• Genomics & Informatics
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• v.7 no.3
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• pp.152-158
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• 2009

Although the genetic basis for bone mineral density (BMD) has been studied by many groups so far, genes responsible for this complex trait has not been completely revealed. In order to localize quantitative trait loci (QTLs) for BMD variation in Asian population, the study was designed using a group of Mongolian population, a genetically closed population with a homogeneous lifestyle. BMD was measured at the left and right wrists and ankles using DEXA in 1,082 participants from 142 families. Genotyping of 13 polymorphic microsatellite markers on chromosome 13 (average spacing 8-9 cM) and two-point and multipoint linkage analysis were performed. In two-point linkage analysis, we identified two markers, D13S175 (6.03 cM) and D13S265 (68.73 cM) that had LOD scores greater than 1 for left ankle (LOD=2.09, LOD=1.49, respectively). We also found a marker D13S175 (6.03 cM) with a high LOD for left wrist (LOD=1.49) and the markers D13S265 (68.73 cM) and D13S217 (17.21 cM) for the right wrist (LOD= 1.82, LOD= 1.62, respectively). Among these significant marker regions, only two regions at 17 cM (13p11) and 65 cM (13q21) for the right wrist overlapped with major QTLs reported in following multipoint linkage analysis (LOD= 1.7549, LOD=1.4462, respectively). This study provides the possible evidence of the presence of QTLs affecting right wrist BMD in Mongolian populations on 13p11 and 13q21. Modest evidence was also found for genes affecting left ankle and left wrist BMD on 13p13.

• Atmosphere
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• v.24 no.1
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• pp.17-27
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• 2014

In this study, the observational environment for sunshine duration at Seoul and Daegu Automated Synoptic Observing Systems (ASOSs) was analyzed using a numerical model. In order to analyze the effects of topography and buildings on observational environment for sunshine duration, the model domains including the elevated building and mountainous areas around Seoul and Daegu ASOSs were considered. Three dimensional topography and buildings used as input data for the numerical model were constructed using a geographic information system (GIS) data. Solar azimuth and altitude angles calculated for the analysis period (one-week for each season in 2008) in this study were validated against those by Korea Astronomy and Space Science Institute (KASI). The starting and ending times of sunshine duration observed at ASOSs largely differed from the respective sunrise and sunset times simply calculated using solar angles and information of ASOSs' latitude and longitude, because uneven topography and elevated buildings around ASOSs cut off sunshine duration right after the sunrise and right before the sunset. The model produced the sunshine indices for Seoul and Daegu ASOSs with the time interval of one minute and the period of one week for each season and we compared the hourly averaged indices with those observed at the ASOSs. One week of which the cloudiness is lowest for each season is selected for analysis. Not only the adjacent buildings but also distant buildings and mountain cut off sunshine duration right after the sunrise and right before the sunset. The buildings and topography cutting off sunshine duration were found for each analyzing date. It was suggested that, in order to evaluate the observational environment for sunshine duration, we need to consider even the information of topography and/or building far away from ASOSs. This study also showed that the analyzing method considering the GIS data is very useful for evaluation of observational environment for sunshine duration.

• Imaging Science in Dentistry
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• v.53 no.4
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• pp.291-302
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• 2023

Purpose: Early detection of carotid stenosis can reduce cardiovascular risk. In this study, the maximum-carotid intima-media thickness (CIMT), the mean-CIMT, and the presence of plaque were examined in healthy young Thai adults. Additionally, correlations between CIMT and cardiovascular risk factors were assessed. Materials and Methods: Left and right carotid arteries of 302 participants(15-45 years old) were scanned, with CIMT measured at the far walls of the common carotid artery, carotid bulb, and internal carotid artery. Demographics and risk factors were assessed using a questionnaire. Ten random participants were re-scanned after 4 weeks. Results: The study included 123 (40.70%) male and 179 (59.30%) female participants. The max-CIMT, mean-CIMT, and plaque thickness were 0.400±0.100, 0.403±0.095 and 1.520±0.814 mm, respectively. Male participants had significantly higher CIMT values for nearly all locations and age groups. The right-sided CIMT values were higher for all locations. The carotid bulb had the greatest CIMT values(0.437±0.178 mm), followed by the common (0.403±0.095 mm) and internal(0.361±0.099 mm) carotid arteries. Plaque was present in 18 locations (1.00%), affecting 15 participants (4.97%). These plaques were found in the right carotid bulb (n=9; 0.50%), left carotid bulb (n=7; 0.39%), and right internal carotid artery (n=2; 0.11%). Adjusted multivariable regression revealed significant positive associations between CIMT and male, increased age and "other" occupation (P<0.05). Conclusion: Both max-CIMT and mean-CIMT were approximately 0.4 mm. Plaque was observed in 4.97% of patients, with an average thickness of 1.5 mm. The most influential risk factors for increased CIMT were sex, age, and occupation.

• Journal of the Korean Society of Costume
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• v.55 no.3 s.93
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• pp.94-107
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• 2005

Kokuryo mural tombs are located in Jipan and Pyongyang, where were capital Cities of Kokuryo. Although there are many studies performed about costumes in Kokuryo mural tombs so far, the studies comparing regional differences are rare. In this study, we tried to compare about the costumes in Kokuryo mural tombs between Jipan, where was the capital city in early period (BC37-AD426) and Pyongyang, where was the capital city for 241 years after the King Jang Su moved.(AD427-AD668) The results of this study are as following. There are differences between Jipan and Pyongyang in the shape of Chima(skirt) and the direction of Yeomim (adjusting the necklines). While there was only one type, long and narrow pleated skirt in Jipan area, another type of Chima was existed in Pyongyang area including the one in Jipan. Also, the direction of Yeomim was different. Left was popular in Jipan while it was right in Pyongyang. Moreover there are no man's Po(coat) with straight collar which was considered as a basic shape in Kokuryo mural tombs costumes so far. Also we found that Baji(pants) was an ordinary woman's costume, not only for underwear.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2004.11a
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• pp.353-357
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• 2004

The construction competition is more deepened with the enterprise possibility increase which it follows in the regulation relaxation back against the construction market penetration which carries and the instability of market is added an extra weight and it solves the aspect where also the profitability which is caused by with low price bidding decreases. Against a productivity with the overcome plan it is researched plentifully and the far for a productivity improvement, there is so far to construction, the productivity being used with only include meaning, is to a practical affairs and the application ver)r as the level which is feeble is a possibility of doing. It is like that and the research develops the producing district possibility of new steel-frame work and in the actuality which sees the production volume of steel-frame work and a construction accomplishment process effectively and to be right numerical figures it does it plans it controls and manages the place ultimate objective which it puts.

• Journal of the Korean Home Economics Association
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• v.40 no.12
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• pp.119-129
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• 2002

This research aims at finding out situation on purchasing clothes for kids, size recognition and fitting to provide basic data in order to establish standard sizes for kids' clothes. A survey was conducted to 360 mothers who have children ranging from first to third grade in elementary school on clothes purchasing method, wearing situation, criteria in deciding size and fitting preference. In terms of data analysis, frequency, percentage, mean, $X^2$-test, ANOVA and Duncan-test were used via SPSS PC program. The result is as follows; 1. While the recognition on brand was high, the recognition on body size was low: as a result, it is believed that it would be effective to mark the weight along with the brand. 2. Many times, they would select one or two size bigger on all items and they would go for a regular or one that fits as far as filling is concerned showing that it is different from adult clothes. 3. As far as obese kids, they would choose based on the diameter, so the diameter item is right but they are too long in general. The length question should be given special attention when manufacturing clothes for obese kids.

• The Journal of the Acoustical Society of Korea
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• v.19 no.3E
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• pp.33-39
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• 2000

This study investigated whether the adjacency principle. demonstrated in a perceived visual space, can be applied to auditory space. In order to demonstrate an auditory adjacency principle, multiple sound sources were varied in direction and distance in an acoustically absorbant space. Specifically, a NEAR sound source was located 10° to the left of the listener's midline at a distance of 2 meters; a FAR sound source was located 10° to the right at a distance of 5 meters. These sources served as perceptual reference points with respect to the localization of three test sounds, all at a distance of 3 meters. Two of three test sounds were directionally closer to the NEAR and FAR reference sounds, respectively. The other was between the reference sources directionally. The listener was asked to judge the perceived distances and the loudness of the three test sounds and the two reference sounds. The results indicated that the apparent distances of the test sounds were most determined by the disparity of distance between each test sound and the reference sound most directionally adjacent to it. Therefore, the findings offer evidence that the adjacency principle can be applied to the auditory space.

• The Korean Journal of Physiology
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• v.27 no.1
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• pp.51-55
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• 1993

The effects of a calcium channel blocker and an activator on the release of atrial natriuretic peptide (ANP) were investigated in rats. They were volume expanded (VE) up to 5% of the body weight over 30min by being infused with iso-oncotic saline. Following VE, plasma ANP concentration markedly increased in association with increases in the right atrial pressure. Addition of either nifedipine ($0.4{\mu}m/min$) or Bay K 8644 ($0.4{\mu}m/min$) in the infusate potentiated the VE-induced release, although neither of them affected the right atrial pressure. The nifedipine added group showed a lower mean arterial pressure than the Bay K added group throughout the infusion period. VE decreased plasma renin concentration, the magnitude of which was attenuated by nifedipine but not by Bay K. It may be hypothesized that a decrease in cytoplasmic calcium is primary stimulus far the ANP release, and an increase plays o role in secondary liberation of the ANP accumulated in the interstitium into the lumen of the atria through myocardial contraction. further studies will be needed to confirm the hypothesis.

• Journal of Yeungnam Medical Science
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• v.33 no.2
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• pp.142-145
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• 2016

Gastric cancer is the most common cancer in Korean males and can easily spread to distant organs such as the liver, lungs, brain, or bones. However, skin metastasis, particularly of the eye, is rare. Metastatic eyelid cancer is extremely rare; metastases from internal organs have not been reported so far. We recently experienced a patient with metastatic eyelid cancer from adenocarcinoma of the stomach. A 62-year-old female was admitted with a right upper eyelid mass and foreign body sensation. She had a history of stomach cancer of 3 years. She was treated by chemotherapy and radiotherapy for pathologic fracture. After receiving supportive care for 2 years, the mass appeared on her right pupil. Punch-biopsy of the mass was performed and histological examination revealed adenocarcinoma, the same as the initial histological result. We report this case with a review of related literature.

• Journal of Chest Surgery
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• v.21 no.6
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• pp.1111-1116
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• 1988

Neurofibromatosis is very rare syndrome characterized by abnormal cutaneous pigmentation and numerous skin tumors was described by Smith in 1849, which is inherited as an autosomal dominant trait. Von Recklinghausen reported 2 cases of multiple skin and subcutaneous tumors in 1982. Malignant peripheral nerve tumors, although generally rare, are one of the most characteristic malignant tumors associated with Neurofibromatosis. We have experienced 3 cases of malignant Schwannoma in neurofibroma patients from 1982 to 1988 for 6 years at Thoracic and Cardiovascular surgery department, College of Medicine, Yonsei University, Seoul, Korea. l. One is 62 years old female who was taken total hysterectomy followed by irradiation treatment due to Uterine Carcinoma 21 years ago. She had a large bulging mass on left anterior chest wall and was taken enbloc resection of tumor including rib confirmed malignant Schwannoma. 2. Another is 18 years old female who had large bulging mass on right chest wall and pleural effusion in right thoracic cavity. Thoracentesis revealed a large amount of lymphocytes misdiagnosed of Tbc, pleurisy with Neurofibromatosis. We performed tissue biopsy on bulging mass and the specimen was confirmed malignant Schwannoma 2 months after first diagnosis of Tbc. pleurisy. She was not accessible to radical resection because of far advanced malignant Schwannoma at that time. 3. Third case is 28 years old male who was taken enbloc resection of tumor including rib due to Neurofibroma with Neurofibromatosis at M. hospital 6 months ago. But he had rapid growing mass at operation site again and taken tissue biopsy confirmed of malignant Schwannoma. He was not accessible to enbloc resection due to malignant Schwannoma extending to mediastinal structures.