• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 2001년도 추계학술대회 및 정기총회
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• pp.81-81
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• 2001

The photoinducible DNA cleaving activities of bromofluoroacetophenones as a novel photonuclease were investigated. The photolytic behavior and DNA cleaving acitivity of fluorine derivative were compared with those of non-fluorine substituted compound, 4'-bromoacetophenones. Although the DNA cleaving activities of fluorine analogs were similar with those of 4'-bromoacetophenones, ο-bromo-$\rho$-fluoro derivatives gave the better DNA cleaving activities than $\rho$-bromo-ο-fluoro derivatives did.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 추계학술대회 논문집
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• pp.345-351
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• 2007

The research which it sees will confront to the coating with paint material and a coating with paint public law application of the river bridge and it will present it will sleep and it will execute, it will reach and a comparison - an analysis from the research which it tries to respect middle of special environment the polyurethane system which is a method coating with paint system and fluorine resin system, against a ceramic system it executed more an objectivity and rational fundamental data. With research method against each coating with paint evening sunlight a research investigation material and structure, it separated with spatial-temporal characteristic and economic viewpoint it executed. When considering overview from material viewpoint, fluorine resin system ceramic system polyurethane system pure with it is judged with the fact that it is excellent. There is a possibility of saying that the coefficient of friction of the fluorine resin system which uses the weapon quality zinc end coating compound ever so hard and polyurethane system is excellent ceramic system than from structure viewpoint. That fluorine resin system = polyurethane system ceramic system pure with it is excellent, it is judged from spatial-temporal characteristic viewpoint. It measures but it considered an internal troubles year grudge in the standard which becomes disturbance the place where it executes the market the expectation life person of the general bridge against 100 years the result fluorine resin system polyurethane system ceramic system which compares a materials unit cost pure with it appeared.

• 분석과학
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• 제27권3호
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• pp.167-171
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• 2014

불화수소는 유리의 식각, 금속의 녹 제거 등 산업계에서 많이 사용되는 대표적인 무기산이며 노출 시 눈, 코, 목안을 강하게 자극하고, 흡입 시 폐렴, 폐수종 기관지염을 일으키는 대표적인 유독물질에 해당하는 화학물질로 구분되어 있다. 현행 폐기물공정시험기준에는 불소화합물에 대한 함량분석방법이 마련되어 있지 않아 최근 발생된 불화수소 누출사고로 발생된 불산에 오염된 농작물, 수목 등 가연성 폐기물의 신속하고 안전한 처리방법 마련에 어려움을 겪었다. 본 연구에서는 불화수소 누출사고로 발생된 가연성 폐기물(농작물, 수목 등) 중 불소 및 불소화합물의 함량분석방법 마련을 통해 폐기물의 불산 오염여부를 판단하고 적절한 폐기물 처리방법을 제시하고, 향후 이 방법을 폐기물 관리법상에 지정폐기물에 함유된 유해물질로 불소 및 불소화합물에 대한 항목 추가 시 폐기물공정시험기준으로 활용하고자 한다.

• Bulletin of the Korean Chemical Society
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• 제19권1호
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• pp.74-78
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• 1998

Synthesis of novel 9-fluoroanthracyclines carrying L-fucose as a sugar component is described. Compound 3 containing a fluorine at the C-9 position was synthesized from an epoxide 2 and HF/Pyr (7 : 3). Bromination and hydrolysis of compound 3 resulted in synthesis of an aglycone, 9-fluoroanthracyclinone 6. The α-(1b) and β -anomers (1a) of the final product were obtained in high yields by a coupling reaction with the L-fucose.

• 청정기술
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• 제5권2호
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• pp.37-44
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• 1999

불소 함유 디올(diol)과 친수성기 함유 디올을 사용하여 수용성 불소계 폴리우레탄을 합성하여, 반응물의 조성이 합성된 폴리우레탄의 대표적 물성인 표면자유에너지와 수분산성에 미치는 영향을 조사하였다. 폴리올보다 이온성부여 디올이 분산성 향상에 효과적이었으며, 전체 폴리올(polyol)에 대한 이온성 친수성기 함유 디올의 몰 비가 0.3~0.7의 범위를 가질 때, 합성된 폴리우레탄의 수용액에 분산된 입자 지름이 610~310nm로 안정된 유화물을 형성하였다. 폴리우레탄내의 불소 함량이 10 wt%까지 증가함에 따라 표면자유에너지는 22.3 dyn/cm에서 12.6 dyn/cm로 급격히 감소하였으며, 수분산된 입자의 지름은 380 nm에서 860nm로 증가하였다. 그 이유는 낮은 표면에너지와 강한 소수성을 갖는 불소집합체의 표면 배열로써 분자 상호간의 결합력이 증가하기 때문이다. 과불소알킬기를 포함하는 매크로단량체(macromonomer)의 강한 소수성 때문에 수용성 폴리우레탄의 단점인 소수성 하락의 보완에 더 효과적이었다.

• 대한전기학회논문지
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• 제41권5호
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• pp.525-532
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• 1992

Fluorine-doped YBaS12TCuS13TOS17-xTFS1yT superconducting materials with y varing two orders of magnitude form 0.02 to 2.0 have been prepared by a sol-gel process by using metal nitrate salts, sodium hydroxide and sodium fluoride. Fluorine contents have been measured using an ion-selective electrode. All fluorine doped as reactant were found to be present in the resulted samples. From the observation of XRD it has been concluded that the samples with y 0.2 formed simply the single phase of perovskite structure, whereas those with y 0.5 yielded together some compounds such as BaFS12T, YFS13T and CuO in the resulted samples. The observation of solid state S019TF NMR has been carried out in order to check whether fluorine was actually incorporated into the lattice sites, and the experimental results revealed that the mole ratio of fluorine incorporated into the lattice sites of YBaS12TCuS13TOS17-xT was approximately 0.2 per mole of the compound. Also electrical resistivity measurement indicated that onset transition temperature has the tendency to increase slightly with increasing y in the dilute region as y 0.2.

• 대한환경공학회지
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• 제22권6호
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• pp.1127-1137
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• 2000

인산염 폐수와 불소폐수를 대상으로 각각 $La^{3+}$를 주성분으로 하는 희토수처리제와 조염화희토화합물로 제조된 수처리제를 적용하는 방안을 검토하였다. $La^{3+}$의 인산염 농도 대비 투입몰비에 따른 인산염의 제거양상을 조사한 결과, 투입몰비 0.25에서 약 50% 정도의 인산염이, 그리고 투입몰비 0.5 에서 대부분의 인산염이 제거되는 결과를 보였다. 희토수처리제에 의한 인산염 인의 제거반응은 평형에 신속히 도달하였으며, 온도증가에 따라 인산염의 제거율이 다소 감소하는 경향이 관찰되어 발열반응의 특성을 나타내었다. 희토-인산 결합체의 제타전위는 pH 5.5를 경계로 그 이하에서는 양의 값을, 그리고 그 이상에서는 음의 값을 가지는 것으로 파악되었으며 pH에 따른 제타전위 절대치의 증감과 탁도의 증감은 유사한 경향으로 변화하였다. 불소폐수에 대한 조염화희토 수처리제의 적용에 있어서는 수처리제의 투입량 중가에 따른 잔류불소 농도의 감소 및 탁도와 생생슬러지량의 증대현상이 관찰되었으며, 수처리제의 투입량이 고정된 상태에서 응집제량의 변화에 따른 불소처리효과에 대한 검토에서는 응집제의 주입량이 증가됨에 따라 잔류불소량 및 탁도는 감소하고 슬러지 발생량은 증가하는 경향이 파악되었다.

• Archives of Pharmacal Research
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• 제9권4호
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• pp.237-242
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• 1986

The Synthesis of E, E, E-12-fluorofarnesol and E, Z-6-fluorofarnesol which are key intermediates for the study of biosynthesis of some sesquiterpenes, is described. E, E-Farnesyl acetate is treated with selenium dioxide to give E, E, E-12-hydroxy farnesyl acetate, whih is transformed by DAST into E, E, E-12-hydroxy farnesyl acetate, which is transformed by DAST into E, E, E,-12-fluorofarnesylacetate. The latter compound is hydrolyzed to E, E, E,-12-fluorofarnesol. The reformatsky reaction of 6-methyl-5-hepten-2-one with ethyl bromofluoroacetate affords ethyl 2-fluoro-3-hydroxy-3, 7 dimethyl-6-octanoate. This ester is acetylated and eliminated to give ethyl (Z)-2-fluoro-3, 7-dimethylocta-2, 6-dienoate, which is transformed to allyl bromide via allylic alcohol. The allyl bromide is treated with dianion of methyl acetate to give-keto ester. The $\beta$-keto ester is converted to diethyl phosphoryloxy compound. The conjugate addition of lithium dimethylcuprate to the latter compound gives fluoro ester, which is treated with DIBAL to afford E, Z-6-fluorofarnesol.

• 한국치위생학회지
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• 제10권4호
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• pp.757-764
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• 2010

Objectives : The fluoride coating for caries prevention and strengthen enamel use NaF(sodium fluoride, Junsei Chemical Co., Ltd, Japan) 2% gel, SnF2(stannous fluoride, SIGMA-ALDRICH Gmbh, USA)8% gel and APF(acidulated phosphate fluoride, Sultan health care, USA) 1.23% gel. Methods : After put the enamel piece in these fluoride compound gel, we observed density level. And after measuring the vickers hardness, Got the following conclusions. Results : 1. After settling in the APF 1.23% during 6 days, we observed high density level of enamel surface using 250 magnification scanning microscope. The vacuum of surface packed (in) like sardines. 2. After settling in the APF 1.23% during 6 days, we observed reducing the space between the cluster of enamel surface using 50,000 magnification scanning microscope. 3. The vickers hardness change was very much on the all kinds of fluoride compound gel[2% NaF(sodium fluoride)gel, 8% SnF2(stannous fluoride) gel, 1.23% APF(acidulated phosphate fluoride)gel]. It's all because of reducing the space between the cluster of enamel surface(p<0.001). Conclusions : The vickers hardness change was very much on the all kinds of fluoride compound. It's all because of reducing the space between the cluster of enamel surface.

• 대한화학회지
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• 제48권4호
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• pp.447-450
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• 2004