• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.8
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• pp.3992-4005
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• 2018

In our current information-based society in which knowledge is a fundamental asset to production, the capability to utilize information and produce knowledge with the use of information technology (IT) has become essential to learning. Massive Open Online Courses (MOOCs) have recently been introduced in light of such changes and are recognized as an alternative to open education. MOOCs' capabilities are being acknowledged in lifelong education in terms of reeducation and knowledge sharing, and also in terms of improving teaching quality, and improving university students' levels of creativity and integrated thinking by supporting high-level content and teaching. Therefore, this study presents an extended research model that combines information system (IS) continuance and task-technology fit models. Our study researches previous literature, revealing factors of continuous use after accepting MOOCs from the learner's perspective, and analyzes the model empirically. The ideal environment for MOOCs learners is evaluated, and a strategic approach to the successful settlement and diffusion of MOOCs is presented based on this study's findings.

• Journal of the military operations research society of Korea
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• v.26 no.2
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• pp.75-89
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• 2000

This paper deals with complex system theory to describe guerrilla warfare situation using EINSTein (Enhanced ISAAC Neural Simulation Tool) simulation model. EINSTein model is an agent-based artificial "laboratory" for exploring self-organized emergent behavior in land combat. Many studies have shown that existing Lanchester equations used in most guerrilla warfare models do not describe changes of combat units, real guerrilla warfare situation and qualitative factors in combat. Future warfare will be information warfare with various weapon system and complex combat units. We have compared and tested results with Lanchester models and EINSTein model. And the EINSTein model has been applied and analyzed to guerrilla warfare model (C4I facilities, coastal, urbanized terrain critical facilities defense). The results show that the EINSTein model has a possibility to apply and analyze guerrilla warfare more properly than Lanchester models.

• Genomics & Informatics
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• v.9 no.1
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• pp.28-36
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• 2011

Most statistical methods for finding interesting genes are focusing on the summary values with large fold-changes or large variations. Very few methods consider the probe level data. We developed a new measure to detect reliability that incorporates the probe level data. This reliability measure is useful for exploring the microarray data without ignoring the probe level data. It is easy to calculate, and it can be used for all the other statistical methods as a good guideline to find real differentially expressed genes. Instead of filtering out genes before the analysis, we use whole genes in the analysis and make decisions with new reliability measures.

• Bulletin of the Korean Chemical Society
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• v.25 no.11
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• pp.1676-1680
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• 2004

We demonstrate that wide-angle X-ray scattering pattern from photoactive yellow protein (PYP) in solution using a high flux third generation synchrotron X-ray source reflects not only the overall structure, but also fine structures of the protein. X-ray scattering data from PYP in solution have been collected in q ranges from 0.02 ${\AA}^{-1}$ to 2.8 ${\AA}^{-1}$. These data are sensitive to the protein structure and consistent with the calculation based on known crystallographic atomic coordinates. Theoretical scattering patterns were also calculated for the intermediates during the photocycle of PYP to estimate the feasibility of time-resolved wide-angle X-ray scattering experiments on such proteins. These results demonstrate the possibility of using the wide-angle solution X-ray scattering as a quantitative monitor of photo-induced structural changes in PYP.

• International journal of advanced smart convergence
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• v.10 no.4
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• pp.141-148
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• 2021

This study was tried to explore the mediating effect of workplace learning and self-efficacy on the relationship between technostress and job satisfaction in convalescent hospital nurses. Data were collected from 149 nurses working at one of 10 convalescent hospitals located in Korea's D region and between July 20 and August 12, 2019 and analyzed using SPSS 24.0. The mediating effects of workplace learning and self-efficacy in the relationship between technostress and job satisfaction were investigated by conducting hierarchical regression analysis and testing for significance based on bootstrapping p values. We found that workplace learning had a complete mediating effect, and self-efficacy a partial mediating effect, in the relationship between technostress and job satisfaction in convalescent hospital nurses. Exploring diverse factors and environmental features affecting job satisfaction in convalescent hospital nurses is highly relevant to clinicians, especially given the gradually increasing number of convalescent hospitals, changes during the era of technology fusion, and the strategic demands arising from an aging society.

• Journal of Korea Multimedia Society
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• v.25 no.10
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• pp.1457-1467
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• 2022

The relationship between film and culture is established through a shared focus on people's lives. Culture changes at different times, which makes a dynamic and complex relationship between film and culture. Understanding this relationship helps to provide better support for current filmmaking. The purpose of this study is to provide insights into the macro issue of film and culture by exploring the relationship between film theme and culture concept. To this end, we used a case study to explore the connection between themes and culture concepts in Disney's Mulan (1998, 2020) through literature and analyses of culture concepts (Chinese "imagery" and Postmodernism). The study concludes that, "Culture assemblage" and "Vision is king" have become cultural trends that influence the creation of film theme and style to a certain extent; how to balance the relationship between the core idea of film theme and the external forms is an important issue in current filmmaking. The article contributes to promote thinking about culture in film creation, and its research perspective on different cultures and histories is innovative.

• Asia Marketing Journal
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• v.18 no.1
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• pp.1-22
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• 2016

Studies in key account management (KAM) have identified the importance of cross-functional coordination in firms to effectively implement KAM. However, these studies have ignored how companies integrate KAM and other customer management (non-KAM). This paper explores coordination design between KAM units and non-KAM units by analyzing a case study through three dimensions: front-end coordination, back-end-coordination, and organizational translation at the beginning of research. The case study shows that non-KAM conditions can require a modification of the coordination design. This research performs an in-depth analysis of changes in the implementation of sales reforms for an IT-related machinery and system vendor in Japan. Data sources include interviews with KAM units and non-KAM sales units and an analysis of secondary data. This paper suggests that studying the coordination between KAM units and non-KAM units will further our understanding of internal coordination in KAM research.

• International Journal of Internet, Broadcasting and Communication
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• v.16 no.1
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• pp.253-260
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• 2024

We studied to aim for exploring practical approaches to enhance the effectiveness of creativity education by using artificial intelligence and the metaverse in the field of media contents. Recognizing the need for educational innovation to adapt to the accelerating changes driven by the advancements in artificial intelligence and the metaverse, and considering the increasing importance of fostering creativity as a key competitive advantage for future talents, we focused on research implementing creativity education in the media contents domain. To achieve this, we conducted this study during a semester-long media contents course utilizing artificial intelligence and the metaverse in real classroom setting. We involved in this study collecting feedback and opinions from students to investigate and identify effective strategies for enhancing the impact of creativity education. As a result, we proposed the utility of media contents class using artificial intelligence and the metaverse in enhancing students' creativity. By elucidating which teaching methods are most effective, we contributed to derive beneficial outcomes for media contents creative education.

• SUVANNABHUMI
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• v.16 no.1
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• pp.147-173
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• 2024

Nguyễn Huy Thiệp is a pillar in Vietnamese cultural life after the Second Indochina War, and the fates of men and women at the beginning of Đổi mới (Renovation) is one of the prominent themes in his short stories. To show off sexual power, seek glory, and maintain his dominant position, Thiệp's heroes engage in a game of oppressing the weak, hunting animals, and harassing women. However, due to the complex changes in social life, moral values, and gender inequality, men in the postwar period quickly experienced the feeling of humiliation, impotence, and failure. In turn, the sophisticated aspects of masculinity demonstrate the cultural and ethical concerns of contemporary Vietnamese society. By exploring the multidimensional nature of masculinity expressed in Thiệp's stories, this study aims to resolve misconceptions about gender and the relationship between men and women in his work.

• Biomolecules & Therapeutics
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• v.32 no.1
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• pp.13-24
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• 2024

Cytokines influence the overall cancer immune cycle by triggering tumor antigen expression, antigen presenting, immune cell priming and activation, effector immune cell recruitment and infiltration to cancer, and cancer killing in the tumor microenvironment (TME). Therefore, cytokines have been considered potential anti-cancer immunotherapy, and cytokine-based anti-cancer therapies continue to be an active area of research and development in the field of cancer immunotherapy, with ongoing clinical trials exploring new strategies to improve efficacy and safety. In this review, we examine past and present clinical developments for major anticancer cytokines, including interleukins (IL-2, IL-15, IL-12, IL-21), interferons, TGF-beta, and GM-CSF. We identify the current status and changes in the technology platform being applied to cytokine-based immune anti-cancer therapeutics. Through this, we discuss the opportunities and challenges of cytokine-based immune anti-cancer treatments in the current immunotherapy market and suggest development directions to enhance the clinical use of cytokines as immuno-anticancer drugs in the future.