• Journal of Pharmaceutical Investigation
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• 제22권3호spc1호
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• pp.35-47
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• 1992

Hydrogel coated ring shaped ocular inserts (containing the antibiotic, tylosin tartrate) were used in an evaluation of the effectiveness of polymeric ocular drug release devices for treating infectious bovine keratoconjunctivitis. The in vivo experiments represent the first experiments using hydrogel ocular inserts containing an antibiotic for treating infectious bovine keratoconjunctivitis. In the infection tests, ten calves. were challenged with $2.4{\times}10^8{\sim}1.6{\times}10^9$ Moraxella bovis (a bacterium) colonies per eye following two ten minute ultraviolet radiation eye preconditioning exposures. Ninety five percent of the eyes (19 of 20 eyes) were successfully infected by this method. All infected eyes were monitored for the presence of the bacteria quantitiatively, and clinical observations were made for 14 days. The test was performed by three consecutive steps: 1) inoculation with 2 ultraviolet (UV) radiations, 2) growth of bacterial colonies and 3) treatment with medicated ring-shaped devices. The first. bacteriological measurements after 2 UV exposures were performed at day 3 of the tests. At day 7 after inoculation of both eyes of a calf with M. bovis, a medicated or a non-medicated ring-shaped device was inserted into each eye of a calf. The eye receiving the non-medicated ring was taken as a control for comparison with the eye that received a medicated ring. During the next 7 day period following a medicated ring insertion, the number of bacteria in the treated eyes dropped dramatically to negligible levels (0 to 30 colony forming units/swab), while the control eyes which received a non-medicated ring still exhibited a relatively high number of bacteria ($10^3\;to\;10^6$ colony forming units/swab). The number of bacteria was significantly reduced by the antibiotic released from the medicated ocular insert.

• 한국염색가공학회지
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• 제25권1호
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• pp.65-69
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• 2013

PET fabrics of various luster, fiber thickness(denier), and weaving structure were dyed at the same conditions and determined their grey scale by using naked eyes, computer color matching (CCM) system, and real industry color (RIC) device to evaluate the effectiveness of RIC device developed in this study. As for the luster of fabrics, bright PET showed more differences when compared with semi-dull and full-dull. PET in both naked eyes and RIC device since the RIC device provide the real image of fabrics to observers. As for the fiber thickness, the results of naked eyes and RIC device were very similar while the result of CCM showed lower color grade. Finally, as for the weaving structures of PET fabrics, all the test results by naked eyes, CCM, and RIC device showed almost same grey scales. In these regards, the RIC device developed in this study was comparable to naked eyes by providing the real image of fabrics, however it was difficult to compare the very bright colors such as yellow and fiber thickness(denier) and weaving structure of fabrics.

• 대한한의진단학회지
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• 제12권2호
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• pp.49-60
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• 2008

Objectives: The aim of this study was to investigate correlation of the phlegm-retained fluid, namely Damum(痰飮) and dark circles under eyes. Methods: 2 males and 11 females aged 26-60 years were participated in this study. They were asked the intensity of 29 symptoms related with Damum(痰飮) including dark circle with the questionnaire published by the Journal of the Korea Institute of Oriental Medical Diagnostics. Three skin researchers including OMD graded the dark circles by inspection. We took the pictures around eyes by Facial Stage (Moritex, Japan) and analyzed the skin color by Image-Pro Plus (Media Cybernetics, USA). Results: There was statistically significant correlation between Damum(痰飮) and dark circles measured by self, inspectors and image analysis. Conclusions: In the Oriental Medicine, It is reported that the shadows under eyes are the sign of the retention of fluid, Damum(痰飮). In our study, that shadows, namely dark circles, has correlation with the symptoms of Damum(痰飮). Especially, the correlation between inspected grade and image analysis was very high. According to the above results, it is proved that dark circles under eyes are important diagnostic sign of Damum(痰飮).

• 한국응용곤충학회지
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• 제34권4호
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• pp.334-343
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• 1995

명상태와 암상태에서 벼멸구의 겹눈의 미세구조가 변화하는 것을 관찰하였다. 벼멸구의 겹눈을 암조건 혹은 광조건 하에서 최고 72시간 까지 유지하였을 경우에 비슷한 수준에서 겹눈을 절단하여 해부 현미경으로 관찰한 결고, 구조적인 면에서 서로 다른 모양을 관찰하였다. 한편, 전자현미경을 이용하여 암조건과 광조건 하에서의 겹눈의 미세구조를 비교한 결과, 단애층(palisade layer)의 넓이는 광조건하에서 암조건에서 보다 더 좁은 것을 알 수 있었다. 색소체는 암적응 상태의 눈에서는 단애층 주위에 원을 형성하고 있었지만, 감간채 주위에 밀집되어 있지는 않았다. 암적용과 광적용 상태의 눈에 있는 망막세포 내에서의 미세융모 지름은 차이가 없었으며, 수정체와 감간체의 접합 부위에 있는 색소체의 이동은 감간체의 위부분에 있은 수정체의 끝부분에서 변화가 있음을 관찰 할 수 있었다.

• 한국실내디자인학회논문집
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• 제23권1호
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• pp.122-131
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• 2014

This study aimed to conduct an eye-tracking experiment carried with facade images as a medium and to do research on 'the interest of the eyes' resulted from people's gazing phenomena. This study secured gazing data which appeared according to visual response and analyzed gazing phenomena to find the basic theory of 'the interest of the eyes' as a methodological role, which consumer interest and attention could be grafted when a plan and a design for space design was made. Data terms used in eye-tracking backgrounds and the movement of the eyes were investigated in literature review. Twenty (20) facade images were selected through a case study to get experimental stimuli for the related experiment. Thirty (30) subjects (men and women) suitable for the experiment were recruited to conduct an eye-tracking experiment. After the experiment, five (5) areas were set up in the facade image to identify the focus level of interest and attention. The level of interest and focus was connected to the interest of the eyes. The analysis to study the interest of the eyes was based on nine (9) items such as sequence, entry time, dwell time, hit ratio, revisits, revisitors, average fixation, first fixation and fixation count. Through gaze analysis, the following conclusion was drawn about the 'interest level of sight' for gaze frequency. The interest level can be interpreted to be higher for faster sequence, shorter entry time, longer all fixation(ms) for dwell time, faster all saccade(%), higher hit ratio, more revisits, more revisitors, longer average fixation, faster and longer first fixation, and more fixation count, and the person can be said to have felt interest faster and/or more.

• The Journal of Korean Physical Therapy
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• 제16권1호
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• pp.208-246
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• 2004

The purpose of this study was to investigate the effect of aqua exercise program on the static balance of child with mental retardation. The subjects were seven male child and three female child with mental retardation(age ranges from 5 to 6). The subjects were practiced with focusing on the aqua exercise program for 8 weeks, from 7, January 2003 to 28, February 2003. The results of this study were as follows : 1. After the exercise program, the balance of double-stance by BPM was significantly reduced of lateral sway number by $12.2\%$(P<.01) with eyes obstruct. 2. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of left leg by $8.5\%$(P<.05) with eyes obstruct. 3. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of right leg by $8.3\%$(P<.05) with eyes obstruct. 4. After the exercise program, the balance of double-stance by BPM was significantly reduced of lateral sway number by $13.2\%$(P<.01) with eyes open. 5. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of left leg by $10.3\%$(P<.05) with eyes open. 6. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of right leg by $10.3\%$(P<.01) with eyes open. As we can see the results of this study, the aqua exercise program improved the static balance of child with mental retardation. Futhermore, it is reasonable program that can improvability of static balance for the children with mental retardation using aqua exercise program. And then it is necessary to develop much better program than now for the children with mental retardation's health and to provide the adequate pool for their aqua exercise.

• 대한수의학회지
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• 제62권3호
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• pp.26.1-26.7
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• 2022

This study was aimed to evaluate the prophylactic anti-glaucoma effect of topical 5% betaxolol (BTX) and 2% dorzolamide (DRZ) on the second eye in dogs with unilateral primary angle closure glaucoma (PACG). Medical records of 60 dogs with unilateral PACG who received prophylactic anti-glaucoma eyedrops in the second eye, from 2016 to 2021, were reviewed. The prophylactic effects of BTX were maintained on 28/60 (46.7%) eyes until last visit and BTX failure was observed on median 510 (range, 53-1,927) days in 32/60 (53.3%) eyes. After DRZ instillation in BTX failure eyes, the prophylactic effects were extended at median 610 (range, 157-2,270) days in 21/32 (65.6%) eyes. DRZ failure eyes (17/21, 81.0%) eyes required chemical ablation or surgical intervention due to uncontrolled intraocular pressure. The duration of prophylactic effects was decreased with aging (R² = 0.334, p = 0.006). The predominant breeds were Shih-Tzu (41.9%) and American Cocker Spaniel (30.6%) with no significant differences in survival curves (p = 0.210). The average prophylactic effects of BTX persisted more than 1.5 year and could be selected the first prophylactic eye drop in unilateral PACG. Also, early surgical intervention should be considered in prophylactic medications failure cases.

• Journal of Yeungnam Medical Science
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• 제11권1호
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• pp.55-62
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• 1994

녹내장 누공수술의 대표적 수술인 섬유주절제술의 주된 실패요인인 여과포의 섬유화를 막아 수술성공율을 향상시키기 위해 항대사 물질인 Mitomycin C를 수술실패 위험이 높은 녹내장 환자 20명 25안을 대상으로 섬유주절제술중에 사용하여 섬유주절제술의 보조제로서의 Mitomycin C의 효과를 알아보았다. 전체 대상안의 수술전 평균 안압은 $38.6{\pm}6.6mmHg$였으며 수술 후 최종 평균안압은 $11.7{\pm}3.8mmHg$로 26.9mmHg의 안압감소를 나타내었다. 수술 성공율은 40세 이하의 원발광우각녹내장에서는 8안중 7안 (88%), 포도막염에 의한 속발 녹내장에서는 6안중 5안(83%), 신생혈관녹내장에서는 5안중 4안(80%)에서 성공하였고 유년녹내장과 과거 수술 기왕력이 있는 녹내장 및 무수정체녹내장에서는 6안 모두 (100%)에서 성공함으로서 전체적으로는 25안중 22안에서 성공하여 88%의 성공율을 나타내었다. 수술 후 시력 변화는 25안중 24안(96%)에서 수술전 시력에 비해 변함이 없거나 다소 호전되었으며 1안(4%)에서 시력 소실을 보였다. 술후 합병증은 전방출혈이 5안(20%), 얕은 전방이 4안(16%), 저안압증이 4안(16%), 점상각막염이 3안(12%), 결막봉합파열이 2안(8%), 낭포화된 여과포가 1안(4%), 맥락막 박리 1안(4%)에서 발생하였다. 결론적으로 섬유주절제술에서 Mitomycin C의 부가적 사용은 수술 실패 위험이 높은 녹내장에서 효과적이고 비교적 안전하게 사용할 수 있으나 장기간 경과 관찰을 통하여 안전하고 효과적인 사용법에 대한 다양한 연구가 필요할 것으로 사료된다.

• 만화애니메이션 연구
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• 통권41호
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• pp.429-454
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• 2015

본 논의의 출발점은 '자신을 본다'는 거울의 시선에 있다. 거울은 시각을 연장하고 자신이 가질 수 없는 상들을 제공하면서, 닮음, 재현, 반성, 실재 등에 대한 여러 의문을 제기하며 자의식을 강화하는 등 수세기 동안 그 의미는 재인식되어 왔다. 이처럼 거울을 본다는 것은 자기상의 또 다른 표면적 존재를 낳아, 거울 자체의 양면성이라는 실체와 허상 간의 모호한 간격으로 인해 지속적인 관심의 대상이다. 오늘날 거울의 반사상에 대한 과도한 열중은 더욱 심화되어 표출된다. 복잡한 이중적인 구조로 채워진 거울의 시선은 보는 자와 보이는 자의 관계로, 주체와 대상, 대상과 주체와의 불분명한 경계를 낳으며, 타인의 시선으로부터 존재하는 모든 국면들과 마주하며 교차적인 세계의 가능성을 열어준다. 더욱이 거울의 반사적 의미는 회화와 문학을 비롯한 여러 가지 미적 표현양식에 다양한 시선으로 떠오르는 모호한 수수께끼의 매체로서, 작가들에게 적지 않게 반영되며 창조적인 담론을 낳았다. 이에 본고에서는 거울의 시선이 세계의 상황 속에 서있는 이중의 영역에 반영된 불투명한 인간의 시선임을 제시하며, 보다 구체적인 접근을 위해 거울의 역사적 흐름을 전개하여 문학, 예술 작품에 투영된 일련의 사례들을 통해 닮음의 반사적 구조를 드러낼 것이다. 이 과정은 보는 자와 보이는 자의 관계, 즉 지각하는 주체와 거울에 반영된 타자의 시선임을 모색해봄으로써, 나와 세계가 상호 얽힘의 교차관계 속에서 자신의 삶이 존재하고 있음을 반추해보는 계기가 될 것이다.

• 한국컴퓨터정보학회논문지
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• 제27권12호
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• pp.259-266
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• 2022

본 연구는 생활습관관리를 통하여 구강건조와 안구건조를 예방하여 통합적인 건강증진교육을 위한 기초자료를 마련하고자 한다. 2022년 10월 7일부터 17일까지 전국에 있는 20대 대학생들을 대상으로 자기기입방식의 구조화된 설문지를 통해 자발적으로 동의 후 응답한 전체 516명의 설문결과를 통계분석 하였다. 연구대상자의 생활습관 중 구강건조를 느끼게 하는 영향 요인으로는 하루 흡연량이 많을수록 구강건조를 높게(8.41±2.041), 매우 높게(7.75±2.927) 느끼는 것으로 나타났으며(p=.015), 스마트폰 사용 시간이 짧을수록 구강건조를 낮게(1.16±0.784), 매우 낮게(1.83±1.672) 느끼는 것으로 나타났다(p=.022). 구강건조와 안구건조를 느끼게하는 주요 요인으로는 구강건조를 느낄 때 안구건조를 3.651배 높게 느끼며(p=.000), 생활습관에서는 흡연량이 많아질 수록 0.916배 높게 느끼고(p=.038), 스마트폰 사용시간이 길수록 구강건조를 1.292배 높게 느낀다(p=.004). 안구건조가 있을 때 구강건조를 4.002배 높게 느끼며(p=.000), 운동의 시간이 많을수록 안구건조를 1.600배(p=.009) 느낀다. 결과적으로, 구강건조와 안구건조는 공통의 불편요인으로 나타나므로 건강생활의 유지·증진을 위하여 생활습관관리가 필요한 것으로 사료된다. 따라서 삶의 질을 향상할 수 있는 통합건강증진플랫폼이 구축되어 개인의 맞춤 건강관리 프로그램 시행이 이루어지도록 제안한다.