• 한국컴퓨터그래픽스학회논문지
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• 제22권3호
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• pp.11-20
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• 2016

본 논문은 모바일 기반 양안식 HMD 기기를 사용하는 마커기반의 증강현실 시나리오에서 단안영상으로부터 삼차원 입체영상을 생성하는 효과적인 기법을 제안한다. 모바일 기기의 단안카메라로는 좌안과 우안에 대해 정확한 양안시차를 제공하는 양안영상을 생성할 수 없기 때문에, 기존의 양안식 증강현실 시스템에서는 좌안과 우안에 동일한 실세계 영상을 제공하여 입체감과 몰입감이 떨어지는 문제점이 있다. 본 논문에서는 마커기반의 증강현실 시나리오에서 대부분의 사용자들이 마커를 주시한다는 가정 하에, 기존 방법에 비해 높은 입체감과 시각적 편안함을 제공하는 단안카메라 기반 3차원 입체영상 생성기법을 제안한다. 마커와 카메라의 3차원 자세정보를 통해 단안영상을 3차원 공간상에 나타내고, 사용자의 좌안과 우안에 해당하는 가상의 두 카메라를 통해 단안영상의 마커영역과 마커 위에 증강될 가상물체에 대해서 시차를 계산한다. 마커 이외의 영역은 블러 효과를 적용하여 선명도를 낮추고 양안식 HMD를 통해 입체 콘텐츠를 감상할 때 발생하는 시각적인 피로를 감소시킨다. 본 논문에서 제안하는 방법으로 생성된 3차원 입체영상이 기존 방법에 비해 높은 입체감을 제공하는지 여부를 세 가지의 사용자 실험을 통해 평가하였다. 실험결과, 본 논문에서 제안하는 방법이 기존방법에 비해 높은 입체감을 제공하고 시각적인 피로가 크지 않는다는 것, 사람의 시차와 동일한 스테레오 카메라를 통해 촬영된 영상과 유사한 현실감을 사용자에게 제공한다는 것, 그리고 영상블러를 통해 사용자의 시각적인 피로도가 감소되었다는 사실을 확인하였다.

• 한국가금학회지
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• 제49권4호
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• pp.265-272
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• 2022

Many studies on poultry have been conducted in the poultry industry to improve their important economic traits, such as egg production, meat quality, and carcass yield. Environmental changes affect the poultry's economic traits, including muscle growth. The purpose of this study is to investigate the mechanisms by which simvastatin causes muscle injury in quail muscle cells. Following treatment with various doses of simvastatin, LD50 in the quail myoblast cells was determined using a cell viability test; cell death was caused by apoptosis and/or necrosis. Thereafter, the expression patterns of the atrophy marker genes were examined via quantitative reverse-transcription polymerase chain reaction (qRT-PCR). The results showed that the transcriptional levels of the muscle atrophy marker genes (Atrogin-1, TRIM63) and the upstream genes in their signaling cascade were increased by simvastatin treatment. This indicated that simvastatin induced myogenic cell death and muscle injury via protein degradation through muscle atrophy signaling. Further studies should focus on identifying the mechanism by which simvastatin induces the protein degradation signaling pathway in quail muscle..

• 한국정보통신학회논문지
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• 제15권10호
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• pp.2279-2284
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• 2011

최근 증강현실(Augmented Reality)에 대한 관심이 증대되고, 이와 관련된 기술들이 발전함에 따라서 증강현실이 다양한 분야에 적용하려는 시도가 늘어나고 이에 대한 활용에도 기대가 모아지고 있다. 본 논문에서는 기존의 전자책과 모바일 기기 기반 증강현실 기술을 접목할 수 있는 방안을 제안하였다. PC 상에서 구현된 증강현실 콘텐츠가 pITX 임베디드 계열(CPU Intel ATOM Z530)에서 대부분 잘 동작함을 실험을 통해서 확인하였으며, 이를 바탕으로 전자책 속의 마커를 이용한 증강현실을 pITX 임베디드 계열에서 구현하였다. 그 결과 전자책에서 표현하기 어려운 콘텐츠를 동시에 제시할 수 있으며, 기존의 증강현실 콘텐츠를 그대로 이용할 수 있으므로 사용자가 현실 세계에서 가상의 콘텐츠 또는 서비스와 직접적이고 직관적인 상호작용을 손쉽게 할 수 있을 것으로 기대된다.

• 영어어문교육
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• 제17권1호
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• pp.53-80
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• 2011

The study examines how Koreans' politeness is realized in a speech act, request. The main focus is to explore underlying rationale and influence involved in their performance, not just the comparison of difference in politeness realization between native and nonnative speakers of English, as previous studies did. The study employs the DCT, an attached politeness scale questionnaire, and interviews. Twenty nine university students participated in the study. Interchangeable reading of the three data yields some interesting and valuable insights. The participants heavily rely on a few formulaic expressions to express politeness, such as interrogatives with modal verbs, please and excuse me as a politeness marker. They want to use honorific address terms that is literally translated into English, and have a belief that there are honorific words in English as in Korean. The study refers to the participants' voice on indirectness, nonverbal messages, and expressions with different connotations between English and Korean.

• Journal of Ginseng Research
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• 제36권2호
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• pp.119-134
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• 2012

As much as the popularity of ginseng in herbal prescriptions or remedies, ginseng has become the focus of research in many scientific fields. Analytical methodologies for ginseng, referred to as ginseng analysis hereafter, have been developed for bioactive component discovery, phytochemical profiling, quality control, and pharmacokinetic studies. This review summarizes the most recent advances in ginseng analysis in the past half-decade including emerging techniques and analytical trends. Ginseng analysis includes all of the leading analytical tools and serves as a representative model for the analytical research of herbal medicines.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2009년 추계학술대회논문집
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• pp.1-1
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• 2009

In this presentation, I talk about various fluid simulation methods that have been developed for computer graphics special effects since 1996. They are all based on CFD but sacrifice physical reality for visual plausability and time. But as the speed of computer increases rapidly and the capability of GPU (graphics processing unit) improves, methods for more physical realism have been tried. In this talk, I will focus on four aspects of fluid simulation methods for computer graphics: (1) particle level-set methods, (2) particle-based simulation, (3) methods for exact satisfaction of incompressibility constraint, and (4) GPU-based simulation. (1) Particle level-set methods evolve the surface of fluid by means of the zero-level set and a band of massless marker particles on both sides of it. The evolution of the zero-level set captures the surface in an approximate manner and the evolution of marker particles captures the fine details of the surface, and the zero-level set is modified based on the particle positions in each step of evolution. (2) Recently the particle-based Lagrangian approach to fluid simulation gains some popularity, because it automatically respects mass conservation and the difficulty of tracking the surface geometry has been somewhat addressed. (3) Until recently fluid simulation algorithm was dominated by approximate fractional step methods. They split the Navier-Stoke equation into two, so that the first one solves the equation without considering the incompressibility constraint and the second finds the pressure which satisfies the constraint. In this approach, the first step introduces error inevitably, producing numerical diffusion in solution. But recently exact fractional step methods without error have been developed by fluid mechanics scholars), and another method was introduced which satisfies the incompressibility constraint by formulating fluid in terms of vorticity field rather than velocity field (by computer graphics scholars). (4) Finally, I want to mention GPU implementation of fluid simulation, which takes advantage of the fact that discrete fluid equations can be solved in parallel.

• Nuclear Medicine and Molecular Imaging
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• 제41권2호
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• pp.166-171
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• 2007

GABA is primary an inhibitory neurotransmitter that is localized in inhibitory interneurons. GABA is released from presynaptic terminals and functions by binding to GABA receptors. There are two types of GABA receptors, $GABA_{A}-receptor$ that allows chloride to pass through a ligand gated ion channel and $GABA_{B}-receptor$ that uses G-proteins for signaling. The $GABA_{A}$-receptor has a GABA binding site as well as a benzodiazepine binding sites, which modulate $GABA_{A}$-receptor function. Benzodiazepine GABAA receptor imaging can be accomplished by radiolabeling derivates that activates benzodiazepine binding sites. There has been much research on flumazenil (FMZ) labeled with $^{11}C-FMZ$, a benzodiazepine derivate that is a selective, reversible antagonist to GABAA receptors. Recently, $^{18}F-fluoroflumazenil$ (FFMZ) has been developed to overcome $^{11}C's$ short half-life. $^{18}F-FFMZ$ shows high selective affinity and good pharmacodynamics, and is a promising PET agent with better central benzodiazepine receptor imaging capabilities. In an epileptic focus, because the GABA/benzodiazepine receptor amount is decreased, using $^{11}C-FMZ$ PET instead of $^{18}F-FDG$ PET, restrict the foci better and may also help find lesions better than high resolution MR. $GABA_{A}$ receptors are widely distributed in the cerebral cortex, and can be used as an viable neuronal marker. Therefore it can be used as a neuronal cell viability marker in cerebral ischemia. Also, GABA-receptors decrease in areas where neuronal plasticity develops, therefore, $GAB_{A}$ imaging can be used to evaluate plasticity. Besides these usages, GABA receptors are related with psychological diseases, especially depression and schizophrenia as well as cerebral palsy, a motor-related disorder, so further in-depth studies are needed for these areas.

• 농업과학연구
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• 제42권4호
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• pp.397-406
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• 2015

Quantitative traits are mostly controlled by a large number of genes. Some of these genes tend to have a large effect on quantitative traits in cattle and are known as major genes primarily located at quantitative trait loci (QTL). The genetic merit of animals can be estimated by genomic selection, which uses genome-wide SNP panels and statistical methods that capture the effects of large numbers of SNPs simultaneously. In practice, the accuracy of genomic predictions will depend on the size and structure of reference and training population, the effective population size, the density of marker and the genetic architecture of the traits such as number of loci affecting the traits and distribution of their effects. In this review, we focus on the structure of Hanwoo reference and training population in terms of accuracy of genomic prediction and we then discuss of genetic architecture of intramuscular fat(IMF) and marbling score(MS) to estimate genomic breeding value in real small size of reference population.

• 한국어교육
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• 제29권4호
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• pp.137-168
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• 2018

The purpose of this study is to prepare the basis for a more objective evaluation of oral fluency by comparing speech patterns of Korean native speakers and L2 Korean learners. For this purpose, the current study focused on the analysis of speech materials of the 21st century Sejong spoken corpus and Korean learner corpus. We compared the oral fluency of Korean native speakers and Korean learners based on speech rate, pause, and discourse markers. The results show that the pattern of Korean learners is different to that of Korean native speakers in all aspects of speech rate, pause, and discourse markers; even though proficiency of Korean leaners show increase, they could not reach the oral fluency level of Korean native speakers. At last, based on these results of the analysis, we added suggestions for setting the evaluation criteria of oral fluency of Korean learners.

• Bulletin of the Korean Chemical Society
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• 제30권12호
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• pp.2999-3005
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• 2009

Among the more than 120 different types of human papillomavirus (HPV), types 16 and 18 have been known to be high risk agents that cause cervical cancer. We examined, in an immuno-chromatographic analysis, the potential of using the early gene product, E7 protein, as a diagnostic marker of cervical cancer caused by HPV. We developed monoclonal antibodies specific to HPV-16 and 18 E7 proteins that were produced from bacterial cells using gene recombinant technology. For each E7 protein, the optimal antibody pair was selected using the immuno-chromatographic sandwichtype binding system based on the lateral flow through membrane pores. Under these conditions, this rapid testing assay had a detection capability as low as 2 ng/mL of E7 protein. Furthermore, since viral analysis required the host cell to be lysed using chemicals such as detergents, it was possible that the E7 protein was structurally damaged during this process, which would result in a decrease in detection sensitivity. Therefore, we examined the detrimental effects caused by different detergents on the E7 protein using HeLa cells as the host. In these experiments, we found that the damage caused by the detergent, nonylphenylpolyethylene glycol (NP-40), was minimal relative to Triton X-100 commonly used for the cell lysis. Temperature also affected the stability of the E7 protein, and we found that the E7 protein was stabilized at 4$^{\circ}C$ for about 2 h, which was 4 times longer than at room temperature. Finally, a HPV-infected cervical cancer cell line, which was used as a real sample model, was treated using the optimized conditions and the presence of E7 proteins were analyzed by immuno-chromatography. The results of this experiment demonstrated that this rapid test could specifically detect HPV-infected samples.