• 제목/요약/키워드: exclusion criteria

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산후 오로부절 및 자궁 복구 불완전에 대한 생화탕(生化湯) 치료의 효과 : 체계적 문헌고찰과 메타분석 (Saenghwa-tang Treatment on Postpartum Prolonged Lochia and Uterine Subinvolution: a Systematic Review and Meta-Analysis)

  • 송지윤;김동철
    • 대한한방부인과학회지
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    • 제36권4호
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    • pp.121-139
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    • 2023
  • Objectives: This study was performed to analyze randomized controlled trial, which studied the effect of Saenghwa-tang treatment on postpartum prolonged lochia and uterine subinvolution. Methods: Researchers searched for randomized controlled trial of based on postpartum prolonged lochia, uterine subinvolution and Saenghwa-tang. The paper search was conducted through 6 online databases on August 10, 2023. Results: 8 studies were included after selection and exclusion criteria. 5 studies compared Saenghwa-tang alone with western medicine. 3 studies compared combined treatment of Saenghwa-tang and western medicine, with western medicine alone. Comparing with control group, the treatment group showed statistically significant improvement on total effective rate, uterine involution, serum fibrinogen, D-dimer, viscosity of blood and plasma, Erythrocyte aggregation, and various symptoms. Conclusions: This study suggests that Saenghwa-tang has benefit for treating prolonged lochia and uterine subinvolution. For reliable evidence, further research is needed to establish safety of Saenghwa-tang, standardize diagnosis criteria and specify the treatment course.

Electroacupuncture Treatment for Post-Stroke Foot Drop: A Systemic Review of Randomized Controlled Trials

  • Hye Jeong Jo;Go Eun Chae;Hyun Woo Kim;Young Jin Lee;Ahra Koh;Ji Eun Choi;So Jung Kim;Woo Young Kim
    • Journal of Acupuncture Research
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    • 제41권2호
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    • pp.75-86
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    • 2024
  • A review of randomized controlled trials (RCTs) using electroacupuncture (EA) to treat patients with foot drop was performed to analyze the effectiveness of EA for this condition. Relevant studies (n = 183) from 7 databases (Cochrane Library, Excerpta Medica Database, PubMed, China National Knowledge Infrastructure, Korean Studies Information Service System, Research Information Sharing Service, and Oriental Medicine Advanced Searching Integrated System) were selected based on the inclusion and exclusion criteria, and 12 RCTs met the selection criteria. In all 12 studies, EA showed significantly positive changes. In most indicators, positive changes were observed in the EA group compared with that in the control group. Significant increases were confirmed in muscle strength-related indicators such as the Fugl-Meyer motor scale, surface electromyography, active range of motion, and gait-related indicators such as the Tinetti score, maximum walking speed, and Berg balance scale. No notable adverse events were reported. EA is suggested as an effective treatment for post-stroke foot drop; however, more RCTs are required.

의적클레임검토 유형론 (Typology of the medical claims review)

  • 이신형
    • 보험의학회지
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    • 제26권
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    • pp.41-53
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    • 2007
  • In the course of insurance claim administration, medical experts' opinions are called medical claim reviews. They are classified into two main categories: medical verification and counsel for claim staff. Medical verification compare between product coverage and the insured's physical condition. Medical counsel for claim staff is advice for claim staff when they have a question about medical knowledge to make a claim decision. A common example of medical verification is insurance coding of pituitary apoplexy. Some clinicians have insisted that the ICD coding of pituitary apoplexy is l63 of cerebral infarction, but the exclusion criteria of I code show that neoplasm is coded as C00 to D48. Thus, pituitary apoplexy must be coded as D33. An example of medical counsel for claim staff is interpretation of some medical conditions. It is divided into UCR(usual, customary, and reasonable) assessment, assessment of causality, and so on. Disability evaluation is another subject of medical counsel for claim staff. The final claim decision must be made by claim staff because only the claim staff have the authority of claim decision. Medical claims review is only an expert's opinion.

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정보제공이 외래 의식 하 수술, 시술 환자의 불안에 미치는 영향: 체계적 문헌고찰 (Effects of the Provision of Information on Anxiety in Patients during Outpatient Surgery: A Systematic Review)

  • 정애리;이인숙
    • Perspectives in Nursing Science
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    • 제13권1호
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    • pp.48-57
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    • 2016
  • Purpose: The purpose of this study was to investigate the research methods, contents, and effects of providing information to alleviate patients' anxiety during outpatient surgery. Methods: The PICOTS-SD (Participants, Interventions, Comparisons, Outcomes, Time, Setting, Study design) was used and 11 randomized controlled trials studies that met the inclusion and exclusion criteria were selected. For assessing the quality of the studies, the Cochrane Risk of Bias tool was used. Results: In the 11 selected studies, intervention methods included verbal, written paper, video, and websites, and the outcome variable was anxiety. Regarding the effectiveness of providing information on anxiety, the result of the present study was ambivalent. Conclusion: This study showed the current trends in providing information as an intervention. However, randomized controlled trials are further needed in Korea, to verify the effects of such an intervention on patients' anxiety.

국내 장애 아동을 위한 언어치료용 모바일 어플리케이션 현황 분석 (Analysis of Mobile Application Trends for Speech and Language Therapy of Children with Disabilities in Korea)

  • 이영미;이수복;성민경
    • 말소리와 음성과학
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    • 제7권3호
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    • pp.153-163
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    • 2015
  • This study investigated the trends of mobile applications which were developed for prompting speech and language skills for children with disabilities, and analyzed the function and contents of these applications as a tool of speech and language therapy. For this analysis, twenty applications among 71 ones were selected according to the exclusion criteria. These applications were classified by the 8 using types of contents and analyzed the function of mobile applications by the revised mobile contents evaluation standard (ease of use, value of education, interest level, and interactivity). As a results, applications for augmentative and alternative communication were developed much more than any other types. And the ease of use got the highest score whereas the interest level got the lowest score in whole evaluation analysis. The result of this study would suggest way to evaluate applications for speech language therapy and to contribute to developing the contents and function of mobile applications aims to help children with disabilities improving their speech and language skills.

자하거약침의 부인과 질환 임상 연구에 대한 고찰 (The Review on Trend of Clinical Studies of Hominis Placenta Pharmacopuncture on Obstetrics & Gynecology Diseases)

  • 최수지;김동일
    • 대한한방부인과학회지
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    • 제32권1호
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    • pp.15-25
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    • 2019
  • Objectives: The aim of this study is to review clinical studies of Hominis Placenta Pharmacopuncutre on Obstetrics & Gynecology diseases. Methods: Key words "Jahageo Yakchim", "Hominis Placenta Pharmacopuncture", "Human Placenta Pharmacopuncture", "Hominis Placenta Pharmacoacupuncutre" were searched on 6 database systems (DBpia, KISS, KTKP, NDSL, Pubmed, CENTRAL) on August 31th 2018. Results: 1 case reports and 4 controlled studies were collected in accordance with the selection and exclusion criteria. The study design, study results and method of intervention were analyzed. Conclusions: This review shows the necessity of large-scale well designed clinical studies of Hominis Placenta Pharmacopuncture on Obstetrics & Gynecology diseases to evaluate the efficacy and safety.

Efficacy of probiotics for managing infantile colic due to their anti-inflammatory properties: a meta-analysis and systematic review

  • Shirazinia, Reza;Golabchifar, Ali Akbar;Fazeli, Mohammad Reza
    • Clinical and Experimental Pediatrics
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    • 제64권12호
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    • pp.642-651
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    • 2021
  • Background: Infantile colic (IC) is excessive crying in otherwise healthy children. Despite vast research efforts, its etiology remains unknown. Purpose: Most treatments for IC carry various side effects. The collection of evidence may inform researchers of new strategies for the management and treatment of IC as well as new clues for understanding its pathogenesis. This review and meta-analysis aimed to evaluate the efficacy and possible mechanisms of probiotics for mananaging IC. Methods: Ten papers met the study inclusion and exclusion criteria, and the meta-analysis was conducted using Review Manager (RevMan) software and a random-effects model. Results: This meta-analysis revealed that probiotics are effective for treating infantile colic, while the review showed that this efficacy may be due to their anti-inflammatory effects. Conclusion: Probiotics may be an important treatment option for managing infantile colic due to their anti-inflammatory properties.

경증 및 아임상 우울증의 중의학 임상연구 동향 분석 - China National Knowledge Infrastructure를 중심으로 - (The Analysis of Clinical Trial Research Trend on Mild and Sub-clinical Depression in Traditional Chinese Medicine - using China National Knowledge Infrastructure Database -)

  • 고유미;이시우;김상혁
    • 대한예방한의학회지
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    • 제19권1호
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    • pp.47-59
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    • 2015
  • Objective : The purpose of this study was to analyze the trend of clinical research on 'mild and sub-clinical depressions' in China. Method : The journal search was performed using China National Knowledge Infrastructure(CNKI). Our inclusion criteria were as follows: TCM clinical trials for mild, sub-clinical, early stage of depression. Exclusion criteria were the following: non-TCM clinical trials, disease-associated depression related clinical trials. Results : We included 16 papers in this study. 1. In this study, we realized there have been several mild and sub-clinical depressions related clinical trials conducted in the field of TCM. 2. The result of 10 Journals used the Hamilton Depression Rating Scale for diagnosis and assessment criteria of mild and sub-clinical depressions. 3. The selected journals categorized by various interventions, such as, herbal medicine(7), acupuncture(4), miscellaneous(5). 4. Also, 7 Journals showed the significant improvements in patients with mild and sub-clinical depressions by TCM interventions, and 5 studies of TCM patent prescription reported that herbal medicine therapy has less side effect than the western medicine. Conclusion : Through this study, we found out that several researchers in China performed clinical trials on mild and sub-clinical depressions constantly. From the result of this study, we need to concern about the necessity of research on the mild and sub-clinical depression in Korea. Therefore, this result could be used as a meaningful reference for the design of future clinical trials.

인공발목관절의 임상시험 가이드라인 개발을 위한 문헌적 고찰 (Review of Literatures for Development of Clinical Trial Guideline for Total Ankle Arthroplasty)

  • 박진오;이모세;이진우;이수빈;한승환
    • 대한족부족관절학회지
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    • 제18권4호
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    • pp.195-201
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    • 2014
  • Purpose: The purpose of this study is to develop guidelines for clinical trial of the total ankle replacement system for premarket approval. Materials and Methods: We selected and analyzed nine peer-reviewed articles whose quality had been proven in a previous phase. Two investigators extracted parameters for guideline criteria, including number of cases, patient age, follow-up period, failure rate, radiographic osteolysis rate, residual pain rate, and percentage of satisfaction. In addition, the inclusion and exclusion criteria were analyzed and developed. Results: Eight level IV studies and one level II study were included. The average number of cases was 159 cases and the mean patient age was 63.5 years. The mean follow-up period was 4.2 years, ranging from two to nine. The average failure rate of total ankle replacement in mid- to long-term follow-up was approximately 13% (2%~32.3%). The rate of osteolysis was approximately 18%. Residual pain was common (21.4%~46%), but overall patient satisfaction was approximately 85.6% (67.5%~97%). Conclusion: The results could be used as criteria for designing the clinical studies, such as number of cases, patient age (over 60 years), and follow-up period (minimum two years). The clinical scoring system and 36-item short form health survey (SF-36) was the most commonly used method for clinical evaluation for total ankle arthroplasty. In addition, the overall results, including failure rate, osteolysis rate, and patient satisfaction, could be used as a parameter of guidelines for premarket approval.

Comparison of minimally invasive versus conventional open harvesting technique for iliac bone graft in secondary alveolar bone grafting in cleft palate patients: a systematic review

  • Saha, Aditi;Shah, Sonal;Waknis, Pushkar;Bhujbal, Prathamesh;Aher, Sharvika;Vaswani, Vibha
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제45권5호
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    • pp.241-253
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    • 2019
  • This study evaluated and compared the donor site morbidity following minimally invasive and conventional open harvesting of iliac bone for secondary alveolar bone grafting in cleft palate patients. A thorough electronic search of PubMed, Google Scholar, EMBASE, and an institutional library and manual search of various journals was done; Inclusion criteria: 1) full-text articles using a minimally invasive or conventional open harvesting technique for iliac bone for secondary alveolar grafting in cleft palate patients and 2) articles published between January 1, 2001 and June 30, 2017 and Exclusion criteria: 1) articles published in languages other than English, 2) case reports, case series, animal studies, in vitro studies, and letters to the editor, and 3) full-text article unavailable even after writing to the authors. Preliminary screening of 274 studies excluded 223 studies for not meeting the eligibility criteria. Of the remaining 51 studies, 19 were removed for being duplicates. Of the remaining 32 studies, 15 were excluded after reading the abstract. Of the 17 studies that were left, 2 were excluded because they were in a language other than English, and 2 were excluded because the study group did not mention cleft palate patients. Thus, 13 studies providing results for a total of 654 patients were included in this qualitative synthesis. Minimally invasive bone graft harvest techniques are better than the conventional open iliac bone harvest method because they offer shorter operative time, decreased requirement for pain medications, less pain on discharge, and a shorter hospital stay.