• Journal of the Korean Society of Radiology
• /
• v.85 no.2
• /
• pp.381-393
• /
• 2024

Purpose Metabolic abnormalities in hepatic encephalopathy (HE) cause brain edema or demyelinating disease, resulting in symmetric regional cerebral edema (SRCE) on MRI. This study aimed to investigate the usefulness of the clustering analysis of SRCE in predicting the development of brain failure. Materials and Methods MR findings and clinical data of 98 consecutive patients with HE were retrospectively analyzed. The correlation between the 12 regions of SRCE was calculated using the phi (φ) coefficient, and the pattern was classified using hierarchical clustering using the φ² distance measure and Ward's method. The classified patterns of SRCE were correlated with clinical parameters such as the model for end-stage liver disease (MELD) score and HE grade. Results Significant associations were found between 22 pairs of regions of interest, including the red nucleus and corpus callosum (φ = 0.81, p < 0.001), crus cerebri and red nucleus (φ = 0.72, p < 0.001), and red nucleus and dentate nucleus (φ = 0.66, p < 0.001). After hierarchical clustering, 24 cases were classified into Group I, 35 into Group II, and 39 into Group III. Group III had a higher MELD score (p = 0.04) and HE grade (p = 0.002) than Group I. Conclusion Our study demonstrates that the SRCE patterns can be useful in predicting hepatic preservation and the occurrence of cerebral failure in HE.

• Journal of Korean Society of Steel Construction
• /
• v.16 no.6 s.73
• /
• pp.793-805
• /
• 2004

The main objective of this paper is to evaluate the ductility and strength factors that are key components of the response modification factor for special steel moment-resistant frames. The ductility factors for special steel moment-resistant frames were calculated by multiplying the ductility factor for SDOF systems and the MDOF modification factors. Ductility factors were computed for elastic and perfectly plastic SDOF systems undergoing different levels of inelastic deformation and periods when subjected to a large number of recorded earthquake ground motions. Based on the results of the regression analysis, simplified expressions were proposed to compute the ductility factors. Based on previous studies, the MDOF modification factors were also proposed to account for the MDOF systems. Strength factors for special steel moment resisting frames were estimated from the results of the nonlinear static analysis. A total of 36 sample steel frames were designed to investigate the ductility and strength factors considering design parameters such as number of stories (4, 8, and 16 stories), seismic zone factors (Z = 0.075, 0.2, and 0.4), framing system (Perimeter Frames, PF and Distributed Frames, DF), and failure mechanism (Strong-Column Weak Beam, SCWB, and Weak-Column Strong-Beam, WCSB). The effects of these design parameters on the ductility and strength factors for special steel moment-resisting frames were investigated.

• Journal of the Korean Geotechnical Society
• /
• v.20 no.5
• /
• pp.99-107
• /
• 2004

Anisotropic characteristics of deformation are important to understand the particular behavior in the pre-failure state of soils. Recent experiments show that cross-anisotropic moduli of granular soils can be expressed by functions of normal stresses in the corresponding directions, which is closely linked to micromechanical characteristics of particles. Granular soils are composed of a number of particles so that the force-displacement relationship at each contact point governs the macroscopic stress-strain relationship. Therefore, the micromechanical approach in which the deformation of granular soils is regarded as a mutual interaction between particle contacts is one of the best ways to investigate the anisotropic elastic deformation of soils. In this study, a numerical program based on the theory of micromechanics is developed. Generalized contact model for the irregular contact surface of soil particles is adopted to represent the force-displacement relationship in each contact point far the realistic prediction of anisotropic moduli. To evaluate the model parameters, a set of analytical solutions of anisotropic elastic moduli is derived in the isotropic stress condition. A detailed procedure to determine the model parameters is proposed with emphasis on the practical applicability of micromechanical program to analyze the elastic behavior of the granular soils.

• Journal of Korean Society of Steel Construction
• /
• v.17 no.2 s.75
• /
• pp.227-241
• /
• 2005

This paper presents a practical and realistic Life-Cycle Cost (LCC) optimum design methodology for steel bridges considering the long-term effect of environmental stressors such as corrosion and heavy truck traffics on bridge reliability. The LCC functions considered in the LCC optimization consist of initial cost, expected life-cycle maintenance cost, and expected life-cycle rehabilitation costs including repair/replacement costs, loss of contents or fatality and injury losses, road user costs, and indirect socio-economic losses. For the assessment of the life-cycle rehabilitation costs, the annual probability of failure, which depends upon the prior and updated load and resistance histories, should be accounted for. For the purpose, Nowak live load model and a modified corrosion propagation model, which takes into consideration corrosion initiation, corrosion rate, and repainting effect, are adopted in this study. The proposed methodology is applied to the LCC optimum design problem of an actual steel box girder bridge with 3 continuous spans (40m+50m+40m=130m). Various sensitivity analyses are performed to investigate the effects of various design parameters and conditions on the LCC-effectiveness. From the numerical investigation, it has been observed that local corrosion environments and the volume of truck traffic significantly influence the LCC-effective optimum design of steel bridges. Thus, these conditions should be considered as crucial parameters for the optimum LCC-effective design.

• Journal of Korean Society of Steel Construction
• /
• v.29 no.6
• /
• pp.411-422
• /
• 2017

In this study, to investigate the seismic performance of beam-column joints using concrete-encased and -filled circular steel tube(CEFT) columns, two types of tests were performed: (1) column - flange tension test and (2) beam - column joint cyclic load test. In column - flange tension test, test parameters were concrete encasement and connection details: flange width and strengthening rebar. Five specimens were tested to investigate the load-carrying capacity and the failure mode. Test results showed that increase of flange width from 200mm to 350mm result in increase of connection strength and stiffness by 61% and 56%, respectively. Structural performances were further improved with addition of tensile rebars by 35% and 92%, respectively. In cyclic loading test, three exterior beam-column joints were prepared. Test parameters were strengthening details including additional tensile rebars, thickened steel tube, and vertical plate connection. In all joint specimens, flexural yielding of beam was occurred with limited damages in the connection regions. In particular, flexural capacity of beam-column joint was increased due to additional load transfer through tube - beam web connection. Also, connection details such as increase of tube thickness and using vertical plate connection were effective in improving the resistance of panel zone.

• Clinical and Experimental Reproductive Medicine
• /
• v.25 no.3
• /
• pp.251-260
• /
• 1998

It is well known that the clinical test for responsibility of accurate fertilization capacity in male partners is very important to diagnose and treat the infertility. However, it has been reported that the traditional semen analysis cannot accurately predict fertilization and pregnancy potential. The present study was performed to evaluate the acrosomal reaction to ionophore challenge (ARIC) test as a prognostic indicator for fertilization of sperm and oocyte in an in vitro fertilization and embryo transfer (IVF-ET) program. From March 1996 to Februry 1997, 30 couples undergoing IVF program were allocated to this study group. All female partners in the study group were 35 years old or less and their serum level of basal follicle stimulating hormone (FSH) and estradiol $(E_2)$ were normal. All the male partners have normal parameters of semen analysis. The ARIC tests were performed on the day of ovum pick up and in vitro insemination in all the male partners. The controlled ovarian hyperstimulation (COH) using luteal long protocol of gonadotropin releasing hormone (GnRH) agonist was used in all couples for IVF-ET. The acrosomal reaction with $10{\mu}l$ of 10% DMSO was induced spontaneously in $10.1{\pm}9.8%$, and acrosomal reaction with calcium ionophore A 23187 was induced in $27.4{\pm}18.1%$, and the ARIC value was $17.4{\pm}16.2%$. There were no significant correlation between the ARIC value and the fertilization rate ($r^2$=0.044, p=0.268). There were also no significant correlation between the ARIC value and the percentage of the grade I, II embryos ($r^2$=0.046, p=0.261). On the basis of above results, it was suggested that ARIC test might not be a useful prognostic indicator for fertilization in IVF-ET in male partners with normal parameters of conventional semen analysis. We guessed that IVF-ET could be performed to the patients primarily without universal appilcation of ARIC test to all male partenrs, and if fertilization failure occurs, the micro assisted fertilization (MAF) such as intracytoplsmic sperm injection (ICSI) might be used as an alternative mode of treatment with acceptable success rate.

• The Journal of Advanced Prosthodontics
• /
• v.5 no.3
• /
• pp.287-295
• /
• 2013

PURPOSE. This study investigated the effect of laser parameters and air-abrasion on the peel strength of silicon-based soft denture liner to different denture resins. MATERIALS AND METHODS. Specimens (N=180) were prepared out of three different denture base resins (Rodex, cross-linked denture base acrylic resin; Paladent, heat-cured acrylic resin; Deflex, Polyamide resin) ($75mm{\times}25mm{\times}3mm$). A silicon-based soft denture liner (Molloplast B) was applied to the denture resins after the following conditioning methods: a) Air-abrasion ($50{\mu}m$), b) Er,Cr:YSGG laser (Waterlase MD Turbo, Biolase Technology) at 2 W-20 Hz, c) Er,Cr:YSGG laser at 2 W-30 Hz, d) Er,Cr:YSGG laser at 3 W-20 Hz, e) Er,Cr:YSGG laser at 3 W-30 Hz. Non-conditioned group acted as the control group. Peel test was performed in a universal testing machine. Failure modes were evaluated visually. Data were analyzed using two-way ANOVA and Tukey's test (${\alpha}$=.05). RESULTS. Denture liner tested showed increased peel strength after laser treatment with different parameters ($3.9{\pm}0.4-5.58{\pm}0.6$ MPa) compared to the control ($3.64{\pm}0.5-4.58{\pm}0.5$ MPa) and air-abraded groups ($3.1{\pm}0.6-4.46{\pm}0.3$ MPa), but the results were not statistically significant except for Paladent, with the pretreatment of Er,Cr:YSGG laser at 3 W-20 Hz. Polyamide resin after air-abrasion showed significantly lower peel strength than those of other groups ($3.1{\pm}0.6$ MPa). CONCLUSION. Heat-cured acrylic resin, PMMA, may benefit from Er,Cr:YSGG laser treatment at 3 W-20 Hz irradiation. Air-abrasion of polyamide resins should be avoided not to impair their peel bond strengths to silicon-based soft denture liners.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.41 no.2
• /
• pp.254-262
• /
• 2016

With the increased demand for automotive radar systems, mutual interference between vehicles has become a crucial issue that must be resolved to ensure better automotive safety. Mutual interference between frequency modulated continuous waveform (FMCW) radar system appears in the form of increased noise levels in the frequency domain and results in a failure to separate the target object from interferers. The traditional fast fourier transform (FFT) algorithm, which is used to estimate the beat frequency, is vulnerable in interference-limited automotive radar environments. In order to overcome this drawback, we propose a high-resolution frequency estimation technique for use in interference environments. To verify the performance of the proposed algorithms, a 77GHz FMCW radar system is considered. The proposed method employs a high-resolution algorithm, specially the multiple signal classification and estimation of signal parameters via rotational invariance techniques, which are able to estimate beat frequency accurately.

• Journal of Chest Surgery
• /
• v.32 no.12
• /
• pp.1065-1077
• /
• 1999

Background : Ventricular assist devices(VADs) are being used for patients in postcvardiotomy cardiogenic shock status bridge to cardiac transplant settings and in post-myocardial infarction cardiogenic shock. The VAD which was developed at the Deparment of medical engineering in Dankook University College of Medicine was a pneumatically driven device and can maintain pulsatile flow. The goal of this study is to develop animal experimental models using the VAD and to clarify the reliability and hemodynamic property adequacy of end organ perfusion durability and severity of thrombotic-hemolytic tendency of the device. Material and Method : The pneumatic VAD was applied to 8 adult female lambs, We examined some hemodynamic parameters such as arterial blood pressure pulmonary capillary wedge pressure(pcwp) pulmonary artery pressure(PAP) left atrial pressure hour urine output cardiac index VAD flow EKG to determine the reliability of the VAD and hemodynamic compatibility of the experimental animals within 24 hours of experiment. We also observed the end organ perfusion durability of the VAD and thrombotic-hemolytic property of the VAD after 24 hours of VAD insertion. Result: We could monitor all hemodynamic parameters including pcwp PAP cardiac index EKG, adn hour urine as true clinical settings. We observed that the reliability of the VAD was excellent and the hemodynamic property of the experimental animal and end organ perfusion were adequate within 24 hours of experiment. In four lambs surviving 24 hours after insertion the reliability of the VAD and end organ perfusion were excellent and no thrombotic-hemolytic tendency was noted. However after 15 days of experiment the diaphragm of the VAD was torn and it was recommende that the durability of the VAD should be extended. Conclusion : e conclude that the pneumatic VAD developed at Dankook University Biomedical Engineering has good hemodynamic property and low thromboembolic tendency and presents adequate end organ perfusion but we noted that the durability of the device should be expanded further. It will be possible to do more reliable experiment in the future according to the animal experimental method developed in this study especially with the heart failure models.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.25 no.5
• /
• pp.15-23
• /
• 2021

In this paper, service life for RC(Reinforced Concrete) substructure subjective to carbonation was evaluated through deterministic and probabilistic method considering field investigation data and Design Code(KDS 14 20 40). Furthermore changes in service life with increasing COV(Coefficient of Variation) and equivalent safety index meeting the same service life were studied. From the investigation, the mean and its COV of cover depth were evaluated to 70.0 ~ 90.0 mm and 0.2, respectively. With intended failure probability of 10.0 % and 70 mm of cover depth, service life decreased to 137 years, 123 years, and 91 years with increasing COV of 0.05, 0.1, and 0.2, respectively. In the case of 80 mm of cover depth, it changes to 179 years, 161 years, and 120 years with increasing COV. The equivalent safety index meeting the same service life from deterministic method showed 1.66 ~ 3.43 for 70 mm of cover depth and 1.61 ~ 3.24 for 80 mm of cover depth, respectively. The various design parameters covering local environment and quality condition in deterministic method yields a considerable difference of service life, so that determination of design parameters are required for exposure conditions and parameter variation.