• Korean Journal of Ornithology
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• v.25 no.2
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• pp.69-76
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• 2018

Sexual dimorphism in birds refers to male-female differences in body size, plumage, color and/or behavior. In general, many seabirds, including the family of Laridae, are monomorphic in plumage-color, which makes the determination of sex difficult in the field because both parents also tend to share a great portion of parental care. The development of an inexpensive sexing tool facilitates understanding the degree of sex-specific parental care in the evolution of the life history. Here, we developed a non-invasive method for the determination of sex using the bill-head morphometric of known captive pairs and applied this tool to wild pairs to document factors underlying male-female parental care during the incubation period of Saunders's gulls (Saundersilarus saundersi). Males exhibited relatively larger bill-head ratios than their mates within naturally formed pairs in captivity, resulting in the determination of sex in12 wild pairs at the nest during the incubation period. Males and females equally shared the incubation role during the daytime, attending the nest at a high rate of 95%. However, the male's proportion of nest attentiveness greatly increased with time towards sunset, presumably reflecting the male duty for nighttime incubation. The present study provides a non-invasive method for the determination of sex in a monomorphic seagull species and highlights how male-female incubation behavior is associated with time of the day, rather than other ecological conditions.

• Korean Journal of Heritage: History & Science
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• v.45 no.4
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• pp.22-37
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• 2012

Storage facility of the pre-historic Korea is classified into the subterranean, ground and overground types. The rectangular-shaped subterranean Storage facilities have been identified in the Pungnaptoseong, the Gong mountain fortress site and the Gwanbukri site. Feature no. 196 at Gyeongdang District in Pungnaptoseong yielded a large quantity of glazed potteries, and a wooden storage at the Gwanbukri site contained a large amount of fruit seeds. These storage facilities might be functioned as the warehouse for the highest group rather than the storage for the emergency such as war and flooding and stipend of government officials. This article subdivided into "state storage" on the concept of the former that "royal storage" on the concept of the latter. If it look on the state storage at large, this include the royal storage too. But it subdivided to help article understand because Baekjae changed from state storage to royal storage by change and specialization of system after 4th. The reason why the diversification of storage pits was closely related to the unification of local polities and the concentration of political power in the state-level. Therefore, it might reflect the political circumstances the ruling elites attempted to heighten their authority in terms of the organizing tax collecting system. And divided the time of storage is confirmed separative storage pits in the suburbs of capital city. There is hight probability of top local polities or nation that have possessional a role. This is to cover on frequent war in the Three States. On the other hand, state storage is located around ancent road that linked castle gate that is divided into center and periphery depending on function and position of storage. Center is located royal storage focusing in the presumed royal palace that periphery is located state storage to provide service to the public. It is presumed that located with the government office.

• The Journal of the Korea Contents Association
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• v.19 no.9
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• pp.81-91
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• 2019

Recently, the nation has been suffering from a variety of problems, such as the rapid aging of the population and the weakening of the family's role due to rapid industrialization, such as the problem of supporting the elderly or the decline in the quality of supporting them. Among them, the issue of supporting the sentiment of the elderly is a major issue in terms of the quality of the stimulus. The best solution would be to resolve this issue of emotional support through various physical and human support. However, due to various limitations, access to efficient utilization of resources is being sought, among which support efforts through the convergence of digital technologies need to be noted. In this study, we took note of the problems of aging population shortage due to aging phenomenon and the problems of the emotional side of the problem of declining quality of the service, and analyzed the types of digital technology applied to support the emotional side through the convergence of digital technology. Among them, the Commission proposed emotional support through smart speakers, confirming the possibility of supporting the elderly through smart speakers. In addition, the Commission proposed guidelines for smart speaker communication systems to support the sentiment of older adults by conducting an in-depth interview with the In-Depth interview with the evaluation of the usability of smart speakers for older people. Based on the results of this study, it is expected that it will be the basic data for designing a communication system when developing smart speakers to support the emotions of the elderly.

• Journal of Life Science
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• v.29 no.2
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• pp.256-264
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• 2019

Lymphotoxin ${\beta}$ receptor ($LT{\beta}R$), a member of the tumor necrosis factor receptor family, plays an important role in lymphoid tissue's architecture and organogenesis. In contrast, MLCK and ROCK play critical roles in the regulation of stress fiber (SF) formation in cells. To determine whether $LT{\beta}R$ stimulation in fibroblastic reticular cells (FRCs) is involved in these signaling pathways, myosin light chain kinase inhibitor-7 (ML-7) was used to inhibit them. ML7-treated FRCs completely blocked SFs and showed retraction and shrinkage processes comparable to those observed in agonistic anti-$LT{\beta}R$ antibody-treated cells. The inhibition of ROCK activity with Y27632-induced changes in actin cytoskeleton organization and cell morphology in FRCs. Actin bundles rearranged into SFs, and phospho-myosin light chain (p-MLC) co-localized in FRCs. We checked the level of Rho-guanosine diphosphate (RhoGDP)/guanosine triphosphate (GTP) exchange activity using FRC lysate. When $LT{\beta}R$ was stimulated with agonistic anti-$LT{\beta}R$ antibodies, Rho-GDP/GTP exchange activity was markedly reduced. Regarding $LT{\beta}R$ signaling with a focus on MLCK inhibition, we showed that the phosphorylation of MLCs was reduced by $LT{\beta}R$ stimulation in FRCs. Cytoskeleton components, such as tubulin, b-actin, and phospho-ezrin proteins acting as membrane-cytoskeleton linkers, were produced in de-phosphorylation, and they reduced expression in agonistic anti-$LT{\beta}R$ antibody-treated FRCs. Collectively, the results suggested that MLCK and ROCK were simultaneously responsible for SF regulation triggered by $LT{\beta}R$ signaling in FRCs.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.3
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• pp.249-256
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• 2021

Asthma is a chronic inflammatory airway disease. There are many factors including genetic and environmental factors that influence asthma. The mitogen-activated protein kinase (MAPK) pathway is involved in maintaining the T helper cells 1 and 2 (Th1/Th2) balance and plays an important role in the development of asthma. In this study, the correlation between the NDFIP2 gene that regulates the MAPK pathway and asthma was analyzed. The genetic polymorphism of the NDFIP2 gene was analyzed between 193 asthma patients and 3,228 healthy controls in Korea. As a result, 4 single nucleotide polymorphisms (SNPs) showed a significant correlation (P<0.05) and high relative risk with asthma. Among them, rs2783122 of NDFIP2 showed a statistically significant association with asthma (P-value=9.76×10^-6, odds ratio (OR)=1.67, 95% confidence interval (CI)=1.33~2.10). In the SNP imputation on the NDFIP2, 16 SNPs were discovered, and all of them showed significant correlation with asthma and high odds ratio. The genotype-based mRNA expression analysis revealed that the group of minor alleles of rs1408049 showed increased mRNA expression. Increased NDFIP2 expression causes the activation of the MAPK pathway, and this may influence the development of asthma. In conclusion, the polymorphisms of NDFIP2 are associated with asthma development and this can provide the basis for new guidelines for the management of asthma in the Korean population.

• Journal of Digital Convergence
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• v.18 no.12
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• pp.389-399
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• 2020

Diverse official policies in community are available for caregivers to take care of the elderly in the US and the UK. This study aims to examine the recent changes in government supports based on The Recognize, Assist, Include Support and Engage (RAISE) in the US, and those by Carer Act 2014 in the UK, to take any good lessons for Korean policy. Caregivers will play a new role to develop innovative treatment for patient-centered care. The UK strengthens to provide various efforts for working carers while assuring economic efficiency in labor market with empirical evidence. The major four ways to support carers were developed agreed with the acknowledge of caregiving value and their human right; financial support, direct services for carers, flexible work time, and advocacy. Korean supports policies for carers in long-term care and social welfare will be more effective in community care system if more evidence based policies are prepared.

• Journal of the Korean Society for information Management
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• v.38 no.1
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• pp.1-23
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• 2021

Small libraries have continued to be extended since 2013 enactment of regulations requiring establishment of small libraries in multi family housing complex not less than 500 households and the 'Living SOC Project' of national government. Gwangmyeong city designated the year of 2020 as the 'year of citizen autonomy' sharing the authority with citizens and publicly announced its plan to rapidly extend the living and cultural spaces as a part of that extension. Likewise, as the social environment and the need of users are expected to change, it seems that the small libraries in Gyangmyeong City must prepare a plan for practicing a long and mid term practices in responding to that change. Thus, this Study tries to make a suggestion for a plan for the policy for revitalization of small libraries in order to handle those changing social environment and the need of users. For this, a survey and in-depth group interview were conducted for the operators of the small libraries in Gyangmyeong City. As a result of this Study, the following policies are suggested: first, improvement of support system for improving operational system, strengthening of cooperative system of public libraries, and strengthening of role of public small libraries, strengthening of public characters of private small libraties and differentiated support through evaluation based on abilities; and second, it is necessary for utilization of circulating librarians and professional volunteers, sharing of materials through mutual lending of books, associate librarians having term of office and revitalization of small library conference by regions.

• Korean Journal of Cognitive Science
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• v.32 no.4
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• pp.169-191
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• 2021

With the development of artificial intelligence(AI), the jobs of many human experts are threatened, and this also applies to the legal profession. This study attempted to investigate whether AI can actually replace humans in the legal profession, especially the role of judges making final judgments. For this purpose, from the perspective of uniqueness neglect, this study was conducted to confirm the effect of involvement and the severity on acceptance of the judgment made by the AI judge (Experiment 1) and the AI jury (Experiment 2). The involvement was manipulated as if the subject who was sentenced for committing a crime was his or her family (mother, father) or stranger, and the severity was manipulated by the extent of the damage, the perception of the crime, and the number of applied crimes. In Experiment 1, the interactive effect of involvement and severity was found. Specifically, when the involvement was low, the acceptance of AI judges was higher in high severity (vs. low severity). Conversely, when the involvement was high, the acceptance of AI judges was higher in low severity (vs. high severity). The same interactions as in Experiment 1 occurred in Experiment 2. Specifically, when the involvement was low, a larger number of AI jury members were allocated in high severity (vs. low severity). On the other hand, when the involvement was high, the number of AI juries increased in low severity (vs. high severity). This study has implications in that it is the first experimental study in Korea on artificial intelligence legal judgment and that it presents the prospects for the jobs of legal experts.

• BMB Reports
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• v.55 no.2
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• pp.87-91
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• 2022

Aurora kinase is a family of serine/threonine kinases intimately associated with mitotic progression and the development of human cancers. Studies have shown that aurora kinases are important for the protein kinase C (PKC)-induced invasion of colon cancer cells. Recent studies have shown that aurora kinase A promotes distant metastasis by inducing epithelial-to-mesenchymal transition (EMT) in colon cancer cells. However, the role of aurora kinase A in colon cancer metastasis remains unclear. In this study, we investigated the effects of aurora kinase A on PKC-induced cell invasion, migration, and EMT in human SW480 colon cancer cells. Treatment with 12-O-tetradecanoylphorbol-13-acetate (TPA) changed the expression levels of EMT markers, increasing α-SMA, vimentin, and MMP-9 expression and decreasing E-cadherin expression, with changes in cell morphology. TPA treatment induced EMT in a PKC-dependent manner. Moreover, the inhibition of aurora kinase A by siRNAs and inhibitors (reversine and VX-680) suppressed TPA-induced cell invasion, migration, and EMT in SW480 human colon cells. Inhibition of aurora kinase A blocked TPA-induced vimentin and MMP-9 expression, and decreased E-cadherin expression. Furthermore, the knockdown of aurora kinase A decreased the transcriptional activity of NF-κB and AP-1 in PKC-stimulated SW480 cells. These findings indicate that aurora kinase A induces migration and invasion by inducing EMT in SW480 colon cancer cells. To the best of our knowledge, this is the first study that showed aurora kinase A is a key molecule in PKC-induced metastasis in colon cancer cells.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.40 no.4
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• pp.49-57
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• 2022

This study was conducted with the aim of investigating the garden architectural characteristics of Villa d'Este, which occupies a major role in the exploration of the contrasting background, location, and spatial composition characteristics of Italian Renaissance gardens. The survey for the study was divided into a literature survey and a field survey, and the details are as follows. First, in the mid-to-late 16th century, the villa was built under the direction of Cardinal Ippolito d'Este, and afterwards, the ownership of the villa was restored to the Italian government in 1850 due to financial difficulties. The Villa d'Este, which suffered another damage, is now operated with many visitors after going through the restoration process. Second, in the case of location, it has the characteristics of Urbana located in the city center and has valley-type topographical conditions located at the foot of the mountain.Third, in the case of spatial composition, it is orthogonal to the axis, and each part of the garden is developed, influenced by the contrast principles such as the installation of the Cortile del Belvedere and Villa Madama in the early 16th century. The main building is located in the hills so that you can see the garden and the surrounding scenery at a glance. Fourth, among the components, there were stairs, logia, courtyard, and grotto, fountains, cascades, ponds, and vegetation such as laurels, thorn trees.