• Archives of Plastic Surgery
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• v.41 no.4
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• pp.325-329
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• 2014

Background Liposuction is a procedure to reduce the volume of subcutaneous fat by physical force. Intracellular storage fat is composed of triglyceride, whereas circulating fat particles exist as cholesterol or triglycerol bound to carrier proteins. It is unavoidable that the storage form of fat particles enters the circulation system after these particles are physiologically destroyed. To date, however, no studies have clarified the fatal characteristics of fat embolism that occurs after the subclinical phase of free fat particles. Methods A mixture of human lipoaspirate and normal saline (1:100, 0.2 mL) was injected into the external jugular vein of rats, weighing 200 g on average. Biopsy specimens of the lung and kidney were examined at 12-hour intervals until postoperative 72 hours. The deposit location and transport of the injected free fat particles were confirmed histologically by an Oil Red O stain. Results Inconsistent with previous reports, free fat particles were transported from the intravascular space to the parenchyma. At 24 hours after infusion, free fat particles deposited in the vascular lumen were confirmed on the Oil Red O stain. At 72 hours after infusion, free fat particles were accumulated compactly within the parenchymal space near the perivascular area. Conclusions Many surgeons are aware of the fatal results and undiscovered pathophysiologic mechanisms of free fat particles. Our results indicate that free fat particles, the storage form of fat that has been degraded through a physiological process, might be removed through a direct transport mechanism and phagocytotic uptake.

• Tuberculosis and Respiratory Diseases
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• v.70 no.3
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• pp.235-241
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• 2011

Background: The rising prevalence of asthma may be associated with the rising prevalence of obesity in developed nations. There are several studies showing that obesity increases the risk of asthma in adults. We investigated the association of each body composition scale and bronchial hyper-responsiveness. Methods: This study involved a retrospective review of the existing records for 279 subjects with respiratory symptoms, who underwent a pulmonary function test, a methacholine challenge test and a body composition test between May 2007 and June 2009. Results: Of the 279 subjects, 179 (64%) were female. There was a statistically significant difference in fat free mass and in fat free mass index between the normal bronchial responsiveness group and bronchial hyper-responsiveness group (p=0.036; p=0.000). There was no significant differences in body mass index, in fat mass and fat free mass index in the normal bronchial responsiveness group and bronchial hyper-responsiveness group in males. However in females, body mass index and fat free mass index were increased in the bronchial hyper-responsiveness group (p=0.044; p=0.000). Total body water (kg), fat free mass (kg) and soft lean mass (kg) were significantly different between the normal bronchial responsiveness group and bronchial hyper-responsiveness group (p=0.002; p=0.000; p=0.000). Conclusion: This study showed significant differences in fat free mass and in fat free mass index between the normal bronchial responsiveness group and the bronchial hyper-responsiveness group. In females, BMI, soft lean mass, and total body water showed significant differences between the normal bronchial responsiveness group and the bronchial hyper-responsiveness group. We concluded that bronchial hyper-responsiveness was associated with not only body mass index but also fat free mass index in female bronchial asthma.

• Asian-Australasian Journal of Animal Sciences
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• v.30 no.8
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• pp.1105-1116
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• 2017

Objective: A meta-analysis was conducted to evaluate the effects of supplemental fat containing saturated free fatty acids (FA) on milk performance of Holstein dairy cows. Methods: A database was developed from 21 studies published between 1991 and 2016 that included 502 dairy cows and a total of 29 to 30 comparisons between dietary treatment and control without fat supplementation. Only saturated free FA (>80% of total FA) was considered as the supplemental fat. Concentration of the supplemental fat was not higher than 3.5% of diet dry matter (DM). Dairy cows were offered total mixed ration, and fed individually. Statistical analysis was conducted using random- or mixed-effects models with Metafor package in R. Results: Sub-group analysis showed that there were no differences in studies between randomized block design and Latin square/crossover design for dry matter intake (DMI) and milk production responses to the supplemental fat (all response variables, $p{\geq}0.344$). The supplemental fat across all studies improved milk yield, milk fat concentration and yield, and milk protein yield by 1.684 kg/d (p<0.001), 0.095 percent unit (p = 0.003), 0.072 kg/d (p<0.001), and 0.036 kg/d (p<0.001), respectively, but tended to decrease milk protein concentration (mean difference = -0.022 percent unit; p = 0.063) while DMI (mean difference = 0.061 kg/d; p = 0.768) remained unchanged. The assessment of heterogeneity suggested that no substantial heterogeneity occurred among all studies for DMI and milk production responses to the supplemental fat (all response variables, $I^2{\leq}24.1%$; $p{\geq}0.166$). Conclusion: The effects of saturated free FA were quantitatively evaluated. Higher milk production and yields of milk fat and protein, with DMI remaining unchanged, indicated that saturated free FA, supplemented at ${\leq}3.5%$ dietary DM from commercially available fat sources, likely improved the efficiency of milk production. Nevertheless, more studies are needed to assess the variation of production responses to different saturated free FA, either C16:0 or C18:0 alone, or in combination with potentially optimal ratio, when supplemented in dairy cow diets.

• Journal of Nutrition and Health
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• v.4 no.1
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• pp.29-40
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• 1971

For the measurement on the fat content if University Students, an intensive examination was conducted on a total of 3,030 students(male 2,577, female 453), from 16 to 25 years of age. The subjects were all students who had passed the written entrance examination for Seoul National University. Total Body Fat amount was measurement by skin-fold thickness with a skin-fold caliper(Manufactured by Cambridge Scientific Industrial Inc. U.S.A.) at four sites of the body, and it was calculated by Kim's and Lee's regression equation. As a result of this survey, the following conclusions were obtained; 1. Physical Measurements: i) The average of body height by anthropometric was male $167.95{\pm}4.85cm$ and female $156.03{\pm}4.56cm$. ii) The average body weight by anthropometric was male $56.42{\pm}5.65kg$ and female $51.29{\pm}5.34kg$. iii) The average of chest-girth by anthropometric was male $89.95{\pm}5.33cm$ and female $81.36{\pm}4.89cm$. iv) The average of sitting-height by anthropometric was male $91.23{\pm}4.98cm$ and female $86.18{\pm}4.15cm$. v) The average of arm circumference by anthropometric was male $23.76{\pm}2.17cm$ and female $22.39{\pm}1.79cm$. In all cases the male measurements were higher than the female. 2. The mean skin-fold thickness measured with a large skin-fold caliper was; At the sub-scapular: male $11.54{\pm}4.84mm$ and female $14.07{\pm}4.49mm$, Abdominal: male $10.36{\pm}7.09mm$ and female $14.95{\pm}5.47mm$, Lumbar; male $12.55{\pm}6.44mm$ and female $17.02{\pm}6.57mm$, Upper arm: male $6.28{\pm}3.71mm$ and female $11.62{\pm}3.99mm$, Total average: male $10.18{\pm}5.52mm$ and female $14.41{\pm}5.13mm$, in all cases the female measurements were higher than the male. 3. Data on body fat amounts according to body fat weight regression equation were: in male: Fat weight=10.56kg, Fat free weight=45.86kg, Fat weight/Total body mass(%)=18.71%, (Body fat amount %), Fat weight/Fat free weight(%)=23.02%, Fat free weight/Total body mass(%)=81.29%. in female: Fat weight=12.23kg, Fat free weight=39.06kg, Fat weight/Total body mass(%)=23.85%, Fat weight/Fat free weight(%)=31.31%, Fat free weight/Total body mass(%)=76.15%. The females value was higher than the males.

• Journal of Korea Association of Health Promotion
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• v.3 no.1
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• pp.24-34
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• 2005

Background: A reasonable weight reduction is to reduce fat-body mass while preserving free-fat mass. Recently, many people in Korea have been trying reckless diet therapy for weight reduction by low calory and protein diets, which gave rise to many side effects consequently. For reasonable weight reduction, this study was undertaken to investigate the influential diet factors that change body composition during short-term low calory diet. Methods: 26 healthy obese women aged 23-27 years whose BMI was greater than 24volunteered for the 6 week diet therapy from January to April in 2003. All subjects were instructed to eat approximately 1200kca1/day and write dietary diary. In the beginning of the study, the 3rd week and the 6th week, subjects' body weight and fat body weight were measured by BlA. In the 6th week, the analysis of dietary diary was conducted. Results : There was significant positive correlation between protein intake per ideal bodyweight in the first 3 weeks and free fat mass increase in the later 3 weeks (P<0.05). At the same time, fat intake in the first 3 weeks had positive correlation with free fat mass in the second 3 weeks, too(P<0.05). But, we could not find any significant values that had effect on free fat mass increase in multiple regression analysis. Conclusion: The protein intake in the first 3 weeks helps preserve fat free mass in the later 3 weeks, and has positive effects.

• Journal of Yeungnam Medical Science
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• v.20 no.1
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• pp.53-61
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• 2003

Background: Body weight is an important factor that influence the bone density in postmenopausal women except estrogen dificiency. However, different results are reported about the relationship between body composition and bone density in the postmenopausal women. We have studied the relationship between age, body weight, body mass index (BMI), waist hip ratio (WHR), muscle mass, fat mass, fat free mass and bone density. Materials and Methods: We have studied 127 persons of postmenopausal women who visited university medical center and examined the inbody 3.0 and Dual Energy X-ray Absorptiometry (DEXA) from Jan, 2001 to Jun, 2002. they didn't have any disease and didn't received hormone therapy, osteoporosis therapy or other medication that influence the bone density. Results: The numbers of study subjects is total 127 persons. Mean age is $56.9{\pm}5.14$, mean weight is $59.3{\pm}8.7kg$, mean BMI is $25.37{\pm}3.16(kg/m^2)$, mean fat mass is $20.02{\pm}5.05kg$, mean muscle mass is $37.49{\pm}4.50kg$, mean fat free mass is $39.80{\pm}4.70$, mean BMD is $0.828{\pm}0.148(g/cm^2$). In the result of linear regression analysis, age, height, weight, muscle mass, fat free mass, fat mass, BMI are significant determinants of BMD. In stepwise multiple regression analysis, age is the most significant determinant of BMD and besides age, fat free mass is the most significant determinant of BMD among body composition. Conclusion: In postmenopausal women, age, height, weight, BMI, muscle mass, fat free mass, fat mass are significant determinants of BMD and besides age, fat free mass is the most significant determinant of BMD among the body composition. So, diet and exercise that increase fat free mass will contribute to bone density increment.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.2
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• pp.113-127
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• 2010

Objectives : This study was performed to evaluate the effect of the electroacupuncture therapy on abdominal fat deposit without diet, exercise and herbal medication. It was also designed to check the changes of free fatty acid in blood and catecholamine in urine to observe the mechanism of the electroacupuncture efficacy. Methods : 10 volunteers over 85 cm(male, 90 cm) in waist circumferences were recruited, and 10 electroacupuncture treatments were applied on their abdominal subcutaneous fat area for 4-5 weeks. We measured anthropometric factors, abdominal fat area with CT scanning, and the changes of free fatty acid in blood and catecholamine in urine before treatment and after the last treatment. Results : In this study, significant changes were shown in weight, waist circumference, waist/hip ratio, body mass index and body fat percent after the electroacupuncture therapy. There were also significant decreases of visceral fat area, visceral/subcutaneous fat area ratio in CT scanning. The blood level of free fatty acid and the urine level of catecholamine were increased after treatments, but the changes were not statistically significant. Conclusions : This study showed the efficacy of the electroacupuncture therapy on the abdominal fat deposit. But significant changes couldn't be found out in free fatty acid and catecholamine. Further studies that compensate for the limitations of this study are required to confirm the mechanism of the electroacupuncture efficacy.

• The Korea Journal of Herbology
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• v.24 no.1
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• pp.15-21
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• 2009

Objectives : This study was designed to investigate the effect of water extract from Paeonia Lactiflora Pasll. with medicinal herb on plasma lipid and glucose in rats fed high fat diet. Methods : Experimental groups were divided into control diet group(C), high fat diet group(HF), high fat diet and 5% water extracts from Paeonia Lactiflora Pasll. with medicinal herb group(HFE I), high fat diet and 10% water extract from Paeonia Lactiflora Pasll. with medicinal herb group(HFE II). Weight gain, food intake, food efficiency, plasma lipid concentration and glucose were determined for 10 weeks during high fat diet. Results : In this experiment, body weight and food efficiency were significantly increase in high fat diet. High fat diet group showed elevated levels of total cholesterol, LDL-cholesterol and free fatty acid. Consumption of 10% water extract Paeonia Lactiflora Pasll. with medicinal herb lowers level of total cholesterol, LDL-cholesterol and free fatty acid. But levels of plasma triglyceride, HDL-cholesterol and glucose did not affect by high fat diet and water extract Paeonia Lactiflora Pasll. with medicinal herb Conclusions : In these results, water extract Paeonia Lactiflora Pasll. with medicinal herb in high fat diet group decreased plasma total cholesterol, LDL-cholesterol and free fatty acid. Thus the Paeonia Lactiflora Pasll. with medicinal herb might be useful in the treatment of hyperlipemia.

• The Journal of Internal Korean Medicine
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• v.37 no.6
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• pp.1012-1021
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• 2016

This study investigated the effects of Wolbiga-banha-tang (WBBT) on high fat diet-induced rats. We divided the rats into 4 groups: normal (fed a general-fat diet), control (fed a high-fat diet and no treatment), $WBBT{\times}1$ (fed a high-fat diet and 250 mg/kg of Wolbiga-banha-tang extracts), and $WBBT{\times}2$ (fed a high-fat diet and 500 mg/kg of Wolbiga-banha-tang extracts). We measured the body weight, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, free fatty acids, total lipids, AST, ALT, and CBC in the serum of the obese rats for 7 weeks. There was a significant decrease in the control group, $WBBT{\times}1$, and $WBBT{\times}2$ in triglycerides and free fatty acids. The results suggest that WBBT is effective for lowering triglycerides and free fatty acids. Therefore, WBBT may be applied to the treatment of lipid metabolism in obesity and further clinical studies are needed.

• Journal of Nutrition and Health
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• v.32 no.2
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• pp.189-196
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• 1999

This study was conducted to investigate the relationships among the levels of fasting serum insulin, free fatty acid, lipids and anthropometry in normal-weight female college students. Serum insulin and free fatty acid levels were negatively correlated. However, insulin, triglyceride, and cholesterol levels were not correlated with fat mass or BMI(body mass index). The ability of anthropometric and biochemical indicators to predict fatness could be important for epidemiologic and clinical research. In the subjects, waist cirumference was correlated with BMI, fat mass and percent body fat, and HDLC/CHOL (high density lipoprotein cholesterol/cholesterol)was correlated with body weight, BMI, and fat mass. Our data suggests than waist circumference and HDLC/CHOL are predictors of fatness, whereas WHR apears to be a less important contributor to fatness in female college students.