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Classification method of chronic gastritis by modeling of pulse signal (맥파 모델링을 통한 만성위염 분류 기법)

  • Choi, Sang-Ho;Shin, Ki-Young;Shin, Jitae
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.5 no.3
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    • pp.144-151
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    • 2012
  • Chronic gastritis is the disease that is occuring in one in every 10 persons in Korea. In western medicine, endoscopy is needed to diagnose chronic gastritis, but it causes patients a pain and budget of expense. According to the TEM (Traditional Eastern Medicine), on the other hand, the 'Guan' position of the right wrist is related to a stomach. Thus we can diagnosis chronic gastritis by analyzing of pulse signal. However, pulse signal diagnosis is depended on oriental doctor's knowledge and experience. In this study, a systematic approach is proposed to analyze the computerized pulse signal. The pulse signals are firstly pre-processed, Gaussian model is adopted to fit the pulse signal, and then some related parameters are extracted from the model. Consequently, disease-sensitive parameters are selected by T-test and statistical difference. Finally, the selected parameters are entered into a Fuzzy C-Means (FCM) algorithm for classification. Classification results show that healthy persons and chronic gastritis patients are 95% and 87%, respectively.

FPGA Implementation of VME System Controller (VME 시스템 제어기의 FPGA 구현)

  • Bae, Sang-Hyun;Lee, Kang-Hyeon
    • The Transactions of the Korea Information Processing Society
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    • v.4 no.11
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    • pp.2914-2922
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    • 1997
  • For FA (factory automation) and ATE (automatic test equipment) in the industrial area, the standard bus needs to increase the system performance of multiprocessor environment. VME(versa module european package format) bus is appropriated to the standard bus but has features of small package and low board density. Beside, the density of board and semiconductor have grown to become significant issues that affect development time, project cost and field diagnostics. To fit this trend, in this paper, we composed Revision C.1 (IEEE std. P1014-1987) of the integrated environment for the main function such as arbitration, interrupt and interface between, VMEbus and several control modules Also the designed, VME system controller is implemented on FPGA that can be located even into slot 1. The control and function modules are coded with VHDL mid-fixed description method and then those operations are verified by simulation. As a result of experiment, we confirmed the most important that is the operation of Bus timer about Bus error signal should occur within $56{\mu}m$, and both control and function modules have the reciprocal operation correctly. Thus, the constructed VHDL library will be able to apply the system based VMEbus and ASIC design.

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Measuring Library User Satisfaction using the Public-service Customer Satisfaction Index (PCSI) (공공기관 고객만족지수(PCSI) 모형을 적용한 도서관 고객만족도 측정)

  • Kwon, Nahyun;Pyo, Soon Hee;Lee, Jungyeoun
    • Journal of the Korean Society for Library and Information Science
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    • v.52 no.1
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    • pp.313-340
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    • 2018
  • The purpose of this study was to design a PCSI model that can be applicable to measurement of library user satisfactions, which can be used in evaluating organizational performance. The National Assembly Library (NAL) was selected as a case to design a PCSI-based model and to test the model by conducting a self-administered survey of 341 internal and external library users. The model was validated to have a satisfactory model fit. Fitting the model, the study confirms that the service qualities of the NAL affect user satisfactions, which in turn affects organizational performances. The PCSI score of the library was 80.4, which can be used as a useful index that can compare the library's performance with other organizations in the similar public domain. Major contributions of this study are two-fold: the PCSI-based model proposed in this study provides a theoretical basis that assesses organizational performance of libraries via user satisfaction; and libraries can utilize the model as a management tool to assess the organizational performance from the user perspective.

Heavy metal adsorption of a novel membrane material derived from senescent leaves: Kinetics, equilibrium and thermodynamic studies

  • Zhang, Yu;Tang, Qiang;Chen, Su;Gu, Fan;Li, Zhenze
    • Membrane and Water Treatment
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    • v.9 no.2
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    • pp.95-104
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    • 2018
  • Copper pollution around the world has caused serious public health problems recently. The heavy metal adsorption on traditional membranes from wastewater is limited by material properties. Different adsorptive materials are embedded in the membrane matrix and act as the adsorbent for the heavy metal. The carbonized leaf powder has been proven as an effective adsorbent material in removing aqueous Cu(II) because of its relative high specific surface area and inherent beneficial groups such as amine, carboxyl and phosphate after carbonization process. Factors affecting the adsorption of Cu(II) include: adsorbent dosage, initial Cu(II) concentration, solution pH, temperature and duration. The kinetics data fit well with the pseudo-first order kinetics and the pseudo-second order kinetics model. The thermodynamic behavior reveals the endothermic and spontaneous nature of the adsorption. The adsorption isotherm curve fits Sips model well, and the adsorption capacity was determined at 61.77 mg/g. Based on D-R model, the adsorption was predominated by the form of physical adsorption under lower temperatures, while the increased temperature motivated the form of chemical adsorption such as ion-exchange reaction. According to the analysis towards the mechanism, the chemical adsorption process occurs mainly among amine, carbonate, phosphate and copper ions or other surface adsorption. This hypothesis is confirmed by FT-IR test and XRD spectra as well as the predicted parameters calculated based on D-R model.

Fatigue performance and life prediction methods research on steel tube-welded hollow spherical joint

  • Guo, Qi;Xing, Ying;Lei, Honggang;Jiao, Jingfeng;Chen, Qingwei
    • Steel and Composite Structures
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    • v.36 no.1
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    • pp.75-86
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    • 2020
  • The grid structures with welded hollow spherical joint (WHSJ) have gained increasing popularity for use in industrial buildings with suspended cranes, and usually welded with steel tube (ST). The fatigue performance of steel tube-welded hollow spherical joint (ST-WHSJ) is however not yet well characterized, and there is little research on fatigue life prediction methods of ST-WHSJ. In this study, based on previous fatigue tests, three series of specimen fatigue data with different design parameters and stress ratios were compared, and two fatigue failure modes were revealed: failure at the weld toe of the ST and the WHSJ respectively. Then, S-N curves of nominal stress were uniformed. Furthermore, a finite element model (FEM) was validated by static test, and was introduced to assess fatigue behavior with the hot spot stress method (HSSM) and the effective notch stress method (ENSM). Both methods could provide conservative predictions, and these two methods had similar results. However, ENSM, especially when using von Mises stress, had a better fit for the series with a non- positive stress ratio. After including the welding residual stress and mean stress, analyses with the local stress method (LSM) and the critical distance method (CDM, including point method and line method) were carried out. It could be seen that the point method of CDM led to more accurate predictions than LSM, and was recommended for series with positive stress ratios.

The history of high intensity rainfall estimation methods in New Zealand and the latest High Intensity Rainfall Design System (HIRDS.V3)

  • Horrell, Graeme;Pearson, Charles
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.16-16
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    • 2011
  • Statistics of extreme rainfall play a vital role in engineering practice from the perspective of mitigation and protection of infrastructure and human life from flooding. While flood frequency assessments, based on river flood flow data are preferred, the analysis of rainfall data is often more convenient due to the finer spatial nature of rainfall recording networks, often with longer records, and potentially more easily transferable from site to site. The rainfall frequency analysis as a design tool has developed over the years in New Zealand from Seelye's daily rainfall frequency maps in 1947 to Thompson's web based tool in 2010. This paper will present a history of the development of New Zealand rainfall frequency analysis methods, and the details of the latest method, so that comparisons may in future be made with the development of Korean methods. One of the main findings in the development of methods was new knowledge on the distribution of New Zealand rainfall extremes. The High Intensity Rainfall Design System (HIRDS.V3) method (Thompson, 2011) is based upon a regional rainfall frequency analysis with the following assumptions: $\bullet$ An "index flood" rainfall regional frequency method, using the median annual maximum rainfall as the indexing variable. $\bullet$ A regional dimensionless growth curve based on the Generalised Extreme Value (GEV), and using goodness of fit test for the GEV, Gumbel (EV1), and Generalised Logistic (GLO) distributions. $\bullet$ Mapping of median annual maximum rainfall and parameters of the regional growth curves, using thin-plate smoothing splines, a $2km\times2km$ grid, L moments statistics, 10 durations from 10 minutes to 72 hours, and a maximum Average Recurrence Interval of 100 years.

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Association of Thigh Muscle Mass with Insulin Resistance and Incident Type 2 Diabetes Mellitus in Japanese Americans

  • Han, Seung Jin;Boyko, Edward J.;Kim, Soo-Kyung;Fujimoto, Wilfred Y.;Kahn, Steven E.;Leonetti, Donna L.
    • Diabetes and Metabolism Journal
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    • v.42 no.6
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    • pp.488-495
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    • 2018
  • Background: Skeletal muscle plays a major role in glucose metabolism. We investigated the association between thigh muscle mass, insulin resistance, and incident type 2 diabetes mellitus (T2DM) risk. In addition, we examined the role of body mass index (BMI) as a potential effect modifier in this association. Methods: This prospective study included 399 Japanese Americans without diabetes (mean age 51.6 years) who at baseline had an estimation of thigh muscle mass by computed tomography and at baseline and after 10 years of follow-up a 75-g oral glucose tolerance test and determination of homeostasis model assessment of insulin resistance (HOMA-IR). We fit regression models to examine the association between thigh muscle area and incidence of T2DM and change in HOMA-IR, both measured over 10 years. Results: Thigh muscle area was inversely associated with future HOMA-IR after adjustment for age, sex, BMI, HOMA-IR, fasting plasma glucose, total abdominal fat area, and thigh subcutaneous fat area at baseline (P=0.033). The 10-year cumulative incidence of T2DM was 22.1%. A statistically significant interaction between thigh muscle area and BMI was observed, i.e., greater thigh muscle area was associated with lower risk of incident T2DM for subjects at lower levels of BMI, but this association diminished at higher BMI levels. Conclusion: Thigh muscle mass area was inversely associated with future insulin resistance. Greater thigh muscle area predicts a lower risk of incident T2DM for leaner Japanese Americans.

The Mediating Effect of Bullying on the Associations Between Children's overweight and Obesity Problem and Mental Health Problems (아동의 과체중·비만과 정신건강문제의 관계 -집단따돌림의 매개효과-)

  • Kim, Jin-Hee
    • Journal of the Korean Society of Child Welfare
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    • no.40
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    • pp.201-228
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    • 2012
  • The purpose of this research was to investigate the mediation effect of bullying on the associations between children's overweight and obesity problem and mental health problems. Data from a subsample of 2,306 adolescents, who participated in the "child-youth synthesize survey" was utilized. The measurement and structural models were estimated using structural equation modeling. Partial and full mediation models were compared, and X2 difference test was conducted between the two models. The study results show that children's overweight and obesity problem have a direct effect on mental health problems. In addition, bullying was found to mediate the association between children's overweight and obesity problem and mental health problems. The analytic results confirmed that the model fit for the full mediation model was better than the partial mediation model when examining the mediating effect of bullying on the relations between children's overweight and obesity problem and mental health problems. Efforts to prevent mental health problems may require interventions for children's with overweight and obesity problems as well as inventions for reducing bullying in general.

Modified Pharmacokinetic/Pharmacodynamic model for electrically activated silver-titanium implant system

  • Tan, Zhuo;Orndorff, Paul E.;Shirwaiker, Rohan A.
    • Biomaterials and Biomechanics in Bioengineering
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    • v.2 no.3
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    • pp.127-141
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    • 2015
  • Silver-based systems activated by low intensity direct current continue to be investigated as an alternative antimicrobial for infection prophylaxis and treatment. However there has been limited research on the quantitative characterization of the antimicrobial efficacy of such systems. The objective of this study was to develop a semi-mechanistic pharmacokinetic/pharmacodynamic (PK/PD) model providing the quantitative relationship between the critical system parameters and the degree of antimicrobial efficacy. First, time-kill curves were experimentally established for a strain of Staphylococcus aureus in a nutrientrich fluid environment over 48 hours. Based on these curves, a modified PK/PD model was developed with two components: a growing silver-susceptible bacterial population and a depreciating bactericidal process. The test of goodness-of-fit showed that the model was robust and had good predictability ($R^2>0.7$). The model demonstrated that the current intensity was positively correlated to the initial killing rate and the bactericidal fatigue rate of the system while the anode surface area was negatively correlated to the fatigue rate. The model also allowed the determination of the effective range of these two parameters within which the system has significant antimicrobial efficacy. In conclusion, the modified PK/PD model successfully described bacterial growth and killing kinetics when the bacteria were exposed to the electrically activated silver-titanium implant system. This modeling approach as well as the model itself can also potentially contribute to the development of optimal design strategies for other similar antimicrobial systems.

A Systematic Analysis on Default Risk Based on Delinquency Probability

  • Kim, Gyoung Sun;Shin, Seung Woo
    • Korea Real Estate Review
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    • v.28 no.3
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    • pp.21-35
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    • 2018
  • The recent performance of residential mortgages demonstrated how default risk operated separately from prepayment risk. In this study, we investigated the determinants of the borrowers' decisions pertaining to early termination through default from the mortgage performance data released by Freddie Mac, involving securitized mortgage loans from January 2011 to September 2013. We estimated a Cox-type, proportional hazard model with a single risk on fundamental factors associated with default options for individual mortgages. We proposed a mortgage default model that included two specifications of delinquency: one using a delinquency binary variable, while the other using a delinquency probability. We also compared the results obtained from two specifications with respect to goodness-of-fit proposed in the spirit of Vuong (1989) in both overlapping and nested models' cases. We found that a model with our proposed delinquency probability variable showed a statistically significant advantage compared to a benchmark model with delinquency dummy variables. We performed a default prediction power test based on the method proposed in Shumway (2001), and found a much stronger performance from the proposed model.