• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1998년도 봄 학술발표회논문집(II)
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• pp.433-438
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• 1998

Design lateral strength calculated by current seismic design code is prescribed to be much lower than the force level required for a structure to respond elastically during design level earthquake ground motion. Present procedures for calculating seismic design forces are based on the use of elastic spectra reduced by a strength reduction factor known as "response modification factor, R". This factor accounts for the inherent ductility, overstrength, redundancy, and damping of a structural system. This study considers ductility and overstrength of the wall-type structure for investigating R factor. This means that R factor is determined from the product of "ductility-based R factor($R_$\mu$$) and overstrength factor($R_s$). $R_$\mu$$ factor is calibrated to attain the targer ductility ratio (system ductility capacity) and produced in the from of $R_$\mu$$ spectra considering the influence of target ductility, natural period, and hysteretic model. On the other hand, $R_s$ is more difficult to quantify, since it depends on both material and system-dependent uncertain parameters. In this study Rs factor was determined from the result of push-over analysis.-over analysis.

• 해양환경안전학회지
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• 제21권2호
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• pp.171-178
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• 2015

본 연구는 제한속력 설정 모델 개발을 위한 1차 연구로서 제한속력 설정 시 고려요소에는 어떤 것이 있으며, 각 요소별 중요도는 얼마나 되는지에 대한 연구의 결과이다. 고려요소 식별과 중요도 산정을 위해 델파이(Delphi)기법과 AHP(Analytic Hierarchy Process)기법을 이용하였다. 델파이 설문은 3차에 걸쳐 수행하였고 3차에 걸친 설문을 통해 5개 상위요소(Level 1)와 23개 하위요소(Level 2)가 식별되었다. 3차 델파이 설문과정에서 내용타당도비율(CVR)값이 0.4~1.0 범위에 있으면 제한속력 설정 시 고려요소로서 반영하였고 0.4 미만의 값은 고려요소에서 제외하였다. 2차 델파이 설문과정에서 33개 고려요소가 식별되었으나 3차 설문을 통해 23개 항목으로 축소되었다. 델파이 3차 분석을 통해 얻은 23개 항목을 대상으로 AHP 설문을 수행하였다. AHP 설문 결과, 5개 상위요소(Level 1)에 대한 중요도는 교통조건이 가장 중요한 요소로 평가되었고, 선박조건, 항로조건, 자연조건, 외부지원 및 기타 조건 순으로 평가되었다. 23개 하위요소 중에서 시정이 가장 중요(1위)하다고 평가되었으며, 선박조종성능, 항로 내 수중장애물, 교통량 및 밀도, 통항선박간 거리, 타효가능속력, 조류 순으로 평가되었다.

• 유통과학연구
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• 제22권3호
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• pp.105-112
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• 2024

Purpose: This study analyzed the relationship between corporate capacity and management performance in the Korean distribution industry during the COVID-19 pandemic. Research design, data and methodology: The data for this study used the 2021 KOTRA GCL Test Data, and multiple regression analysis was performed using SPSS 26. As corporate competency, human capital and related capital of intellectual capital theory were utilized, and the global network level of social network theory was also utilized. As an additional analysis, corporate characteristics factors were used. Results: First, the level of global mindset of human capital acted as a positive factor in management performance, and the level of professional manpower did not achieve significant results. Second, related capital acted as a positive factor in corporate performance. Third, from the perspective of social network theory, the global network level of companies acted as a positive factor in management performance. Finally, the relationship between corporate characteristics and management performance was marginally significant. Conclusions: In order to improve the business performance of a company in a market shock such as the COVID-19 pandemic, it is required to strengthen the level of network construction with customers and increase the level of intellectual capital that a company has.

• 한국유기농업학회지
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• 제18권3호
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• pp.315-329
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• 2010

This study focused on analysis of the satisfaction level of specialty shops for environment-friendly agricultural products (EFAP). To analyze the satisfaction level of EF AP, a series of household surveys were conducted. Questionnaire was prepared on the basis of the SERVQUAL model and the structural equation modeling was made on the basis of the contents surveyed. The main results of this study are summarized as follows. Firstly, tangibles structured with store clearance, neat uniform, information and others is the factor of service quality satisfaction. Secondly, reliability structured with service practice, problem solving, and service in accurate time is the factor of service quality satisfaction. Thirdly, assurance structured with the reliability of employees, sufficient knowledge of employees, courteous and good manner is the factor of service quality satisfaction. Fourthly, responsiveness structured with prompt service, voluntary help, customer response service and the like is the factor of service quality satisfaction. Fifthly, the sympathy structured in interest for each customer, provision of service in time convenient to use, encountering the customers with genuine feeling are the factors of service quality satisfaction. And sixthly, the service satisfaction factors would influence on the consumer behavior factors.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7831-7834
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• 2014

Objective: To explore the influence of different ways of blood transfusion on the expression levels of interleukins (IL) and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) inperi-operative patients with esophageal cancer. Materials and Methods: A total of 80 patients with esophageal cancer who underwent radical operations were selected as study patients and randomly divided into an observation group (treated with autologous blood transfusion) and control group (with homologous blood transfusion). Changes of intra-operative indexes and peri-operative blood indexes, from hemoglobin (Hb) and hematocrit value (Hct), to levels of inflammatory factors like interleukins-6 (IL-6), IL-8, IL-10 and tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) were compared. Results: Operations for patients in both groups were successfully conducted, and no significant differences in mean surgical duration and intra-operative hemorrhage volume, fluid infusion volume and blood transfusion volume were detected (p>0.05). Compared with values before surgery, Hb and Hct levels decreased significantly while white blood cell count (WBC) increased 1, 5 and 7 d after operation (p<0.05, p<0.01). In addition, WBC was apparently higher in observation group than in control group 5 and 7 d after operation (p<0.01). Compared with before surgery, in the observation group, levels of IL-6, IL-8 and IL-10 had no significant differences after operation (P>0.05), but TNF-${\alpha}$ level increased y (p<0.01), whereas in control group, IL-6 level had no significant difference (p>0.05), IL-8 level decreased obviously (p<0.05), IL-10 level increased markedly first and then decreased gradually as time passed but its level remained elevated (p<0.01), and TNF-${\alpha}$ level increased first and then decreased, and there was no significant difference 7 d after operation (p>0.05). Conclusions: Decreased IL-8 and increased IL-10 levels are two important reasons for immunosuppression after homologous blood transfusion, whereas autologous blood transfusion can alleviate this while increasing the TNF-${\alpha}$ level, which also has potential to improve anti-tumor immunity in the human body.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1996년도 추계학술대회
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• pp.372-376
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• 1996

This paper describes the criterias to evaluate arousal states of subject and these are applied to contort arousal level. Correction factor was introdued to compensate under or over evaluated Nz due to the different initial basal skin impedance. These criteria and correction factor were worked well to increase the arousal level.

• Journal of Microbiology
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• 제38권3호
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• pp.160-168
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• 2000

A-factor I a microbial hormone that can positively control cell differentiation leading to spore formation and secondary metabolite formation in Streptomyces griseus. to identify a protease that is deeply involved in the morphological and physiological differentiation of Streptomyces, the proteases produced by Streptomyces griseus IFO 13350 and its A-factor deficient mutant strain, Streptomyces griseus HH1, as well as Streptomyces griseus HH1 transformed with the afsA gene were sturdied. In general Streptomyces griseus showed a higher degree of cell growth and protease activity in proportion to its ability to produce a higher amount of A-factor. In particular, the specific activity of the trypsin of Streptomyces griseus IFO 13350 was greatly enhanced more than twice compared with that of Streptomyces griseus HH1 in the later stage of growth. The specific activity of the metalloprotease of Streptomyces griseus HH1 was greatly enhanced more than twice compared with that of Streptomyces griseus IFO 13350, and this observation was reversed in the presence of thiostreptione, However, Streptomyces griseus HH1 transformed with the afsA gene showed a significantly decreased level of trypsin and metalloprotease activity compared with that of the HH1 strain. There was no significant difference between Streptomyces griseus IFO 13350 and HH1 strain in their chymotrypsin and thiol protease activity, yet the level of leu-amionpeptidase activity was 2 times higher in Streptomyces griseus HH1 than in strain IFO 13350 . Streptomyces griseus HH1 harboring afsA showed a similar level of enzyme activity , however, all the three protease activities sharply increased and the thiol protease activity was critically increased at the end of the fermentation. When a serine protease inhibitor, pefabloc SC, and metalloprotease inhibitor, EDTA, were applied to strain IFO 13350 to examine the in vivo effects of the protease inhibitors on the morpholofical differentiation, the formation of aerial meycelium and spores was delayed by two or three days.

• 한국전통조경학회지
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• 제28권4호
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• pp.105-111
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• 2010

본 연구는 앞으로의 조경계획 및 디자인을 개선하기 위해 서안명성곽공원의 시각적 선호 이미지 요인과 성곽과 해자의 조화 정도를 파악하여 중국 도시공원 및 역사공원 설계 시 기초자료를 제시하는 것이 목적이다. 이 연구는 문헌 조사와 현장 조사를 통해 이루어졌다. 문헌조사는 서안명성곽 및 명성곽공원의 관련 자료들을 수집하였으며, 현장 조사는 현장관찰과 서안명성곽공원 이용에 관한 설문 조사를 통해 이루어졌다. 설문을 통해 얻어진 데이터는 사회 과학 통계 분석 프로그램(SPSS17.0 for Windows)을 이용하여 분석하였다. 설문을 통해 얻어진 데이터를 주성분 요인분석을 실시하여 3가지 요인이 추출됐다. 추출된 3가지 요인인 환경인자, 편리인자, 문화심미인자의 변수에 대해서 다중회귀분석을 실시하였다. 전체 만족도에 가장 큰 영향을 준 요인은 환경인자로 나타났다. 14가지 조경요소 중에 포장, 원림건축, 입구공간 등 3개 요소가 성곽과 조화정도에 큰 영향을 주고 있었고, 휴식공간, 수경, 포장 등 3개 요소가 해자와 조화정도에게 큰 영향을 주고 있으므로 나타났다.

• Reproductive and Developmental Biology
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• 제36권1호
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• pp.13-19
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• 2012

In order to provide the basis for developing practical mouse embryonic stem cells (mESCs) culture method, how the endogenous level of self-renewal-stimulating factor genes was altered in the mESCs by different extracellular signaling was investigated in this study. For different extracellular signaling, mESCs were cultured in 2 dimension (D), 3D and integrin-stimulating 3D culture system in the presence or absence of leukemia inhibitory factor (LIF) and transcriptional level of $Lif$, $Bmp4$ and $Wnt3a$ was evaluated in the mESCs cultured in each system. The expression of three genes was significantly increased in 3D system relative to 2D system under LIF-containing condition, while only $Wnt3a$ expression was increased by 3D culture under LIF-free condition. Stimulation of integrin signaling in mESCs within 3D system with exogenous LIF significantly up-regulated transcriptional level of $Bmp4$, but did not induce transcriptional regulation of $Lif$ and $Wnt3a$. In the absence of LIF inside 3D system, the expression of $Lif$ and $Bmp4$ was significantly increased by integrin signaling, while it significantly decreased $Wnt3a$ expression. Finally, the signal from exogenous LIF significantly caused increased expression of $Lif$ in 2D system, decreased expression of $Bmp4$ in both 2D and 3D system, and decreased expression of $Wnt3a$ in integrin-stimulating 3D system. From these results, we identified that endogenous expression level of self-renewal-stimulating factor genes in mESCs could be effectively regulated through artificial and proper manipulation of extracellular signaling. Moreover, synthetic 3D niche stimulating endogenous secretion of self-renewal-stimulating factors will be able to help develop growth factor-free maintenance system of mESCs.

• 한국항공운항학회지
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• 제25권2호
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• pp.12-17
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• 2017

Manned aircraft structural design is based on structural safety factor of 1.5, and this safety factor is equivalent to a probability of failure of between 10-2 and 10-3. The target failure probability of FARs is between 10-6 and 10-9 per flight according to aircraft type. NATO released STANAG 4703 to established the airworthiness requirements for small UAV which is less than 150kg. STANAG 4703 requires the Target Level of Safety according to MTOW. The requirements of failure probability for small UAV is between 10-4 and 10-5. In this paper, requirements of airworthiness certification for small UAV were investigated and the relationship of safety factors to the probability of structural failure is analyzed to reduce measure of safety factor and structural weight of unmanned aircraft.