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Review of Korean Medicine Treatments for Purpura and Vasculitis in Korean Journals (혈관염 및 자반증의 한의학적 치료에 대한 국내 임상 논문 분석)

  • Kang, Dong-Won;Park, Jung-Gun;Han, Chang-Yi;Kim, Kyu-Seok;Kim, Yoon-Bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.3
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    • pp.116-135
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    • 2019
  • Objectives : The purpose of this study is to analyze how purpura and vasculitis have been treated with Korean medicine and potentially to present with future direction of research and treatment. Methods : We searched clinical studies from the Korean databases including Oriental medicine Advanced Searching Integrated System(OASIS), Korean Traditional Knowledge Portal(KTKP), National Discovery for Science Leader(NDSL), Research Information Sharing Service(RISS), using keywords related to "Purpura" and "Vasculitis" from January 2000 to May 2019. Results : A total of 20 studies were selected for analysis. More than half of the patients provided with detailed information were under 19 year-olds, and upper respiratory infection, stress and fatigue, seasonal factor were among the most frequently stated as predisposing factors. Among many treatment modalities, herbal medicine was the most frequently used, followed by acupuncture and herbal acupuncture. 23 basic herbal medicine formulas were retrieved from 20 articles, most frequently used being Guibi-tang(歸脾湯加味), Samul-tang(四物湯加味) and Yukmijihwang-tang(六味地黃湯加味). In total, 122 Korean medicine herbs were used, most frequently used herbs being Glycyrrhizae Radix et Rhizoma(甘草), Angelicae Gigantis Radix(當歸), Poria Sclerotium(茯?) and Paeoniae Radix(芍藥). By its category, herbs were mostly classified into Tonyfying and replenishing medicinal(補益藥), Heat-clearing medicinal(淸熱藥) and Exterior-releasing medicinal(解表藥). Patients with total treatment period of 3 months or under were 2/3 of all cases provided with detailed information. Follow up periods were short in general with only 6 cases of over 6 months. The primary motive of patients to receive Korean medicine treatments was unresponsiveness or adverse effects of western medication. Conclusion : Through this literature review, we could find out tendencies of Korean medicine treatments of purpura and vasculitis up to date and some points that may have clinical significance.

Effects of Cordyceps militaris supplementation on the immune response and upper respiratory infection in healthy adults: a randomized, double-blind, placebo-controlled study (건강한 성인을 대상으로 면역증강 및 상기도 감염 예방에 대한 동충하초주정추출물의 유효성 평가 : 이중맹검 플라세보 대조 연구)

  • Jung, Su Jin;Hwang, Ji Hyun;Oh, Mi Ra;Chae, Soo Wan
    • Journal of Nutrition and Health
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    • v.52 no.3
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    • pp.258-267
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    • 2019
  • Purpose: Upper respiratory tract infections are major causes of the common cold throughout the world. Cordyceps militaris (C. militaris) is a well-known functional food for its anti-fatigue and immunomodulating activities. On the other hand, there are no reports on the protective effect against upper respiratory tract infections (URI). This study was a 12 week randomized, double-blind, and placebo-controlled trial in healthy volunteers. Methods: A total of 100 subjects 20 ~ 70 years of age with a history of at least two colds in the year were enrolled in the study. The participants were required to record any adverse events and rate any cold-related incidents in a diary during the investigation period. The efficacy end point was the symptoms and incidence of URI, and changes in cytokines, IgA and natural killer (NK) cell activity. Results: The Cordyceps militaris group over 12 weeks showed no significant impact on the incidence and symptomatology of URI compared to the placebo group. On the other hand, the experimental group showed significantly higher NK cell activity (p = 0.047) and IgA level (p = 0.035) compared to the placebo group. The NK-cell activity and IgA level were increased significantly by Cordyceps militaris over 12 weeks. Conclusion: The results suggest the possible beneficial immunomodulating effects, but the protective effects on URI could not be demonstrated under these conditions. Additional research will be needed to determine the efficacy and mechanisms of Cordyceps militaris function.

Comparison of Chin Tuck Against Resistance and Shaker Exercise on Suprahyoid and Sternocleidomastoid Muscle Activity in Stroke Older Patients with Dysphagia (삼킴 장애가 있는 뇌졸중 노인 환자에서 저항성 고개 숙이기 운동과 Shaker 운동의 목뿔위 및 목빗근 활성 비교)

  • Kim, Bon Yi;Lee, Seul;Moon, Jong Hoon;Won, Young Sik
    • 재활복지
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    • v.20 no.3
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    • pp.179-193
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    • 2016
  • Chin Tuck Against Resistance Exercise(CTARE) and Shaker exercise is used to common for strengthening of suprahyoid muscle. No previous studies was compare of two exercises for patients with dyaphagia. This study investigated the effects of CTARE and Shaker exercise on suprahyoid, sternocleidomastoid muscle activity in stroke older patients with dysphagia. Ten stroke patients with dyaphagia voluntarily participated in this study. All subjects was performed in the order in the CTARE (isometric, isokinetic), Shaker (isometric, isokinetic), and repeated each ten trials. After CTARE was performed, subjects took a 5 min wash out period to minimize muscle fatigue. Activity of suprahyoid and sternocleidomastoid muscle during two training was analyzed using surface electromyography(sEMG). Wilcoxon signed rank test was used to assess differecences for muscles activity between the effects of the CTAR and Shaker exercise within group. CTARE and Shaker exercise showed no significant difference activity in suprahyoid muscle(p > .05). CTARE showed significantly lower muscle activity in sternocleidomastoid muscle than Shaker exercise(p < .05). CTARE in stroke older patients with dysphagia may be a effective intervention to improve swallowing function than Shaker exercise.

A Study on the Factors of Life Satisfaction of the Adults with Developmental Disabilities (그룹홈 중고령 발달장애인의 생활만족도 영향요인 연구: 청년기 발달장애인과의 비교를 중심으로)

  • Roh, Seung Hyun;Kim, Cheong Seok
    • 재활복지
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    • v.22 no.3
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    • pp.69-91
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    • 2018
  • This study aims to identify factors of life satisfaction of the adults with developmental disabilities, focusing on the comparison between young and old. Data are collected through in-depth interview of the adults with developmental disabilities as well as via workers proxy responses at the group home. Regression model analysis is conducted based on 387 cases. The result shows that the young adults with developmental disabilities are more likely to satisfied with life when they evaluate job performance of workers at the group home and when they are more actively involved in community activities. For the old adults with developmental disabilities, life satisfaction is positively associated with their evaluation of job performance of workers at the group home as in the young adults. In addition, life satisfaction of the old adults is higher when they feel less fatigue. It is also higher for those with more choices on residence and higher level of social activities. The findings reveals that enhancement of life satisfaction for the old adults with developmental disabilities dwelling at group home require supports and services for health and social activities different from other ages. It shares the general ideas that service efforts should be made for needs and desires of the recipients. The present study suggests to expand our research interests to include the disabled in danger of early aging, such as the persons with Down Syndrome and the persons with intellectual disability and cerebral palsy, and look into their particular needs.

The Effects of Guided Imagery Activities Using Music on Mood States, and Physiological Responses of Psychiatric Inpatients (음악을 사용한 지시적 심상이 입원 정신질환자의 기분상태 및 생리적 변화에 미치는 영향)

  • Cho, Hyun-joo;Moon, Ji-young
    • 재활복지
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    • v.20 no.1
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    • pp.113-130
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    • 2016
  • The purpose of this study is to determine the effects of guided imagery activities using music on both mood states and physiological responses of psychiatric inpatients. The experimental group was consisted of 27 psychiatric patients participating in the guided imagery activities using music for 11 minutes. Also, the control group was formed with 27 psychiatric patients with non-musical intervention. Mood states, blood pressure, pulse and skin temperature were checked before and after session. We could see the significant difference in the score of five areas-tension, depression, anger, vigor, fatigue-showed most differences in score. Also, the score of skin temperature of both experimental group and between two groups showed significant differences, too. Therefore, we can conclude that these results were showing that guided imagery activities using music was an effective nursing intervention method for altering mood state of psychiatric patients. Besides, it seemed to have physiological impact to make patients relax tension backed up by change of skin temperature.

Comparison of the Bupropion versus Aripiprazole Adjunctive Therapy for the Treatment of Female Depression : Post-Hoc Analyses from a Randomized Prospective Open-Label Multi-Center Study (여성 우울증 환자에서 Aripiprazole과 Bupropion 부가요법의 우울증상 및 안전성에 대한 효과 비교 : 사후분석연구)

  • Keum, Mu-sung;Cheon, Eun-Jin;Lee, Kwang-Hun;Koo, Bon-Hoon;Lee, Young-Ji;Park, Young-Woo;Lee, Jong-hun;Lee, Seung-Jae;Sung, Hyung-Mo
    • Mood & Emotion
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    • v.16 no.3
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    • pp.140-151
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    • 2018
  • Objectives : The purpose of this study was to examine effects of adjunctive aripiprazole versus bupropion, on depressive symptoms of female depression. Methods : Sixty six female patients with major depressive disorders were enrolled from a six-week, randomized prospective open-label multi-center study. Participants were randomized to receive aripiprazole (2.5-10 mg/day) or bupropion (150-300 mg/day). Montgomery Asberg Depression Rating Scale, 17-item Hamilton Depression Rating scale (HAM-D17), Iowa Fatigue Scale, Drug-Induced Extrapyramidal Symptoms Scale, Psychotropic-Related Sexual Dysfunction Questionnaire scores, and Clinical Global Impression-Severity (CGI-S) were obtained at baseline and after one, two, four, and six weeks. Changes on individual items of HAM-D17 were assessed as well as on composite scales (anxiety, insomnia and drive), and on four core subscales that capture core depression symptoms. Results : Overall, both treatments improved depressive symptoms, without causing serious adverse events. There were significant differences in the HAM-D17 total score (p=0.046) and CGI-S (p=0.004), between aripiprazole and bupropion augmentation, favoring aripiprazole over bupropion. Aripiprazole revealed significantly greater effect size in depressed mood (p=0.006), retardation (p=0.005), anxiety psychic (p=0.032), and general somatic symptom (p=0.01). Conclusion : While both treatments were effective, results of this study suggested that aripiprazole may be preferable, in treating general and core symptoms of female depression.

Design and Strength Analysis of a Mast and Mounting Part of Dummy Gun for Multi-Mission Unmanned Surface Vehicle (복합임무 무인수상정의 마스트 및 특수임무장비 장착부 설계 및 강도해석)

  • Son, Juwon;Kim, Donghee;Choi, Byungwoong;Lee, Youngjin
    • The Journal of Korean Institute of Information Technology
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    • v.16 no.11
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    • pp.51-59
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    • 2018
  • The Multi-Mission Unmanned Surface Vehicle(MMUSV), which is manufactured using glass Fiber Reinforced Plastic(FRP) material, is designed to perform a surveillance and reconnaissance on the sea. Various navigation sensors, such as RADAR, RIDAR, camera, are mounted on a mast to perform an autonomous navigation. And a dummy gun is mounted on the deck of the MMUSV for a target tracking and disposal. It is necessary to analyze a strength for structures mounted on the deck because the MMUSV performs missions under a severe sea state. In this paper, a strength analysis of the mast structure is performed on static loads and lateral external loads to verify an adequacy of the designed mast through a series of simulations. Based on the results of captive model tests, a strength analysis for a heave motion of the mast structure is conducted using a simulation tool. Also a simulation and fatigue test for a mounting part between the MMUSV and the dummy gun are performed using a specimen. The simulation and test results are represented that a structure of the mast and mounting part of the dummy gun are appropriately designed.he impact amount are performed through simulation and experiments.

Effects of a Mindfulness-Based Mind-Body Intervention Program using Marine Resources on the Improvement of Sleep Quality and Mood Symptoms in Korean Female Emotional Labor Workers : A Pilot Study (해양자원을 활용한 심신치유기법이 여성 감정노동자들의 수면, 우울 및 기분 증상 개선에 미치는 효과 : 예비 연구)

  • Lee, Sang-Ah;Lee, Sung-Jae;Yook, Young-Sook;Huh, Yu-jeong;Lee, Min-Goo;Choi, Hwi-young;Lee, Jae-Hon
    • Sleep Medicine and Psychophysiology
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    • v.25 no.2
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    • pp.58-67
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    • 2018
  • Objectives: The purpose of this pilot study was to examine the effects of a mindfulness-based Body-Mind Intervention Program using marine resources on the improvement of quality of sleep, mood symptoms, and cognitive function in Korean female emotional labor workers. Methods: Twelve female workers who experienced excess emotional labor participated at the training camp program for five days in Danghangpo-ocean park, Goseung-gun, Gyeongnam Province in South Korea. Participant sleep quality, mood symptoms, and cognitive functioning before, after, and 1.5 months later were evaluated and analyzed. Results: After participating in the marine resource program, participants reported significantly decreased sleep latency. Global sleep quality, cognitive functions (attention, flexibility, and inhibition control), and mood states, including depression, tension, anger, fatigue, were also improved. These effects were generally maintained after 1. 5 months (PSQI t = 2.63, p = 0.02 ; HAM-D t = 5.92, p < 0.001). Conclusion: A Body-Mind Intervention Program using marine resources was effective in relaxing emotion-related tension and improving cognitive function. To advance this pilot study, it is necessary to carry out further research to investigate the use of marine resources in mental health interventions.

Experimental Study on Reducing Motion of Circular Cylinder in Currents (조류 중 원형실린더 형상 구조물의 거동감소를 위한 실험적 연구)

  • Lim, Jae Hwan;Jo, Hyo Jae;Hwang, Jae Hyuk;Kim, Jae Heui;Lee, Tae Kyung;Choi, Yoon Woo;Lee, Min Jun;Kim, Young Kyu
    • Journal of Ocean Engineering and Technology
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    • v.33 no.4
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    • pp.350-357
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    • 2019
  • The development of marine technology is expected to increase the demand for marine plants because of increasing oil prices. Therefore, there is also expected to be an increase in the demand for cylindrical structures such as URF (umbilical, riser, flowline) structures and spars, which are used operating in various seas. However, a cylindrical structure experiences vortex induced motion (VIM) in a current. In particular, for risers and umbilicals, it is important to identify the characteristics of the VIM because interference between structures can occur. In addition, various studies have been conducted to reduce VIM because it is the cause of fatigue damage to structures. The helical strake, which was developed for VIM reduction, has an excellent VIM reduction performance, but is difficult to install on structures and has a negative effect on heave motion. Therefore, the purpose of this study was to supplement the shortcomings of the helical strake and develop a high-performance reduction device. In the reduction device developed in this study, a string is placed around the structure inside the flow, causing vibration. The vibration of this string causes a small turbulence in the flow field, reducing the VIM effect on the structure. Finally, in this study, the 2-DOF motion characteristics of models without a suppression device, models with a helical strake, and models with a string were investigated, and their reduction performances were compared through model tests.

Effects of mixed supplementation on Hoveni dulcis Thunb extracts and Ginseng-Berry extracts on hangover curves (헛개과병추출물과 인삼열매추출물의 혼합 음료 섭취가 숙취해소에 미치는 효과)

  • Park, Noh-Hwan;Lee, Jeong-Ok;Cho, In-ho
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.3
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    • pp.359-367
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    • 2019
  • The purpose of this study was to investigate the effects of ingestion of rabies and ginseng fruit extracts on alcohol hangover, liver damage protection, fatigue recovery, and physical strength improvement. A total of 64 volunteers aged over 20 were participated in this study and the randomized and repeated measures design method was used to divide a group of participants with a random assignment. All participants were divided into 4 groups (n=16) treated with hoveni dulcis thunb extract + ginseng berry extract (ARI 1000), hoveni dulcis thunb extract, ginseng berry extract, and placebo. As a result of respiratory alcohol concentration change, the group treated with ARI 1000 was significantly lower than the group treated with hoveni dulcis thunb extract, ginseng berry extract, and placebo in 1 hour of drinking, and significantly lower than the placebo group in 2 hours and 3 hours of drinking (p<0.05). After 2 and 3 hours of alcohol consumption, blood alcohol concentration of the group treated with rabies ARI 1000 was significantly lower than those of the other 3 groups (p <0.05). In conclusion, ingestion of ARI 1000 before drinking may significantly reduce the respiratory and blood alcohol concentrations, which may induce an effect on the hangover effect.