• Title/Summary/Keyword: exposure sources

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Polycyclic Aromatic Hydrocarbons (PAHs) and their Bioaccessibility in Meat: a Tool for Assessing Human Cancer Risk

  • Hamidi, Elliyana Nadia;Hajeb, Parvaneh;Selamat, Jinap;Razis, Ahmad Faizal Abdull
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.1
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    • pp.15-23
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    • 2016
  • Polycyclic aromatic hydrocarbons (PAHs) are primarily formed as a result of thermal treatment of food, especially barbecuing or grilling. Contamination by PAHs is due to generation by direct pyrolysis of food nutrients and deposition from smoke produced through incomplete combustion of thermal agents. PAHs are ubiquitous compounds, well-known to be carcinogenic, which can reach the food in different ways. As an important human exposure pathway of contaminants, dietary intake of PAHs is of increasing concern for assessing cancer risk in the human body. In addition, the risks associated with consumption of barbecued meat may increase if consumers use cooking practices that enhance the concentrations of contaminants and their bioaccessibility. Since total PAHs always overestimate the actual amount that is available for absorption by the body, bioaccessibility of PAHs is to be preferred. Bioaccessibility of PAHs in food is the fraction of PAHs mobilized from food matrices during gastrointestinal digestion. An in vitro human digestion model was chosen for assessing the bioaccessibility of PAHs in food as it offers a simple, rapid, low cost alternative to human and animal studies; providing insights which may not be achievable in in vivo studies. Thus, this review aimed not only to provide an overview of general aspects of PAHs such as the formation, carcinogenicity, sources, occurrence, and factors affecting PAH concentrations, but also to enhance understanding of bioaccessibility assessment using an in vitro digestion model.

Exploratory Study on Countering Internet Hate Speech : Focusing on Case Study of Exposure to Internet Hate Speech and Experts' in-depth Interview (인터넷 혐오표현 대응방안에 관한 탐색적 연구 : 노출경험 사례 및 전문가 심층인터뷰 분석을 중심으로)

  • Kim, Kyung-Hee;Cho, Youn-Ha;Bae, Jin-Ah
    • The Journal of the Korea Contents Association
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    • v.20 no.2
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    • pp.499-510
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    • 2020
  • This study aims to analyze the causes of Internet hate speech, which has recently been emerging as a serious social problem and to seek for countermeasures. The experiences of hate speech are examined through the analysis of college students' essays and the causes and solutions of hate speech are suggested through the in-depth interviews with the experts. College students experience hate speech on the Internet on the basis of attributes such as age, gender, sexual orientation, and regionalism. Online comments on news, social media and online games are the main sources in spreading hate speech. On a personal level the lack of awareness of human dignity and the absence of media education are diagnosed as the reasons for online hate speech. The social reasons for online hate speech lie in the lack of human rights education and the problems of the media. In order to improve the problems of Internet hate speech, various suggestions are proposed on the legal, social and educational levels.

Cognitive Nursing Intervention (인지적 간호중재)

  • 김명자
    • Journal of Korean Academy of Nursing
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    • v.22 no.3
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    • pp.337-351
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    • 1992
  • Nursing as it is practiced and taught, historically has been viewed as natural science. There are new movements to create a paradigm of nursing in the human sciences. A natural science methodologies elicit quantitative data from observable phenomena and reveal causal relationships. Human science methodology is the study of Unitary Man's participative experience in a situation, the simultaneity paradigm. In a theory of nursing rooted in human science assumptions about man and health are synthesized, and the practice of nursing is continuously expanded through research. To find independent nursing interventions especially cognitive nursing intervention models it has been necessary to consult a multitude of journals and text sources for references, and no one nursing textbook can be used in help patients achieve nursing goals. The goals of nursing in the simultaneity paradigm focus on the quality of life from the person's perspective. Cognitive interventions based on the person's perspective were selected from those that colleagues deemed appropriate to nursing and those that were identified in the nursing literature. They were supportive nursing care, reminiscence, meditation, relaxation and imagery. Nurses have been reluctant to make diagnoses, implement actions, and assume responsibility for this actions and this is of concern but can be understood because nurses have had little exposure to action and lack an intervention armamentarium from with which to choose actions to achieve nursing goals. Efforts in nursing education and nursing service are required to remedy this problem. Nurses must be convinced of the challenge and excitement associated with autonomous functioning. It is a characteristic of the true professional. Traditionally, nursing has prescribed one method for handling a situation. Fundamental nursing texts usually only present one way to handle a situation, because alternative interventions to achieve a client goal may be available. Considerably more research is necessary before these can be prescribed. However, unless a first step is taken, progress will not be made. The quality of health care or nursing care is enhanced when nurses transform dilemas into commited action. This is apparent from widespread experiences of nurses.

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Monitoring of Genetically Modified Bean Sprouts at Traditional Markets in Seoul and a Survey of Perception of Traditional Market Merchants and High School Students on Genetically Modified Organisms (서울 일부지역 재래시장의 유전자재조합 콩나물의 판매실태 및 상인과 일부 고등학생의 유전자재조합 식품에 대한 인식도 조사)

  • Choi, Seul-Ki;Lim, Jung-Hoon;Shin, Jee-Seong;Jeong, Jin-An;Joung, Hyo-Jee
    • Korean Journal of Community Nutrition
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    • v.15 no.5
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    • pp.679-686
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    • 2010
  • The purpose of this study is to monitor genetically modified bean sprouts at traditional markets in Seoul and to investigate perception of traditional market merchants and high school students on genetically modified organisms (GMOs). We analyzed 30 bean sprouts that were selected at 11 traditional markets in Seoul using the method of polymerase chain reaction (PCR). Also, we compared perception of GMOs between merchants (n = 30) and students (n = 126). Knowledge test about GMOs was performed by students. The result of PCR, 16.7% of bean sprouts were confirmed as GM bean sprouts (n = 5). Students had significantly more exposure to information about GMOs than merchants (p < 0.05). Major information sources about GMOs were from mass media (television, newspaper and radio). About half of subjects were not aware that they eat GMOs and GMOs are sold to consumers. Only 17.3% of subjects had constant eating intent for GMOs after perceiving foods that he/she usually eats are GMOs. 51.3% of subjects had willingness to purchase GMOs if GMOs have same quality and lower cost than natural foods. 37.2% of subjects thought that GMOs would be harmful to humans. Students had more positive perception of GMOs' side effects than merchants (p < 0.01). There was no merchant who knew labeling of GMOs. 19.1% of students knew labeling of GMOs. Students' mean percentage of correct answers of six questions about GMOs was 45.2%. Therefore, providing adequate information about GMOs is needed for consumer's choice whether to purchase GMOs or not.

In Vitro Characterization of Lactic Acid Bacteria from Indonesian Kefir Grains as Probiotics with Cholesterol-Lowering Effect

  • Yusuf, Dandy;Nuraida, Lilis;Dewanti-Hariyadi, Ratih;Hunaefi, Dase
    • Journal of Microbiology and Biotechnology
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    • v.30 no.5
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    • pp.726-732
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    • 2020
  • Indonesian kefir grains are potential sources of lactic acid bacteria (LAB) that may act as probiotics with specific functional properties. In this study we explored the potential of the probiotic and cholesterol-lowering effect of LAB isolated from Indonesian kefir grains obtained from Bogor, Bandung, Jakarta, and Yogyakarta. The results revealed that 10 isolates showed considerable survivability at low pH and bile salt with total cell reduction of ~3 log colony-forming units per milliliter after exposure to pH 2.5 and 0.5% (w/v) bile salt for 1 and 3 h, respectively. All strains exhibited strong antimicrobial activities against pathogenic bacteria and were sensitive to a wide spectrum of antibiotics but exhibited weak bile salt hydrolase activity. Identification based on 16S RNA suggested that nine isolates were Lactobacillus kefiri and one was Lactobacillus rhamnosus. The ability of the isolates to reduce cholesterol from the media varied, ranging from 22.08% to 68.75% with the highest reduction shown by L. kefiri JK17. The ability to remove cholesterol from the media decreased greatly in resting and dead cells, ranging from 14.58% to 22.08% in resting cells and from 7.89% to 18.17% in dead cells. It can be concluded that Indonesian kefir grains contain LAB potentially acting as probiotics capable of reducing cholesterol. The cholesterol-lowering effect especially occurs when the cells are metabolically active.

A study on radiation safety education, knowledge, and practice in using portable intraoral X-ray equipment of dental hygienist's (치과위생사의 이동형 구내방사선 촬영에 관한 방사선 방어 교육, 지식, 수행에 관한 연구)

  • Ryu, Jeong-Min;Kang, Bo-Sun;Kim, Seol-Hee
    • Journal of Korean society of Dental Hygiene
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    • v.17 no.6
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    • pp.1053-1065
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    • 2017
  • Objectives: The purpose of this study is to evaluate radiation safety education, knowledge and practice of dental hygienists in using handheld portable intraoral X-ray equipment and to suggest the need for radiation safety education in using handheld portable intraoral X-ray equipment. Methods: We surveyed 223 dental hygienists from July, 2017 to August in the dental clinics of Daejeon, Seoul and Gyeonggi area. Results: Radiation safety educational experience was higher in a year's career (72.9%), than 3 years experience (32.5%) (p<0.05). 82.7% of dental clinic workers took university education for radiation safety education while 55.6% of dental hospital workers took company training (p<0.05). More than 70% of the subjects did not have experience of radiation safety education about using portable intraoral X-ray. Radiation safety knowledge was highest in a year's career (p<0.05). The cumulative dose, radiation sensitivity, and lead defense knowledge were high in all subjects, but knowledge related to scattering radiation and scattering radiation sources was low. Practice of portable intraoral X-ray safety was significantly lower than knowledge. Conclusions: Knowledge of portable intraoral radiography safety is available, but performance is poor. Even with the small amount of radiation exposure, the risk is perceivable. There is a need to actively utilize the provided radiation protection products. In order to do this, efforts should be made to improve knowledge and performance of radiation safety through not only college education but also postemployment training.

Epidemiologic Investigation of an Outbreak of Shigella sonnei among Students in Bonghwa, 1999 (1999년 봉화군 일개 중.고등학교에서 발생한 세균성이질에 관한 역학조사)

  • Bae, Geun-Ryang;Lim, Hyun-Sul
    • Journal of Preventive Medicine and Public Health
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    • v.33 no.1
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    • pp.10-16
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    • 2000
  • Objectives : This study was carried out to investigate the sources of infection and modes of transmission of an outbreak of shigellosis that occurred among students of B middle and high school in Bonghwa, Korea from May 1 to 21, 1999. Methods : We conducted questionnaires to 468 students, 38 stalls and 9 food handlers twice times (May 6, May 21) for follow up and secondary attack rate. Personal details and history of illness and exposure to particular foods were sought. And we conducted rectal swab for culture to 243 students, 33 staffs and 9 food handlers. Bacteriological examinations of water in the school were done. Cases were identified as subjects who had diarrhea (two or more loose stools in a 24-hour periods) on or after May 1. Results : A total of 307 cases (attack rate: 59.6%) of 515 subject were identified, including 50 confirmed (46 students and 4 staffs) by S. sonnei. All 9 food handlers denied illness and were had rectal swab for culture at May 6 that were negative for S. sonnei. 146 of 307 reported fever, 156 had tenesmus, 44 reported vomiting, and only 5 of 307 reported blood in the stool. The median duration of diarrhea was 4 days (range: 1-18 days). The mean incubation period until onset of diarrhea was 63 hours (range: 46-144 hours) and the secondary attack rate was 2.8% (43 cases of 1,561 family members). Risk for illness was higher among students who had eaten watered kimchi at March 30 than among those who did not [301(72.7%) of 417 versus 5(9.6%) of 52; RR=7.51;95% CI=3.26-17.31]. Conclusion : The source of infection was estimated to be contaminated watered kimchi by ore or two food hardier who is presumed to be carrier.

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Modification of Medium to Examine Fecal Coliforms in Water (물에서의 분원성대장균군 검사를 위한 최적 배지 선정)

  • Lee, Eunsook;Ko, Nayun;Choi, Byungdo;Kim, Bogsoon
    • Journal of Korean Society on Water Environment
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    • v.36 no.4
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    • pp.275-283
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    • 2020
  • Fecal coliforms are indicator bacteria to evaluate fecal contamination and microbiological safety in environment water. To examine fecal coliforms by membrane filtration, 1% rosolic acid solution dissolved in sodium hydroxide(0.2 M) should be added to m-FC medium according to Korean standard method. To reduce the exposure of researchers to harmful chemicals and expenditure of unnecessary cost, we evaluated if the rosolic acid solution is required to detect fecal coliforms. For 113 samples collected from five intake sources of Seoul, 42 samples of six tributaries, and 11 samples of sewage, the number of fecal coliforms was compared in medium with or without the reagent. As a result, the number was higher in m-FC medium without the reagent, but there was not a statistically significant difference. In the water intake, m-FC medium without the reagent could be used to examine fecal coliforms except in July, August and in case of rainfall. When heterotrophic plate counts exceeded 1,000 CFU/filter, or during rainfall, there was an effect of background bacteria in two types of the medium. However, it was more appropriate to use m-FC medium with the reagent to suppress gram-positive bacteria that can grow on medium without the reagent. In the tributary and sewage samples, the effect of the background bacteria was low, allowing the use of medium without the reagent regardless rainfall. Thus, it is necessary to present in standard method that the addition of rosolic acid solution in m-FC medium can be selected according to the characteristics of samples.

A Study on the Removal Method of Radioactive Corrosion Product using its Magnetic Property (방사성 부식생성물의 자기적 성질을 이용한 제거방법에 대한 연구)

  • 송민철;공태영;이건재
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.1 no.1
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    • pp.73-79
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    • 2003
  • In a pressurized water reactor, radioactive corrosion products (CRUD) in primary coolant system are one of the major sources for the occupational radiation exposure of the personnel in a nuclear power plant. Through the recent trend of long term fuel cycle in a nuclear power Plant, radioactive corrosion products deposited in reactor core for a long time are also the cause of Axial Offset Anomaly (AOA) having m effect on reactor power by the hideout of boron. CRUD consist primarily of magnetite, nickel ferrite, cobalt ferrite, and so on. They have the characteristic of strong magnetism. Therefore it is performed the conceptual design to develop the filter which removes the CRUD by magnetic field that is generated by an arrangement of permanent and electric magnets. Contrary to the conventional filter, the proposed filter does not interrupt the fluid flow, so there is little pressure drop and it can be used continuously. It is expected to be applied as one of the technologies for removal of the CRUB.

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A Study on the Recommendation of the Candidate Substances and Methods for an Additional Designation of Special Management Materials in Occupational Safety and Health Act(OSHA) (산업안전보건법 특별관리물질의 추가 지정방법 및 후보물질 권고에 관한 연구)

  • Lee, Kwon Seob;Hong, Mun Ki;Lee, Hye Jin;Byeon, Sang-Hoon;Park, Jung Sun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.24 no.1
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    • pp.91-102
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    • 2014
  • Objectives: This study was performed in order to devise a procedure for supplementing the Special Management Materials in the Occupational Safety and Health Act and recommend candidate materials. The results are expected to be used as fundamental data for classification and criteria necessary to manage Special Management Materials in workplaces. Also, they are expected to be used as a basis for selecting target materials to nominate as additional Special Management Material. Methods: We investigated the selection standards for candidates and review ranges of data sources to nominate Special Management Materials. The substances classified as GHS(Globally Harmonized System of classification and labeling of chemicals) category 1A(known to have carcinogenic potential and reproductive toxicity for humans) or 1B(presumed to have carcinogenic potential and reproductive toxicity for humans) carcinogens and reproductive toxicants among the Controlled Hazardous Substances of the Regulation on Occupational Safety and Health Standards and substances with OELs(Occupational Exposure Limits) were inspected as the candidates for Special Management Materials. Conclusions: A seven-step procedure for selecting candidates to designate as Special Management Materials was suggested, including the setting of target chemicals for evaluation, classification of CMR(Carcinogens, Mutagens or Reproductive toxicants) by GHS classification and criteria, suggestion and selection of the candidates, and more. This study recommends 58 chemicals as qualified candidates to supplement the Special Management Materials.