• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7629-7634
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• 2013

Background: Cylin D1(CCDN1) is an important regulator of the cell cycle whose alterations are thought to be involved in cancer development. There have been many studies indicating CCDN1 amplification or over-expression in a variety of cancer types. In addition to gene amplification, the G870A polymorphism may be related with altered CCDN1 activity, and therefore with cancer development. This hypothesis has been tested in different cancer types but results have been contradictory. We therefore aimed to investigate any relationship between CCDN1 A870G genotypes and laryngeal squamous cell cancer development and progression. Materials and Methods: A total of 68 Turkish patients with primary laryngeal squamous cell cancer and 133 healthy controls were enrolled. Polymerase chain reaction-restriction fragment length polymorphism analysis was used to determine the CCDN1 genotypes. Results: No significant association was detected between CCDN1 genotypes and laryngeal squamous cell cancer (LxSCCa) development. Similarly CCDN1 genotypes were not related to clinical parameters of Lx SCCa. However, there was a very significant association between CCDN1 G allele and presence of perineural invasion (p=0.003; OR: 1.464; CI% 1.073-1.999). CCDN1 G allele frequency was significantly higher in the individuals with perineural invasion (85.7%) when compared to those without (58.5%). The 2 patients who died of disease were both found to possess the GG genotype. Conclusions: These results pose a controversy in suggesting a protective role of the G allele against LxSCCa development and support the association of CCDN1 gene GG genotype with mortality in patients with LxSCCa.

• Asian Oncology Nursing
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• v.3 no.2
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• pp.112-121
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• 2003

The purpose of these study was to analyze the contents and trend of researches done on oncology nursing in the past five years in Korea and to suggest its direction for the future research. Methods: 214 nursing studies published from 1998 to 2003 were selected for the analysis. They were examined for the source, design of study, type of subjects, the intervention outcomes of experimental research, the key words and theme of the oncology research. Results: 1. 139(64.9%) of 214 studies were masters thesis and doctoral dissertations. There were 196(91.6%) quantitative researches and 18 qualitative researches. Quantitative research consisted of 28(14.3%) experimental and 168(85.7%) non- experimental studies. Among non-experimental studies, there were 53 correlations, 78 descriptives, 14 comparatives and 23 methodological studies. 2.The main subjects of the study were cancer patients in general(43.7%) and breast cancer patients (18.3%). According to the treatment types, patients receiving chemotherapy were the highest number distribution as 23 of all researches. 3. Social support, fatigue, stress, hope, and quality of life were the most frequently used concepts in correlational studies.4. Education, providing information, oral care, exercise, relaxation and foot massage were the most frequent nursing interventions. Most frequently measured outcomes variable were self-care, pain control, nausea & vomiting, oral discomfort and anxiety. 5. Key words used most frequently were quality of life, educational need, pain controls and fatigue. 6. The themes of qualitative researches were illness experience, family experience and adaptation process. More than 50% of qualitative researches used phenomenologic method. Conclusion: Researches on cancer nursing in Korea have been increased. Descriptive design is being dominant and few experimental studies are being done For the future, it is necessary to conduct international studies to compare, replicate and to establish the effective nursing interventions.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.50 no.4
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• pp.366-371
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• 2017

Six experimental diets for juvenile sea cucumbers Apostichopus japonicus were evaluated and compared with current commercial diets. Sea cucumbers (50 per tank; initial mean weight $2.3{\pm}0.1g$) in three replicates of seven groups were fed one of six experimental diets (ED1, 20% wild-harvested Sargassum thunbergii powder; ED2, 20% commercial S. thunbergii powder; ED3, 20% Undaria pinnatifida and Ascophyllum nodosum powders; ED4, 40% U. pinnatifida and A. nodosum powders; ED5, 10% brewer's yeast; and ED6, 10% sea shell powder) or a commercial diet (CD) for 28 weeks. The survival rate in all groups was 85-94%, with no significant difference among the experimental groups. The mean body weight of the sea cucumbers was significantly different among the experimental groups 6 weeks after the feeding trial. The final mean weight of the sea cucumbers was highest in ED1, ED3, and ED4, followed by ED6, ED5, ED2, and CD, in decreasing order. The results of this study suggest that U. pinnatifida and A. nodosum powders could provide a substitute for the S. thunbergii powder commonly used in commercial sea cucumber diets. Thus, the EP4 diet formulation, which contains no S. thunbergii, could be used as a practical feed for juvenile sea cucumbers.

• Journal of Ocean Engineering and Technology
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• v.31 no.2
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• pp.81-90
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• 2017

The 1MW OTEC (Ocean Thermal Energy Conversion) platform was designed for application in equatorial seas. In this study, the OTEC platform was investigated using numerical and experimental methods. An octagon-shaped OTEC platform was investigated using the Ocean Engineering Basin of KRISO. These experiments included various tests of regular waves, irregular waves and irregular waves with current (wave+current). The responses of the platform in regular waves showed good agreement between the numerical and experimental results, including the motion RAO, wave run up, and mean drift force. The peak period of heave and pitch motions were observed around 0.5 rad/s, and the effect of the total reflection was found under short wave conditions. The standard deviation (STD) of the platform motion was checked in irregular waves of equatorial and Hawaiian seas. The STD of the pitch was less than $4^{\circ}$ different from the operability requirement under equatorial conditions and the surge STD of the wave frequency showed good agreement between the numerical and experimental results. The STD values of the surge and pitch were increased 66.6% and 92.8% by the current effects in irregular waves, but the pitch STD was less than $4^{\circ}$ under equatorial conditions. This study showed that the STD of the surge was affected by spring effects. Thus, the watch circle of the platform and tension of the mooring lines must be evaluated for a specific design in the future.

• Journal of Environmental Science International
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• v.33 no.1
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• pp.43-57
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• 2024

The possible experimental time for cloud seeding was analyzed in South Korea. Rain gauge and radar precipitation data collected from September 2017 to August 2022 in from the three main target stations of cloud seeding experimentation (Daegwallyeong, Seoul, and Boryeong) were analyzed. In this study, the assumption that rainfall and cloud enhancement originating from the atmospheric updraft is a necessary condition for the cloud seeding experiment was applied. First, monthly and seasonal means of the precipitation duration and frequency were analyzed and cloud seeding experiments performed in the past were also reanalyzed. Results of analysis indicated that the experiments were possible during a monthly average of 7,025 minutes (117 times) in Daegwallyeong, 4,849 minutes (81 times) in Seoul, and 5,558 minutes (93 times) in Boryeong, if experimental limitations such as the insufficient availability of aircraft is not considered. The seasonal average results showed that the possible experimental time is the highest in summer at all three stations, which seems to be owing to the highest precipitable water in this period. Using the radar-converted precipitation data, the cloud seeding experiments were shown to be possible for 970-1,406 hours (11-16%) per year in these three regions in South Korea. This long possible experimental time suggests that longer duration, more than the previous period of 1 hour, cloud seeding experiments are available, and can contribute to achieving a large accumulated amount of enhanced rainfall.

• The Korean Journal of Food And Nutrition
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• v.31 no.1
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• pp.80-88
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• 2018

This study was conducted to develop easily chewable Korean rice cake (Garaedduk) for the elderly while maintaining its original form and flavor. We developed two types of easy-to-chew Garaedduk products by adding starch-degrading enzyme or trehalose, respectively. Characteristics of Garaedduk products were investigated and comparative analysis was carried out between control and experimental groups. The water content of control and enzyme-added Garaedduk was 43.55% and 44.11%, respectively, which was significantly higher than trehalose-added Garaedduk (40.30%) as free water content was reduced by the formation of hydrogen bonds between trehalose and water molecules. Due to the browning of reducing sugar produced by the decomposition of rice starch, Hunter b-value of enzyme-added Garaedduk was significantly higher compared to others. Hardness, adhesiveness, gumminess, and chewiness of experimental groups were lower than the control group. Consumer test scores showed significant differences with respect to overall liking, chewiness, and swallowing between control and experimental groups. Elderly preferred experimental Garaedduks over control and the experimental groups were evaluated to be softer, easily chewable, and swallowable.

• Journal of Ocean Engineering and Technology
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• v.36 no.4
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• pp.243-250
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• 2022

Subsea power cables are subjected to various external loads induced by environmental and mechanical factors during manufacturing, shipping, and installation. Therefore, the prediction of the structural strength is essential. In this study, experimental and theoretical analyses were performed to investigate the axial stiffness of subsea power cables. A uniaxial tensile test of a 6.5 m three-core AC inter-array subsea power cable was carried out using a 10 MN hydraulic actuator. In addition, the resultant force was measured as a function of displacement. The theoretical model proposed by Witz and Tan (1992) was used to numerically predict the axial stiffness of the specimen. The Newton-Raphson method was employed to solve the governing equation in the theoretical analysis. A comparison of the experimental and theoretical results for axial stiffness revealed satisfactory agreement. In addition, the predicted axial stiffness was linear notwithstanding the nonlinear geometry of the subsea power cable or the nonlinearity of the governing equation. The feasibility of both experimental and theoretical framework for predicting the axial stiffness of subsea power cables was validated. Nevertheless, the need for further numerical study using the finite element method to validate the framework is acknowledged.

• Journal of East-West Nursing Research
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• v.15 no.1
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• pp.54-62
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• 2009

Purpose: The purpose of this study was to examine the effects of relaxation therapy to reduce anxiety level among spinal anesthesia surgery patients. Methods: The study employed a quasi-experimental pre-and-posttest design with nonequivalent control group. The experimental group was provided with the 15-min muscle relaxation therapy on the day before the surgery and an hour before the spinal anesthesia. Data were collected from 44 patients (22 in experimental and 22 in control group) who were planned to have spinal anesthesia surgery from an orthopedic surgery department at a general hospital in Seoul from January 13 to March 21, 2006. Results: The experimental group reported lower level of state anxiety after the surgery (23.18 vs. 33.64) than did control group but was not statistically significant. There were no significant differences in blood pressure or pulse rate between experimental and control groups after surgery. Conclusions: The further research should be conducted to polish the muscle relaxation therapy for various types of patients and to create more comfortable environment setting for application of the therapy. The muscle relaxation therapy may be a convenient and useful nursing intervention to reduce anxiety among spinal anesthesia surgery patients if more studies prove its effectiveness.

• Advances in nano research
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• v.14 no.5
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• pp.443-450
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• 2023

Carbon nanotubes (CNTs) have received increased interest in reinforcing research for polymer matrix composites due to their exceptional mechanical characteristics. Its high surface area/volume ratio and aspect ratio enable polymer-based composites to make the most of its features. This study focuses on the experimental tensile testing and fabrication of carbon nanotube reinforced composite (CNTRC) beams, exploring various micromechanical models. By examining the performance of these models alongside experimental results, the research aims to better understand and optimize the mechanical properties of CNTRC materials. Tensile properties of neat epoxy and 0.3%; 0.4% and 0.5% by CNT reinforced laminated single layer (0°/90°) carbon fiber composite beams were investigated. The composite plates were produced in accordance with ASTM D7264 standard. The tensile test was performed in order to see the mechanical properties of the composite beams. The results showed that the optimum amount of CNT was 0.3% based on the tensile capacity. The capacity was significantly reduced when 0.4% CNT was utilized. Moreover, the experimental results are compared with Finite Element Models using ABAQUS. Hashin Failure Criteria was utilized to predict the tensile capacity. Good conformance was observed between experimental and numerical models. More importantly is that Young' Moduli of the specimens is compared with the prediction Halpin-Tsai and Mixture-Rule. Although Halpin-Tsai can accurately predict the Young's Moduli of the specimens, the accuracy of Mixture-Rule was significantly low.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09b
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• pp.997-997
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• 2006