• Journal of Korean Medical classics
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• v.25 no.3
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• pp.117-126
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• 2012

Objective : I would like to determine the main factors, in other words, the subjects that are responsible for febrile paroxysm and how they interact at the time of onset, based on the "Discourse on Hak(瘧)" chapter of "Huangdi Neijing(黃帝內經)". Methods : First, the pathological mechanism of the paroxysm was examined as described in the text. Then the subjects in question were analyzed based on the contents of the text. Result : 1. Febrile paroxysm happens when the three factors coincide at the Fengfu(風府). The three elements are as follows: first defense qi(衛氣), second latent qi(伏邪) and third, external pathogen(新邪). 2. Fengfu(風府) is not a specific point, but a region which external pathogen(新邪) passes through during which the defense qi is deficient. Conclusion : Febrile paroxysm is not caused by either an internal pathogen or an external pathogen, but the interaction between the three elements of the internal and external pathogens and the condition of defense qi. Moreover, the site, Fengfu(風府), which the disease is manifested is not a specific point but a more general region where the pathogenic qi has invaded while defense qi has weakened.

• Journal of Pharmacopuncture
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• v.16 no.4
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• pp.30-35
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• 2013

Objectives: This study was designed to investigate the effects of Calculus Bovis-Fel Uris-Moschus pharmacopuncture (BUM) on the regional cerebral blood flow (rCBF) and the mean arterial blood pressure (MABP) in normal and cerebral ischemic rats and to investigate a possible pathway involved in the effects of BUM. Methods: The changes in the rCBF and the MABP following BUM into Fengfu (GV16) were determined by using a laser-Doppler flow meter and a pressure transducer, respectively. Results: BUM significantly increased the rCBF and decreased the MABP in normal rats in a dose-dependent manner. The effect on the rCBF was significantly inhibited by pretreatment with methylene blue (0.01 mg/kg, intraperitoneal), an inhibitor of guanylate cyclase, but was not affected by pretreatment with indomethacin (1 mg/kg, intraperitoneal), an inhibitor of cyclooxygenase. The BUM-induced decrease of the MABP was changed neither by methylene blue nor by indomethacin pretreatment. In the cerebral ischemic rats, the rCBF was stably increased upon cerebral reperfusion in the BUM group in contrast to the rapid and marked increase in the control group. Conclusion: This study demonstrated that BUM into Fengbu (GV16) increased the rCBF in a dose-dependent manner in the normal state; furthermore, it improved the stability of the rCBF in the ischemic state upon reperfusion. Also, the effects of BUM on the rCBF were attenuated by inhibition of guanylate cyclase, suggesting that the effects involved the guanylate cyclase pathway.

• The Journal of Korean Medicine
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• v.16 no.1 s.29
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• pp.468-474
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• 1995

After bibliographic study on function of the brain(腦, nao) on the basis of zangxiang theory(藏象論的), the theory of visceral activities), the following conclusions were obtained: 1. Brain is the organ conglomerated with marrow(隨, sui) between Baihui(百會) and Fengfu(風府) 2. Brain has different function and names according to the parts. 3. Brain is on anatomical view the extraordinary organ(奇恒之府, qiheng zhi fu) and stores clarified air(氣, qi) of fresh air. 4. Brain is the places where the viral essence (精, jeong) of five viscera is activated. 5. Brain is the places where the vital essence congeries into the mind(神, shen) Yang form of the essence. 6. The mind converted from the brain emerges in the whole body the sensory organs and carries vital function. 7. Brain reservoirs the mind, while the heart(心, xm) is thought to make judgement inroyght the speculation on the outward stimulus of matter and give orders to the mind in the chest.