• 대한소아치과학회지
• /
• 제25권2호
• /
• pp.458-466
• /
• 1998

Non-odontogenic tumors can be classified as malignant or benign. Most oral tumors in children are benign. In the Belfast series only 7.5 percent of soft tissue tumors were malignant and Bhaskar(l963) found only 9 percent of 293 oral tumors of all kinds to be malignant. Benign tumors may be classified as epithelial and mesenchymal. The most common tumor of surface epithelium is the squamous papilloma. These are easily recognized clinically as cauliflower-like lesions. Fibrous lesions are very common in children's mouths. Many of these are not true neoplasms but are related to fibrous hyperplasia. Another common oral tumor in children is angiomatous tumors. Hemangioma occurred more frequently than lymphangioma. Cystic hygroma, a cystic subtype of lymphangioma, is a developmental tumor of lymphatic origin. It is a considered to be a relatively rare lesion. About 50 percent of cystic hygroma are present at birth, and most of the remaining 50 percent appear in the early years of life during the period of active lymphatic growth. The preferred treatment for these lesions, except for hemangioma, is complete surgical excision. With proper surgical techniques, recurrence is not expected.

• Restorative Dentistry and Endodontics
• /
• 제42권2호
• /
• pp.111-117
• /
• 2017

Objectives: Periapical lesions, including periapical cyst (PC), periapical granuloma (PG), and periapical abscess (PA), are frequently affected by chemical/physical damage during root canal treatment or severe bacterial infection, and thus, the differential diagnosis of periapical lesions may be difficult due to the presence of severe inflammatory reaction. The aim of this study was to make differential diagnosis among PC, PG, and PA under polarizing microscope. Materials and Methods: The collagen birefringence patterns of 319 cases of PC (n = 122), PG (n = 158), and PA (n = 39) obtained using a polarizing microscope were compared. In addition, 6 cases of periodontal fibroma (PF) were used as positive controls. Results: Collagen birefringence was condensed with a thick, linear band-like pattern in PC, but was short and irregularly scattered in PG, and scarce or absent in PA. PF showed intense collagen birefringence with a short, palisading pattern but no continuous band-like pattern. The linear band-like birefringence in PC was ascribed to pre-existing expansile tensile stress of the cyst wall. Conclusions: In this study all PCs (n = 122) were distinguishable from PGs and PAs by their characteristic birefringence, despite the absence of lining epithelium (n = 20). Therefore, the authors suggest that the presence of linear band-like collagen birefringence of the cyst wall aids the diagnostic differentiation of PC from PG and PA.

• Archives of Plastic Surgery
• /
• 제49권3호
• /
• pp.413-417
• /
• 2022

The authors present a unique case of osteonecrosis of a cortical half of a fibula free flap that has not been reported in the literature yet. This complication was associated with the impairment of the vascularization of periosteum in the cortical half of fibula that was fixated with a nonlocking reconstructive 2.0-mm plate and screws but other factors could have been involved. The patient was submitted to excision of a cemento-ossifying fibroma that resulted in a left hemimaxilectomy mesoinfrastructure defect classified as the Cordeiro type 2B. The 42-year-old female patient was submitted to reconstruction with an osteomusculocutaneous fibula free flap plus a segment of fibula graft. The two bone segments of the free flap used to reconstruct the anterior and left alveolar crest were fixated with a reconstructive 2.0-mm plate of matrixMANDIBLE system. The only reported complication was an oronasal fistula that healed with conservative treatment and the referred osteonecrosis of the external cortical half of the fibula free flap with plate exposure at 2.5 years postoperatively. Surgical excision of the osteonecrosed cortical half of the fibula with the plate and screws was performed, while the other cortical underwent bone union as corroborated by computed tomography scans.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제47권2호
• /
• pp.112-119
• /
• 2021

Objectives: Myxomatous odontogenic tumors (MOTs) are the third most common odontogenic tumors in the oral and maxillofacial region. Due to its slow-growing, but locally invasive nature, the tumor is usually detected by accident or only when it becomes a large mass, which causes facial deformity. Materials and Methods: Current study reports three unusual cases of MOT including huge myxoma involve the mandible in middle-aged man, MOT with ossifying fibroma pattern in mandible, and MOT in maxilla of young female patient. The diagnosis and treatment strategy of MOTs was also summarized and updated. Results: In reported three cases of patients with large MOTs, surgical treatment was indicated with fibular free flap reconstruction in the mandible and plate reconstruction in the maxilla. The tumors were successfully treated with radical resection and did not show signs of recurrence during the follow-up period. Conclusion: Surgical treatment indication depends on size, the position of the lesion, patient systemic condition and surgeon individual experience. In the case of a large tumor, radical resection and reconstruction is the standard surgical strategy. The conservative surgical treatment including enucleation with wide curettage is still under controversy. The recurrence rate for MOTs is significantly high, up to 30%, therefore long-term follow-up is essential.

• 한국임상수의학회지
• /
• 제24권4호
• /
• pp.542-549
• /
• 2007

During a designated period(Jan. 2003$\sim$Jun. 2006), a total of 2,051 biopsy and necropsy cases submitted to Veterinary Medical Teaching Hospital of Seoul National University and local practitioners were diagnosed as canine tumors based on microscopic evaluation in the Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University. Four hundred and twenty of 2,051 tumor specimens excluding mammary(883, 43.1%) and cutaneous(748, 36.5%) tumors were included in this retrospective study. They were composed of genital tumors(189, 45.0%) followed by alimentary(113, 26.9%), hematopoietic(52, 12.4%), urinary(20, 4.8%), bone & joint(15, 3.6%), ocular & otic(9, 2.1%), respiratory(6, 1.4%), endocrine(6, 1.4%), and miscellaneous(10, 2.4%). Particular top ten tumor most frequently diagnosed were seminoma(48, 11.4%) followed by fibrous epulis(38, 9.0%), lymphoma(38, 9.0%), leiomyoma(33, 7.9%), fibroma(26, 6.2%), ovarian cyst(19, 4.5%), melanoma(15, 3.6%), papilloma(14, 3.3%), cystic endometrial hyperplasia(13, 3.1%), granulosa cell tumor(13, 3.1%) in descending order comprising 257(61.2%). The affected age of the animals with ten frequent tumors ranged from 3 months to 17 years old with a mean of 9.2 years old(n=218). There were no significant sex prevalence except female leiomyoma. The top seven anatomical sites of tumors inclusive were gingiva(62, 14.8%), testis(61, 14.5%), ovary(48, 11.4%), vagina(40, 9.5%), uterus(36, 8.6%), lymph node(30, 7.1%), and spleen(21, 5.0%).

• 대한골관절종양학회지
• /
• 제6권2호
• /
• pp.69-76
• /
• 2000

목적 : 족부 및 족관절에 발생하는 종양은 다른 부위에 비해 그 발생 빈도가 낮으며, 특히 악성 종양은 매우 드물고 양성 종양으로 간과되는 경우도 있어 족부 및 족관절에 발생한 종양의 임상 양상에 대해 알아보고자 하였다. 대상 및 방법 : 1989년부터 1998년까지 10년 동안 족부 종양으로 진단받은 72명을 대상으로 조사를 시행하였다. 결과 : 남자가 40예, 여자가 32예였다. 양성 종양이 53예(74%)로, 연부 조직 종양이 30예, 골 종양이 23예였다. 악성 종양은 19예(26%)였으며, 연부조직 종양이 17예, 원발성 골종양이 1예, 전이성 골종양이 1예였다. 양성 종양은 연부 조직에서는 섬유종이, 골종양에서는 골연골종이 가장 많았다. 악성 종양은 악성 흑색종이 7예로 가장 많았다. 호발 부위는 양성종양의 경우 족지부, 악성 종양의 경우 발 뒤꿈치 부위였다. 악성 종양 19예 중 국소 재발은 3예, 원격 전이는 8예에서 발생하였다. 결론 : 악성 종양이 26%였으며 원격 전이가 42%로 높았다. 따라서, 족부 종양의 경우 악성의 가능성을 염두에 두고, 치료 시에 병리학적인 확진이 필수적이라 하겠다.

• 대한골관절종양학회지
• /
• 제11권2호
• /
• pp.111-117
• /
• 2005

목적: 15세 이하의 소아에서 골종양에 2차적으로 발생한 대퇴골의 병적 골절의 치료 결과에 대해 알아보고자 하였다. 대상 및 방법: 1995년 1월부터 2004년 6월까지 골종양에 2차적으로 발생한 대퇴골의 병적 골절로 치료받았던 환자 중 1년 이상 추시가 가능하였던 18명, 20예를 대상으로 하였다. 평균 연령은 10.2세였고 평균 추시 기간은 42.5개월이었다. 결과: 골절 부위는 대퇴 근위부 14예, 간부 3예, 원위부 3예였으며, 원인 골종양은 섬유성 이형성증 9예, 단순 골낭종 4예, 동맥류성 골낭종 4예, 비골화성 섬유종 2예, 호산구성 육아종 1예였다. 치료 방법으로 골절에 대해서는 11예에서 석고고정을 이용한 보존적 치료를, 8예에 대해서는 내고정을 1예에서는 외고정을 시행하였다. 원발 종양에 대해서는 관찰만 시행한 경우가 11예, 소파술 및 골이식이 8예, 절제술이 1예에서 시행되었다. 다발성 섬유성 이형성증에서 모든 예에서 변형이 발생하여 변형 교정술 및 골수정 내고정술로 더 이상의 변형이나 재골절을 예방할 수 있었다. 결론: 골종양에 2차적으로 발생한 소아 대퇴골의 병적 골절은 그 치료가 어려우나 원발 골종양의 종류 및 그 특성에 따른 적절한 치료 방법을 선택하면 우수한 결과를 얻을 수 있을 것으로 생각된다.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제22권2호
• /
• pp.217-232
• /
• 2000

The author studied on the 128 cases of benign odontogenic tumors which had been diagnosed with biopsy during the period of Jan. 1989 to Dec. 1998 at the Kyungpook National University Hospital, Yeungnam University Medical Center, Keimyung University Dongsan Medical Center, and Taegu Catholic Medical Center. This study contained the clinicostatistical analysis of the frequency in relation to sex, age, locations, chief complaints, duration, radiographic findings, recurrence, teeth, and treatment methods. The results were as follow : 1. Of a total of 128 benign odontogenic tumors, ameloblastomas(57 cases; 44.5%) and odontomas (44 cases ; 34.4%) mostly occupied. The other types of lesions were 8 calcifying odontogenic cysts, 7 benign cementoblastomas, 4 myxomas, 3 adenomatoid odontogenic tumors, 2 calcifying epithelial odontogenic tumors, 2 ameloblastic fibro-odontomas, and 1 odontogenic fibroma. 2. In age and sex distribution, benign odontogenic tumors occured slightly more often in males(53.9%) than females(46.1%) and the majority of cases(79.7%) were found during 2nd, 3rd, and 4th decade. 3. There was a predilection for mandibular lesions(mandible-maxilla ratio, 2.6 : 1). 4. The most common chief complaint was swelling(29.7%) and in respect to duration, the cases less than 1 year(50.0%) mainly appeared. 5. There were 7 cases(13.0%) of recurrence on ameloblastoma and there was no recurrence in the others. 6. In Ameloblastoma It commonly occured during 3rd and 4th decade(59.6%) and mean age was 30.2 years. The majority of cases were occurred in mandible(96.5%) , especially mandibular molar and angle area(71.9%). The most common chief complaint was swelling(47.4%) and in respect to duration, the cases less than 1 year(52.6%) mainly appeared. In relation to teeth, there were resorption of root(52.6%), displacement of teeth(31.6%), and in relation to impacted teeth(43.9%). There was higher recurrence rate in the cases by conservative treatment(14.7%) than radical treatment(10.0%). As regards radiographic findings, conservative treatments were prevalent in the cases of unilocular type(85.7%) as compared with multilocular type(48.5%). and there was higherrecurrence rate in the cases of multilocular type(18.2%) than unilocular type(4.8%). As regards the type of treatment in relation to age, conservative treatments were prevalent in patients younger than 20 years of age. 7. In Odontomas It commonly occured during 2nd decade(50.0%) and in maxillary anterior teeth(40.9%). The most common chief complaint was delayed retention and permanent impaction of teeth(72.7%), and most frequently associated with impacted teeth(79.5%).

• Tuberculosis and Respiratory Diseases
• /
• 제51권1호
• /
• pp.65-69
• /
• 2001

폐암의 치은에의 전이는 매우 드물게 발생되는 질환으로 아직 국내보고는 없었다. 흉부 전산화단층촬영 및 조직검사를 통하여 치은으로 전이된 소세포 폐암으로 진단되어 항암화학요법과 방사선 치료를 받았으나 1년 후 사망한 증례를 경험하였기에 보고하는 바이다.

• 대한관절경학회지
• /
• 제7권1호
• /
• pp.70-75
• /
• 2003

목적 : 슬관절주위의 낭종유사 병변은 매우 드물고, 보고된 문헌이 거의없다. 이 논문의 목적은 드물게 보고되는 슬관절주위 낭종유사 병변의 관절경적인 절제제거술의 효용성을 알아보고자 함이다. 대상 및 방법 : 슬관절주위에서 발견된 14예의 낭종유사 병변을 대상으로 하였으며 3예의 슬개하 지방체의 결절종, 1예의 관절내 거대세포종은 거의 보고된 적이 없으며 1예의 관절낭주위 상피양 낭종과 1예의 관절내 섬유종은 전 세계적으로 보고된 적이 없다. 슬관절주위 낭종유사 병변의 진단은 자기공명영상을 이용하였고 병리조직검사에 의하여 확진되었다. 남자는 9예였고 여자는 5예였으며 평균나이는 24($11\~43$세) 였다. 최종 12개월 추시되었고 평균 추시기간은 45(12개월$\~$8년)개월이었다. 결과 : 모든 환자는 관절경을 이용한 절제제거술을 시행하였고 최종추시에서 초음파검사 및 자기공명영상 촬영을 실시하여 재발여부를 확인하였으며 최종추시 Lysholm 슬관절지수는 98.9점 $(95\~100)$이었고 최종추시시 4례에서 이학적검사상 경도의 이상소견을 보였으나 모두 만족하였다. 전례에서 우수의 결과를 얻었고 재발은 없었다. 결론 : 슬관절주위 낭종유사 병변의 관절경적인 절제제거술은 우수한 방법이고 이후 오랜기간의 추시가 필요하다.