• Clinical and Experimental Pediatrics
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• 제48권8호
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• pp.857-864
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• 2005

목 적 : 인슐린 감수성 지표들은 신체계측지수인 체질량지수 및 비만도와 상관관계를 보이는 것으로 알려져 있다. 그러나 이러한 신체계측지수들이 체지방량을 잘 반영하는 것으로 알려져 있기는 하나 소아에서는 성인에 비해 그 정확도가 떨어지므로 실제로 측정한 체지방량과 인슐린 감수성 지표들 간에도 이와 같은 연관성이 있는지에 대한 연구는 없는 실정이다. 따라서 본 연구에서는 단순 소아 비만아들을 대상으로 하여, 체지방측정에 있어 비교적 객관적이며 정확한 방법으로 알려진 BIA와 DEXA로 측정한 체지방량과 인슐린 감수성 지표들 간에 어떠한 연관성이 있는지 알아보고 추후 외래에서 비만아들을 추적 관찰할 때 어느 지표가 가장 유용한지 알아보고자 한다. 방 법 : 2002년 1월부터 2004년 7월까지 중앙대학교 용산병원 비만클리닉을 방문한 28명의 단순비만 환자를 대상으로 하였다. 12시간 이상 금식 후 채혈을 하여 혈당과 인슐린 수치를 측정하였다. 같은 날 신장, 체중, 허리 둘레, 엉덩이 둘레를 계측하였고, BIA와 DEXA를 시행하여 체지방량을 구하였다. 얻어진 혈당과 인슐린 수치를 이용하여 G/I ratio, $log_{insulin}$, HOMA-IR, $log_{HOMA-IR}$, QUICKI를 구하여 체지방량과의 연관성을 알아보았다. 결 과 : 1) 인슐린 감수성 지표 중 G/I ratio만 triglyceride와 통계상 연관성이 있는 것으로 나왔다(r=-0.206, P<0.05). 이외의 $log_{insulin}$, HOMA-IR, $log_{HOMA-IR}$, QUICKI는 혈중 지질치와 관련이 없었다. 2) 비만도는 G/I ratio와 -0.209(P<0.05), $log_{insulin}$과 0.196(P<0.05), HOMA-IR과 0.238(P<0.01), $log_{HOMA-IR}$과 0.198(P<0.05), QUICKI와는 -0.224(P<0.05)로 연관성이 있는 것으로 나왔고, 체질량지수는 G/I ratio와 -0.463(P<0.01), $log_{insulin}$과 0.417(P<0.05), HOMA-IR과 0.301(P<0.01), $log_{HOMA-IR}$과 0.403(P<0.01), QUICKI와는 -0.451(P<0.01)로 나와 비만도 보다 더 인슐린 감수성 지표들과 상관성이 높은 것으로 나타났다. 3) BIA로 측정한 체지방량과 비만도 및 체질량지수 각각에 대한 상관계수는 0.612(P<0.01), 0.316(P<0.05)으로 나왔고, DEXA로 측정한 체지방량과는 각각 0.667(P<0.01), 0.512(P<0.05)로 나와 체지방량과 비만도 및 체질량지수 사이에 연관성이 있는 것으로 밝혀졌다. 4) G/I ratio는 BIA로 측정한 체지방량 및 체지방률과 각각 상관계수 -0.420(P<0.05), -0.366(P<0.05)으로 상관성을 보이고 있었고, DEXA로 측정한 체지방량 및 체지방률과도 -0.512(P<0.01), -0.449(P<0.01)로 높은 상관성을 보였다. HOMA-IR은 DEXA로 측정한 체지방량과만 상관계수 0.341(P<0.05)로 연관성을 나타냈고, 그밖에 다른 인슐린 감수성 지표들은 체지방량 및 체지방률 모두와 상관성이 없었다. 결 론 : 인슐린 감수성 지표들과 비만도 및 체질량지수와 같은 신체 계측지수들 간의 상관성에서, 인슐린 감수성 지표 특히 G/I ratio가 비만도 및 체질량지수 모두와 높은 상관성을 보였고, 체지방량 및 체지방률과 인슐린 감수성 지표와의 관계에서는 G/I ratio만이 BIA와 DEXA로 측정한 체지방량과 체지방률 모두와 연관성이 있는 것으로 나타났다. 따라서 단순 비만아의 진단 및 추적 관찰시 BMI 및 인슐린과 혈당치를 기초로 한 인슐린 감수성 지표 특히, G/I ratio의 활용이 임상에서 유용하게 사용될 수 있을 것으로 생각된다.

• 대한지역사회영양학회지
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• 제13권3호
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• pp.418-425
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• 2008

The purpose of this study was to investigate correlations between bone mineral density (BMD) and dietary and non-dietary factors in female college students. The BMD of the subjects (n = 38) was measured using DEXA (Dual Energy X-ray Absorptiometry) at lumbar spine and three femoral sites including femoral neck, ward's triangle, and femoral trochanter. Three-day 24-hour dietary recall data were collected from each subject to assess consumption levels of nutrients and food groups. The mean (${\pm}SD$) values of age, age of menarche, height, weight, body mass index (BMI), waist-to-hip ratio (WHR), fat mass, and % body fat of the subjects were 21.34 (${\pm}1.73$) years, 13.1 (${\pm}1.2$) years, 161.3 (${\pm}5.0$) cm, 53.7 (${\pm}7.2$) kg, 20.6 (${\pm}2.6$) $kg/m^2$, 0.80 (${\pm}0.04$), 15.4 (${\pm}4.4$) kg, and 28.2 (${\pm}4.7$), respectively. The BMD values of lumbar spine, femoral neck, ward's triangle, and femoral trochanter as T-value were $1.150{\pm}0.13\;g/cm^2$, $0.932{\pm}0.11\;g/cm^2$, $0.850{\pm}0.13\;g/cm^2$, and $0.721{\pm}0.10\;g/cm^2$, respectively. The daily mean energy intake of the subjects was 1660.6 kcal. The intake levels of carbohydrate, calcium, iron, vitamin C, and folic acid were lower than the KDRIs, while those of fat, phosphorus, sodium, vitamin A, and vitamin $B_6$ were higher than the KDRIs. Significantly negative correlation were detected between consumption of fat and oils and the BMD of all sites measured (p < 0.05). Potato and starch intake was negatively correlated to the BMD of femoral neck and word's triangle (p < 0.05). The intake of cereals was found to be negatively correlated to the BMD of ward's triangle (p v 0.05). There was also negative correlation of intake of soybeans and products with the BMD of lumbar spine (p < 0.05). Weight and muscle mass were positively correlated to the BMD of both lumbar spine and femurs (p < 0.01). Significantly positive correlations between BMI, and fat mass and the BMD of lumbar spine were observed (p < 0.001). Additionally fat mass was positively correlated to the BMD of femoral neck. WHR and % body fat were positively correlated to the BMD of lumbar spine (p < 0.05). Negative correlation was found between a serum calcium level and the BMD of femoral neck (p < 0.05). In summary non-dietary factors generally showed significant correlations with the BMD of lumbar spine, while several dietary factors showed significant correlations with the BMD of femurs.

• Journal of the Korean Data and Information Science Society
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• 제24권2호
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• pp.303-310
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• 2013

체지방 감량에 대한 효과를 분석하고자 실험에 참가한 체지방율이 30% 이상인 42명의 여대생을 대상으로 일반폰을 사용하는 그룹과 스마트폰을 사용하는 그룹으로 나누어서 측정자료를 2주 간격으로 정리하여 8주간에 걸친 체지방 및 관련자료를 얻었다. 이 실험자료를 바탕으로 혼합모형을 이용하여 분석한 결과 AR(1)의 공분산행렬이 가장 적합한 모형으로 선택되었으며, 시점 간의 상관계수는 0.838로 상당히 밀접한 관련을 보여주었다. AR(1)의 공분산행렬을 설정하여 분석한 결과 처리간의 차이에서 스마트폰의 사용자가 일반폰의 사용자보다 0.654kg 정도의 체지방 감량 효과를 보여주었으며, 시간이 지날수록 체지방 감소효과가 있음을 알 수 있다. 그러나 처리와 시간과의 교호작용은 존재하지 않는다. 또한 실험실시 전의 체지방값과 총콜레스테롤은 유의하게 나타났으며, 섭취하는 칼로리는 약간 관련이 있으나, 허리엉덩이비율은 유의하지 않는 것으로 판명되었다.

• 한국식품과학회지
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• 제41권3호
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• pp.307-312
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• 2009

체중이 정상이면서 체지방률 함량이 30% 이상인 여성을 대상으로 CLA 보충과 운동 여부가 체지방함량과 체중 및 혈당, 혈중 지질 농도에 미치는 영향에 대하여 살펴 본 결과는 다음과 같다. 실험 대상자들의 평균 연령은 22세였으며, 실험이 진행되는 동안 대상자들은 식이 조절을 하지 않았다. 실험 대상자들의 실험 후 체중과 BMI, 체지방 함량의 변화를 살펴본 결과, CLA-운동군이 placebo-비운동군에 비해 체중과 BMI가 유의적으로 작았으며, 체지방 함량도 적은 것으로 나타났다. 또한, 복부지방을 나타내는 허리둘레도 CLA-운동군이 placebo-비운동군과 비교하여 유의적으로 감소하여 CLA를 섭취하고 운동을 하는 것이 운동을 하거나, CLA만 섭취하는 것보다 체중 조절에 더 효과적인 것으로 나타났다. 대상자들의 평균 공복혈당, TG, total cholesterol, LDL-C, HDL-C은 모두 정상 범위에 속하였고, CLA를 섭취하거나 운동을 하는 경우 혈중 HDL-콜레스테롤의 함량을 증가시키는 것으로 나타났으나, CLA와 운동을 병행하는 경우 상승효과를 보이지는 않았다. 이러한 결과, CLA를 보충함으로써 체중 조절을 하는 것보다는 CLA와 운동을 함께 병행하는 것이 체중 조절에 효과적이며, 혈중 지질 농도를 개선시킬 수 있을 것으로 사료된다.

• 한방비만학회지
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• 제18권2호
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• pp.152-158
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• 2018

한약을 결합한 감로수 절식요법이 여성의 체성분 변화에 미치는 영향을 알아보기 위해 2018년 8월 17일부터 2018년 10월 24일까지 대전대학교 둔산한방병원 여성의학비만센터 외래로 내원하여 절식요법을 시행한 여성 환자 11명을 대상으로 감식기 시작일, 회복식기 종료일에 시행한 체성분검사 결과를 분석하였다. 분석 결과 절식 후 체중은 $2.52{\pm}0.86kg$, 체지방량은 $1.02{\pm}0.65kg$, 골격근량은 $0.83{\pm}0.62kg$, 세포외수분비는 $0.002{\pm}0.003$, 기초대사량은 $32.91{\pm}23.06kcal$, 복부 둘레는 $1.76{\pm}1.47cm$만큼 유의하게 감소하였다. BMI, 내장지방단면적, 복부지방두께도 절식요법 후 유의한 감소를 나타냈다. 이와 같은 결과로 미루어 한약을 결합한 감로수 절식요법은 외래로 내원하는 여성 비만 환자에게 적용하는 단기 절식 프로그램으로 활용될 수 있을 것이라 생각된다.

• 대한임상전기생리학회지
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• 제2권3호
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• pp.13-24
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• 2004

The purpose of this study is to reveal the effect of electrical stimulation of body composition in obese person. Subjects were 30s to 40s aged healthy workers(2004. 3. 8~4. 17) in the S general Hospital in Suwon and they were brought to manage obesity. Subjects were divided into control group(Female<0.85, Male<0.90) and study group(Female>0.85, Male>0.90) by WHR(waist-hip ratio) that is measured by Automatic body composition analyzer(InBody 3.0). And we divided the study group with randomized methods into group A(n=8) and group B(n=8). Then we compared and analyzed the change of muscle mass, body fat, abdominal girth, WHR, BMI(body mass index) after application of electrical stimulation, three times a week, for 30 minutes in each session with 50 Hz of pulse frequency, $20\;{\mu}s$ or $250\;{\mu}s$ of pulse duration. There was statistically meaningful decrement of body fat(p<0.05) and abdominal girth(p<0.05) but not of body weight, muscle mass, WHR and BMI in the control group after application of electrical stimulation with 50 Hz, $20\;{\mu}s$. There were meaningful change of abdominal girth(p<0.05), WHR(p<0.05) and BMI(p<0.05), but not of body weight, muscle mass and body fat after application of electrical stimulation with 50 Hz, $20\;{\mu}s$ in group A. We applied electrical stimulation with 50 Hz, $250\;{\mu}s$ in group B, then there were meaningful change of body weight(p<0.05), body fat(p<0.01), abdominal girth(p<0.01), WHR(p<0.05) and BMI(p<0.01) but not of muscle mass only. Consequently, the pulse duration is the main parameter of electrical stimulation that affect the body composition of obese person in this study and if we combined the diet control to reduce blood components we could have better result. So it would be more effective to manage localized obesity(in abdomen, thigh, upper arm, etc.) if you apply electrical stimulation considering the pulse duration.

• 대한지역사회영양학회지
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• 제11권6호
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• pp.785-792
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• 2006

The purpose of this study was to investigate the nutritional status before and after gastrectomy of gastric cancer patients in Jeonbuk Province. The subjects were 136 patients with gastrectomy of gastric cancer. We assessed the nutritional status before and after an operation by general characteristics (age, clinicopathological stage, type of operation, method of reconstruction), anthropometric characteristics (height, weight, skeletal muscle mass, body fat mass, body mass index (BMI), percent body fat, arm muscle circumference AMC, arm circumference AC) and biochemical characteristics (hemoglobin Hb, hematocrit Hct, mein corpuscular volume MCV, mean corpuscular hemoglobin MCH, total lymphocyte count TLC, serum albumin, serum transferrin). Mean ages were 60.0 yrs in males and 58.8 yrs in females. Age, clinicopathological stage, types of operation and reconstruction methods were not significantly different between males and females. Weight, skeletal muscle mass, body fat mass, BMI, percent body fat, AMC and AC significantly deteriorated by gastrectomy. There were severe weight losses in males and females after gastrectomy. Hemoglobin, Hct, MCV, MCH, TLC, albumin and transferrin significantly deteriorated by gastrectomy. After gastrectomy, subjects who were assessed as malnounrished in Hb and Hct were increased in male and those who were assessed as malnounrished in Hb were increased in females. These results suggest that a nutrition intervention, specially for energy, protein and iron, is necessary to improve the nutritional status of gastric cancer patients with gastrectomy.

• 대한물리의학회지
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• 제16권1호
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• pp.33-39
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• 2021

PURPOSE: This study compared the body composition according to the sport of short-distance and middle & long-distance athletes to identify the factors that affect the body composition. METHODS: Forty-eight athletes selected as youth national athletes in 2019 participated in the study. The study participants measured the length of the lower extremities, body composition, and anaerobic ability. An independent sample t-test was conducted to compare the body composition according to the event. In addition, the Pearson correlation was performed to identify the factors that influence the body composition. RESULTS: The leg length of the Short and Middle & long-distance athletes were similar (p = .584). On the other hand, there were differences in the body fat percentage (p = .001), lean percentage (p = .001), and BMI (p = .001). In addition, the body fat percentage was correlated with the lean body mass (r = .419) and BMI (r = .447). Furthermore, the lean body mass was correlated with the BMI (r = .849) and the peak power (r = .662) and mean power (r = .686) of the anaerobic capacity. Moreover, the BMI was correlated with the peak power (r = .490) and mean power (r = .543) of the anaerobic capacity. The peak power of the anaerobic ability was correlated with the mean power (r = .931). CONCLUSION: The body composition differed according to the sport. The body fat percentage correlated with the lean body mass and the BMI. The lean body mass correlated with the BMI, peak power of anaerobic ability, and mean power. The BMI correlated with the anaerobic capacity.

• 대한통합의학회지
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• 제3권2호
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• pp.17-28
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• 2015

Purpose: The purpose of this study was intended to investigate the effect on the body composition of the dormitory-type middle school students by implementing the complexed exercise program. Method: As subjects of the study, the dormitory-type middle school students in Chungbuk, divided into 2 grade experimental group(N=46), 3 grade control group(N=49). Group-specific arbitration method, was applied to complexed exercise program (experimental group) and running group (control group). Each training courses 30 minutes 5times weekly, examined the changes in body composition to examine a total of 6-week course effectively. Result: The results were compared with change of Height, Muscle mass, Fat mass, Lean body mass and BMI. Experimental group were significant(p<.05) compared to the control group. Height, Weight, Muscle mass, Fat mass, and BMI of control group wasn't significant(p>.05). Also there were significant difference(p<.05) between groups on Height, Muscle mass, Fat mass and Lean body mass post-test measure. Conclusion: Looking in total from the above results, it is suggested that it is possible to complexed exercise program 6 weeks improves body composition of the dormitory-type middle school students. Therefore, it is possible that the application of complexed exercise program is to effective in improvement of body composition of the dormitory-type middle school students.

• Journal of Applied Biological Chemistry
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• 제59권1호
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• pp.49-56
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• 2016

The current study investigated the anti-obesity effect of Cissus quadrangularsis extracts (CQR-300) and its molecular action mechanism on obese mice induced high-fat diet (HFD). To induce the obesity, mice were fed a HFD for 6 weeks and then fed HFD only or HFD with CQR-300 at 50 and 200 mg/kg. Then, body weight gain and white adipose tissue weights were measured. We investigated the reduction in body fat and the regulation of fatty acid synthesis was measured by dual energy X-ray absorptiometry and real-time PCR with Western blot, respectively. In vitro study, CQR-300 inhibited pancreatic lipase activity. The CQR-300 treatment was significantly decreased the body weight gain and adipocytes size as well as white adipose tissues weights in HFD-induced obese mice. Furthermore, CQR-300 reduced the body fat and fat mass with regulating of adipose tissue hormones as leptin. Treatment with 50 mg/kg CQR-300 showed effectively lower expression levels of adipogenesis/lipogenesis related genes and proteins such as CCAAT/enhancer binding protein ${\alpha}$ ($C/EBP{\alpha}$), peroxisome proliferator-activated receptor ${\gamma}$ ($PPAR{\gamma}$), Sterol regulatory element binding protein-1c (SREBP-1c), and fatty acid synthase (FAS) in white adipose tissue (WAT) as compared with the HFD fed only mice. These results suggest that the CQR-300 has an anti-obesity effect via inhibition of lipase activity, decrease the body fat mass by regulating the adipogenesis and lipogenesis related genes and proteins in epididymal adipose tissue with evaluate body fat reduce in the HFD-induced obese mice.