• Title/Summary/Keyword: experimental warming

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Blood Gas Management of a Membrane Oxygenator During Cardiac Surgery with Deep Hypothermic Circulatory Arrest (막형산화기에 의한 저체온 순환정지 심장수술시 혈액가스 조절)

  • Kim, W. G.;Lim, C.;Baek, Y. H.
    • Journal of Biomedical Engineering Research
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    • v.19 no.3
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    • pp.279-284
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    • 1998
  • Deep hypothermic circulatory arrest(DHCA), in which systemic temperatures of 2$0^{\circ}C$ or less are used to allow temporary cessation of the circulation, is an useful adjunct in cardiac surgery. Because man in natural circumstances is never exposed to the extreme hypothermic condition, however, one of the controversial aspects is appropriate blood gas management($\alpha$STAT versus PH-STAT) during DHCA. This study aims to compare $\alpha$STAT with PH-STAT management for control of blood gases in experimental cardiopulmonary bypass(CPB) circuits with a membrane oxygenator. Fourteen young pigs were assigned to one of two strategies of gas manipulation. After a median sternotomy, CPB was established. Core cooling was initiated and continued until nasopharyngeal temperature fell below 2$0^{\circ}C$. The flow rate was set at 2,500 ml/min. Once their temperatures were below 2$0^{\circ}C$, the animals were subjected to circulatory arrest for 40mins. During cooling, blood gas was maintained according to either $\alpha$$\alpha$STAT or pH-STAT strategies. After DHCA, the body was rewarmed to normal body temperature. Arterial blood gases were measured before the onset of CPB, before cooling, before DHCA, at the point of 27$^{\circ}C$ during re-warming, on completion of re-warming. Cooling time was significantly shorter in $\alpha$-STAT than PH-STAT strategy, while there was no significant differences in rewarming time between two groups. Carbon dioxide was added between 5.5 and 3.0% in PH-STAT, while no carbon dioxide was added in $\alpha$STAT management. Amounts of oxygen administration were gradually lowered as temperature decreased. In this way, criteria of PH, PaCO, and PaO adjustments were satisfied in both $\alpha$STAT and PH-STAT management groups.

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An Experimental Study for the Effective Use Scheme of Snow Removal Materials on Road (도로 제설재의 효과적 사용방안에 관한 실험적 연구)

  • Do, Jongnam;Kim, Taesoo;Lee, Chanbok;Kim, Yeonjoong;Chun, Byungsik
    • Journal of the Korean GEO-environmental Society
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    • v.13 no.2
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    • pp.5-17
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    • 2012
  • The amount of snow due to global warming and climate change has recently increased. The effective management of snow removal materials will be required. First, on the basis of domestic winter temperature, it is not necessary to get a baseline to less than the freezing point of $-52^{\circ}C$ for the calcium chloride($CaCl_2$) of 30%.. In terms of cost comparison between calcium chloride($CaCl_2$) and sodium chloride($NaCl$), the calcium chloride($CaCl_2$) is 2 to 3 times more expensive, and the supply of the calcium chloride($CaCl_2$) is not produced in domestic country and is in the conditions that have to imports all needed. Accordingly, the effective use scheme of snow removal materials should be considered to multifaceted ways. Thus, the objective of this study is to develop effective method and to replace from calcium choride($CaCl_2$) to sodium chloride($NaCl$) solution in the current snow removal operating system that uses a pre-wetted salt spreading method. The effective method that equals to the quality of the existing snow removal materials was developed in this study through performance tests for deicing chemicals, corrosion test of steel and freezing and thawing tests of concrete.

Amphibian Biotope Planning to Research on Reproduction of Bombina orientalis (무당개구리(Bombina orientalis) 번식 연구를 위한 양서류 바이오톱(amphibian biotope) 조성)

  • Yoon, Seong-Il;Park, Chan-Jin;Bhan, Young-Ho;Gye, Myung-Chan
    • Korean Journal of Environmental Biology
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    • v.26 no.1
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    • pp.22-29
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    • 2008
  • Bombina orientalis, or Korean fire-bellied toad is belonging to Class Amphinia, Order Anura, Family Bombinatoridae, Genus Bombina. Ecological characteristics, such as small size, slow moving and swimming, gentle attitude to other species, under laboratory and/or wild condition lead the toad as suitable experimental animals with easy handling. Seasonal reproductive biology except breeding season (usually from Apr. to late Jun.) are unknown still caused by sampling methods for hibernating specimens have not been established yet. Most species of amphibian, include B. orientalis, are declined around the world related with global warming, therefore, wild caught specimen for any purposes must be limited controled soon. Even though, some pre-studies of biotope for increasing biodiversity have been reported, construction of an artificial biotope to get natural breeding cycling specimen for study of amphibian reproduction is unique modelling and only trial. In an effort to set year-round sampling for study of reproduction of B. orientalis, we suggest protocols for planning, construction manual and SOP(Standard Operation Process) to manage amphibian biotope. During pilot operation of a designed and constructed biotope, the seasonal acclimation during winter hibernation of B. orientalis were successful. It will be helpful for studying the reproductive biology of wild amphibians in temperate region and allow to get reasonable research conditions in amphibian laboratory.

Development and Applications of Mathematical Proof Learning-Teaching Methods: the Generative-Convergent Model (증명학습에서 생성-수렴 수업 모형의 개발과 적용)

  • 이종희;김부미
    • School Mathematics
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    • v.6 no.1
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    • pp.59-90
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    • 2004
  • This study has been established with two purposes. The first one is to development the learning-teaching model for enhancing students' creative proof capacities in the domain of demonstrative geometry as subject content. The second one is to aim at experimentally testing its effectiveness. First, we develop the learning-teaching model for enhancing students' proof capacities. This model is named the generative-convergent model based instruction. It consists of the following components: warming-up activities, generative activities, convergent activities, reflective discussion, other high quality resources etc. Second, to investigate the effects of the generative-convergent model based instruction, 160 8th-grade students are selected and are assigned to experimental and control groups. We focused that the generative-convergent model based instruction would be more effective than the traditional teaching method for improving middle school students' proof-writing capacities and error remediation. In conclusion, the generative-convergent model based instruction would be useful for improving middle grade students' proof-writing capacities. We suggest the following: first, it is required to refine the generative-convergent model for enhancing proof-problem solving capacities; second, it is also required to develop teaching materials in the generative-convergent model based instruction.

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Changes of Thyroid Hormone Levels in Plasma of Rats during Cold Exposure (저온환경 적응에 있어서의 갑상선 Hormone의 변동)

  • Lee, H.W.;Kim, W.J.;Hong, S.S.;Kim, H.S.;Hong, S.U.
    • The Korean Journal of Pharmacology
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    • v.17 no.2
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    • pp.37-45
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    • 1981
  • The importance of thyroid hormones for the survival of rats in the cold is along-established fact. Hypothyroid animals are unable to survive in a cold environment. It was also reported that acute exposure of rats, guinea pigs and rabbits to cold produced an increased secretion of TSH and thereby thyroid hormone secretion within 10 to 30 min, but this increase of thyroid activity disappeared quite rapidly during warming. However, in human study no significant difference was found in the concentration of $T_4$, TSH and cortisol between summer and winter. But plasma $T_3$ concentration was increased significantly in winter in 56 adult men. On the other hand, it has been also known that catecholamines are important in the maintenance of body temperature of rat exposured to cold. Abundant evidences suggest that the sympathetic nervous system is involved in the activation of nonshivering thermogenesis and that thyroid hormone metabolism and secretion are influenced by catecholamines and consequently by the activity of the sympatheticadrenal system. Many of the metabolic effects of catecholamines are associated with an increase in the level of cAMP mediated through activation of adenylate cyclase which converts ATP to cAMP. Other studies have shown that thyroid hormones affect the amount of adenylate cyclase present in the adipose tissue. On the other hand. it was also reported that a particulate cAMP phosphodiesterase activity in fat cells was modulated by the action of thyroid hormones. The objective of the present study was to determine the interaction between thyroid activity and cyclic nucleotides during acute exposure to cold. Albino rats weighing around 200 g were used as the experimental animal. The room temperature group was kept at $25^{\circ}C$ and the cold-exposured group was kept at $4^{\circ}C$ for 1 week or 2 weeks. Each group was subdivided into three subgroups; control, KI, and MTU group. At the end of experiment the animals were etherized and blood was taken from abdominal aorta for $T_4,\;T_3$ and cyclic nucleotides. The determinations of $T_3,\;T_4$ and cyclic nucleotides were carried out with a radioimmunoassay(RIA) method. The results were summerized as followings. 1) A significant increase of thyroid weight was observed in rats exposured to cold for 2 weeks. Furthermore, in rats administered MTU while to exposure to cold the thyroid weight was also increased significantly. 2) After 2 weeks $T_3$ concentration in the plasma of cold-exposured rats was significantly increased in KI group and MTU group as well as in control group. On the contrary, after 2 weeks of cold exposure $T_4$ level was decreased in control group. 3) In the case of cyclic nucleotides, plasma cAMP was increased in the control group after 1 or 2 weeks of cold exposure. However, cAMP level in plasma was rather significantly decreased in KI group and MTU group as well as in control group.

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An Analysis of Local Quantity of Carbon Absorption, Fixation and Emission by Using GIS

  • Kim, Hyeon-Tae;Moon, Byeong-Eun;Choi, Eun-Gyu;Kim, Chi-Ho;Ryou, Young-Sun;Kim, Jong-Goo
    • Journal of the Korea Organic Resources Recycling Association
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    • v.22 no.1
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    • pp.40-48
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    • 2014
  • Due to increasing greenhouse gas emissions, global warming and abnormal weather phenomena it has become important on a national level to keep a count of greenhouse gases being emitted. We want to take advantage of any selected area, as the basic data for the calculation of greenhouse gas emissions, Forest and Grassland, Paddy fields, and Fields(crops), Greenhouse(crops), Pig farm, Cattle farm, Farm household(populations, agricultural machinery) and Vehicle, the basic building blocks shots with a small amount of per-unit basis, the statistics calculated based on regional carbon emissions through the literature and experimental. Carbon absorption 772,960 ton C/year, amount of fixation 487,477 ton C/year, amount of emission 1,112,607 ton C/year were noted in Gimje-si, and amount of carbon absorption 55,559 ton C/year, amount of fixation 25,864 ton C/year, amount of emissions 58,355 ton C/year in Gongdeok-myeon, respectively. The carbon absorption at Hwangsan-ri is 25,107 ton C/year, fixation 4,301 ton C/year, and emission 20,330 ton C/year respectively. We were able to estimate the amount of carbon according to the specific characteristics of each unit village, then expanding it to a large-scale and comparative analysis, therefore we were able to obtain basic data on the national levels of carbon absorption.

A Study on Combustion and Emission Characteristics of a Diesel Engine Fuelled with Pyrolysis Oil-Ethanol and Pilot Diesel (바이오원유-에탄올/파일럿 디젤유 이종연료 혼소를 통한 디젤엔진의 연소 및 배출가스 특성에 관한 연구)

  • Kim, Min-Jae;Lee, Seok-Hwan;Cho, Jeong-Kwon;Yoon, Jun-Kyu;Lim, Jong-Han
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.5
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    • pp.420-427
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    • 2017
  • Recently, the depletion of fossil fuels, global warming and environmental pollution have emerged as a worldwide problem, and studies of new renewable energy sources have been progressed. Among the many renewable energy sources, the use of bio fuel has the potential to displace fossil fuels due to low price, easy to handle, and the abundant sources. Pyrolysis oil (PO) derived from waste wood and sawdust is considered an alternative fuel for use in diesel engines. On the other hand, PO is limited to diesel engines because of its low cetane number, high viscosity, high acidity, and low energy density. Therefore, to improve its poor properties, PO was mixed with alcohol fuels, such as ethanol. Early mixing with ethanol has the benefit of improving the storage and handling properties of the PO. Furthermore, a PO-ethanol blended fuel was injected separately, which can be fired through pilot-injected diesel in a dual-injection diesel engine. The experimental results showed that the substitution of diesel with blended fuel increases the amount of HC and CO, but reduces the NOx and PM significantly.

A Fundamental Study for Design of Electric Energy Harvesting Device using PZT on the Road (도로용 압전발전체 시험모듈 설계를 위한 기초 실험 연구)

  • Lee, Jae-Jun;Ryu, Seung-Ki;Moon, Hak-Yong;Kwon, Soo-Ahn
    • International Journal of Highway Engineering
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    • v.13 no.4
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    • pp.159-166
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    • 2011
  • Green house gas emissions are increasing as development of the industrial economy of the international community. Many countries in the world are endeavoring to reduce green house gas emissions under severe climate change. In order to protect grobal warming, government is trying to reduce green gas emissions under "Low Carbon Green Growth Policy" and investing climiate-firendly industries such as renewable energy harvesting. Renewable energy has been rapidly developing as a result of investment for development technology of using natural energy such as solar, wind, tidal, etc. There are lots of waste energy in the road space. However, nobody is not interested in waste energy from the road space. This paper present a fundamentally experimental study of energy harvesting technique to use waste energy in the road. The waste energy in the road is covered a pressure and impact of vehicles on the road, the radiant heat from asphalt pavement, road noise and vibration etc. In this study, an energy harvesting device using piezoelectric element is proposed and various tests are conducted to investigate a characteristic of this device as function of impact loading based on piezoelectric effect behavior. This paper shows the energy harvesting results of the device using domestic piezoelectirc element as a function of impact load size and pavement types.

Experimental Study on Structure Characteristics of Particulate Matter emitted from Ship at Various Sampling Conditions (다양한 샘플링 조건에 따른 선박 배기가스 내 입자상물질의 구조 특성에 관한 실험 연구)

  • Lee, Won-Ju;Jang, Se-Hyun;Kim, Sung-Yoon;Kang, Mu-Kyoung;Chun, Kang-Woo;Cho, Kwon-Hae;Yoon, Seok-Hun;Choi, Jae-Hyuk
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.22 no.5
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    • pp.547-553
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    • 2016
  • Black carbon (BC) contained in particulate matter (PM) originating from the exhaust gases of ships' diesel engines has been receiving great attention as a cause of glacial melting and warming in the polar regions. In this study, we took samples from various locations of PM emitted from the training ship (T/S) HANBADA's main engine, in cooperation with the Korea Maritime and Ocean University. We analyzed the structure and characteristics of these samples using high-resolution transmission electron microscopy (HR-TEM) and applied our findings as fundamental research for developing PM reduction technology. We also employed our results to determine appropriate preemptive action to meet upcoming PM/BC regulations. In addition, we confirmed the emission trend of pollutants from exhaust gases under various engine operating conditions using an exhaust gas analyzer. Results obtained from the analysis of HR-TEM images showed that the structure of the PM is chain-like wispy agglomerates consisting of a number of individual spherical particles. As the sampling location was moved away from the turbo charger (T/C) towards the funnel, more condensates were observed at a low temperature and the molecular structure of the PM lost its characteristic BC structure as an amorphous structure gradually appeared. Furthermore, through the analysis of exhaust gases, we predicted a decrease in PM concentration in the exhaust stream as engine rpm increase.

Designation of fuel oil scrubber nozzle positioning using CFD analysis and PIV methods (CFD 해석 및 PIV 실험을 통한 연료유 스크러버의 노즐 위치선정)

  • Kim, In-Cheol;Kim, Chang-Goo;Park, Sung-Jin;Cho, Dong-Yeon;Lee, Young-Ho
    • Journal of Advanced Marine Engineering and Technology
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    • v.39 no.7
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    • pp.773-778
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    • 2015
  • Global warming has recently become an issue that has resulted in a growing trend to minimize environmental pollution. The International Maritime Organization (IMO) has shown that the majority of marine atmospheric pollution occurs as a result of emissions from marine vessels. Therefore, the environmental regulations and emission standards regarding marine vessels have gradually become stricter, and the research and development in this area is experiencing significant progress. In this study, a nozzle for a fuel oil scrubber was investigated using computational fluid dynamics (CFD) and particle imaging velocimetry (PIV). Experiments were conducted on scaled-down model of the scrubber to determine its performance, which was then compared with CFD results. Based on the experimental results, it was found that at a spray angle of $66^{\circ}$, the spray velocity at the nozzle was 20.1 m/s. From this comparison, a full-scale scrubber model was analyzed using CFD, and the effect of the positioning of the nozzle was studied.