• Title/Summary/Keyword: fluidized bed

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Formulation of Sustained Release Granule for Venlafaxine-HCl Using Water-Insoluble Polymer (수불용성 고분자를 이용한 염산벤라팍신의 서방형 과립 설계)

  • Park, Ji-Seon;Seo, Jin-A;Jeong, Sang-Young;Yuk, Soon-Hong;Shin, Byung-Cheol;Hwang, Sung-Joo;Cho, Sun-Hang
    • Journal of Pharmaceutical Investigation
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    • v.37 no.2
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    • pp.101-106
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    • 2007
  • Venlafaxine, 1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl] cyclohexanol hydrochloride is a novel, nontricyclic antidepressant. venlafaxine is a unique antidepressant that differs structurally from other currently available. The aim ot the study was to formulate sustained-release venlafaxine granules and assess their formulation variables. It consists of two layers, venlafaxine drug layer and sustained release coating layer and manufactured by fluidized bed process. The sustained release of drug could be increased by double-control rising various components in venlafaxine drug layer and sustained-release layer. The drug-containing granules were coated with cellulose acetate, cetyl alcohol and Eudragit RS along with plastisizer such as dibuthyl sebacate as an nano-pore former The release oi venlafaxine depended on the type of Eudragit such as RS, and RL used in the formulation of controlled release layer. These results obtained clearly suggest that the sustained release oral delivery system for venlafaxine could be designed with satisfying drug release profile approved.

Carbon-free Hydrogen Production Using Membrane Reactors (막촉매반응기를 이용한 수소생산)

  • Do, Si-Hyun;Roh, Ji Soo;Park, Ho Bum
    • Membrane Journal
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    • v.28 no.5
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    • pp.297-306
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    • 2018
  • This review focused carbon-free hydrogen productions from ammonia decomposition including inorganic membranes, catalysts and the presently studied reactor configurations. It also contains general information about hydrogen productions from hydrocarbons as hydrogen carriers. A Pd-based membrane (e.g. a porous ceramic or porous metallic support with a thin selective layer of Pd alloy) shows its efficiency to produce the high purity hydrogen. Ru-based catalysts consisted of Ru, support, and promoter are the efficient catalysts for ammonia decomposition. Packed bed membrane reactor (PBMR), Fluidized bed membrane reactor (FBMR), and membrane micro-reactor have been studied mainly for the optimization and the improvement of mass transfer limitation. Various types of reactors, which contain various combinations of hydrogen-selective membranes (i.e. Pd-based membranes) and catalysts (i.e. Ru-based catalysts) including catalytic membrane reactor, have been studied for carbon-free hydrogen production to achieve high ammonia conversion and high hydrogen flux and purity.

Effects of Operating Variables on Separation Rate and Separation Efficiency in Ash Separator for Solid Fuel Chemical Looping Combustor (고체연료 매체순환연소기를 위한 회재분리기에서 분리속도 및 분리효율에 미치는 조업변수들의 영향)

  • RYU, HOJUNG;LEE, DONGHO;YOON, JOOYOUNG;JANG, MYOUNGSOO;BAE, DALHEE;PARK, JAEHYEON;BAEK, JEOMIN
    • Transactions of the Korean hydrogen and new energy society
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    • v.27 no.2
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    • pp.211-219
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    • 2016
  • To develop an ash separator for the solid fuel chemical looping combustion system, effects of operating variables such as solid injection nozzle velocity, diameter of solid injection nozzle, gap between solid injection line and vent line, vent line inside diameter, and solid intake height on solid separation rate and solid separation efficiency were measured and discussed using heavy and coarse particle and light and fine particles mixture as bed material in an acrylic fluidized bed apparatus. The solid separation rate increased as the solid injection nozzle velocity and the diameter of solid injection nozzle increased. However, the solid separation rate decreased as the gap between solid injection line and vent line, the vent line inside diameter, and the solid intake height increased. The solid separation efficiency was in inverse proportion to the solid separation rate. In this study, we could get high solid separation rate up to 2.39 kg/hr with 91.6% of solid separation efficiency.

Carbonation Behavior of Lightweight Foamed Concrete Using Coal Fly Ash

  • Lee, Jae Hoon;Lee, Ki Gang
    • Journal of the Korean Ceramic Society
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    • v.53 no.3
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    • pp.354-361
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    • 2016
  • The purpose of this study was to prepare lightweight foamed concrete by mixing coal fly ash of circulating fluidized bed combustion(CFBC) with cement, and to develop uses for recycling by analyzing carbonation behavior resulting from a change in conditions for pressurized carbonation. For concrete, CFBC coal fly ash was mixed with Portland cement to the water-binder ratio of 0.5, and aging was applied at room temperature after 3 days of curing at $20^{\circ}C$, RH 60%. For carbonation, temperature was fixed at $60^{\circ}C$ and time at 1 h in the use of autoclave. Pressures were controlled to be $5kgf/cm^2$ and the supercritical condition of $80kgf/cm^2$, and gas compositions were employed as $CO_2$ 100% and $CO_2$ 15%+N2 85%. In the characteristics of produced lightweight concrete, the characteristics of lightweight foamed concrete resulting from carbonation reaction were affirmed through rate of weight change, carbonation depth test, air permeability, and processing analysis for the day 28 specimen. Based on these results, it is concluded that the present approach could provide a viable method for mass production of eco-friendly lightweight foamed concrete from CFBC coal fly ash stabilized by carbonation.

Study on desulfurization performance of Zn-based solid sorbents at high temperature and pressure in the 0.3 bbl/d CTL(Coal-to-Liquid) process integrated with coal gasifier, F-T process and hot gas desulfurization process (석탄가스화기, F-T 공정, 건식탈황공정이 통합된 0.3 배럴/일 규모 석탄액화(CTL) 공정에서 고온, 고압 연속운전에서 아연계 탈황제의 탈황 성능 파악)

  • Park, Young Cheol;Jo, Sung-Ho;Jin, Gyoung Tae;Lee, Seung-Yong;Yi, Chang-Keun
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.06a
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    • pp.107.2-107.2
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    • 2010
  • 고온건식탈황기술은 고온고압에서 석탄가스에 함유된 황화합물을 제거하는 기술로 석탄가스화에 의해 생성된 고온의 석탄가스의 열손실을 최소화하여 열효율이 높은 기술이다. 본 연구에서는 석탄으로부터 합성원유를 생산하는 0.3 배럴/일 규모 석탄액화(CTL)공정의 연계운전을 통하여 건식탈황공정의 성능을 평가하였다. 0.3 배럴/일 규모 석탄액화공정은 석탄가스화기, 건식탈황공정, 액화공정으로 구성되어 있으며 30 atm의 고압에서 운전된다. 건식탈황공정은 석탄가스화기와 액화공정 사이에 위치하여 석탄가스화로부터 생성된 석탄가스에 함유된 황화합물을 아연계 건식탈황제에 의해 제거한 후 액화반응기로 공급하여 황화합물에 의한 촉매의 피독을 막아주는 역할을 수행한다. 본 연구에서는 기존에 개발된 두 개의 기포유동층 반응기로 구성된 탈황장치를 30 atm에서 운전이 가능하도록 수정/보완하여 실제 운전압력인 30 atm의 고압에서 연속운전을 수행하였다. 실험 결과 탈황효율은 99% 이상이며 탈황반응기 출구 황화합물의 농도는 1 ppmv 이하로 유지하였다.

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Gasification of woody biomass in a fluidized bed reactor (유동층 반응기에서 목질계 바이오매스의 가스화반응)

  • Kim, Seung-Soo;Kim, Jinsoo;Seo, Young-Hoon;Cho, Won-Jun;Baek, Young-Soon;Song, Taek-Yong
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.11a
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    • pp.102.1-102.1
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    • 2010
  • 바이오매스(Biomass)는 지구상에서 에너지원으로 이용될 수 있는 모든 식물과 미생물을 총칭하는 의미로 사용된다. 최근 바이오매스를 에너지자원화 시키는 방법으로 주목받는 열화학적 전환(Thermo-chemical conversion) 반응은 산소가 없이 혹은 희박한 조건에서 바이오매스에 열과 압력을 가하거나 공기나 수증기 등의 가스화제와 반응하여 바이오오일(Bio-oil) 및 합성가스(Syngas)로 변화하는 프로세스를 의미한다. 바이오매스로부터 바이오 DME(Di-Methyl Ether) 생산을 위한 합성가스를 제조하기 위해서 국내 산림자원을 대상으로 열분해반응 특성연구를 수행하였다. 또한 이들 물질로부터 바이오 DME 합성을 위해 최적의 합성가스 제조를 위한 타당성 연구를 수행하였다. 반응온도 $800{\sim}900^{\circ}C$에서 가스화 수율은 78~80%, 촤 수율은 17~20%, 타르 수율은 4~10%였고, 합성가스($H_2$/CO)비는 0.9~1.6였다.

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Preparation process of functional particles: III. Preparation of composite particles by rapid expansion of supercritical fluid solutions and release behavior (기능성 미분말의 제조공정에 관한 연구 : III. 초임계 분출법에 의한 복합분체의 합성과 용출특성)

  • ;;;Eiichi Abe
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.9 no.1
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    • pp.55-59
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    • 1999
  • The Rapid Expansion of Supercritical fluid Solutions (RESS) process was applied to particles coating. Microcapsules prepared by spray drying were used as the core particles, and two kinds of paraffin were used as the coating materials. Supercritical $CO_{2}$ solutions of paraffin were expanded through the short nozzle into the bed that was fluidized by air. Extraction temperature and pressure were varied at $50~120^{\circ}C$, $150~200\;kg/\textrm{cm}^2$, respectively. The thickness of theoritical coating layer ws measured, and precipitate coating layer on surface was analyzed by using SEM, FT-IR. The release behaviors of $Mg^{2+}$ ions were inspected by atomic absorbance spectrophtometer.

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Synthesis of High Purity Tungsten Oxide with Tungsten Chloride from the Chlorination of Scheelite (회중석의 염소화 생성물로부터 고순도 WO3의 합성)

  • Um, Myeong-Heon;Park, Young-Seong;Lee, Chul-Tae
    • Applied Chemistry for Engineering
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    • v.4 no.4
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    • pp.798-806
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    • 1993
  • In this study we developed the synthesis of high purity tungsten oxide from tungsten chlorides obtained by the chlorination of scheelite in a fluidized bed reactor. Within a minute of dissolution time, tungsten chlorides were almost dissolved in $H_2O_2$ solution. The proper dissolution conditions for the tungsten chlorides were as follows : $H_2O_2$ concentration 0.5%, dissolution temperature $15^{\circ}C$ and $H_2O_2$ amount to 0.5g tungsten chlorides 30ml. Under above conditions, the tungsten oxide prepared from dissolved product was identified as $WO_3$ and the purity of $WO_3$ was 99.53%.

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Solid Circulation Characteristics of Oxygen Carrier for Chemical Looping Combustion System at Ambient Temperature and Pressure (케미컬루핑 연소시스템을 위한 산소전달입자의 상온-상압 고체순환특성)

  • YOON, JOOYOUNG;KIM, HANA;KIM, JUNGHWAN;LEE, DOYEON;BAEK, JEOM-IN;RYU, HO-JUNG
    • Transactions of the Korean hydrogen and new energy society
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    • v.28 no.4
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    • pp.384-391
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    • 2017
  • Effects of operating variables on solid circulation rate were measured and discussed using two-interconnected circulating fluidized bed system at ambient temperature and pressure. OCN 706-1100 particles were used as oxygen carrier. The measured solid circulation rates increased as the lower loop seal gas flow rates and the solid height in the fuel reactor increased. Suitable operating conditions to avoid choking of the air reactor were confirmed. Continuous long-term operations of steady-state solid circulation were also demonstrated at two different conditions based on the operating window.

Electrostatic Precipitability of the Coal Fly-Ash by the Pilot Scale Test

  • Ahn, Kook-Chan;Kim, Bong-Hwan;Jang, Yang-Sik
    • Journal of Mechanical Science and Technology
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    • v.15 no.5
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    • pp.602-612
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    • 2001
  • The equation of the particle collection efficiency proposed by Deutsch has been modified through the various experiments to correct the errors caused by the assumptions made for the equation. In order to get an modified Deutsch equation that can be applied to real conditions, a pilot scale electrostatic precipitator is used. The effects of operational variables on the particle collection efficiency are evaluated. Particle resistivity, gas temperature, moisture contents in gas, gas velocity and particle concentration are used as the operational variables. Two different types of coal fly-ash obtained from the fluidized bed combustor and the pulverized coal combustor are used as test particulate to evaluate the effect of the physiochemical and electrical characteristics of the particle on the particle collection efficiency. The experimental results are fitted with the modified Deutsch equation made by Matts-Ohnfeldt and the extended Deutsch equation made by E. C. Potter to evaluate the effect of the particle characteristics and the operation conditions on the particle collection efficiency of the electrostatic precipitator.

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