• Nuclear Engineering and Technology
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• 제16권1호
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• pp.1-10
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• 1984

2상 유동에 대한 일반적인 시간과 공간에 대해 평균된 보존방정식과 jump condition을 유도했다. 단상난류 유동 방정식에 사용되는 방법을 써서, 한부분에서 순간적으로 이루어지는 평형 방정식 (local instant balance eq.)으로부터 2상유동내 단상영역에 관한 시간에 대해 평균된 방정식을 유체체적에 대해 적분하여 얻어진 결과는 공간적으로 두차례에 걸쳐 평균된다. 즉, 한 유체체적내에서 일차적으로 k번째 상의 단상영역에 대해 평균하고 다음에 k번째 상 전체체적에 대해 평균한다. 질량, 운동량 그리고 에너지 보존 방정식은 일반적인 시간과 공간에 대해 평균된 방정식으로부터 얻어진다. 이 모델의 장점은 Ishii모델, 그리고 Banerjee의 model과 비교하여 설명된다. 마지막으로, THERMIT-6S의 방정식에 포함된 가정과 근사항들에 대해 박혀둔다.

• 대한의생명과학회지
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• 제16권2호
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• pp.83-90
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• 2010

Hesperidin, a member of the flavanone group of flavonoids, can be isolated in large amounts from the rinds of some citrus species [e.g., Citrus aurantium L. (bitter orange), Citrus sinensis L. (sweet orange) and Citrus unshiu Marcov. (satsuma mandarin)], and has been reported to have anticarcinogenic, antihypotensive and antimicrobial properties. Despite the efficacy of these polyphenolic compounds as immune modulators, the effects of the flavonoids are poorly understood about allergic effect. In this study, we investigated whether hesperidin could influence on Th1 and Th2 balance. Allergic reactions included an increase in the number of eosinophils in bronchoalveolar lavage (BAL) fluid, an increase in inflammatory cell infiltration into the lung tissue around blood vessels and airways, airway luminal narrowing, the development of airway hyper-responsiveness (AHR). The administration of hesperidin before the last airway OVA challenge resulted in a significant inhibition of all asthmatic reactions. Accordingly, this study may provide evidence that hesperidin plays a critical role in the amelioration of the pathogenetic process of asthma in mice. These findings provide new insight into the immunopharmacological role of hesperidin in terms of its effects in a murine model of asthma, and also broaden current perspectives in our understanding of the immunopharmacological functions of hesperidin.

• International Journal of Naval Architecture and Ocean Engineering
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• 제9권1호
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• pp.77-99
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• 2017

Offshore oscillating water columns (OWC) represent one of the most promising forms of wave energy converters. The hydrodynamic performance of such converters heavily depends on their interactions with ocean waves; therefore, understanding these interactions is essential. In this paper, a fully nonlinear 2D computational fluid dynamics (CFD) model based on RANS equations and VOF surface capturing scheme is implemented to carry out wave energy balance analyses for an offshore OWC. The numerical model is well validated against published physical measurements including; chamber differential air pressure, chamber water level oscillation and vertical velocity, overall wave energy extraction efficiency, reflected and transmitted waves, velocity and vorticity fields (PIV measurements). Following the successful validation work, an extensive campaign of numerical tests is performed to quantify the relevance of three design parameters, namely incoming wavelength, wave height and turbine damping to the device hydrodynamic performance and wave energy conversion process. All of the three investigated parameters show important effects on the wave-pneumatic energy conversion chain. In addition, the flow field around the chamber's front wall indicates areas of energy losses by stronger vortices generation than the rear wall.

• Research in Vestibular Science
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• 제17권4호
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• pp.170-174
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• 2018

Epidural anesthesia has significantly advanced in neuraxial anesthesia and analgesia. It is used for surgical anaesthesia and treatment of chronic pain. Hearing loss during or after epidural anesthesia is rare, and it is known to occur by the change of the intracranial pressure. Cerebrospinal fluid is connected with perilymph in the cochlear and vestibule that is important to hearing and balance. If the intracranial pressure is abruptly transferred to the inner ear, perilymph can be leak, that called perilymphatic fistula, dizziness, and hearing loss can occur suddenly. We report a 65-year-old woman who presented with acute onset dizziness and hearing loss during the epidural nerve block for back pain, wherein we speculated a possibility of perilymphatic fistula as the mechanism of hearing loss and dizziness. The mechanism of dizziness and hearing loss was suspected with perilymphatic fistula.

• Journal of Nutrition and Health
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• 제50권2호
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• pp.121-132
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• 2017

Purpose: This review was performed to establish a reference intake of water for Korean (KDRI-water) adults in 2015 by examining current knowledge of the relationship between water intake and health and the general status of water intake and loss. We expect that this study will be utilized for further refinement of KDRI-water. Methods: Documents were searched using RISS, NDSL, DBPIA, CINAHL, and Pubmed with the keywords 'water intake, water supply, water ingestion, hydration, dehydration, water balance, and fluid balance'. Results: Water balance is essential for the maintenance of health. Based on this assumption, numerous studies have been performed to investigate the association of water intake with several diseases such as urolithasis, obesity, diabetes, and cancer as well as other health problems, including constipation, cognition, and fetal weight. Effects of water intake for prevention or relief of these health problems vary. Water is supplied to the body by eating foods and drinking liquids such as plain water and beverages. Metabolic water is another source of water input. Water is lost through urine, skin, respiration, and feces. KDRI-water 2015 was set by adequate intake (AI) based on water intake volume, which was the sum of water intakes from foods and fluids reported by the Korea National Health and Nutrition Examination Survey, with extra milk intake of 200 mL. AIs in some age groups were modified considering their estimated energy requirements. Conclusion: Accurate data of water intake is critically important for the establishment of KDRI-water. Therefore, improvement of systems investigating water intake is required, and more studies on the status of water intake and loss in Korean people are needed for definite KDRI-water establishment.

• Nutritional Sciences
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• 제9권2호
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• pp.124-130
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• 2006

To examine the effects of alcohol consumption on body fluid restoration and fat mobilization following exercise induced dehydration, nine healthy collegiate men ($24{\pm}2yrs,\;177{\pm}5cm,\;72{\pm}8kg,\;10.5{\pm}2.3%$ body fat) underwent three experiments. In each experiment, subjects ran on a treadmill to reduce individual body mass to $2.2{\pm}0.1%$ and consumed one of three beverages containing 0, 4, or 8% alcohol over 60 min followed by 4 hr of resting recovery. They consumed approximately 150% of weight loss $(2053{\pm}204,\;2091{\pm}149,\;and\;1943{\pm}295mL)$ and content of alcohol was $9.9{\pm}1.0(0%),\;71.9{\pm}5.1(4%)$, and $132.2{\pm}20.1g$ (8% trial). Body weight, urine volume and samples, blood samples, and thirst sensation were measured five times; at baseline, immediately after exercise, and 0, 1st, and 4th hr of recovery. Blood alcohol concentration after ingestion was $0.0{\pm}0.0(0%),\;0.1{\pm}0.02(4%)$, and $0.2{\pm}0.03%$ (8% trial). No differences in blood sodium and potassium concentrations, and urine specific gravity were noticed over time periods and trials. Thirst sensation tended to be elevated in all trials immediately after exercises and urine output was elevated during the recovery. The magnitude of changes in these variables was proportional to the alcohol concentrations, but not statistically significant. While serum osmolality was not different among trials and time periods in 0 and 4% trials, it was higher during recovery than the baseline in the 8% trial (P<0.01). Triglycerides did not change throughout the time period and among trials. Free fatty acids were elevated after exercise in all trials and 4th hr of recovery in 0% (P<0.05). Subjects' net body fluid balance at 4th hr of recovery was negatively maintained and proportional to alcohol concentrations. Only 8% trials showed a significant reduction at 1st and 4th hr of recovery compared to 0 hr. The results suggested that diuretic effect of alcohol after moderate level of dehydration appeared dose dependent, but beverage containing alcohol up to 4% did not induce impaired rehydration than alcohol free drinks. Alcohol effects on fat mobilization during recovery appeared to be minimal and the mechanism is unclear.

• 한국산학기술학회논문지
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• 제21권9호
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• pp.405-413
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• 2020

압축 유동하에서 측정된 시멘트 페이스트의 수직 응력은 변형률의 증가에 따라 변형률이 0.0003에서 0.003 사이 구간인 탄성 고체 구간과 변형률이 0.003에서 0.8 사이 구간인 변형률 경화 구간으로 나누어진다. 두 구간 중 변형률 경화 영역에서 유변학적 특성을 분석하기 위해 모델링 식이 제안되었다. 첫째, 유체 거동의 관점에서, 지수법칙 일관성 지수 m=700 및 멱지수 n=0.2를 갖는 지수법칙 비뉴토니언 모델이 적용되었다. 적용 결과는 탄성 고체 구간을 제외하고는 실험 결과와 좋은 일치를 보여주었다. 둘째, 연성 고체 거동의 관점에서 힘 평형 모델이 적용되었으며, 하중을 측정하는 센서부와 시멘트 페이스트 표면 간의 마찰 계수가 실험데이터에 반구간탐색법을 적용하여 변형률의 다항식으로 도출되었다. 적용 결과는 변형률이 0.003에서 0.3 사이 구간인 중간 영역에서만 실험 결과와 좋은 일치를 보여주었다. 따라서, 압축 유동 하의 시멘트 페이스트의 유변학적 거동은 변형률 경화 구간에서 연성 고체 거동의 관점보다는 지수법칙 비뉴토니언 유체 거동의 관점에서 실험 결과와 더 일치함을 보여주었다.

• 한국유체기계학회 논문집
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• 제5권4호
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• pp.26-31
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• 2002

The heat produced by the fission in the fuel of HANARO, 30 MW of research reactor, was transferred from the primary cooling water to the secondary cooling water through heat exchangers. The secondary cooling water absorbing the heat was circulated by secondary cooling pumps and cooled through 33 MW of cooling tower. Each capacity of the three secondary cooling pumps was fifty percent ($50\%$) of full load. The two pumps were normally operated and the other pump was standby. One of the secondary cooling pumps has often made troubles by high vibration. To release these troubles the pump shaft has been re-aligned, the pump bearing has been replaced with new one, the shaft sleeve has been replaced with new one, the shaft and the impeller have been re-balanced representatively and/or the vibration of motor has been tested by disconnecting the shaft of pump. But the high vibration of pump cannot be cleared. We find out the weight balance trouble of the assembly in which the impeller is installed in the shaft. After clearing the trouble, the high vibration is relieved and the pump is operated smoothly. In this paper, the trouble solution shooting method of secondary cooling pump is described including the reason of high vibration

• International Journal of Vascular Biomedical Engineering
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• 제2권2호
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• pp.16-26
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• 2004

The object of this study is to develop a mathematical model of the hemodialysis system including the mechanism of solute kinetics, water exchange and also cardiovascular dynamics. The cardiovascular system model used in this study simulates the short-term transient and steady-state hemodynamic responses such as hypotension and disequilibrium syndrome (which are main complications to hemodialysis patients) during hemodialysis. It consists of a 12 lumped-parameter representation of the cardiovascular circulation connected to set-point models of the arterial baroreflexes, a kinetic model (hemodialysis system model) with 3 compartmental body fluids and 2 compartmental solutes. We formulate mathematically this model in terms of an electric analog model. All resistors and most capacitors are assumed to be linear. The control mechanisms are mediated by the information detected from arterial pressoreceptors, and they work on systemic arterial resistance, heart rate, and systemic venous unstressed volume. The hemodialysis model includes the dynamics of urea, creatinine, sodium and potassium in the intracellular and extracellular pools as well as fluid balance equations for the intracellular, interstitial, and plasma volumes. Model parameters are largely based on literature values. We have presented the results on the simulations performed by changing some model parameters with respect to their basal values. In each case, the percentage changes of each compartmental pressure, heart rate (HR), total systemic resistance (TSR), ventricular compliance, zero pressure filling volume and solute concentration profiles are represented during hemodialysis.

• 한국유체기계학회 논문집
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• 제2권2호
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• pp.19-26
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• 1999

Thermal output in a nuclear power plant is verified with calorimetric heat balance on the secondary plant. The calorimetry involves the precise measurement of the feedwater flow rate. However, the correct indication of feedwater flow rate obtained by a pressure-difference measurement across a venturi can be affected by instrument errors, fouling or a poorly developed velocity profile. This can result in an inaccurate mass flow rate and consequently an inaccurate estimate of power. The purpose of this study is to develop verification methods with accuracy better than $0.5\%$ for high precision flow measurement to be used for measuring feedwater flow rate. This chemical tracer method is a testing process that uses tracers which can be applied to quantify losses in electrical output due to the incorrect measurements of feedwater flow rate. And this system has good response to the variation of the flow rate. Accuracy of better than 0.5 percent can be expected for feedwater flow measurement, providing that the system can be stabilized during the test. This methodology is applicable to other flow systems well.