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http://dx.doi.org/10.22246/jikm.2016.37.6.1012

The Effects of Wolbiga-banha-tang on Obese Rats Fed a High-fat Diet  

Na, Ga-young (Dept. of Internal Medicine, College of Korean Medicine, Dong-Shin University)
Moon, Young-ho (Dept. of Internal Medicine, College of Korean Medicine, Dong-Shin University)
Lee, Hye-in (Dept. of Internal Medicine, College of Korean Medicine, Dong-Shin University)
Kim, Eun-ji (Dept. of Internal Medicine, College of Korean Medicine, Dong-Shin University)
Publication Information
The Journal of Internal Korean Medicine / v.37, no.6, 2016 , pp. 1012-1021 More about this Journal
Abstract
This study investigated the effects of Wolbiga-banha-tang (WBBT) on high fat diet-induced rats. We divided the rats into 4 groups: normal (fed a general-fat diet), control (fed a high-fat diet and no treatment), $WBBT{\times}1$ (fed a high-fat diet and 250 mg/kg of Wolbiga-banha-tang extracts), and $WBBT{\times}2$ (fed a high-fat diet and 500 mg/kg of Wolbiga-banha-tang extracts). We measured the body weight, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, free fatty acids, total lipids, AST, ALT, and CBC in the serum of the obese rats for 7 weeks. There was a significant decrease in the control group, $WBBT{\times}1$, and $WBBT{\times}2$ in triglycerides and free fatty acids. The results suggest that WBBT is effective for lowering triglycerides and free fatty acids. Therefore, WBBT may be applied to the treatment of lipid metabolism in obesity and further clinical studies are needed.
Keywords
obesity; triglyceride; free fatty acid; Wolbiga-banha-tang (WBBT);
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Times Cited By KSCI : 5  (Citation Analysis)
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