• 음성과학
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• 제15권2호
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• pp.89-97
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• 2008

There is a number of clinical conditions that affect directly or indirectly the physical properties of the vocal folds and thereby the pressure waveforms of elicited sounds. If the relationships between the clinical conditions and the voice quality are sufficiently reliable, it should be possible to detect these diseases or disorders. The focus of this paper is to determine the set of features and their values that would characterize the speaker's state of vocal folds. To the extent that these features can capture the anatomical, physiological, and neurological aspects of the speaker they can be potentially used to mediate an unobtrusive approach to diagnosis. We will show a new approach to this problem supported with results obtained from two disordered voice corpora.

• Archives of Plastic Surgery
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• 제40권3호
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• pp.256-258
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• 2013

Deepening of the nasolabial crease is an esthetically unpleasing aging phenomenon occurring in the midface. Various treatment modalities have been introduced to improve the appearance of prominent nasolabial folds, all of which have pros and cons. Currently, a minimally invasive technique using synthetic dermal fillers is most commonly used. A simple and easy subcision procedure using a wire scalpel has also been used and reported to be effective for prominent nasolabial fold correction, with minimal complications. As an alternative to the wire scalpel, we used a 20-gauge metal type spinal needle cannula (Hakko Co.) and 4-0 Vicryl suture (Ethicon Inc.) for subcision of nasolabial folds. This technique is less expensive than the use of a wire scalpel and easily available when needed. Therefore, on the basis of favorable results, our modified subcision technique may be considered effective for prominent nasolabial fold correction.

• 한국자동차공학회논문집
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• 제4권3호
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• pp.83-91
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• 1996

This paper investigates the energy absorption characteristics of thin-walled rectangular tubes. In the compact mode, the crushing process of a thin-walled tube is analyzed into 3 parts by the ratio of outward to inward fold length. The mean crush load and the half-wave folding length are determined by using minimum energy principle. The effective crush distance can be determined when half-wave folding length is known, and the number of folds is derived when crush distance is given. Thus when the crush distance is given, energy absorption capacity can be estimated with mean crush load and number of folds. And the theoretical value is proven experimentally.

• 약학회지
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• 제39권3호
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• pp.215-222
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• 1995

The in vitro antibacterial activities of new carbapenem. CRB 529, 535, 538, 545 and 550 with meropenem and imipenem were compared. CRB 529. 535, 538, 545 and 550 proved to have a broad an tibacterial spectrum. Its in vitro activity against standard 20 strains was almost the same as that of imipenem and slightly higher than that of meropenem. However. against clinical isolated P. aeruginosa, CRB 529, 535, 538, 545 and 550 showed significantly higher activity than imipenem, and also CRB 529, 535, 538, 545 and 550 showed almost the same activity than imipenem and meropenem against 82 clinical isolated strains including S. aureus (MRSA), S. aureus (MSSA), E. faecalis, E. facium, E. coli, P. aeruginosa, K. pneumonia, P. mirabiris, P. stuartii, M. morganii, C. freundii, E. cloacae, S. marcescens and A. calcoaceticus var. anitratus. The stability of CRB 529, 535, 538, 545 and 550 against porcine renal dehydropeptidase-I(DHP-1) was 10 folds higher than that of imipenem and was 3 folds higher than that of meropenem.

• 음성과학
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• 제11권4호
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• pp.223-232
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• 2004

This study investigated and compared the acoustic characteristics of the Korean stop sound [k'] in three different phonological environments: the tensified lenis stop [k'] as observed in /prek+kaci/, the fortis stop /k'/ as in /pre+k'aci/, and the fortis stop /k'/ following an obstruent as in /prek+k'aci/. The specific research question was whether or not the tensified lenis stop shares all the acoustic features with the other two kinds of fortis stops. The acoustic measures adopted in this study were H1*-H2*, VOT, length of stop closure, and $F_0$. The major findings were that the three stops showed no significant difference in all the acoustic measures except the length of stop closure. The fortis stop /k'/ following an obstruent showed significantly longer duration of stop closure than the other two stops, both of which showed no significant difference. Based on these phonetic results, this study argued that, for the proper phonological description of post-obstruent tensification, the phonological feature [slack vocal folds] of a lenis stop should be changed into [stiff vocal folds, constricted glottis] that the fortis stops should have.

• Archives of Pharmacal Research
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• 제26권6호
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• pp.446-448
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• 2003

Cystocin belongs to the class of nucleoside antibiotics from Streptomyces sp. GCA0001. Cystocin showed good activity against Gram-positive bacteria, but showed less activity against the Gram-negative bacteria. Cystocin exhibited about two to four folds higher activity than puromycin. Especially, cystocin shows relatively strong activity against Streptococcus strains. Cystocin shows quite potent antitumor activity against all of the cells tested showing $IC_{50}$ values of 0.10 to 0.14 $\mu$ g/mL. This in vitro result indicates that the cytotoxocity of cystocin is two ten folds more active than puromycin s.

• 대한후두음성언어의학회지
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• 제21권2호
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• pp.105-111
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• 2010

The vibratory or phonating surface of the human vocal folds is a complex layered structure. Benign vocal fold lesions arise primarily within the lamina propria of the vocal folds and produce dysphonia by disrupting the normal layered architecture of the phonating surface. Therefore, treatment is aimed at excision of the lesion with restoration of the normal layered architecture. The core principle of the Microflap approach is that conservative removal of submucosal pathology with preservation of overlying normal epithelium and superficial lamina propria. Microflap approach is an essential component of most phnomicrosurgical procedures and is a challenging surgical task that requires patience, appropriate instrumentation, surgical skill, and experience. The authors reviewed surgical principles of Microflap technique, instrumentation and surgical tips that could be useful for the beginners who tried to try Microflap technique for the treatment of benign vocal fold mucosal lesions.

• 대한후두음성언어의학회지
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• 제30권1호
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• pp.5-8
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• 2019

Aspiration, the entry of material into the airway below the true vocal folds, has been reported in various type of postsurgical head and neck patients. The important of correctly identifying the cause of aspiration in the head and neck surgical patient. Clearly each cause represents a different physiologic or anatomic disorder which requires different management strategy. We discuss about the cause of aspiration during head and neck treatment.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.206.1-206.1
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• 2003

From methanol extract of Acanthopnanax senticosus, six platelet anti-aggregating compounds, chiisanogenin (1), chiisanoside (2), ursolic acid (3), oleanolic acid (4), b-sitosterol (5) and daucosterol (6) were isolated. All of the isolated compounds showed dose-dependent inhibitory activities to rat platelet aggregation induced by all the agonist employed. Compound 1 showed about 50 folds higher potency than acetylsalicylic acid (ASA) on U46619 induced platelet aggregation (IC$\sub$50/ : 6.21 ${\mu}$M) and 10 ∼ 20 folds higher effect than ASA on epinephrine and arachidonic acid (AA) induced aggregation (IC$\sub$50/ ; 2.50 and 4.81 ${\mu}$M, respectively). (omitted)

• 한국지형학회지
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• 제26권4호
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• pp.97-106
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• 2019

This study aims to investigate geomorphological and geological landscapes in the Taeanhaean National Park to ensure they are well-preserved. This study discovered 390 geomorphological and geological landform resources distributed in the coastal zone of Taeanhaean National Park. Representative geomorphological and geological landforms include : sea cliffs, sea caves, wave-cut platforms, sea-stacks, pebble beaches, sand beaches, tidal flats, coastal dunes, coastal dune wetlands and folds (or micro folds) landforms. Deposition landforms are developed more and erosion and weathering landforms are less on the land zone than island zone. These landform resources vary from district to district and can be developed for geo-tourism resources. Combined efforts from the Taeanhaean National Park authorities and residents are essential to manage ecological programs using geomorphological and geological resources.