• Clinical and Experimental Pediatrics
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• v.55 no.10
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• pp.393-396
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• 2012

Trisomy 14 mosaicism is a rare chromosome disorder characterized by delayed development, failure to thrive, and facial dysmorphism. Only approximately 30 trisomy 14 mosaicism cases have been reported in the literature because trisomy 14 is associated with early spontaneous abortion. We report a case of a 17-month-old girl with abnormal skin pigmentation, delayed development, facial dysmorphism, and failure to thrive with the 47,XX,+14/46,XX chromosome complement.

• Journal of the Korean Society of Safety
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• v.33 no.6
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• pp.37-41
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• 2018

Process safety technology has developed from qualitative methods such as HAZOP (hazard and operability study) to semi-quantitative methods such as LOPA (layer of protection analysis), and quantitative methods are actively studied these days. Quantitative risk assessment (QRA) is often based on fault tree analysis (FTA). FTA is efficient, but difficult to apply when failure events are not independent of each other. This problem can be avoided using a Markov process (MP). MP requires definition of all possible states, and thus, generally, is more complicated than FTA. A method is proposed in this work that uses an MP model and a Weibull distribution model in order to construct a reliability model for multiple dependent failures. As a case study, a pressure safety valve (PSV) is considered, for which there are three kinds of failure, i.e. open failure, close failure, and gas tight failure. According to recently reported inspection results, open failure and close failure are dependent on each other. A reliability model for a PSV group is proposed in this work that is to reproduce these results. It is expected that the application of the proposed method can be expanded to QRA of various systems that have partially dependent multiple failure states.

• Geomechanics and Engineering
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• v.29 no.2
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• pp.193-205
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• 2022

The face stability of shield tunnelling is the most important control index for safety risk management. Based on the reliability of the transparent clay (TC) model test, a series of TC model tests under different buried depth were conducted to investigate the progressive failure mechanism of tunnel face. The support pressure was divided into the rapid descent stage, the slow descent stage and the basically stable stage with company of the local failure and integral failure in the internal of the soil during the failure process. The relationship between the support pressure and the soil movement characteristics of each failure stage was defined. The failure occurred from the soil in front of the tunnel face and propagated as the slip zone and the loose zone. The fitted formulas were proposed for the calculation of the failure process. The failure mode in clay was specified as the basin shape with an inverted trapezoid shape for shallow buried and appeared as the basin shape with a teardrop-like shape in deep case. The implications of these findings could help in the safety risk management of the underground construction.

• The Journal of the Society of Stroke on Korean Medicine
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• v.22 no.1
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• pp.45-56
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• 2021

■ Background Heart Failure with Preserved Ejection Fraction(HFpEF) is a heart failure that appears to have normal contraction function. In the case of HFpEF, no pharmacological therapy has been found to improve clinical prognosis, so it should be approached as an symptomatic treatment, therefore alternatives are needed due to concerns over adverse effects such as electrolyte imbalance caused by medication. ■ Case report A 81 year old female patient with Heart Failure with Preserved Ejection Fraction(HFpEF) patient complained dyspnea. Herbal prescription Mokbanggi-tang and Oryeongsan was administered on 6th day and 8th day respectively since the symptoms started. The NYHA Classification and Chest X-ray had been evaluated during the treatment period. Until the 7th day, the patient was classified as Class II, and when discharged from the hospital on the 28th day, it gradually improved and was classified as Class II. Chest X-Ray took on 2nd day showed pleural effusion and it was aggravated until 13th day. Follow up Chest X-Ray showed improving state of pleural effusion from 20th day and gradually got better. Mokbanggi-tang treatment continued for 52 days and stopped on 58th day. After Mokbanggi-tang treatment ended, only Oryeongsan treatment was maintained. ■ Conclusion The present case report suggests that Korean-Western medicine approach with Mokbangki-tang and Oryeongsan might be effective to pleural effusion and heart failure symptoms such as poor physical activity shown in a NYHA Classification. This shows that Mokbanggi-tang and Oryeongsan can be a therapeutic option as a treatment for patient with Heart Failure with Preserved Ejection Fraction(HFpEF).

• Childhood Kidney Diseases
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• v.1 no.2
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• pp.189-194
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• 1997

Oligomeganephronia is a rare congenital form of bilateral renal hypoplasia histologically characterized by reduction in number and hypertrophy of nephrons. Clinically, this condition is presented in early infancy with vomiting, polyuria, polydipsia and dehydration. The problems are readily corrected, but slowly progressive renal failure follows accompanied by failure to thrive, short stature, and renal osteodystrophy. We experienced three cases of oligomeganephronia. Case 1. : A 3 2/12 years old female child was incidentally diagnosed as renal failure at age of 2 months when she was hospitalized due to pneumonia. She had open renal biopsy and was diagnosed as bilateral dysplastic kidney. On OPD follow-up, she progressed to end-stage renal failure (BUN/Cr 114/4.6 mg/dl) and had renal transplantation. The specimen was shrunk remarkably and light microscopy showed oligomeganephronia. Case 2. : A 14 8/12 years old female child with proteinuria was detected in an annual urine screening program for school children, she was diagnosed as renal failure (BUN/Cr 33.9/4.1 mg/dl), and had $5{\times}4{\times}3\;cm$ sized mass on abdominal CT scan. She had renal biopsy, and the specimen showed oligomeganephronia. She had hemodialysis for six months, and renal transplantation along with bilateral nephrectomy was performed. Case 3. : A 14 8/12 years old male child was diagnosed having chronic nephritis and chronic renal failure at 3 years old, progressed to end-stage renal failure (BUN/Cr 87/9.6 mg/dl) on OPD follow-up, and had a rephrectomy and renal transplantation. The biopsy specimen showed oligomeganephronic hypoplasia, secondary focal segmental glomerolosclerosis, and chronic interstitial nephritis. We report 3 cases of oligomeganephronia that progressed to end-stage renal failure and had successful renal transplantation with a brief review of related literatures.

• Journal of the Korean Geosynthetics Society
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• v.4 no.2
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• pp.47-56
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• 2005

Recently, geosynthetic reinforced earth walls are gradually replacing conventional concrete retaining walls for reasons of economy, expediency of construction, and aesthetics. A number of reinforced soil walls having more than 10m heights have been constructed to make more effective development in the country. However, mistakes in design and construction of reinforced earth walls have resulted in many troubles such as failure of reinforced earth walls, horizontal deformationor breakdown of facings, and so forth during or after construction. In this paper, a case study on global sliding failure of a geogrid-reinforced tiered wall is carried out to investigate the causes of the failure and suggest the proper countermeasures. From the subsurface investigation and field instrumentation, It is found that the cause of the global sliding failure was occurred by decreasing of bearing capacity of foundation ground induced by infiltration of rainwater.

• Journal of Chest Surgery
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• v.57 no.3
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• pp.315-318
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• 2024

The HeartWare Ventricular Assist Device (HVAD) was widely used for mechanical circulatory support in patients with end-stage heart failure. However, there have been reports of a critical issue with HVAD pumps failing to restart, or experiencing delays in restarting, after being stopped. This case report describes 2 instances of HVAD failure-to-restart during heart transplantation surgery and routine outpatient care. Despite multiple attempts to restart the pump using various controllers and extensions, the HVAD failed to restart, triggering a hazard alarm for pump stoppage. In one case, the patient survived after receiving a heart transplantation, while in the other, the patient died immediately following the controller exchange. These cases highlight the rare but life-threatening complication of HVAD failure-to-restart, underscoring the importance of awareness among clinicians, patients, and caregivers, and adherence to the manufacturer's guidelines and recommendations for HVAD management.

• Proceedings of the Korean Geotechical Society Conference
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• 2002.11b
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• pp.103-114
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• 2002

Stability of cut-slope is considered to have a deep relationship with rock types since rock has its own engineering and geological characteristic such as shear strength, durability, weathering profile, geological structures. Therefore, analysis of geological and engineering characterisics of rock mass is essential for the evaluation of rock slope stability This paper introduces the statistical data of slope failure cases which was collected from highway slopes constructed in sedimentary rock mainly of shale in Ky ng-sang Basin. Primary failure feature in this area is planar failure along the bedding regardless of slope geometry. Even a disasterous slope failure case due to the thick clay layer between the beddings was reported. Failures and rock fall were reported to ocurred frequently after the completion of cutting due to the weathering, so long-term slope stability should be considered as a important factors in design.

• Journal of Trauma and Injury
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• v.29 no.4
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• pp.191-194
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• 2016

Pseudo-renal failure presents with renal failure characteristics, such as hypercreatininemia and hyperkalemia without a change in glomerular filtration rate or structure of the kidney. Pseudo-renal failure due to trauma is difficult to diagnose, because symptoms are non-specific and other factors may cause hypercreatininemia and hyperkalemia. In a trauma patient, especially one with pelvic injury, the abrupt elevation of potassium, blood urea nitrogen, and creatinine levels without previous medical history is a key feature in the diagnosis of urinary ascites. We report a case of pseudo-renal failure caused by intraperitoneal bladder rupture in a multiple trauma patient.

• Proceedings of the Korea Concrete Institute Conference
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• 1998.04b
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• pp.585-591
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• 1998

In the case of reinforced concrete beams strengthening by steel plate, sometimes these beams collapse due to the stress concentration at the ends of steel plates before the design expected failure. This kind of failure is called premature failure. This study analyzes the behavior of strengthened RC beams to control premature failure of these plated beams with either changing the geometries at the ends of plates or strengthening steel plates beside the ends. The results from the former cases show that, the effect of expanded plates sections at the ends was very small, and the beams which are rounded the ends of plates effectively increased the initial rip-off loads about 14% compared with control beam but the ultimate loads was almost same. However, the beams in the latter cases effectively increased the initial and the ultimate rip-off loads with changing failure mode, especially around 14~19% in the ultimate rip-off load comparing with control beam.