenal ulcers, chronic nephritis and promotion of immunity in folk remedies. Cyclooxygenase (COX-2) is responsible for the production of large amounts of proinflammatory prostaglandins (PGs) at the inflammatory site. Thus, a logical approach to the treatment of inflammatory disease should involve the inhibitors of COX-2. To develop new COX-2 inhibitors from natural products, Astragali Radix was screened by inhibiting prostaglandin $E_2(PGE_2)$ generation in the culture medium using enzyme immunometric assay. Two isoflavone glycosides, $7,2'-dihydroxy-3',4'-dimethoxyisoflavan-7-O-{\beta}-D-glucoside$ and $calycosin-7-O-{\beta}-D-glucoside$ isolated from Astragali Radix inhibited COX-2 activity.

• Child Health Nursing Research
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• v.15 no.4
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• pp.350-358
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• 2009

Purpose: This study was done to better understand how sick children and their families define chronic illness; what behaviors they used for managing chronic illness; and how they perceived the socio-cultural context of Korea. Methods: This study was a secondary analysis of qualitative studies. Articles on children with a chronic illness and their families located in electronic databases were selected for review. Twenty one qualitative studies were reviewed. Qualitative studies that had used an analysis tool, the Family Management Style Framework were reviewed. Results: Children with chronic illness and their families tended to accept illness as a negative outcome and thought that they were deprived of the context of normality. In the traditional Korean family style, parents-in-law demand absolute obedience from their daughter-in-law, leading to a conflict between the two parties, which, in turn, may have negatively affected their perceptions of chronic illness. Western and oriental medical treatments were used, and participants sought an array of folk remedies. Conclusion: Culturally specific findings can help to better understand the difficulties faced by children with a chronic illness and their families and can provide invaluable input into the development of culturally appropriate and sensitive nursing interventions.

• Korean Journal of Pharmacognosy
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• v.26 no.2
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• pp.139-147
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• 1995

Crinum asiaticum var. japonicum is a wild plant growing only in Jeju-island, Korea, and in Japan. The whole part of this plant has been known to have the pharmacological actions such as analgesic, anti-inflammatory, platelet-aggregation inhibitory, antitussive, and expectorant. With these assumed actions, the leaves (Crinum folium) of this plant has been used in the folk remedies for arthritis and arthralgia. There is, however, no scientific evidences for the pharmacological actions of Crinum asiaticum var. japonicum. In the present study, the analgesic, anti-inflammatory, and platelet-aggregation inhibitory actions of Crinium folium were evaluated using writhing test, tail-flick test, carrageenin antiedema test, in vitro thromboxane $B_2$ quantitation assay and in vitro platelet aggregation test. In order to obtain the partially purified fraction whose pharmacological action is excellent, the methanol extract of Crinium folium was fractionated consecutively into four biological fractions such as ether, ethyl acetate, butanol, and water fractions and their pharmacological actions of the fractions were investigated. Putting our results together, Crinium folium, especially ethyl acetate fraction was proven to have significant analgesic, anti-inflammatory and platelet-aggregation inhibitory actions by inhibition of prostanoids biosynthesis as one of its mechanism of action.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.1
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• pp.39-49
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• 2004

This article will introduce the changes of the historiography of the Chinese medicine which have been made during the last several decades. These will be described with the changes in the image of the Chinese medicine that has been occupied in our mind. We regard Chinese medicine as a rational knowledge system which is based on the theory of Yin-Yang and Five phases. Therefore we draw a dear line of demarcation between Chinese medicine and irrational cure means such as religious prayer, charms and folk remedies which have no theoretical background. We also think the medical lineages continue virtually uninterrupted over the whole time of the history of Chinese medicine that began from Huangdineijing(皇帝內徑) and Shanghanlun(傷寒論). And we consider Chinese medicine as a sort of science, and suppose there has been one universal and homogeneous medical system in the mainland China. This image, however, has been changing rapidly. These changes come from the join of externalists who were trained as historian not physician, for studying the history of Chinese medicine, and the methodological innovations of historiography which was influenced by the methodologies of anthropology, social history, cultural history and the discourse of postmodemism.

• Korean Journal of Acupuncture
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• v.28 no.4
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• pp.137-145
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• 2011

Objectives : This research dealt with the content of the hot medicinal compress technique in Donguibogam in order to develope the hot medicinal compress technique as a new therapy technique. Methods : In this research, we searched for the hot medicinal compress treatment in Donguibogam. Results : The hot medicinal compress technique mainly cures the diseases on the body surface and it can be applied to digestive troubles and gynecologic diseases. The hot medicinal compress technique is operated mainly at wound around the affected parts and it is applied to the constitutional symptom at the abdominal region. In the hot medicinal compress technique was used much more with medication, and the herbs used in the treatment consists of hot tastes and the warm characteristics. In the hot medicinal compress method with direct heating the herbs was mainly used. Conclusions : The hot medicinal compress technique is considered as treatment which can be utilized easily and it can be used an easy and useful self-treatment.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.1
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• pp.83-88
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• 2020

Objectives : In traditional Korean medicine literature, Succium(琥珀) is known to be effective in eliminating edema. However, pumpkins are misused in folk remedies to manage edema, because succium and pumpkin is homophony to 'Hobak' in Korean. The purpose of this study is to report the effects of Succium decoction on two patients with edema after plastic surgery. Methods : We treated two patients with edema after plastic surgery using Succium decoction. Numeric rating scale (NRS) of edema, photograph of changes in edema before and after treatment were analyzed to evaluate the effects of treatment. Results : After 2 weeks of administration, NRS for facial edema decreased from 5 to 3 and 2 to 1, respectively. Photograph of edema decreased after treatment, and there were no adverse events. Conclusions : This case report suggests that Succium decoction can be effective in treating edema after plastic surgery.

• YAKHAK HOEJI
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• v.39 no.6
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• pp.600-609
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• 1995

Studies on the pharmaco-constituents from the leaves of Cercts chinensis which have been used for the treatment of inflammation, contusion, dilated blood, pain of heart and stomach, edema, etc. in Korean folk remedies were carried out. Dried leaves of the plant were extracted with MeOH. The MeOH extract was suspended in distilled water and subsequently fractionated with $Et_{2}O$ and n-BuOH. From the $Et_{2}O$ and n-BuOH fractions, six phenolic compounds were isolated and identified as myricitrin($C_{21}H_{20}O_{12}, {\;}m.p.{\;}199~200^{\circ}$. $4myricetin-3-O-{\alpha}-L-rhamnopyranoside$), kaempferol($C_{15}H_{10}O_{6}, {\;}m.p. 276^{\circ}$), quercetin($C_{15}Ha_{10}O_{7}, {\;}m.p.{\;}313~314^{\circ}$), quercitrin ($C_{21}H_{20}O_{12}, {\;}m.p.{\;}176~178^{\circ}, {\;}quercetin-3-O-{\alpha}-L-rhamnopyranoside$), gallicin ($C_{8}H_{8}O_{5}, {\;}m.p.{\;}202~203^{\circ}$. methyl gallate), gallic acid ($C_{7}H_{6}O_{5}, {\;}m.p.{\;}260~265^{\circ}) through their physico-chemical data and UV, IR, EI-MS, $^{13}C-NMR$, and $^{1}H-NMR$ analysis with authentics.

• Korean Journal of Oriental Medicine
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• v.4 no.1 s.4
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• pp.1-25
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• 1998

$\ulcorner$Aheuichaulyo御醫撮要$\lrcorner$ was known to be published by Choi Jong-jun崔宗峻 in Korea高麗 Dynasty(A.D.1226), however its original copy is not available at the present. It was thought that Korean folk medicine and the remedies were recorded in this book, and these were recorded in $\ulcorner$Euibangyoochui醫方類聚$\lrcorner$ published in Chosun 朝鮮 dynasty(1445). $\ulcorner$Euibangyoochui$\lrcorner$ is called a treasure-house of the knowledge of traditional oriental medicine which contains over 50,000 prescriptions and enormous amount of medical information. The restoration of $\ulcorner$Aheuichaulyo$\lrcorner$was possible during the process of establishment of data base work of $\ulcorner$Euibangyoochui$\lrcorner$. $\ulcorner$Aheuichaulyo$\lrcorner$ was restored as 131 chapters mainly from the related contents of $\ulcorner$Euibangyoochui$\lrcorner$ and partially from the contents of $\ulcorner$Hyangyakjipsungbang鄕藥集成方$\lrcorner$ and $\ulcorner$Boonmoononyukyihaebang分門瘟易解方$\lrcorner$ for the supplement.

• Journal of Veterinary Clinics
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• v.24 no.2
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• pp.125-129
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• 2007

Artemisia capillaris THUNB is a perennial herb that belongs to the family Compositae spp and the most common plant among the various herbal folk remedies used in treatment of abdominal pain, hepatitis, chronic liver disease, jaundice and coughing in Korea. This experiment was conducted to investigate the inhibitory effects of orally administrated Artemisia capillaris extracts on the pathogenic bacteria in 200 ICR mice. The experimental groups showed inhibitory effects on the bacteria in $1{\sim}3$ days after inoculation. After 21 days of inoculation, no viable bacterial cells appeared in the feces of both experimental groups while they did appear in the control group. The results of these studies indicate Artemisia capillaris extract exhibited excellent antimicrobial and inhibitory effects on the food poisoning pathogenic bacteria; S. enteritidis, E. coli O157:H7, L. monocytogenes and S. aureus.