• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1053-1055
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• 2016

Background: Polycythemia rubra vera (PV), being a primary polycythemia, is caused by neoplastic proliferation of erythroid, megakaryocytic and granulocytic lineages which result in panmyelosis. PV patients have a somatic acquired mutation in the Janus kinase (JAK2) pathway, rendering cell proliferation independent of the normal regulatory mechanisms that regulate erythropoiesis. The rational of this study was to determine the prevalence of the JAK-2 V617F mutation in Pakistani patients with PV. Materials and Methods: In this cross sectional study, 26 patients with PV were enrolled from January 2010 to December 2014. Patients were diagnosed based on WHO criteria for PV. All were screened for G-T point mutation (V617F) in the JAK2 gene on chromosome 9 by an allele specific PCR. Results: The mean age was $53.4{\pm}9.31years$ (range 36-72) and the male to female ratio was 2:1. The frequency of JAK2 V617F positivity in our PV patients was found to be 92.3%. Overall 30.7% of patients were asymptomatic and remaining 69.3% presented with symptomatic disease. The mean hemoglobin was $18.1{\pm}1.9g/dl$ with the mean hematocrit of $55.6{\pm}8.3%$. The mean total leukocyte count was $12.8{\pm}7.1{\times}10^9/l$ and the platelet count was $511{\pm}341.9{\times}10^9/l$. A positive correlation of JAK2 V617F mutation was established with high TLC count (P=0.01). No correlation of JAK2 V617F could be established with age or gender (P>0.05). Conclusions: The JAK2 V617F mutation frequency in our PV patients was similar to those reported internationally. Screening for the mutation in all suspected PV cases could be beneficial in differentiating patients with reactive and clonal erythrocytosis.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송∙미디어공학회 2020년도 추계학술대회
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• pp.166-168
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• 2020

MPEG 비디오 그룹은 MPEG-I 표준의 일부로 포인트 클라우드(Point Cloud) 압축을 위한 비디오 기반 포인트 클라우드 부호화(V-PCC)와 몰입형(immersive) 비디오 압축을 위한 MPEG Immersive Video(MIV) 표준을 개발하고 있다. 최근에는 포인트 클라우드 및 몰입형 비디오와 같은 체적형(volumetric) 비디오를 모두 압축할 수 있도록 V-PCC 와 MIV 를 통합한 V3C(Visual Volumetric Video-based Coding) 표준화를 진행하고 있다. 본 논문에서는 V3C 코덱을 사용한 3DoF+(3 Degree of Freedom plus) 비디오 부호화 방안을 분석한다. 또한 V3C 코덱의 2D 코덱으로 기존 HEVC 대신 VVC 를 사용할 경우의 부호화 성능 향상을 분석한다.

• 전기전자학회논문지
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• 제28권1호
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• pp.110-115
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• 2024

본 논문은 3D NAND Flash memory에서 tapering된 O/N/O(Oxide/Nitride/Oxide) 구조와 blocking oxide를 ferroelectric material로 대체한 O/N/F(Oxide/Nitride/Ferroelectric) 구조의 V_th(Threshold Voltage) 변화량을 분석했다. Tapering 각도가 0°일 때 O/N/F 구조는 O/N/O 구조보다 저항이 작고 WL(Word-Line) 상부와 WL 하부의 V_th 변화량이 감소한다. Tapering된 3D NAND Flash memory는 WL 상부에서 WL 하부로 내려갈수록 channel 면적이 감소하며 channel 저항이 증가한다. 따라서 tapering 각도가 증가할수록 WL 상부의 V_th가 감소하고 WL 하부의 V_th는 증가한다. Tapering된 O/N/F 구조는 channel 반지름 길이와 비례하는 V_fe로 인해 WL 상부의 V_th는 O/N/O 구조보다 더 감소한다. 또한 O/N/F 구조의 WL 하부는 O/N/O 구조보다 V_th가 증가하기 때문에 tapering 각도에 따른 V_th 변화량이 O/N/O 구조보다 더 증가한다.

• Journal of Advanced Marine Engineering and Technology
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• 제35권5호
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• pp.616-624
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• 2011

본 연구에서는 사각채널내에 주유속 방향에 가로지르게 배치된 반원 리브의 난류 유동에 대한 유동 특성과 열전달 증대에 관해 수치해석적으로 살펴보았다. 사각채널의 종횡비는 5이고, 수력직경 대비 리브 높이비는 0.07, 사각채널 높이 대비 리브 높이비는 0.117로서 리브 높이 대비 리브 피치비가 8~14인 리브를 주기적으로 배열하여 연구를 수행하였다. 난류 모델의 선정은 실제 현상과 근접한 벽 근처 유동 특성과 열전달을 위해 SST k-${\omega}$ 난류 모델과 v2-f 난류 모델을 이용하였다. 수치해석의 결과는 실험에 의 해 관찰된 난류 유동 특성, 열전달 및 마찰계수의 결과를 잘 예측함을 보여준다. 본 결과에서 난류 운동 에너지가 재순환류 영역의 확산과 밀접한 관련이 있음을 알 수 있고 v2-f 난류 모델이 SST k-${\omega}$ 난류 모델에 비해 실험결과를 더 잘 예측하였다.

• 한국정밀공학회지
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• 제13권12호
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• pp.70-77
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• 1996

Fatigue tests were carried out at high temperature on a Cr-Mo-V steel in order to assess the fatigue life of components used in power plants. The characteristics of high temperature fatigue were divided in terms of cycle-dependent fatigue and time-dependent fatigue, each crack propagation rate was examined with respect to fatigue J-integral range, .DELTA. J$_{f}$and creep J-integral range, .DELTA. J$_{c}$. The fatigue life was evaluated by analysis of J-integral value at the crack tip with a dimensional finite element method. The results obtained from the present study are summarized as follows : The propagation characteristics of high temperature fatigue cracks are determined by .DELTA. J$_{f}$for the PP(tensile plasticity-compressive plasticity deformation) and PC(tensile plasticity - compressive creep deformation) stress waveform types, and by .DELTA. J$_{c}$for the CP(tensile creep- compressive plasticity deformation) stress waveform type. The crack propagation law of high temperature fatigue is obtained by analysis of J-integral value at the crack tip using the finite element method and applied to examine crack propagation behavior. The fatigue life is evaluated using the results of analysis by the finite element method. The predicted life and the actual life are close, within a factor of 2.f 2.f 2.

• 한국소음진동공학회논문집
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• 제14권6호
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• pp.470-477
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• 2004

This study shows the design process of a MR damper for semi-active suspension systems. Damping force characteristics of the designed damper was predicted through the flow analysis and magnetic analysis. The predicted results were compared with the experimental results and the initial design specification was modified according to the results.

• 한국음향학회지
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• 제30권4호
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• pp.231-237
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• 2011

본 연구에서는 실험음성학적 분석을 통해 선호감각유형과 발화속도 및 기본주파수 (이하, $F_0$)와의 상관성을 연구하였다. 대학생 및 대학원생 36명 (남학생 17명, 여학생 19명)을 대상으로 선호감각유형검사를 실시하였고, 읽기와 그림보고 말하기 과제, 그리고 대화과제를 실시하여 말속도를 측정하였고, 일상대화시의 $F_0$와 말속도를 측정하였다. 연구 결과, D (내부언어) 유형을 제외했을 때 V (시각) 유형의 경우 읽기과제에서 말속도와 상관성이 있었고, D (내부언어) 유형을 포함했을 때 A (청각) 유형과 F0에서 상관성이 있었다. 또한 VAK (시각, 청각, 촉각) 유형의 평균을 분석한 결과 말속도의 경우 인터뷰 과제를 제외한 나머지에서, VAKD (시각, 청각, 촉각, 내부언어) 유형의 평균에서는 전체 과제에서 V (시각) 유형이 A (청각) 유형보다 발화속도가 빠르고 $F_0$가 높았음을 확인할 수 있었다. 이 연구결과에서 선호감각유형과 $F_0$와 말속도가 상관성이 있음을 알 수 있었다. 본 연구는 인문치료 진단 및 평가에서 주관적 감각유형검사와 함께 말소리의 객관적 분석을 통하여 감각유형검사의 보완적 역할이 가능하고, 이를 통해 맞춤형 교육 및 상담에서 유용하게 활용이 될 수 있을 것이다. 또한, 선호감각유형과 발화속도 및 $F_0$의 상관성에 관한 연구의 기초토대를 마련하였다.

• 한국결정성장학회:학술대회논문집
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• 한국결정성장학회 1998년도 PROCEEDINGS OF THE 14TH KACG TECHNICAL MEETING AND THE 5TH KOREA-JAPAN EMGS (ELECTRONIC MATERIALS GROWTH SYMPOSIUM)
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• pp.145-148
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• 1998

Fluoride({{{{ { CaF}_{2 } }}}}) films exhibited a cubic structure with similar lattice constant to that of Si and have sufficient breakdown electric field as gate dielectric material. Therefore, {{{{ { CaF}_{2 } }}}} are expected to replace conventional insulator such {{{{ { SiO}_{ 2},{Ta}_{2}{O}_{ 2} and{Al}_{2}{O}_{5}. However, {CaF}_{2}}}}} films showed hystereisis properties due to mobile charges in the film. To solve this problem we performed thermal treatment and achieves field. C-v results indicate a reduced hystereisis window of {{{{ }}}}ΔV =0.2v, LOW INTERFACE STATE {{{{{D}_{it}=2.0 TIMES {10}^{11}{cm}^{-1}{eV}^{-1}}}}} in midgap, and good WIS diode properties. We observed a preferential crystallization of(200) plane from XRD analysis. RTA treatment effects on various material properties of {{{{{CaF}_{2}}}}} are presented in this paper.

• 품질경영학회지
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• 제51권4호
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• pp.481-496
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• 2023

Purpose: The main theme of this study is to derive a profit curve by a cubic cost function for nonlinear CVP analysis. According to the analytical approach to derive a nonlinear profit function in this study, it is possible with only the existing cost structure to calculate the profit maximization and downtime point sales unlike the classical CVP analysis. Furthermore, the profit curve by the mathematical model of this study could serve as a tool to quantify the qualitative evaluation of each stage of the industry life cycle. Methods: This study followed the mathematical approach from the cubic cost function model of microeconomics, and using real data of the Bank of Korea Results: The nonlinear profit function suggested by this study is as follows; ${\pi}(x)=-a\left(x-\frac{f}{1-v}\right)^3+(1-v)x-k$ where $a=\frac{1}{3}v\left(\frac{(1-v)}{f}\right)^2,k=f-a\left(1-\frac{f}{1-v \right)^3$ Conclusion: The process and results of this study would be able to contribute not only in practice of nonlinear CVP analysis required in the management accounting or financial management, but also in cost theory of microeconomics. Also, since the life cycle of all industries in Korea was verified to the growth or mature stage, decision makers should pay careful attention to determining life cycle stages and consider the profit curve by the average variable cost ratio over multi periods.

• 한국전산유체공학회지
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• 제10권4호통권31호
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• pp.1-11
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• 2005

A numerical study of the evaluation of turbulence models for thermal striping phenomenon is performed. The turbulence models chosen in the present study are the two-layer model, the shear stress transport (SST) model and the V2-f model. These three models are applied to the analysis of the triple-jet flow with the same velocity but different temperatures. The unsteady Reynolds-averaged Navier-Stokes (URANS) equation method is used together with the SIMPLEC algorithm. The results of the present study show that the temporal oscillation of temperature is predicted by the SST and V2-f models, and the accuracy of the mean velocity, the turbulent shear stress and the mean temperature is a little dependent on the turbulence model used. In addition, it is shown that both the two-layer and SST models have nearly the same capability predicting the thermal striping, and the amplitude of the temperature fluctuation is predicted best by the V2-f model.