The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Glycemic Control Effects of Sanyak (Dioscoreae rhizoma) extract in Prediabetic Stage Patients

산약 추출물이 당뇨병 전단계 피험자의 혈당조절에 미치는 영향

  • Cho, Suck-In (Dept. of Acupuncture and Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Son, Mi-Won (Dong-A Pharm. co., LTD.) ;
  • Hong, Kwon-Eui (Dept. of Acupuncture and Moxibustion, College of Oriental Medicine, Daejeon University)
  • 조석인 (대전대학교 한의과대학 침구학교실) ;
  • 손미원 (동아제약) ;
  • 홍권의 (대전대학교 한의과대학 침구학교실)
  • Received : 2010.07.28
  • Accepted : 2010.08.30
  • Published : 2010.09.30
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Abstract

Objective: Few data were available on glycemic control at the early prediabetic stage, though it is the important stage to prevent diabetes mellitus. The purpose of this research was to examine the glycemic control effects of herb medicine treatment (DA-9802) in prediabetic stage patients Methods: In this randomized, single blind, placebo-controlled study, we compared Sanyak extract (DA-9802) with placebo for the treatment of glycemic control effects in prediabetic stage patients. 45 volunteers who satisfied the requirements were enrolled in the study. They took Sanyak extract (DA-9802) or placebo treatment three times a day for 8 weeks. Blood sugar, Total Symptom Score (TSS) and blood serum were measured at weeks 0, 4, and 8. Results: In the DA-9802 group, fasting blood sugar changes between before 8 weeks significantly decreased. Fasting blood sugar, fasting blood sugar gaps between before and after treatment for 8 weeks, insulin changes and C-peptide significantly decreased at 8 weeks compared with those of the placebo group. Conclusion: Herb medicine treatment (DA-9802) is effective in glycemic control on prediabetic stage.

Keywords

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