• Applied Microscopy
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• v.30 no.3
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• pp.285-293
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• 2000

The present study has been carried out to investigate the effect of fluoride toxicity on the morphology as well as inorganic chemical constituents of rat teeth. Rats were administered sodium fluoride at dose of 0 ppm, 100 ppm, 200 ppm and 300 ppm at the beginning of pregnancy. Animals were perfused intravascularly with glutaraldehyde and the incisors were removed. Changes in the protein composition of the secretory and maturation enamel were investigated using polyacrylamide gel electrophoresis (SDS PAGE). And the enamel surface of incisors was examined under scanning electron microscope (SEM). Changes of protein quantities were found significantly in high levels fluoride administration for experimental groups compared with control. The SDS PAGE analysis demonstrated as follows In control group, secretory phase enamel protein, amelogenins, was detected more quantities than experimental group. The enamelin, presence in maturation phase enamel , showed more quantifies than control enamel with an increasing fluoride concentration in the drinking water. Also, the scanning electron micrographic data showed hypoplastic, tough, uneven, pitted and cracked enamel surfaces covered with granular deposits as a result of excessive intake of fluoride. From these results we conclude that high dose of fluoride administration leads to severe structural alterations on the enamel surface and these structural changes could be through defective mineralization.

• Journal of Technologic Dentistry
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• v.13 no.1
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• pp.61-78
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• 1991

Dental caries is one of the main factors to cause the teeth to be lost. Diet is the important factor in the development of dental caries. Today, Dental plaque control, Fluoride to pical application, Fissure sealing and Diet control are used to prevent dental caries. By the five day diet diary, the author surveyed the food in take of 600 infants aged from 10 to 12 in the subures of Seoul. Using the cariogenic food intake analysis form, the detergent food intake analysis form and the basic food intake analysis form, the data were collected, analysed and discussed. After discussing the results, the author concluded as follows : 1. The intake frequency of meals per day was 4.91 times, of which 2.74 times taken at meals and 2.17 times at between meals. Girls(5.00) had taken more times than boys(4.69) at meals an between meals. 2. The intake frequency of cariogenic food per day was 1.93 times, Liquid cariogenic food was taken 0.05 times at meals, and 0.58 times at between meals. Solid cariogenic food was taken 0.05 times at meals, and 0.08 times at between meals. Girls(1.67) had taken cariogenic food more times than boys(1.46). 3. The percentage of intake without detergent food of each intake time per head per day was 71.62% at meals, and 85.7% at between meals. The highest percentage was at evening meals. Boys(44.00%) had taken more detergent food than girls(56.71%). 4. Both boys and girls had the basic food intake taken enough only in 2nd group of basic food, lacking in the other 4 groups. Girls had taken the basic food comparatively more times than boys.

• Journal of Korean society of Dental Hygiene
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• v.11 no.6
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• pp.1005-1016
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• 2011

Objectives : The purpose of this study was to examine the awareness of mothers on their children's oral health and their concern for that by socio-demographic characteristics and the relationship of their awareness of methods of dental-caries prevention to their practice of the methods. Methods : The subjects in this study were 337 guardians of preschoolers at kindergartens and daycare centers. A self-administered survey was conducted from April 25 to May 27, 2011, and the collected data were analyzed by the statistical package SPSS 18.0. Results : 1.Self-rated concern for children's oral health, 87.7 percent and 12.1 percent replied, "So-so." Whether they were working or not and whether they were mainly responsible for child rearing made significant differences to that(p<.05). 2. As to subjective awareness of their children's oral health, the largest group of the mothers answered "So-so." (44.9%) The second replied that their children were in good oral health(40.5%), and the third group in poor oral health(14.2%). 3. The relationship between self-rated concern for their children's oral health and awareness of methods of caries prevention, statistically significant differences were found according to toothbrushing education and sealant(p<.05). There were no statistically significant differences in practice, but application of fluoride was the least. 4. The relationship between self-rated awareness for their children's oral health and awareness of the preventive methods of caries, there were statistically significant gaps in awareness of toothbrushing education(p<.05). In practice, statistically significant gaps were found in practice of toothbrushing education and sugar-intake restriction(p<.01). 5. In regard to the correlation between awareness and practice of the preventive methods of caries, awareness of all the factors involving toothbrushing education, sealant, application of fluoride and restriction of sugar intake had a significant positive correlation to practice of them. Better awareness led to better practice. Conclusions : In order to ensure children's successful oral health care, more authentic education of how to prevent dental caries should be offered by experts such as dental hygienists and dentists. Especially, detailed information on application of fluoride, restriction of sugar intake and pit and sealant should be provided for mothers to help their children to stay away from dental caries.

• Journal of dental hygiene science
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• v.6 no.2
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• pp.55-63
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• 2006

The purpose of this study was to provide the basic data for preventing dental caries, and maintaining and enhancing oral health. The subjects of this study were 138 male and female students who were in the 6th grade of elementary schools in Gimpo city. This study investigated the number of decayed tooth and the factors related to the number of decayed tooth, by using the results of questionnaire and oral health survey over such subjects. So, this study obtained the following conclusions. 1. For the number of decayed tooth, 'nothing(D = 0)' was the highest as 37.7%, and 'from two to three' was 23.9%, 'more than four' was 21%, and 'one' was 17.4% in order. 2. For the frequency of visiting dental clinics within the last one year, 'one to two times' was the highest as 52.2%, and the children who have not visited dental clinics even one time during one year were 23.9%. 3. For average daily tooth brushing frequency, 'two times' was the highest as 71.7%. For the use of oral health devices besides toothbrushes, 'I don't use' was the highest as 54.3%. For the experience of sealant and fluoride application, 'nothing' was the highest as 86.9% and 71.3% respectively. For the recognition on the use of fluoride dentifrice, 'I don't know' was the highest as 66.9%. 4. The socio-demographic factors related to the number of decayed tooth were mother's age, mother's background, mother's employment, and after-school fosterer(p > 0.05). 5. The oral health care factors related to the number of decayed tooth were average daily tooth brushing frequency, the use of oral health devices besides toothbrushes, and the experience of fluoride application.(p > 0.05) 6. The snack intake factors related to the number of decayed tooth were tooth care foods intake frequency and decaying foods intake frequency(p > 0.05). 7. The oral health belief item related to the number of decayed tooth was susceptibility(p > 0.05). 8. According to the results of regression analysis, the less mother was employed, the more the average daily tooth brushing frequency was, the more the tooth care foods intake frequency was, the less the decaying foods intake frequency was, and the higher susceptibility was, the lower the number of decayed tooth. 9. In order to prevent and cure early the dental caries which occur frequently in elementary school students, the establishment of oral health centers within schools should be expanded to promote tooth brushing instruction, fluoride solution rinsing, diet control, periodic oral examination.

• The Journal of the Korean dental association
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• v.12 no.10
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• pp.767-770
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• 1974

A 12 years old patient having rampant dental caries on permanent dentition has been treated under operative procedures. In addition to this operative treatment the nutritional survey and the caries activity was checked, and performed the oral hygiene instruction to the patient. As the consequences of above procedures the following results were obtained: 1. The familial history and eating habits checkings were helpful for better dental health guide and caries control. 2. The restriction of mono & disaccharide intake and topical application of 8% stannous fluoride at least two times revealed excellent control effect for recurrent dental caries.

• Journal of Korean society of Dental Hygiene
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• v.16 no.6
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• pp.849-861
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• 2016

Objectives: The purpose of the study was to investigate the relationships among snack habits, oral health practice, and oral health status in preschool children. Methods: The subjects were 209 preschool children and their mothers in Jeonbuk from March 24 to May 30, 2014. The study instruments comprised snack habits, oral health practice, and oral health status. Data were analyzed for independent t-test, one way ANOVA and hierarchical multiple regression using SPSS Win 21.0 version. Results: Higher dft index was shown in the older age (p=0.033), lower mother's education (p<0.001), lower mother's daily toothbrushing (p<0.001), check-up after tooth-brushing (p<0.001), tooth-brushing practice before sleeping (p<0.001), tooth-brushing practice after snack (p<0.001), regular dental check-up (p<0.001), fluoride and sealant for prevention caries (p<0.001), limitation of sugar snack intake (p<0.007), periodic replacement toothbrush (p=0.022). The cause of higher dft index included soda (p<0.001), yogurt (p<0.001), snack (p=0.002), bread and cake (p=0.002) and caramel and candy (p<0.001). Fruit (p<0.001), vegetable (p<0.001) and milk (p=0.004) decreased dft index. Factors affecting oral health status were tooth-brushing practice before sleeping, tooth-brushing practice after snack, regular dental check-up, fluoride and sealant for prevention caries, and intake of soda, yogurt, caramel, candy, and fruit. The explanation power of the final model was 67.6%. Conclusions: It is necessary to develop the oral health education program for the preschool children and mothers to enhance the best oral health condition.

• Journal of Industrial Convergence
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• v.20 no.7
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• pp.131-137
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• 2022

In the study, we endeavored to assess the convergence effect of Silybum marianum-derived silymarin and epidemiologically-correlated alcohol intake on vascular contractility and to determine the mechanism involved. There were few reports addressing the question whether thin or thick filament modulation is included in ethanol and silymarin-induced regulation. We hypothesized that ethanol at a low concentration and silymarin play a role in agonist-dependent regulation of vascular contractility. Denuded arterial muscles of Sprague-Dawley male rats were suspended in organ baths and isometric tensions were transduced and recorded using isometric transducers and an automatic data acquisition system. Interestingly, both silymarin and ethanol didn't encourage silymarin alone-induced inhibition in agonists-induced contraction suggesting that endothelial nitric oxide synthesis might be involved in ethanol or silymarin-induced modulation of vascular contractility and additional pathways besides endothelial nitric oxide synthesis such as ROCK inactivation might be involved in the silymarin-induced modulation of vascular contractility.

• Korean Journal of Hazardous Materials
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• v.2 no.1
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• pp.18-26
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• 2014

We analyzed the demand of competent authorities requiring adequate technical information for initial investigation of chemical accidents. Reflecting technical reports on chemical accident response by environmental agencies in the U.S. and Canada, we presented information on environmental diffusion and toxic effects available for the first chemical accident response. Hydrogen fluoride may have the risk potential to corrode metals and cause serious burns and eye damages. In case of inhalation or intake, it could have severe health effects. The substance itself is inflammable, but once heated, it decomposes producing corrosive and toxic fume. In case of contact with water, it can produce toxic, corrosive, flammable or explosive gases and its solution, a strong acid, may react fiercely with a base. In case of hydrogen fluoride leak, the preventive measures are to decrease steam generation in exposed sites, prevent the transfer of vapor cloud and promptly respond using inflammable substances including calcium carbonate, sodium bicarbonate, ground limestone, dried soil, dry sand, vermiculite, fly ash and powder cement. The method for fire fighting is to suppress fire with manless hose stanchions or monitor nozzles by wearing the whole body protective clothing equipped with over-pressure self-contained breathing apparatus from distance. In case of transport accident accompanied with fire, evacuation distance is 1,600m radius. In cae of fire, fire suppression needs to be performed using dry chemicals, CO₂, water spray, water fog, and alcohol-resistance foam, etc. The major symptoms by exposure route are dyspnoea, bronchitis, chemical pneumonia and pulmonary edema for respiration, skin laceration, dermatitis, burn, frostbite and erythema for eyes, and nausea, diarrhea, stomachache, and tissue destruction for digestive organs. In atmosphere, its persistency is low, and its bioaccumulation in aquatic organism is also low.

• Journal of dental hygiene science
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• v.1 no.1
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• pp.21-27
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• 2001

The purpose of this study was to explore some of the right directions for school dental-health education, by examining nursing students' knowledge on and attitude to the two major oral diseases in our country, dental caries and periodontal disease, as they will take charge of dental-health education and care for children in school dental-health center as sole expert health personnels after graduation. As a result of making an analysis of their knowledge and attitude, the following findings were acquired: (1) The students investigated perceived their oral cavity to tend to be healthy(36.8%) or in moderate situation(36.3%), although they had a subjective symptom for hot or cold food. (2) They thought dental caries is attributed to poor dental hygiene care(90.4%). Among them, 94.1% found toothbrushing effective for the prevention of dental caries, but just 40.2% agreed that toothbrush should be straight. (3) Those who considered fluoride effective for dental caries prevention thought the best way to use fluoride is taking fluoride-containing tap water(2.00). The second best way was fluoride mouth rinse(2.40), followed by the topical application of fluoride(2.70), use of fluoride dentifrice, and intake of fluoride(4.30) in the order named. (4) The regular examination and toothbrushing were mentioned as a way to prevent dental caries, but just toothbrushing was put in action for dental health. So their knowledge and actual attitude weren't the same. (5) They brushed their teeth for oral health(94.3%). Toothbrushing was done after breakfast(71.9%) or before bedtime(65.8%). Just 40.3% performed toothbrushing after lunch. That was implemented twice(35.7%) or three times(37.6%) a day. (6) Out of those who pointed out toothbrushing as a way to prevent periodontal diseases(84.7%), the effect of toothbrushing on the prevention of periodontitis wasn't supported by 7.1% of those who completed the course of study for the teaching profession and by 17.0% of the others who didn't. The two groups weren't of the same opinion. The above-mentioned findings suggest that the dental knowledge of the nursing students wasn't good enough to be properly responsible for school children's dental health care. In particular, there was a gap between knowledge and attitude. To improve children's poor dental health and help their oral cavity stay healthy, there is a need to activate school dental-health center, which is now in model operation, and to make the most of dental hygienists, who are educated to be a dental-health specialist, for more successful dental-health care for school children.

• Journal of Korean society of Dental Hygiene
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• v.5 no.2
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• pp.147-157
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• 2005

The purpose of this study was to assess how mothers' oral health cognition influence on dental caries status of their children. The 194 children and their mothers were selected for this study. The children were 5, 6, 7 years old in the three day care centers in Ulsan, Korea. Date were collected by oral examination on children and self-administrated questionnaire on their mothers. The questionnaire was surveyed mothers' cognition of oral health and their socio-demographic characteristics. The findings of this study were summarized as follows: 1. The higher mother's income, the lower infant's dental caries, there was significant relation. 2. There were no significant relationship between dental caries preventive cogniton, infant's preventive treatment, between-meals intake and infant's dental caries. 3. There was significant relationship between morther's toothbrushing frequency and infant's dental caries.