• Journal of Haehwa Medicine
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• v.18 no.1
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• pp.129-138
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• 2009

purpose : The purpose of this paper is to report that the fasting treatment was quick and effective against the menopausal depression. So that the further study on the fasting treatment for the menopausal depression is expected. methods : This fasting treatment included three periods. The first was to reduce the food intake and the sodium intake as well. The second was for fasting for two weeks. During this period, the patient drank 250cc of the fermented herbal juice and 2500cc of water a day and had the lactobacillus supplement twice a day. Then, the third was for rebuilding. During the rebuilding period, the patient followed the limited sodium diet for two weeks. results : After the fasting treatment done, the symptoms that patient complained before went away. The BDI score went down from 19 to 3. And, of course, the patient lost her body weight and the fat. conclusions : The 49-year-old female patient in the menopause period was suffering from the lack of energy, depression, sleeping disorder, constipation, and weight gain. She took the fasting treatment along with the acupuncture at the holistic medical clinic, 'The Seasons' from Jan 16th 2009 to Feb 27th(the main fasting period was for 14 days). The BDI score indicated that she had the depression as her score was 19 at the first examination. After the treatment was completed, the BDI score dropped to 3. Therefore, I report the immediate effect of the fasting treatment again the depression. Women are twice as likely to get the depression as men. Especially, the women in menopause period tend to get the depression as they are facing the physical, mental, and social changes which can act as the stressors. Besides, women tend to get depressed when they gain weights. Thus, I suggest the further study on the fasting treatment should be carried on so to apply it more positively to various problems in the field of the psychiatry.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.14 no.1
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• pp.94-104
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• 2001

A Reports were done on 3 cases of proriasis, 1 case of chronic urticaria which were admition and treated by fasting therapy in Dept. surgery, opthalmology & otolaryngology, college of Oriental Medicine, Kyungsan University, Pohang, Korea, from March 1999 to October 2000. The results were as follows: 1. In the case chronic urticaria, symptom and sign(jtching, wheal, erythema), except of pigment, were showed conciderable improvement. 2. In the case proriasis, it is different of person, bellow 5cm sized erythematous popules were disappeared during fasting therapy, above 5cm sized erythematous papules and plaque were improved by using medication after fasting therapy. Silver-white colored scales was improved about $50-60\%$, itching was disappeared during fasting therapy. 3. After fasting therapy there was a recurrence, but about $40-50\%$ decreased symptoms were showed. 4. Besides upper diagnosis and treatment based on overall of symptoms and signs considered by documentary investigation, medications by Sasang prescription also can be expected good treatment effect.

• Korean Journal of Veterinary Research
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• v.38 no.4
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• pp.946-956
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• 1998

Fifteen mongrel dogs (14 male and 1 female) were injected intravenously with 30mg of streptozotocin and 50mg of alloxan monohydrate per kilogram of body weight to induce diabetes mellitus. Before treatment with streptozotocin and alloxan fasting serum glucose concentration was determined every other day or thrice a week (Monday, Wednesday, Friday) for 3 months. Among 15 dogs 4 dogs developed diabetes mellitus and survived more than 9 weeks without injection of insulin. After treatment fasting serum glucose and hemoglobin $A_1$ concentrations of the 4 dogs were determined every other day or thrice a week. Fasting serum glucose concentration increased acutely from 24 hours after treatment and then showed severe fluctuation. Hemoglobin $A_1$ concentration increased gradually until 7~9 weeks after treatment and then showed very slow increase afterwards. Correlation of hemoglobin $A_1$ to fasting glucose concentration was relatively weak(r = 0.10~0.80). Hemoglobin $A_1$ and fasting glucose concentration of preceding 7 week showed very high correlation (r = 0.98~0.99). It was indicated that hemoglobin $A_1$ concentration in chemically induced diabetic dogs reflects mean glucose concentration of preceding 7~9 weeks.

• The Journal of Korean Medicine
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• v.31 no.5
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• pp.146-166
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• 2010

Objective: Few data were available on glycemic control at the early prediabetic stage, though it is the important stage to prevent diabetes mellitus. The purpose of this research was to examine the glycemic control effects of herb medicine treatment (DA-9802) in prediabetic stage patients Methods: In this randomized, single blind, placebo-controlled study, we compared Sanyak extract (DA-9802) with placebo for the treatment of glycemic control effects in prediabetic stage patients. 45 volunteers who satisfied the requirements were enrolled in the study. They took Sanyak extract (DA-9802) or placebo treatment three times a day for 8 weeks. Blood sugar, Total Symptom Score (TSS) and blood serum were measured at weeks 0, 4, and 8. Results: In the DA-9802 group, fasting blood sugar changes between before 8 weeks significantly decreased. Fasting blood sugar, fasting blood sugar gaps between before and after treatment for 8 weeks, insulin changes and C-peptide significantly decreased at 8 weeks compared with those of the placebo group. Conclusion: Herb medicine treatment (DA-9802) is effective in glycemic control on prediabetic stage.

• Journal of Gastric Cancer
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• v.23 no.2
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• pp.253-263
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• 2023

Purpose: Although chylous ascites is a frequent complication of radical gastrectomy for gastric cancer, proper diagnostic criteria and optimal treatment strategies have not been established. This study aimed to identify the clinical features of chylous ascites and evaluate the treatment outcomes. Materials and Methods: We retrospectively analyzed the data of patients who underwent radical gastrectomy between 2013 and 2019. Diagnosis was made when milky fluid or elevated triglyceride levels (≥100 mg/dL) appeared in the drains without a preceding infection. The clinical features, risk factors, and treatment outcomes were assessed according to the initial treatment modalities for fasting and non-fasting groups. Results: Among the 7,388 patients who underwent radical gastrectomy for gastric cancer, 156 (2.1%) experienced chylous ascites. The median length of hospital stay was longer in patients with chylous ascites than in those without (median [interquartile range]: 8.0 [6.0-12.0] vs. 6.0 [5.0-8.0], P<0.001). Low body mass index (adjusted odds ratio [aOR]=0.9; P<0.001), advanced gastric cancer (aOR=1.51, P=0.024), open surgery (reference: laparoscopic surgery; aOR=1.87, P=0.003), and extent of surgical resection (reference: subtotal gastrectomy, total gastrectomy, aOR=1.5, P=0.029; proximal gastrectomy, aOR=2.93, P=0.002) were associated with the occurrence of chylous ascites. The fasting group (n=12) was hospitalized for a longer period than the non-fasting group (n=144) (15.0 [12.5-19.5] vs. 8.0 [6.0-10.0], P<0.001). There was no difference in grade III complication rate (16.7% vs. 4.2%, P=0.117) or readmission rate (16.7% vs. 11.1%, P=0.632) between the groups. Conclusions: A fat-controlled diet and medication without fasting provided adequate initial treatment for chylous ascites after radical gastrectomy for gastric cancer.

• Journal of the Korean Dietetic Association
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• v.15 no.4
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• pp.343-355
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• 2009

To elucidate the effect of a 4 week dietary supplementation with pumpkin water extract on serum lipid and fasting glucose levels, 41 female collegians residing in the Gyeonggi area were recruited. The subjects were divided into three groups: placebo-control (PC, n=11), treatment A (TA, 100 ml/day, n=13), and treatment B (TB, 300 ml/day, n=17). Total serum cholesterol, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, triglyceride (TG), and fasting glucose were analyzed. The average age, height, weight, and body mass index of the subjects were 21.3 years, 161.1 cm, 53.0 kg, and 20.4 $kg/m^2$, respectively. The average total cholesterol, HDL-cholesterol, LDL-cholesterol, TG, and fasting glucose level (mg/dl) were 171.4${\pm}$26.1, 63.5${\pm}$11.4, 92.6${\pm}$22.9, 76.8${\pm}$32.0, and 89.1${\pm}$8.2, respectively. There were no significant differences among the three groups in any measured parameters, and between the pre- and post-study values of the all parameters. The results indicated that the 4 week pumpkin water extract supplementation (100 ml, 300 ml) did not influence the serum total cholesterol, HDL-cholesterol, LDL-cholesterol, TG and fasting glucose level in female collegians.

• Korean Journal of Human Ecology
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• v.9 no.1
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• pp.81-88
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• 2006

IGFs and IGFBPs have an important role in controlling glucose homeostasis. This study was conducted to investigate the changes of insulin-like growth factor(IGF)-I. IGF-II and IGF binding proteins (IGFBPs) on fasting and postprandial state in Korean diabetes, Twenty eight healthy subjects and fifty seven diabetic patients participated in this study. The healthy subjects were not knowingly suffered from any disease and were not receiving any medical treatment, and diabetic subjects were undergo medical treatment, continuously. Weight and height were measured and body mass index (BMI) was calculated as weight (kg) divided by the square of height (m2). Blood pressure was measured. Plasma lipid profiles were analyzed by enzymatic methods, plasma Insulin and glucose levels were measured in fasting and postprandial state, respectively. The levels of serum IGFs and IGFBP-3 were measured by radioimmunoassay (RIA). The levels of glucose and insulin were significantly higher in diabetes than normal subjects on fasting as well as postprandial state (p<0.0l). The levels of IGF-I was significantly lower in diabetes than normal subjects, however in postprandial state, there was no significant difference between diabetes and control subjects, The levels of IGF-II were significantly lower in diabetes than control subjects both fasting and postpradial state, The level of IGFBP-3 were not significantly different between diabetes and normal subjects. Fasting IGF-I, IGF-II and IGFBP-3 levels were positively correlated with those levels on postprandial state, fasting IGe levels of IGF-I levels were positively correlated with fasting insulin levels, and postprandial IGF-I levels were positively correlated with fasting glucose, postprandial insulin and postprandial insulin levels, plasma triglyceride levels were correlated with plasma triglyceride levels. The IGFBP-3 levels were not correlated with IGF components, glucose, insulin and plasma lipids, These results demonstrate that in diabetes, the components IGF-I/IGFBPs system were significantly correlated with plsma glucose and insulin levels both fasting and postprandial state.

• Journal of Korean Medicine for Obesity Research
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• v.10 no.1
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• pp.49-56
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• 2010

This study was performed to report the effectiveness of modified fasting therapy using very-low-calorie-diet on a patient with obesity. The patient was diagnosed as severe obesity and participated in a 14-day fast with the Signature, a liquor which is made from fermented medical herbs and carbohydrates (intake <600 kcal/day) accompanying 7 prefasting relief days, and 16 days with stepwise reintroduction of food. The fasting patient also received intensive oriental medical treatments such as acupuncture, moxibustion, cupping therapy and was encouraged to take more than two hours' of walking exercise a day. We have evaluated the efficacy of treatments by measuring the changes of body composition and blood chemistry according to each period of fasting therapy. After treatment, Body Fat Mass of the patient was decreased more than Muscle Mass and the level of AST, ALT was decreased to normal range. These results suggest that the modified fasting therapy was effective on the patient with obesity.

• Korean Journal of Adult Nursing
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• v.18 no.5
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• pp.809-818
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• 2006

Purpose: The purpose of this study was to evaluate the effect of antioxidant vitamins and magnesium supplementation on fasting blood glucose and lipids in patients with type 2 diabetes. Methods: This study is a unequivalent control group pretest-posttest design. Seventyone subjects with type 2 diabetes who were recruited from home visiting clients of a public health center, completed the trial. The experimental group entered a 12-week treatment period with antioxidant vitamins and magnesium and the control group with no antioxidant vitamins and magnesium. Results: Serum level of fasting blood glucose decreased from $134.7mg/d{\ell}$ to $125.0mg/d{\ell}$ and total-cholesterol decreased from $215.5mg/d{\ell}$ to $198.2mg/d{\ell}$ in the experimental group. No changes in fasting blood glucose and total-cholesterol were demonstrated in the control group. Conclusions: A short-term supplementation with antioxidant vitamins and magnesium can reduce fasting blood glucose and total-cholesterol in patients with type 2 diabetes. The continuous effect of this supplementation and the beneficial effect on the prevention of diabetes complication still needs to be demonstrated.

• The Journal of the Korean dental association
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• v.47 no.2
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• pp.90-101
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• 2009

The aim of this study was to appraise the influence of conventional periodontal treatment on metabolic control in Korean type 2 diabetic patients. In addition, their periodontal change was compared with non-diabetic patients. Before and after treatment, it was performed to measure periodontal and metabolic indices in thirteen type 2 diabetic patients. Periodontal indices included plaque index, gingival index, bleeding on probing, probing pocket depth, gingival recession, and clinical attachment level. Metabolic indices included glycated hemoglobin(HbA1c), fasting plasma glucose, fasting plasma insulin, total cholesterol, triglyceride, and HDL-cholesterol. Plaque index, gingival index, bleeding on probing, probing pocket depth, and gingival recession showed significant improvements in the statistics. Diabetic patients showed no statistically significant differences in the changes of periodontal indices compared with non-diabetic patients. HbA1c values decreased in five of the thirteen subjects and fasting plasma glucose levels were reduced in four of the seven subjects after periodontal treatment. All five subjects whom HOMA values were calculated in showed the increases of insulin secretions. The results of this study ascertained the possibility of the better glycemic contol after conventional periodontal treatment in Korean type 2 diabetic patients and diabetes were well healed of their periodontal diseases after the treatment.