• Journal of Biomedical Engineering Research
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• v.15 no.2
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• pp.143-150
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• 1994

Wall shear rate or stress is believed to be a major hemodynamic variable influencing atherosclerosis and artery-graft anastomic intimal hyperplasia. The purpose of this study is to verify the effects of radial wall motion, artery-graft compliance and diameter mismatch, and impedance phase angle on the wall shear rate distribution near an end-to-end artery-graft anastomosis model. The results show that radial wall motion of the elastic artery model lowers the mean wall shear rates under pulsatile flow condition by 15 to 20 % comparing to those under steady flow condition at the same mean flow rate. Impedance phase angle seems to have small effects on the mean and amplitude of the wall shear rate distribution. In order to study the effects of compliance and diameter mismatch on the wall shear rates, two models are studied-Model I has 6% and Model I has 6% and Model II has 11% smaller graft diameter. Divergent geometry caused by diameter mismatch near the distal sites reduces the mean wall shear rates significantly, and this low shear region is believed to be prone to intimal hyperplasia.

• International Journal of Vascular Biomedical Engineering
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• v.1 no.1
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• pp.41-47
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• 2003

The patency rates of small diameter vascular grafts are disappointing because of the formation of thrombus and intimal hyperplasia. Among the various factors influencing the success of graft surgery, the compliance and the size of a graft are believed to be the most important physical properties of a vascular graft. Mismatch of compliance and size between an artery and a graft alters anastomotic flow characteristics, which may affect the formation of intimal hyperplasia. Among the hemodynamic factors influencing the development of intimal hyperplasia, the wall shear stress is suspected as the most important one. The wall shear stress distributions are experimentally measured near the end-to-end anastomosis models in order to clarify the effects of compliance and diameter mismatch on the hemodynamics near the anastomosis. The effects of radial wall motion, diameter mismatch and impedance phase angle on the wall shear rate distributions near the anastomosis are considered. Compliance mismatch generates both different radial wall motion and instantaneous diameter mismatch between the arterial portion and the graft portion during a flow cycle. Mismatch in diameter seems to be affecting the wall shear rate distribution more significantly compared to radial wall motion. The impedance phase angle also affects the wall shear rate distribution.

• Journal of Biomedical Engineering Research
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• v.28 no.4
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• pp.455-460
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• 2007

Flow mismatch between blood and dialysate is invariably encountered during conventional hemodialysis, and this deteriorates diffusive mass transfer. A modification of a conventional dialyzer was conceived to prevent this mismatch. The modified dialyzer includes two independent blood flow regions (central and peripheral regions), which were achieved by redesigning the dialyzer cap. Resultantly, the blood stream was divided into two concentric dialyzer regions. Solutes clearances obtained using the modified dialyzers were compared with those of conventional dialyzers. Solutes clearances by conventional dialyzers were uniform, but solutes clearances by modified dialyzers were found to be dependent on the simulated blood split into dialyzer central and peripheral regions. Maximal clearances using the modified dialyzer were improved by up to approximately 7.6% for urea and 7.3% for creatinine, as compared with those of conventional dialyzers. More optimizations are required for clinical applications, but the finding that blood flowrates through central and peripheral fiber bundles can be easily regulated is encouraging.

• Animal Systematics, Evolution and Diversity
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• v.32 no.2
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• pp.105-111
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• 2016

The genetic structure of marine animals that inhabit the seashore is affected by numerous factors. Of these, gene flow and natural selection during recruitment have strong influences on the genetic structure of seashore-dwelling species that have larval periods. Relative contributions of these two factors to the genetic structure of marine species would be determined mainly by the duration of larval stage. The relationship between larval period and genetic structure of population has been rarely studied in Korea. In this study, genetic variations of cytochrome oxidase subunit I (COI) were analyzed in two dominant species on rocky shore habitats in the Korean peninsula: periwinkle Littorina brevicula and acorn barnacle Fistulobalanus albicostatus. Both species are not strongly structured and may have experienced recent population expansion. Unlike periwinkle, however, barnacle populations have considerable genetic variation, and show a bimodal pattern of mismatch distribution. These results suggest that barnacle populations are more affected by local adaptation rather than gene flow via larval migration. The bimodal patterns of barnacle populations observed in mismatch distribution plots imply that they may have experienced secondary contact. Further studies on seashore-dwelling species are expected to be useful in understanding the evolution of the coastal ecosystem around Korean waters.

• Journal of Chest Surgery
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• v.18 no.4
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• pp.771-779
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• 1985

It has been recognized that the proper matching of ventilation and perfusion within the lung is essential for the efficient exchange of gases following open heart surgery. Physiologic shunt reflects the amount of blood going to lung units with inadequate ventilation and these are also areas of the lung with adequate ventilation but inadequate blood flow. This can be quantified by measuring physiological dead space. From January to August 1985, The physiologic dead space and shunt during postoperative course had been taken in 30 patients of open heart surgery in Soonchunhyang University Hospital. Twenty cases had congenital heart disease and acquired valvular heart disease were noticed in 10 cases. The physiological dead space and shunt during postoperative periods were calculated and we made 5 items of conclusion: 1. There is high probability of ventilation-perfusion mismatch in the acquired heart disease group compared to the congenital group. 2. Duration of the CPB can exert significant influences in the physiological dead space but less in the shunt fraction. 3. There is positive relationship between Qs/Qt and Vd/Vt in the group B [CPB>90 min.] but less reliable in correlation. 4. Perfusion impairment is more significant in the diminished pulmonic blood flow group compared to the increased pulmonic blood flow [Qp/Qs>2.0] group. 5. There is no significant ventilation-perfusion mismatch within the lung during all postoperative courses.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.45 no.3
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• pp.329-334
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• 1996

Power system is becoming more and more complex and large Existing procedural programming technique can't cope with software flexibility and maintenance problems. So, Object-Oriented Programming (OOP) is increasingly used to solve these problems. OOP in power system analysis field has been greatly developed. This paper applies OOP in power flow analysis, and presents new algorithm which uses only a Jacobian to solve mismatch equations, and introduces a new sparse matrix storage method which is different from existing method. (author). 11 refs., 12 figs., 3 tabs.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2000.06a
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• pp.1667-1674
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• 2000

A new method is proposed to measure the flow rate in a pipe by multiple measurements of acoustic pressure using a microphone array. It is based on the realization that variation in flow velocity affects the change in wave number. The method minimizes measurement random errors and sensor mismatch errors thereby providing practically realizable flow rate measurement. One of the advantages of the method is that it does not obstruct the flow field and can provide the time-spatial mean flow rate. Numerical simulations and experiments were conducted to verify the utility of this method.

• Journal of Biomedical Engineering Research
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• v.13 no.2
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• pp.165-174
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• 1992

Compliance mismatch across an end-to-end anastomosis was measured In the In vitro experimental setup. A 35mm camera was used and Image process was done in Gould/ DeAnza Image processor. The results showed that compliances of Penrose tubing and synthetic PTFE grafts were In good agreement with the previously reported In vivo data. PTFE grafts exhibited a nonlinear behavior with compliance decreasing with Increasing transmural pressure, whereas the compliance of the Penrose tubing remained relatively constant within the range of the pressures in which data were obtained. The lumen cross sections at the anastomosis were affected by the suture and the mismatch In compliance between the Penrose tubing and vascular grafts. The varla~lons In the lumen dtameter at the anastomosis was more pronounced with increasing transmural pressures. From the present study, it was clearly demonstrated that the compliance of prosthetic grafts Is much lower than that of the arteries. In addition to the hemodynamlc consequences, compliance mismatch across the anastomosis has been known to lead to Increased anastomotlc and suture stresses with resultant suture line dehlscence and false aneurysm formation. Thus, there are good hemodynamic reasons to suppose that Introduction of a less compliant arterial graft Into the arterial circulation wlll be damaging and that grafts should be made to match the elastic behavior of their host arteries as closely possible.

• Wind and Structures
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• v.6 no.2
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• pp.91-106
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• 2003

The paper presents the results of 1:50 geometrical scale laboratory modeling of wind-induced point pressure on the roof of the Texas Tech University (TTU) test building. The nominal (prevalent at the TTU site) wind and two bounding (low and high turbulence) flows were simulated in a boundary-layer wind tunnel at Colorado State University. The results showed significant increase in the pressure peak and standard deviation with an increase in the flow turbulence. It was concluded that the roof mid-plane pressure sensitivity to the turbulence intensity was the cause of the previously reported field-laboratory mismatch of the fluctuating pressure, for wind normal and $30^{\circ}$-off normal to the building ridge. In addition, it was concluded that the cornering wind mismatch in the roof corner/edge regions could not be solely attributed to the wind-azimuth-independent discrepancy between the turbulence intensity of the approach field and laboratory flows.

• Nuclear Engineering and Technology
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• v.55 no.3
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• pp.1118-1124
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• 2023

Experimental study on the fluidelastic instability (FEI) of a curved tube bundle in single phase downward cross flow is investigated for the design qualification and analysis input preparation of helical coiled steam generator tubing. A 6×9 normal square curved tube array with equal and different vertical/horizontal pitch-to-diameter ratio was under-tested up to 6 m/s in term of gap flow velocity to measure the critical velocity for FEI. The critical velocity for FEI was measured at the turning point from the vibration amplitude plot along the gap flow velocity. Our test results were compared with straight tube results and published data in the design guideline. The applicability of the current design guidelines to a curved tube bundle is also assessed. We found that introducing frequency difference in a curved tube array increases the critical velocity for fluidelastic instability.