• 한국전문물리치료학회지
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• 제19권1호
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• pp.56-65
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• 2012

This study examines the effects of a rehabilitation program on quality of life (QOL), cardiopulmonary function and fatigue during radiotherapy for breast cancer patients. The program includes aerobic exercise, stretching and strengthening exercises. Sixty-five women participated in this study and they were asked to perform supervised exercises that last for 60 minutes five times a week for six weeks. The European organization for research and treatment of cancer-cancer (EORTC QLQ-C30) and the breast (EORTC QLQ-BR23), predicted maximal volume of oxygen consumption ($VO_{2max}$) and fatigue severity scale (FSS) were assessed before and after the rehabilitation program. The 60-minute program consisted of a 10-minute warm-up, 30-minute of aerobic exercises, and 15-minute of strengthening exercises, followed by a five-minute cool-down. Heart rates were monitored throughout the exercise class to ensure that patients were exercising at the target heart rate of 40~75% of the age-adjusted heart rate maximum. There were statistically significant differences in the changes of physical function and cancer related symptoms in the EORTC QLQ-C30 and EORTC QLQ-BR23 (p<.05). There was a statistically significant improvement in the predicted $VO_{2max}$ (p<.05), although there were no significant differences in the FSS (p>.05). The results of our study suggest that a supervised rehabilitation program may benefit the physical aspects and QOL of patients receiving radiotherapy for breast cancer.

• 대한중풍순환신경학회지
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• 제20권1호
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• pp.25-32
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• 2019

■ Objectives In this case report, we address a case of a 83-year-old female patient diagnosed with suspicious autoimmune hepatitis. ■ Methods A patient was treated with herbal medication, Injinoryung-san gagam. We evaluated the improvements of symptoms by AST, ALT, GGT, ALP and total score of Fatigue Severity Scale(FSS). ■ Results After 4 weeks of taking Injinoryung-san gagam, there were decrease in abnormal liver enzyme levels with improvement of the patient's fatigue. ■ Conclusion This study suggested that Injinoryung-san gagam might be effective in autoimmune hepatitis patient's liver enzyme levels and fatigue recovery.

• 정신신체의학
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• 제22권1호
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• pp.3-12
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• 2014

연구 목적 피로의 심각도에 영향을 준다고 생각되는 인구 사회학적 변인들과 스트레스 지각 정도, 우울 감의 상관 관계를 파악하고, 이를 향후 임상 환자군, 일차 진료 환자 군에서의 피로 증상의 평가 및 치료 전략에 대한 기초 자료를 제공하고자 한다. 방 법 621명의 남, 여 공무원 집단을 대상으로 반 구조화된 설문 자료를 이용하여, 연구 참여자의 기본적인 인구 사회학적 변인과 생활 습관에 대한 조사와 함께, 피로 심각도 척도(FSS), 개인의 지각된 스트레스 척도(PSS), 한국형 BEPSI 검사(BEPSI-K), 벡의 우울 감 척도(BDI), 스트레스 대처 방식(Stress coping skill Questionnaire)을 기입하도록 하였고, 이를 이용하여 단면적 연구를 시행하였다. 결과 피로, 스트레스 지각 정도, 우울 감은 모두 남성보다 여성에서 평균값이 유의하게 높게 관찰되었다. 피로의 심각도는 스트레스 지각 정도, 우울 감과 양의 상관관계를 보였다. 피로 심각도는 어떠한 대처 방식을 사용하느냐에 따라 다르게 관찰되었는데, 적극적인 대처 방식을 더 많이 사용하는 사람들이 느끼는 피로와 우울 감이 상대적으로 낮았다. 적극적 대처 방식 중에서도 문제 중심적인 대처 방식을 사용하는 군에서 피로의 심각도와 우울 감이 유의한 음의 상관관계를 보였다. 반면에 소극적 대처 방식을 더 많이 사용하는 집단에서 피로의 심각도는 스트레스 지각 정도, 우울 감 모두에서 양의 상관관계를 보였다. 높은 피로를 호소하는 그룹(FSS>3.22)에서 지각된 스트레스, 우울 감이 모두 유의하게 높게 나타났고, 고 피로 군은 저 피로 군에 비해서 문제 중심적 대처 방식을 덜 사용하는 것으로 나타났다. 로지스틱 회귀 분석 결과, 스트레스 지각 정도와 우울 감은 피로의 발생과 증상의 심각 도에 위험 요인으로 작용하며, 운동을 규칙적으로 하는 것은 운동을 하지 않는 것에 비해 피로를 경감시키는 요인으로 밝혀졌다. 결론 지각하는 스트레스가 높을 수록, 우울 감을 많이 느낄수록 피로가 높아지는 것을 확인하였고, 운동을 하지 않는 군에서 운동을 하는 군에 비해 피로를 더 많이 느끼는 것을 확인하였다. 이번 연구에서는 건강한 사람들을 대상으로 주관적인 피로감을 측정하고 피로에 영향을 주는 요인들을 확인하였기 때문에, 이 결과가 추후 일반 건강 군의 피로에 대한 치료적 개입뿐 아니라, 피로 심각도에 영향을 주는 요인인 스트레스와 우울 감, 그리고 이들로 인하여 발생 가능한 여러 가지 정신과적 질환에의 개입과 치료 전략 수립 시에 기초적인 자료가 될 수 있을 것으로 생각된다.

• 종양간호연구
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• 제9권2호
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• pp.77-85
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• 2009

Purpose: The purpose of this study was to identify symptom cluster experienced by patients with advanced non-small cell lung cancer (NSCLC) on gefitinib treatment. In addition, this study assessed the patterns in severity of the symptom cluster and differences in quality of life (QOL) and function among subgroups by the severity of symptom cluster. Methods: This study was conducted as a secondary analysis of symptoms of 72 patients from a mother study. Factor analysis was used to identify symptom clusters measured with EORTC QLQ-C30 and LC13 symptom related items. Results: Three symptom clusters were identified: cluster 1 was comprised of fatigue, anorexia and dysphagia; cluster 2 of dyspnea, cough and insomnia; and cluster 3 of pain, constipation and nausea/vomiting. These three symptom clusters were improved one week after gefitinib administration. The group with more severe symptom clusters showed significantly lower QOL and function than the group with less severe symptom clusters. Conclusion: Since symptom clusters experienced by the patients with advanced NSCLC influenced on the QOL and function, it is important for nurses to understand and observe their symptom clusters. In addition, there is an necessity to develop nursing interventions to effectively care patients with the symptom clusters.

• 성인간호학회지
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• 제17권2호
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• pp.248-258
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• 2005

Purpose: The purpose of this study is to examine the factors influencing symptom experience in patients with liver cirrhosis(LC). Method: A descriptive correlational study design was used. A convenience sample of 129 subjects was recruited from the gastroenterology department at two university hospitals in Seoul, Korea. Symptom experience in LC was measured with the instrument developed by the researcher based on Theory of Unpleasant Symptoms(Lenz et al, 1995) and the Child-Pugh Score, the Korean version of Profile of Mood States, and the Family Support Questionnaire were used to identify the factors influencing symptom experience. Results: The mean score of symptom experience was relatively low(M=41.67, SD= 24.71). Among individual symptoms, fatigue had the highest score in all dimensions. Fatigue, abdominal distension and/or peripheral edema, muscle cramps, dry mouth, and change in appearance were explored as symptoms needing management. In the regression analysis, symptom experience was found to be influenced significantly by anxiety/depression($R^2=.418$, p=.000) and the severity of LC(Child-Pugh Score)($R^2=.125$, p=.000). These variables explained 54.3% of the variance in symptom experience(F=63.607. p=.000). Conclusion: It suggests that nurses need to take into consideration psychological factor as well as physiological factor in symptom management for patients with LC.

• 한방안이비인후피부과학회지
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• 제10권1호
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• pp.340-348
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• 1997

The glaucoma, cataract and causing-blindness-diseases have high clinical importance by their severity of the symptoms and possibility of causing visual loss. Glaucoma is caused by an increase in the intraocular pressure, if severe enough, can cause field loss and eventually complete blindness. In cataract, the general clarity of vision is impaired due to a loss of transparency of the chrystalline lens of the eye. The causing-blindness-diseases can be divided to PokMaeng which cause sudden blindness and ChungMaeng, in which visual acuity is losed gradually. In glaucoma, cataract and causing-blindness-diseases, the visual acuity is affected and the patient may complain blurriness, fatigue of eye, visual field loss deficiency or scintillant feeling, vitreous floaters. In this study, 32 patients who have cataract, glaucoma or other causing-blindness-diseases was treated with oriental medicine or acupuncture from July, l996 to May. 1997, and was followed up by their symptoms and visual acuity. 1. In glaucoma patients, intraocular pressure decreased significantry and the symptoms improved positively. 2. In cataract patients, there was no improvement of visual acuity but $40\%$ of patients found their symptoms improved. 3. In causing-blindness-diseases, $57\%$ of patients reported improvement of their symptoms such as blurriness or fatigue of eye. 4. Through oriental medical treatment, the symptoms of glaucoma, cataract and causing-blindness-diseases can be treated effectively. Therefore oriental management seems to be possible to cure glaucoma, cataract and causing-blindness-diseases.

• 대한한의학회지
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• 제26권2호
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• pp.25-31
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• 2005

Objectives: This study was designed to assess traditional Korean medical therapy for urticaria and establish a clinical assessment guideline. Methods: Duration of symptoms, personal and family history of allergic diseases, serum IgE level, suspected causes and Provocation factors were investigated in 56 patients. Frequency of wheals, duration of wheals, number of wheals, itch severity and antihistamine counts on a 6-point (0-5) scale were assessed in 34 patients. The change of total scores and each criterion between baseline and follow up were analyzed using paired t-test (p<0.05). Results: 1. Acute urticaria within 6 weeks was $26.8\%$ and chronic urticaria over 6 weeks was $73.2\%$. The mean duration of symptoms was $19.2\pm38.8$ months. 2. $57.1\%$ of patients had a personal history of allergic diseases and $50\%$had a family history. $29.1\%$ had over 200 IU/mL serum IgE level. 3. The suspected causes were none $(39.3\%)$, foods $(32.1\%)$, drugs $(12.5\%)$, contact $(5.4\%)$ and maternity$(5.4\%)$. 4. The suspected provocation factors were foods $(41.1\%)$, none $(26.8\%)$, fatigue $(12.5\%)$, heat and sweating $(12.5\%)$, pressure $(10,7\%)$ and stress $(7.1\%)$. 5. The total scores between baseline and follow up of 34 patients were lowered from $15.38^{\circ}\;{\ae}3.75\;to\;8.82^{\circ}\;{\ae}5.21$, which was significant statistically (p=0.000). 6. Itch severity, frequency of wheals and number of wheals were the most significantly lowered of all criteria. Conclusions: Traditional Korean medical therapy was proven to be effective for urticaria, while itch severity, frequency of wheals and number of wheals should be assessed clinically with greater priority.

• 대한암한의학회지
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• 제18권1호
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• pp.23-31
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• 2013

Objectives : The purpose of this case study is to demonstrate the effectiveness of Traditional Korean Medicine as an adjunctive management for breast cancer treatment. Methods : A 56 year-old female patient diagnosed with stage IA(pT1cN0M0) of breast cancer was admitted our hospital. The patient had surgical resection followed by radiation therapy, and conducted adjuvant therapy with aromatase inhibitor. The patient's chief complaints were dry cough, thirst and fatigue, all of which were caused by radiation therapy. Traditional Korean herbal medicine was prescribed for symptom management. The patient's subjective symptoms such as cough, thirst and fatigue were evaluated by NRS. Results : Fatigue was significantly improved within a week. The severity of dry cough and thirst also was decreased after a few courses of herbal medicine treatment. Conclusion : This case study suggests that Tradition Korean Medicine would be beneficial for the patients who are suffering from adverse effects of the standard treatment of cancer.

• 디지털융복합연구
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• 제18권11호
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• pp.559-569
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• 2020

본 연구는 요양병원 요양보호사의 작업환경, 심리적 업무요구, 피로도, 근골격계 증상의 관계를 파악하고 근골격계 증상에 미치는 영향요인을 규명하기 위해 시도되었다. 연구방법은 S시에 소재한 3곳의 요양병원에 근무하는 요양보호사 128명을 대상으로 2020년 4~5월까지 설문 조사하였다. 연구결과 요양병원 요양보호사의 근골격계 증상은 어깨, 손/손목/손가락, 허리 세 부분에 대한 증상발생빈도, 증상지속기간, 통증의 강도를 합한 값으로 42점 만점에 평균 11.41±9.50점으로 나타났다. 요양병원 요양보호사의 근골격계 증상에 미치는 영향요인을 규명하기 위해 회귀분석을 실시한 결과 근무병동(β=.18, p=.034)과 심리적 업무요구(β=.21, p=.013), 피로도(β=.25, p=.003)가 근골격계 증상에 유의한 영향을 미치는 것으로 나타났으며, 이들 3개 변수는 근골격계 증상에 대하여 21.6%의 설명력을 보였다(F=6.87, p<.001). 본 연구결과를 바탕으로 요양병원 요양보호사들의 근골격계 증상을 감소시키기 위해서는 담당하는 환자의 중증도를 고려하여 심리적 업무요구와 피로도를 줄일 수 있는 중재프로그램 개발 및 적용이 필요하다.

• 수면정신생리
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• 제7권2호
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• pp.79-83
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• 2000

Sleep disturbances are frequently associated with neurological disorders. Sleep disorders interfere with rehabilitation of patients with neurological disorders such as stroke and may increase the severity of their symptoms and recurrence rate of stroke. The treatment of sleep apnea syndrome is particularly important in managing patients with cerebral infarction of whom 50-80% have moderate to severe sleep apnea. Sleep apnea produces not only poor quality sleep but also excessive daytime sleepiness, fatigue and lack of energy. Sleep problems frequently found in patients with dementia are sleep-wake cycle abnormality, fragmentation of sleep, nocturnal insomnia, decreased slow wave sleep and REM sleep, and sleep disordered breathing. The management of sleep disturbances is very important for controlling symptoms such as nocturnal wandering and sundowning syndrome in patients with dementia. Parkinson's disease and epilepsy are other neurological disorders that may have sleep disturbances.