• Title/Summary/Keyword: flavnoid

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Analysis of Antioxidant Activity and Total Phenol Content and Flavonoid Content Through the Synergistic Effect of Rosa multiflora Extracts and Ascorbic Acid (찔레꽃(Rosa multiflora) 추출물과 Ascorbic Acid 의 시너지 효과를 통한 항산화 활성과 총 페놀함량 및 플라보노이드 함량 분석)

  • Beom, Seok-Hyun;Kwon, Hyun-Ji;Hyun, Jin-A;Kang, Eun-Bin;Park, Ha-Eun;Han, Dong-Geun;Kim, Hyun-Jeong;Choi, Eun-Young;An, Bong-Jeon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.47 no.4
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    • pp.333-340
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    • 2021
  • In this study, Rosa multiflora was sampled through extraction, concentration, and freezing. The antioxidant efficacy of a mixture of R. multiflora extract and ascorbic acid was compared with a single ascorbic acid. The purpose of this study was to analyze the antioxidant efficacy through the synergistic effect of R. multiflora extract and ascorbic acid. The experiment measured electron donating ability, ABTS+ radical scavenging, SOD-like activity, xanthine oxidase inhibition activity, reducing power, FRAP, polyphenolic content measurement, and flavnoid content measurement. As a result, the complex showed higher antioxidant activity than the control group (ascorbic acid) in the electron donating ability test and the xanthine oxidase inhibitory activity test. In the case of the flavonoid content experiment, it was confirmed that RMW+A (272.1 mg QE/g), RME+A (90.6 mg QE/g), and RMW+A (79.4 mg QE/g) at a concentration of 100 ㎍/mL had a higher flavonoid content than the control group (19.0 mg QE/g). Therefore, the extract and ascorbic acid complex exhibited a synergistic effect compared to the single use. Therefore, it is thought that this complex will contribute to product stabilization and skin aging inhibition when used in antioxidant cosmetics.

Evaluations on Antioxidant Effect of Water Extract from Graviola Leaves (그라비올라잎 열수추출물의 항산화 효능 평가)

  • Choi, Jong-Hwa;Ohk, Seung-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.6
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    • pp.129-135
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    • 2017
  • This study examined the antioxidant activity of the water extract from graviola leaves to develop a harmless and highly stable natural antioxidant. The total polyphenol content, total flavonoid content, DPPH radical scavenging activity, and MTT assay activity were measured. As a result, 62.3 g of the water extract from graviola leaves was obtained at $98^{\circ}C$ using 300 g of graviola leaf powder. The total polyphenol content was $291.97+2.39{\mu}g/mL$ and the total flavnoid content was $161{\pm}7.85{\mu}g/mL$ in a 1 mg/mL water extract from graviola leaves. The DPPH radical scavenging activity showed 51.6%, 67.8%, 79%, 82.4% and 83.9% at concentrations of 1, 2.5, 5, 10 and 15 mg/mL. This shows concentration-dependent scavenging activity and significant antioxidant activity. As a result of measuring the toxicity about HDF cells, a HDF cell survival rate of 100% was observed at a 150 mg /mL concentration, which was the same as that of the control group and a higher cell survival rate at a lower concentration. In conclusion, the graviola leaf extract can be developed as a material of food or cosmetics containing natural antioxidants.